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Cited by 217Gastrointestinal motility and disordersEnhanced Recovery After SurgeryDiabetes Management and Research

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

A Small Particle Size Diet Reduces Upper Gastrointestinal Symptoms in Patients With Diabetic Gastroparesis: A Randomized Controlled Trial

Olausson, Eva A, Störsrud, Stine, Grundin, Håkan, Isaksson, Mats, Attvall, Stig, Simrén, Magnus·2014·American Journal of Gastroenterology
DOI 10.1038/ajg.2013.453
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Abstract

Objectives Gastroparesis is a well-known complication to diabetes mellitus (DM). Dietary advice is considered to be of importance to reduce gastrointestinal (GI) symptoms in patients with diabetic gastroparesis, but no randomized controlled trials exist. Our aim was to compare GI symptoms in insulin treated DM subjects with gastroparesis eating a diet with small particle size ("intervention diet") with the recommended diet for DM ("control diet"). Methods 56 subjects with insulin treated DM and gastroparesis were randomized to the intervention diet or the control diet. The patients received dietary advice by a dietitian at 7 occasions during 20 weeks. GI symptom severity, nutrient intake and glycemic control were measured before and after the intervention. Results A significantly greater reduction of the severity of the key gastroparetic symptoms-nausea/vomiting (P=0.01), postprandial fullness (P=0.02) and bloating (P=0.006)-were seen in patients who received the intervention diet compared with the control diet, and this was also true for regurgitation/heartburn (P=0.02), but not for abdominal pain. Anxiety was reduced after the intervention diet, but not after the control diet, whereas no effect on depression or quality of life was noted in any of the groups. A higher fat intake in the intervention group was noted, but otherwise no differences in body weight, HbA1c or nutrient intake were seen. Conclusions A small particle diet improves the key symptoms of gastroparesis in p…

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  1. 1993, The Diabetes Control and Complications Trial Research Group., N Engl J Med, 329, 977

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Metadata

Authors
Olausson, E. A., Störsrud, S., Grundin, H., Isaksson, M., Attvall, S., & Simrén, M.
Affiliations
University of Gothenburg (SE)
Corresponding author
Simrén, Magnus
ORCID
Venue
American Journal of Gastroenterology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2014-03
Volume
109
Issue
3
Pages
375-385
ISSN
0002-9270 (ISSN-L)
DOI
10.1038/ajg.2013.453
OpenAlex
W1991253050
Cited by
217
References
45
Citations by year
2026: 13 · 2025: 14 · 2024: 13 · 2023: 21 · 2022: 36 · 2021: 20 · 2020: 17 · 2019: 22 · 2018: 21 · 2017: 10 · 2016: 10 · 2015: 13 · 2014: 7
FWCI
13.28
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (unspecified)
Locations
  • The American Journal of Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords
diabetic gastroparesis, dietary intervention, upper gastrointestinal symptoms, nausea and vomiting, postprandial fullness, bloating, regurgitation, heartburn, insulin-treated diabetes, dietary recommendations, dietary fat intake, glycemic control
MeSH terms
Adult, Aged, Anxiety Disorders, Depressive Disorder, Diet, Diabetic, Feeding Behavior, Female, Humans, Insulin, Male, Middle Aged, Particle Size, Quality of Life, Surveys and Questionnaires, Radionuclide Imaging, Severity of Illness Index, Treatment Outcome, Gastroparesis, Upper Gastrointestinal Tract, Diabetes Complications

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