The NOD mouse model of type 1 diabetes: As good as it gets?

Atkinson, Mark A., Leiter, Edward H.·1999·Nature Medicine

Cited by (593)

Items 201–300 of 593

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    John P. Driver, Oded Foreman, Chantal Mathieu, Evelyne van Etten, DAVID V. SERREZE · 2007 · Clinical & Experimental Immunology
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    Francesco Vendrame, Peter A. Gottlieb · 2004 · Endocrinology and Metabolism Clinics of North America
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    Takuma Hayashi · 2003 · Recent Progress in Hormone Research
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    Ruth Damaris Molano, Antonello Pileggi, Thierry Berney, Raffaella Poggioli, Elsie Zahr, Robert Oliver, Camillo Ricordi, David M. Rothstein, Giacomo P Basadonna, Luca Inverardi · 2003 · Diabetes
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    Leila Makhlouf, A. Yamada, Toshiro Ito, R. Abdi, M. Ansari, C. Khuong, H. Winn, H. Auchincloss, M. Sayegh · 2003 · Journal of the American Society of Nephrology
  8. Active Tolerance Induction and Prevention of Autoimmune Diabetes by Immunogene Therapy Using Recombinant Adenoassociated Virus Expressing Glutamic Acid Decarboxylase 65 Peptide GAD500–585
    Gencheng Han, Yan Li, Jianan Wang, Renxi Wang, Guojiang Chen, Lun Song, Ruonan Xu, Ming Yu, Xiaobing Wu, Jiahua Qian et al. · 2005 · The Journal of Immunology
  9. Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody1
    Ruth Damaris Molano, Antonello Pileggi, Thierry Berney, Raffaella Poggioli, Elsie Zahr, Robert Oliver, Thomas R. Malek, Camillo Ricordi, Luca Inverardi · 2003 · Transplantation
  10. CCR7 Deficiency in NOD Mice Leads to Thyroiditis and Primary Hypothyroidism
    Andrea P. Martin, Tatjana Marinković, Claudia Canasto‐Chibuque, Rauf Latif, Jay C. Unkeless, Terry F. Davies, Yousuke Takahama, Gláucia C. Furtado, Sérgio A. Lira · 2009 · The Journal of Immunology
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  12. Can We Change the Course of Beta-Cell Destruction in Type 1 Diabetes?
    Edwin AM Gale · 2002 · New England Journal of Medicine
  13. Contrast-enhanced ultrasound measurement of pancreatic blood flow dynamics predicts type 1 diabetes progression in preclinical models
    Joshua R. St. Clair, David G. Ramirez, Samantha Passman, Richard K.P. Benninger · 2018 · Nature Communications
  14. During the Early Prediabetic Period in NOD Mice, the Pathogenic CD8+ T-Cell Population Comprises Multiple Antigenic Specificities
    Teresa P. DiLorenzo, Scott M. Lieberman, Toshiyuki Takaki, Shinichiro Honda, Harold D. Chapman, Pere Santamaría, DAVID V. SERREZE, Stanley G. Nathenson · 2002 · Clinical Immunology
  15. Presence of Diabetes-Inhibiting, Glutamic Acid Decarboxylase-Specific, IL-10-Dependent, Regulatory T Cells in Naive Nonobese Diabetic Mice
    Sylvaine You, Cyndi Chen, Wen-Hui Lee, Todd M. Brusko, Mark A. Atkinson, Chih‐Pin Liu · 2004 · The Journal of Immunology
  16. Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes
    Dariush Mokhtari, Nils Welsh · 2009 · Clinical Science
  17. Autologous Hematopoietic Stem Cell Transplantation for Type 1 Diabetes
    Júlio César Voltarelli, Carlos Eduardo Barra Couri, Ana Beatriz P. L. Stracieri, Maria Carolina Oliveira, Daniela A. Moraes, Fabiano Pieroni, George Maurício Navarro Barros, Maria Isabel Ayrosa Madeira, Kelen Cristina Ribeiro Malmegrim, Maria Cristina Foss‐Freitas et al. · 2008 · Annals of the New York Academy of Sciences
  18. Therapeutic Prospects of Cannabinoids in the Immunomodulation of Prevalent Autoimmune Diseases
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  19. Rapamycin in islet transplantation: friend or foe?
    Thierry Berney, Antonio Secchi · 2008 · Transplant International
  20. Long-Term Reversal of Established Autoimmunity upon Transient Blockade of the LFA-1/Intercellular Adhesion Molecule-1 Pathway
    Lydia Bertry-Coussot, Bruno Lucas, Claire J. Danel, Lise Halbwachs‐Mecarelli, Jean‐François Bach, Lucienne Chatenoud, Patricia Lemarchand · 2002 · The Journal of Immunology
  21. Hyperalgesia in non-obese diabetic (NOD) mice: A role for the inducible bradykinin B1 receptor
    Bichoy H. Gabra, Pierré Sirois · 2005 · European Journal of Pharmacology
  22. Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb
    Yaming Liang, Tammy T. Huang, Chunyan Zhang, Ivan Todorov, Mark A. Atkinson, FOUAD R. KANDEEL, Stephen J. Forman, Defu Zeng · 2004 · Blood
  23. Glutamic acid decarboxylase autoimmunity in Batten disease and other disorders
    David A. Pearce, Mark A. Atkinson, Danilo A. Tagle · 2004 · Neurology
  24. IMMUNOTHERAPY WITH NONDEPLETING ANTI-CD4 MONOCLONAL ANTIBODIES BUT NOT CD28 ANTAGONISTS PROTECTS ISLET GRAFT IN SPONTANEOUSLY DIABETIC NOD MICE FROM AUTOIMMUNE DESTRUCTION AND ALLOGENEIC AND XENOGENEIC GRAFT REJECTION1
    Zhiguang Guo, Tao Wu, Nicole Kirchhof, Deepak Mital, James W. Williams, Miyuki Azuma, David E.R. Sutherland, Bernhard J. Hering · 2001 · Transplantation
  25. Pristane-induced autoimmunity in germ-free mice
    Akiei Mizutani, Victoria M. Shaheen, Hideo Yoshida, Jun Akaogi, Yoshiki Kuroda, Dina C. Nacionales, Yoshioki Yamasaki, Michito Hirakata, Nobutaka Ono, Westley H. Reeves et al. · 2004 · Clinical Immunology
  26. Reversal of Sjögren's-like syndrome in non-obese diabetic mice
    Simon D. Tran, Shohta Kodama, Beatrijs M. Lodde, Ildikó Szalayova, Sharon Key, Saeed Khalili, Denise Louise Faustman, Éva Mezey · 2006 · Annals of the Rheumatic Diseases
  27. The Pathogenesis of Diabetes in the NOD Mouse
    Michelle Solomon, Nora Sarvetnick · 2004 · Advances in immunology
  28. Molecular Analysis of an Echovirus 3 Strain Isolated from an Individual Concurrently with Appearance of Islet Cell and IA-2 Autoantibodies
    Çiğdem H. Williams, Sami Oikarinen, Sisko Tauriainen, Kimmo Salminen, Heikki Hyöty, Glyn Stanway · 2006 · Journal of Clinical Microbiology
  29. The CVB and Etiology of Type 1 Diabetes
    Kristen M. Drescher, Steven Tracy · 2008 · Springer eBooks
  30. Parasitic Nematodes, Proteinases and Transgenic Plants
    Catherine J. Lilley, P Devlin, Peter E. Urwin, Howard J. Atkinson · 1999 · Parasitology Today
  31. Acute Response of Peripheral Blood Cell to Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetic Patient
    Xiaofang Zhang, Lei Ye, Jiong Hu, Wei Tang, Ruixin Liu, Minglan Yang, Jie Hong, Weiqing Wang, Guang Ning, Weiqiong Gu · 2012 · PLoS ONE
  32. The Spleen as an Optimal Site for Islet Transplantation and a Source of Mesenchymal Stem Cells
    Naoaki Sakata, Gumpei Yoshimatsu, Shohta Kodama · 2018 · International Journal of Molecular Sciences
  33. The BB Rat as a Model of Human Type 1 Diabetes
    Rita Bortell, Chaoxing Yang · 2012 · Methods in molecular biology
  34. Zinc supplementation alleviates hyperglycemia and associated metabolic abnormalities in streptozotocin-induced diabetic rats
    Susmita Barman, Krishnapura Srinivasan · 2016 · Canadian Journal of Physiology and Pharmacology
  35. Invariant NKT Cells Exacerbate Type 1 Diabetes Induced by CD8 T Cells
    Thibault Griseri, Lucie Beaudoin, Jan Novák, Lennart T. Mars, Françoise Lepault, Roland Liblau, Agnès Lehuen · 2005 · The Journal of Immunology
  36. Early Th1 Response in Unprimed Nonobese Diabetic Mice to the Tyrosine Phosphatase-Like Insulinoma-Associated Protein 2, an Autoantigen in Type 1 Diabetes
    Sylvie Trembleau, Giuseppe Penna, Silvia Gregori, Giovanni Magistrelli, Antonella Isacchi, Luciano Adorini · 2000 · The Journal of Immunology
  37. Variations in Rodent Models of Type 1 Diabetes: Islet Morphology
    Lesya Novikova, Irina V. Smirnova, Sonia Rawal, Abby L. Dotson, Stephen H. Benedict, Lisa Stehno‐Bittel · 2013 · Journal of Diabetes Research
  38. Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
    M. Brehm, A. Powers, L. Shultz, D. Greiner · 2012 · Cold Spring Harbor Perspectives in Medicine
  39. Prevention of Type 1 Diabetes in the Rat With an Allele-Specific Anti–T-Cell Receptor Antibody
    Zhijun Liu, Laura Cort, Ryan A. Eberwine, Thomas Herrmann, Jean Leif, Dale L. Greiner, Barak Yahalom, Elizabeth P. Blankenhorn, John P. Mordes · 2012 · Diabetes
  40. Animal models of human type 1 diabetes for evaluating combination therapies and successful translation to the patient with type 1 diabetes
    Sigurd Lenzen · 2017 · Diabetes/Metabolism Research and Reviews
  41. Enhanced Recombinant Adeno-Associated Virus-Mediated Vascular Endothelial Growth Factor Expression in the Adult Mouse Retina
    P. Elizabeth Rakoczy, Meliha Brankov, Angela Mary Fonceca, Tammy Zaknich, Ben C. Rae, Chooi‐May Lai · 2003 · Diabetes
  42. Inducing tolerance to MHC-matched allogeneic islet grafts in Diabetic NOD mice by simultaneous islet and bone marrow transplantation under nonirradiative and nonmyeloablative conditioning therapy
    Tao Wu, Brett K. Levay‐Young, Neal D. Heuss, Hakan Sözen, Nicole Kirchhof, David E.R. Sutherland, Bernhard J. Hering, Zhiguang Guo · 2002 · Transplantation
  43. Treatment with Sulfatide or its Precursor, Galactosylceramide, Prevents Diabetes in NOD Mice
    Karsten Buschard, K. Hanspers, Pam Fredman, Eva‐Pia Reich · 2001 · Autoimmunity
  44. β‐cell‐specific IL‐35 therapy suppresses ongoing autoimmune diabetes in NOD mice
    Fatima Manzoor, Mark C. Johnson, Chengwen Li, Richard Jude Samulski, Bo Wang, Roland Tisch · 2016 · European Journal of Immunology
  45. Type 1A Diabetes Induced by Infection and Immunization
    David T. Robles, George S. Eisenbarth · 2001 · Journal of Autoimmunity
  46. Micronutrients and the Risk of Type 1 Diabetes: Vitamin D, Vitamin E, and Nicotinamide
    Elina Hyppönen · 2004 · Nutrition Reviews
  47. Evaluating Preclinical Efficacy
    Atkinson, Mark A. · 2011 · Science Translational Medicine
  48. Active Subjects with Autoimmune Type 1 Diabetes have Better Metabolic Profiles than Sedentary Controls
    Michela Adamo, Roberto Codella, Francesca Casiraghi, Anna Ferrulli, Concetta Macrì, Elena Bazzigaluppi, Ileana Terruzzi, Luca Inverardi, Camillo Ricordi, Livio Luzi · 2016 · Cell Transplantation
  49. Two-Photon Dye Cocktail for Dual-Color 3D Imaging of Pancreatic Beta and Alpha Cells in Live Islets
    Bikram Keshari Agrawalla, Hyo Won Lee, Wut Hmone Phue, Anandhkumar Raju, Jong-Jin Kim, Hwan Myung Kim, Nam‐Young Kang, Young‐Tae Chang · 2017 · Journal of the American Chemical Society
  50. Immune assessments in developmental and juvenile toxicology: Practical considerations for the regulatory safety testing of pharmaceuticals
    Paul Barrow, Guillaume Ravel · 2005 · Regulatory Toxicology and Pharmacology
  51. Making new beta cells from stem cells
    Alan Colman · 2004 · Seminars in Cell and Developmental Biology
  52. Developmental vitamin D3 deficiency induces alterations in immune organ morphology and function in adult offspring
    Louise Harvey, Thomas H.J. Burne, John Joseph McGrath, Darryl Walter Eyles · 2010 · The Journal of Steroid Biochemistry and Molecular Biology
  53. Lymphocytes with Aberrant Expression of Fas or Fas Ligand Attenuate Immune Bone Marrow Failure in a Mouse Model
    Stephanie O. Omokaro, Marie J. Desierto, Michael Eckhaus, Felicia M. Ellison, Jichun Chen, Neal S. Young · 2009 · The Journal of Immunology
  54. Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond
    Nick Giannoukakis, Brett Eugene Phillips, Massimo Trucco · 2008 · Pediatric Diabetes
  55. Gene Expression Profiles Define a Key Checkpoint for Type 1 Diabetes in NOD Mice
    Sarah Eckenrode, Qingguo Ruan, Ping Chang Yang, Weipeng Zheng, Richard McIndoe, Jin‐Xiong She · 2004 · Diabetes
  56. Deficiencies in Gut NK Cell Number and Function Precede Diabetes Onset in BB Rats
    Derrick J. Todd, Eric M. Forsberg, Dale L. Greiner, John P. Mordes, Aldo A. Rossini, Rita Bortell · 2004 · The Journal of Immunology
  57. Cathepsin L Inhibition Prevents Murine Autoimmune Diabetes via Suppression of CD8+ T Cell Activity
    Akiko Yamada, Naozumi Ishimaru, Rieko Arakaki, Nobuhiko Katunuma, Yoshio Hayashi · 2010 · PLoS ONE
  58. Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct
    Ellen Young, Paul R. Hess, Larry W. Arnold, Roland Tisch, Jeffrey A. Frelinger · 2009 · Autoimmunity
  59. Induction of Mixed Chimerism With MHC-Mismatched but Not Matched Bone Marrow Transplants Results in Thymic Deletion of Host-Type Autoreactive T-Cells in NOD Mice
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  60. Current State of Type 1 Diabetes Immunotherapy: Incremental Advances, Huge Leaps, or More of the Same?
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  61. Moderate Intensity Training Impact on the Inflammatory Status and Glycemic Profiles in NOD Mice
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  62. Why Can’t We Prevent Type 1 Diabetes?
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  63. ICA69null Nonobese Diabetic Mice Develop Diabetes, but Resist Disease Acceleration by Cyclophosphamide
    Shawn Winer, Igor A. Astsaturov, Roger Gaedigk, Denise Hammond-McKibben, Marc Pilon, Aihua Song, Violetta Kubiak, Wölfram Karges, Enrico Arpaia, Colin McKerlie et al. · 2002 · The Journal of Immunology
  64. Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes
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  65. Animal Models of Type 1 and Type 2 Diabetes Mellitus
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  66. The microbiology of human hygiene and its impact on type 1 diabetes
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  67. Developing tTA Transgenic Rats for Inducible and Reversible Gene Expression
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  68. Fatal attraction: chemokines and type 1 diabetes
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  69. Immune Regulation in T1D and T2D: Prospective Role of Foxp3+ Treg Cells in Disease Pathogenesis and Treatment
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  70. Protective Role for Plasmid DNA‐Mediated VIP Gene Transfer in Non‐Obese Diabetic Mice
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  71. Stimulation of the Developing Immune System Can Prevent Autoimmunity
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  72. Low Expression of Insulin in the Thymus of Non-obese Diabetic Mice
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  73. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice
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  74. β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes
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  75. Lower Frequency of CD62L high and Higher Frequency of TNFR2 + Tregs Are Associated with Inflammatory Conditions in Type 1 Diabetic Patients
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  76. T cell-driven initiation and propagation of autoimmune diabetes
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  77. The immunotherapeutic potential of dendritic cells in type 1 diabetes
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  78. Multifaceted Therapeutic Approaches for a Multigenic Disease
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  79. Of mice and men: use of animal models to identify possible interventions for the prevention of autoimmune type 1 diabetes in humans
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  80. Cannabidiol as an immune modulator: A comprehensive review
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  82. Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All-trans Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation
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  83. Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit
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  84. Effects of streptozotocin on autoimmune diabetes in NOD mice
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  85. The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice
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  86. Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development
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  90. Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1)
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  91. Implications of altered apoptosis in diabetes mellitus and autoimmune disease
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  93. Immunotherapeutic Approaches to Prevent, Ameliorate, and Cure Type 1 Diabetes
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  95. Endothelin inhibition delays onset of hyperglycemia and associated vascular injury in type I diabetes: Evidence for endothelin release by pancreatic islet β-cells
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  96. NOD Mice—Good Model for T1D but Not Without Limitations
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  97. Genetic control of non obese diabetic mice susceptibility to high-dose streptozotocin-induced diabetes
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  98. Anti-Idiotypic Antibody Specific to GAD65 Autoantibody Prevents Type 1 Diabetes in the NOD Mouse
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  99. Porcine IgE in the context of experimental food allergy: Purification and isotype-specific antibodies
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  100. Unexpected Sensitivity of Nonobese Diabetic Mice With a Disrupted Poly(ADP-Ribose) Polymerase-1 Gene to Streptozotocin-Induced and Spontaneous Diabetes
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