Cited by 127Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and AdiposityAdipose Tissue and Metabolism

The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.

Adiponectin and Hypertension

Ohashi, K., Ouchi, N., Matsuzawa, Y.·2011·American Journal of Hypertension

DOI 10.1038/ajh.2010.216

Open this paper in CoChat — free account

Abstract

Adipose tissue secretes a variety of bioactive molecules, also known as adipocytokines or adipokines. Obesity, in particular, visceral fat accumulation, is implicated in the dysregulated secretion of adipocytokines, which can contribute to the development of metabolic syndrome and cardiovascular diseases. Adiponectin is an adipocytokine that is exclusively secreted from adipose tissue, but its plasma levels are reduced in obese subjects, especially those with visceral fat accumulation. Adiponectin has a variety of protective properties against obesity-linked complications, such as hypertension, metabolic dysfunction, atherosclerosis, and ischemic heart disease. Adiponectin exerts the beneficial effects on vascular disorders by directly affecting components of vascular tissue. This review will discuss clinical and experimental findings that examine the role of adiponectin in regulation of hypertension and vascular function.

Integrity signals

Registry

Crossref · 10.1038/ajh.2010.216

Cites

82 of 82 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760
Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508
Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
Dahlöf, B., Devereux, R. B., Kjeldsen, S. E., Julius, S., Beevers, G., de Faire, U., Fyhrquist, F., Ibsen, H., Kristiansson, K., Lederballe-Pedersen, O., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08089-3 · Cited by 5,407
Leptin and the regulation of body weight in mammals
Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405
Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity
Arita, Y., Kihara, S., Ouchi, N., Takahashi, M., Maeda, K., Miyagawa, J.-I., Hotta, K., Shimomura, I., Nakamura, T., Miyaoka, K., et al. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0255 · Cited by 4,856
Self-citation
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664
A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes
Scherer, P. E., Williams, S. P., Fogliano, M., Baldini, G., & Lodish, H. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.26746 · Cited by 3,238
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., Sugiyama, T., Miyagishi, M., Hara, K., Tsunoda, M., et al. (2003) · Nature · doi:10.1038/nature01705 · Cited by 3,176
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial
Julius, S., Kjeldsen, S. E., Weber, M. A., Brunner, H. R., Ekman, S., Hansson, L., Hua, T. A., Laragh, J. H., McInnes, G. T., Mitchell, L., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16451-9 · Cited by 2,557

Flagged first, then by citations

Show all 82 references

Research works printed but not linked: 2

2003, 125, 1796
Furukawa, 2004, Journal of Clinical Investigation, 114, 1752, 10.1172/JCI200421625 · DOI · Paper page

Sorted by citations

Obesity, kidney dysfunction and hypertension: mechanistic links
Hall, J. E., do Carmo, J. M., da Silva, A. A., Wang, Z., & Hall, M. E. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0145-4 · Cited by 654
Perivascular adipose tissue: More than just structural support
Szasz, T., & Webb, R. C. (2012) · Clinical Science · doi:10.1042/cs20110151 · Cited by 265
Adipocytokines in relation to cardiovascular disease
de Voorde, J. V., Pauwels, B., Boydens, C., & Decaluwé, K. (2013) · Metabolism · doi:10.1016/j.metabol.2013.06.004 · Cited by 215
Mechanisms of Obesity-Induced Gastrointestinal Neoplasia
Alemán, J. O., Eusebi, L. H., Ricciardiello, L., Patidar, K. R., Sanyal, A. J., & Holt, P. R. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.11.051 · Cited by 201
The influence of perivascular adipose tissue on vascular homeostasis
Szasz, T., Bomfim, G. F., & Webb (2013) · Vascular Health and Risk Management · doi:10.2147/vhrm.s33760 · Cited by 205
Adiponectin Levels and the Risk of Hypertension
Kim, D. H., Kim, C., Ding, E. L., Townsend, M. K., & Lipsitz, L. A. (2013) · Hypertension · doi:10.1161/hypertensionaha.113.01453 · Cited by 165
Emerging Role of Adipocytokines in Type 2 Diabetes as Mediators of Insulin Resistance and Cardiovascular Disease
Jaganathan, R., Ravindran, R., & Dhanasekaran, S. (2017) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2017.10.040 · Cited by 154
Adiponectin as a routine clinical biomarker
Kishida, K., Funahashi, T., & Shimomura, I. (2013) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2013.08.006 · Cited by 149
PVAT and Its Relation to Brown, Beige, and White Adipose Tissue in Development and Function
Hildebrand, S., Stümer, J., & Pfeifer, A. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00070 · Cited by 143
Physiological, pathological and potential therapeutic roles of adipokines
Falcão‐Pires, I., Castro‐Chaves, P., Miranda‐Silva, D., Lourenço, A. P., & Leite-Moreira, A. F. (2012) · Drug Discovery Today · doi:10.1016/j.drudis.2012.04.007 · Cited by 131
The Role of Adiponectin in Endothelial Dysfunction and Hypertension
Rojas, E., Rodríguez-Molina, D., Bolli, P., Israili, Z. H., Faría, J., Fidilio, E., Bermúdez, V., & Velasco, M. (2014) · Current Hypertension Reports · doi:10.1007/s11906-014-0463-7 · Cited by 104
Bariatric surgery and bone disease: from clinical perspective to molecular insights
Folli, F. B., Sabowitz, B., Schwesinger, W. H., Fanti, P., Guardado‐Mendoza, R., & Muscogiuri, G. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.115 · Cited by 89
Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges
Lei, X., Qiu, S., Yang, G., & Wu, Q. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2022.10.018 · Cited by 91
Adiponectin: A biomarker for rheumatoid arthritis?
Chen, X., Lu, J., Bao, J., Guo, J., Shi, J., & Wang, Y. (2012) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2012.07.004 · Cited by 78
Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
Chiara, T. D., Argano, C., Corrao, S., Scaglione, R., & Licata, G. (2011) · Journal of Nutrition and Metabolism · doi:10.1155/2012/175245 · Cited by 69
Adiponectin Expression Protects against Angiotensin II-Mediated Inflammation and Accelerated Atherosclerosis
van Stijn, C. M. W., Kim, J., Barish, G. D., Tietge, U. J. F., & Tangirala, R. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086404 · Cited by 64
Pulmonary Hypertension and Obesity: Focus on Adiponectin
Perrotta, F., Nigro, E., Mollica, M., Costigliola, A., D’Agnano, V., Daniele, A., Bianco, A., & Guerra, G. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040912 · Cited by 58
Adiponectin and Hypertension in Normal-Weight and Obese Children
Brambilla, P., Antolini, L., Street, M. E., Giussani, M., Galbiati, S., Valsecchi, M. G., Stella, A., Zuccotti, G., Bernasconi, S., & Genovesi, S. (2012) · American Journal of Hypertension · doi:10.1093/ajh/hps033 · Cited by 53
A novel peptide adropin in cardiovascular diseases
Li, L., Xie, W., Zheng, X., Yin, W., & Tang, C. (2015) · Clinica Chimica Acta · doi:10.1016/j.cca.2015.12.010 · Cited by 52
Adipocytokines, C-Reactive Protein, and Cardiovascular Disease: A Population-Based Prospective Study
Seven, E., Husemoen, L. L. N., Sehested, T. S. G., Ibsen, H., Wachtell, K., Linneberg, A. R., & Jeppesen, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0128987 · Cited by 50
Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway
Nour‐Eldine, W., Ghantous, C. M., Zibara, K., Dib, L., Issa, H., Itani, H. A., Zein, N. E., & Zeidan, A. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00086 · Cited by 48
Exploring the potential of tocotrienol from Bixa orellana as a single agent targeting metabolic syndrome and bone loss
Wong, S. K., Chin, K., Suhaimi, F. H., Ahmad, F., & Ima-Nirwana, S. (2018) · Bone · doi:10.1016/j.bone.2018.07.003 · Cited by 45
Adipose Tissue as Regulator of Vascular Tone
Boydens, C., Maenhaut, N., Pauwels, B., Decaluwé, K., & de Voorde, J. V. (2012) · Current Hypertension Reports · doi:10.1007/s11906-012-0259-6 · Cited by 44
Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting
Grundler, F., Mesnage, R., Michalsen, A., & de Toledo, F. W. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.018649 · Cited by 45
Links between HPA axis and adipokines: clinical implications in paradigms of stress-related disorders
Papargyri, P., Zapanti, E. D., Salakos, N., Papargyris, L., Bargiota, Α., & Mastorakos, G. P. (2018) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2018.1543585 · Cited by 42
Adiponectin: a pleiotropic hormone with multifaceted roles
Shklyaev, S. S., Melnichenko, G. A., Volevodz, N. N., Falaleeva, N. A., Ivanov, S. A., Kaprin, A. D., & Mokrysheva, N. G. (2021) · Problems of Endocrinology · doi:10.14341/probl12827 · Cited by 44
The relationship between obesity associated weight-adjusted waist index and the prevalence of hypertension in US adults aged ≥60 years: a brief report
Wang, J., Yang, Q.-Y., Chai, D., Su, Y., Jin, Q.-Z., & Wang, J.-H. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1210669 · Cited by 37
Comparative Transcriptome Analysis of Key Genes and Pathways Activated in Response to Fat Deposition in Two Sheep Breeds With Distinct Tail Phenotype
Zhang, W., Xu, M., Wang, J., Wang, S., Wang, X., Yang, J., Gao, L., & Gan, S. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.639030 · Cited by 37
Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents
Wójcik, M., & Kozioł-Kozakowska, A. (2021) · Nutrients · doi:10.3390/nu13114032 · Cited by 44
Adiponectin Signaling and Metabolic Syndrome
Fu, Y. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-800101-1.00009-0 · Cited by 29
Association of adiponectin gene ( ADIPOQ ) polymorphisms with measures of obesity in Nigerian young adults
Ogundele, O. E., Adekoya, K. O., Osinubi, A. A., Awofala, A. A., & Oboh, B. O. (2017) · Egyptian Journal of Medical Human Genetics · doi:10.1016/j.ejmhg.2017.08.005 · Cited by 33
Expression of Adiponectin Receptors on Peripheral Blood Leukocytes of Hypertensive Children Is Associated with the Severity of Hypertension
Gackowska, L., Litwin, M., Trojanek, J., Eljaszewicz, A., Kubiszewska, I., Niemirska, A., Wierzbicka, A., & Michałkiewicz, J. (2015) · BioMed Research International · doi:10.1155/2015/742646 · Cited by 27
Arterial Stiffness Is Associated With Increased Monocyte Expression of Adiponectin Receptor mRNA and Protein in Patients With Coronary Artery Disease
Ikonomidis, I., Kadoglou, N. P. E., Tsiotra, P. C., Κόλλιας, Α., Palios, I. M., Fountoulaki, K., Halvatsiotis, P., Maratou, E., Dimitriadis, G., Kremastinos, D. T., et al. (2012) · American Journal of Hypertension · doi:10.1038/ajh.2012.42 · Cited by 27
PCOSKBR2: a database of genes, diseases, pathways, and networks associated with polycystic ovary syndrome
Sharma, M., Barai, R. S., Kundu, I., Bhaye, S., Pokar, K., & Idicula‐Thomas, S. (2020) · Scientific Reports · doi:10.1038/s41598-020-71418-8 · Cited by 26
Saffron ( Crocus sativus L.) in combination with resistance training reduced blood pressure in the elderly hypertensive men: A randomized controlled trial
Moghadam, B. H., Eskandari, M., Shabkhiz, F., Mojtahedi, S., & Mahmoudi, N. (2021) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.14746 · Cited by 26
Obesity, High-Molecular-Weight (HMW) Adiponectin, and Metabolic Risk Factors: Prevalence and Gender-Specific Associations in Estonia
Eglit, T., Ringmets, I., & Lember, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073273 · Cited by 26
Relative contribution of obesity and serum adiponectin to the development of hypertension
Jung, D., Kim, J., Kim, J.-K., Koh, S. B., Park, J.-K., & Ahn, S. V. (2013) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2013.09.018 · Cited by 26
Chronic effects of centrally administered adiponectin on appetite, metabolism and blood pressure regulation in normotensive and hypertensive rats
Bassi, M., do Carmo, J. M., Hall, J. E., & da Silva, A. A. (2012) · Peptides · doi:10.1016/j.peptides.2012.06.013 · Cited by 24
A Pilot Study of Telmisartan for Visceral Adiposity in HIV Infection: The Metabolic Abnormalities, Telmisartan, and HIV Infection (MATH) Trial
Lake, J. E., Tseng, C., & Currier, J. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058135 · Cited by 25
Association of Hypertension and Obesity with Risk Factors of Cardiovascular Diseases in Children Aged 6–9 Years Old in the Eastern Cape Province of South Africa
Matjuda, E. N., Engwa, G. A., Letswalo, P. B., Mungamba, M. M., Sewani-Rusike, C. R., & Nkeh-Chungag, B. N. (2020) · Children · doi:10.3390/children7040025 · Cited by 25
Circulating Des-acyl Ghrelin Improves Cardiovascular Risk Prediction in Older Hypertensive Patients
Yano, Y., Nakazato, M., Toshinai, K., Inokuchi, T., Matsuda, S., Hidaka, T., Hayakawa, M., Kangawa, K., Shimada, K., & Kario, K. (2013) · American Journal of Hypertension · doi:10.1093/ajh/hpt232 · Cited by 25
Adiponectin at Physiologically Relevant Concentrations Enhances the Vasorelaxative Effect of Acetylcholine via Cav-1/AdipoR-1 Signaling
Du, Y., Li, R., Lau, W. B., Zhao, J., Lopez, B., Christopher, T. A., Ma, X., & Wang, Y. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152247 · Cited by 24
Low adiponectin in overweight/obese women: association with diabetes during pregnancy.
Ianniello, F., Quagliozzi, L., Caruso, A., & Paradisi, G. (2013) · PubMed · Cited by 23
Adipokines protecting CKD
Miyamoto, S., & Sharma, K. (2013) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gft261 · Cited by 23
Deciphering endocrine function of adipose tissue and its significant influences in obesity-related diseases caused by its dysfunction
Duan, F., Wu, J., Chang, J., Peng, H., Liu, Z., Liu, P., Han, X., Sun, T., Shang, D., Yang, Y., et al. (2024) · Differentiation · doi:10.1016/j.diff.2024.100832 · Cited by 27
Independent associations of total and high molecular weight adiponectin with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in black and white patients with rheumatoid arthritis: a cross-sectional study
Dessein, P. H., Woodiwiss, A. J., Norton, G. R., Tsang, L., & Solomon, A. (2013) · Arthritis Research & Therapy · doi:10.1186/ar4308 · Cited by 22
Population-based Assessment of Cardiometabolic-related Diagnoses in Youth With Klinefelter Syndrome: A PEDSnet Study
Davis, S., Nokoff, N., Furniss, A., Pyle, L. L., Valentine, A., Fechner, P. Y., Ikomi, C., Magnusen, B., Nahata, L., Vogiatzi, M. G., et al. (2022) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgac056 · Cited by 21
The Therapeutic Role of Renin-Angiotensin System Blockers in Obesity- Related Renal Disorders
Santos, S. H. S., & Silva, A. C. S. E. (2014) · Current Clinical Pharmacology · doi:10.2174/15748847112079990050 · Cited by 21
Adiponectin in the Heart and Vascular System
Ding, M., Rzucidlo, E. M., Davey, J. C., Xie, Y., Liu, R., Jin, Y., Stavola, L. K., & Martin, K. A. (2012) · Vitamins and hormones · doi:10.1016/b978-0-12-398313-8.00011-7 · Cited by 21
Different Changes in Adipokines, Lipid Profile, and TNF-Alpha Levels between 10 and 20 Whole Body Cryostimulation Sessions in Individuals with I and II Degrees of Obesity
Pilch, W., Piotrowska, A., Wyrostek, J., Czerwińska‐Ledwig, O., Ziemann, E., Antosiewicz, J., Zasada, M., Kulesa-Mrowiecka, M., & Żychowska, M. (2022) · Biomedicines · doi:10.3390/biomedicines10020269 · Cited by 20
The follicular fluid adipocytokine milieu could serve as a prediction tool for fertility treatment outcomes
Wyse, B. A., Weizman, N. F., Defer, M. K., Montbriand, J., Száraz, P., & Librach, C. L. (2021) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2021.07.001 · Cited by 18
Gut permeability is associated with hypertension and measures of obesity but not with Endothelial Dysfunction in South African youth
Ntlahla, E. E., Mfengu, M. M., Engwa, G. A., Nkeh-Chungag, B. N., & Sewani-Rusike, C. R. (2021) · African Health Sciences · doi:10.4314/ahs.v21i3.26 · Cited by 17
Association of Adiponectin with Hypertension in Type 2 Diabetic Patients: the Gender Effect
Khabour, O. F., Wehaibi, S. H., Al-Azzam, S. I., Alzoubi, K. H., & El-Akawi, Z. J. (2012) · Clinical and Experimental Hypertension · doi:10.3109/10641963.2012.732645 · Cited by 17
Adropin as a novel energy factor likely has the ability to regulate blood pressure
Chen, M., Ouyang, F., & Zhou, S. (2015) · Medical Hypotheses · doi:10.1016/j.mehy.2015.04.010 · Cited by 17
Cardiovascular Risk Factors and Their Relationship with Vascular Dysfunction in South African Children of African Ancestry
Matjuda, E. N., Engwa, G. A., Anye, S. N. C., Nkeh-Chungag, B. N., & Goswami, N. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10020354 · Cited by 19
Glucocorticoid Replacement Affects Serum Adiponectin Levels and HDL-C in Patients With Secondary Adrenal Insufficiency
Hayashi, R., Tamada, D., Murata, M., Kitamura, T., Mukai, K., Maeda, N., Otsuki, M., & Shimomura, I. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2019-00420 · Cited by 16
Serial changes in adipocytokines and cardiac function in a rat model of the metabolic syndrome
Yamaguchi, T., Kitamori, K., Ichihara, G., Suzuki, Y., Ochiai, M., Yamada, Y., Tada‐Oikawa, S., Tsuchikura, S., Yamori, Y., & Ichihara, S. (2013) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12107 · Cited by 16
Blunted Blood Pressure Response and Elevated Plasma Adiponectin Levels in Female Sprague Dawley Rats
Kamari, Y., Peleg, E., Leibowitz, A., & Grossman, E. (2012) · American Journal of Hypertension · doi:10.1038/ajh.2011.260 · Cited by 16
Association of adiposity indicators with hypertension among Chinese adults
Wang, C., Fu, W., Cao, S., Xu, H., Tian, Q., Gan, Y., Guo, Y., Yan, S., Yan, F., Yue, W., et al. (2021) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.01.001 · Cited by 16
A Saccharomyces cerevisiae Assay System to Investigate Ligand/AdipoR1 Interactions That Lead to Cellular Signaling
Aouida, M., Kim, K.-C., Shaikh, A. R., Pardo, J. M., Eppinger, J., Yun, D., Bressan, R. A., & Narasimhan, M. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065454 · Cited by 15
Serum adiponectin levels are inversely correlated with leukemia: A meta-analysis
Ma, J., Shang, J., Wang, H., Sui, J., Liu, K., & Du, J. (2016) · Journal of Cancer Research and Therapeutics · doi:10.4103/0973-1482.186695 · Cited by 15
Can improvements in sleep quality positively affect serum adiponectin-levels in patients with obstructive sleep apnea?
Magnúsdóttir, S., THOMAS, R. J., & Hilmisson, H. (2021) · Sleep Medicine · doi:10.1016/j.sleep.2021.05.032 · Cited by 16
The potential mechanisms underlying the modulating effect of perirenal adipose tissue on hypertension: Physical compression, paracrine, and neurogenic regulation
Sun, J.-Y., Su, Z., Yang, J., Sun, W. Y., & Kong, X. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122511 · Cited by 14
Gender differences in the relationship between blood pressure and body mass index during adolescence
Kawada, N., Nakanishi, K., Ohama, T., Nishida, M., Yamauchi‐Takihara, K., & Moriyama, T. (2014) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2014.07.001 · Cited by 14
Time-dependent changes of plasma adiponectin concentration in relation to coronary microcirculatory function in patients with acute myocardial infarction treated by primary percutaneous coronary intervention
Trifunović, D., Stankovic, S. D., Marinković, J., Beleslin, B., Banovic, M. D., Djukanović, N., Orlic, D. N., Tesic, M. B., Vujisic-Tesic, B. D., Petrovic, M., et al. (2014) · Journal of Cardiology · doi:10.1016/j.jjcc.2014.05.011 · Cited by 14
Resistance Training Promotes Reduction in Blood Pressure and Increase Plasma Adiponectin of Hypertensive Elderly Patients
Montrezol, F. T. (2013) · Journal of Hypertension Open Access · doi:10.4172/2167-1095.1000185 · Cited by 14
Alterations to adipose tissue morphology during inflammatory arthritis is indicative of vasculopathology in DBA/1 mice
Sime, K., Choy, E., & Williams, A. S. (2017) · Adipocyte · doi:10.1080/21623945.2017.1295174 · Cited by 13
Abdominal fat and blood pressure in healthy young children
Jansen, M. A. C., Uiterwaal, C. S. P. M., Visseren, F. L. J., van der Ent, C. K., Grobbee, D. E., & Dalmeijer, G. W. (2016) · Journal of Hypertension · doi:10.1097/hjh.0000000000000996 · Cited by 13
ACE Gene Plays a Key Role in Reducing Blood Pressure in The Hyperintensive Elderly After Resistance Training
Montrezol, F. T., Marinho, R., da Mota, G. D. F. A., D’Almeida, V., de Oliveira, E. M., Gomes, R. J., & Medeiros, A. (2017) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000002355 · Cited by 13
High adiponectin levels fail to protect against the risk of hypertension and, in women, against coronary disease: involvement in autoimmunity?
Onat, A., Aydın, M., Can, G., Köroğlu, B., Karagöz, A., & Altay, S. (2013) · World Journal of Diabetes · doi:10.4239/wjd.v4.i5.219 · Cited by 13
Contribution of body composition components and soft‐tissue biochemical factors to genetic variation of body mass index (BMI) in an ethnically homogeneous population
Dosaev, T., Prakash, J., & Livshits, G. (2014) · American Journal of Human Biology · doi:10.1002/ajhb.22583 · Cited by 12
The Evolving Interplay among Abundant Adipokines in Patients with Hepatitis C during Viral Clearance
Chang, M., Chen, T., Hsu, C., Lin, C.-H., Lin, C.-Y., Kuo, C., Huang, S.-W., Chen, C.-W., Cheng, H., Yeh, C., et al. (2017) · Nutrients · doi:10.3390/nu9060570 · Cited by 11
Plasma Adiponectin and Blood Pressure Progression in African Americans: The Jackson Heart Study
Kazé, A. D., Musani, S. K., Bidulescu, A., Correa, A., Golden, S. H., Bertoni, A. G., & Echouffo-Tcheugui, J. B. (2021) · American Journal of Hypertension · doi:10.1093/ajh/hpab101 · Cited by 11
Effect of Extended-Release Niacin/Laropiprant Combination on Plasma Adiponectin and Insulin Resistance in Chinese Patients with Dyslipidaemia
Hu, M., Yang, Y., Masuda, D., Yamashita, S., & Tomlinson, B. (2015) · Disease Markers · doi:10.1155/2015/154014 · Cited by 10
Factors Related with Adiponectinemia in Obese and Normal-Weight Women and with Its Variation in Weight Loss Programs
Silva‐Nunes, J., Oliveira, A., Duarte, L., Barradas, M., Melão, A., Brito, M., & Veiga, L. (2013) · Obesity Facts · doi:10.1159/000350664 · Cited by 10
Rosiglitazone lowers resting and blood pressure response to exercise in men with type 2 diabetes: A 1‐year randomized study
Piché, M., Laberge, A., Brassard, P., Arsenault, B. J., Bertrand, O. F., Després, J., Costerousse, O., & Poirier, P. (2018) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13293 · Cited by 10
Effect of L-arginine on Markers of Metabolic Syndrome Related to Abdominal Obesity And Disorder of Lipid Metabolism in Female Wistar Albino Rats
Egbuonu, A. C. C., & S, E. L. U. (2012) · American Journal of Biochemistry · doi:10.5923/j.ajb.20120202.02 · Cited by 9
Adiponectin: A biomarker for chronic hepatitis C?
Liu, D., Li, S., & Li, Z. (2015) · Cytokine · doi:10.1016/j.cyto.2015.10.016 · Cited by 9
ADIPONECTIN: BENEFICIAL EFFECTS ON METABOLIC AND CARDIOVASCULAR DYSFUNCTIONS
Соломоновна, П. Н., & Tanyanskiy, D. A. (2013) · Arterial’naya Gipertenziya (Arterial Hypertension) · doi:10.18705/1607-419x-2013-19-1-84-96 · Cited by 8
Relation of visceral fat and haemodynamics in adults with Fontan circulation
Lubert, A. M., Alsaied, T., Trout, A. T., Dillman, J. R., & Goldstein, B. H. (2020) · Cardiology in the Young · doi:10.1017/s1047951120001419 · Cited by 8
AT1 receptors modulate ethanol-induced loss of anticontractile effect of perivascular adipose tissue
Awata, W. M. C., Sousa, A. H., de Mello, M. M. B., Dourado, T. M. H., Pinheiro, L. C., Elias‐Oliveira, J., Rodrigues, V. F., Carlos, D., de Castro, M. M., & Tirapelli, C. R. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115840 · Cited by 7
Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries
Dreier, R., Asferg, C. L., Berg, J. O., Andersen, U. B., Flyvbjerg, A., Frystyk, J., Linneberg, A. R., Jeppesen, J., Edvinsson, L. I., & Skovsted, G. F. (2015) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12452 · Cited by 7
Urinary adiponectin and albuminuria in non-diabetic hypertensive patients: an analysis of the ESPECIAL trial
Han, S. S., Bae, E., Ahn, S. Y., Kim, S., Park, J. H., Shin, S. J., Lee, S. H., Choi, B. S., Chin, H. J., Lim, C. S., et al. (2015) · BMC Nephrology · doi:10.1186/s12882-015-0124-3 · Cited by 7
Increased Circulating ANG II and TNF-α Represents Important Risk Factors in Obese Saudi Adults with Hypertension Irrespective of Diabetic Status and BMI
Al‐Daghri, N. M., Dahman, L. S. B., Al-Attas, O. S., Saleem, T. H., Alokail, M. S., Alkharfy, K. M., Draz, H. M., Yakout, S. M., Mohamed, A. O., Harte, A. L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051255 · Cited by 8
Plasma amino acid profile is altered by visceral fat accumulation and is a predictor of visceral obesity in humansPreprint
Tanaka, T., Ishizaka, Y., Mitushima, T., Tani, M., Toda, A., Toda, E.-I., Okada, M., Yamamoto, H., & Yamakado, M. (2011) · Nature Precedings · doi:10.1038/npre.2011.5560.1 · Cited by 7
Perivascular adipose tissue and vascular inflammation: from biological insights to clinical implications
Sowa, H., Karasaki, K., Ishiwata, M., Cheng, X., Hashimoto, M., & Ueda, K. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1766197 · Cited by 7
Thicker Epicardial Adipose Tissue in Nonobese Hypertensive Patients: An Innocent Bystander or Overlooked Villain?
Wang, T., & Chen, M.-F. (2011) · American Journal of Hypertension · doi:10.1038/ajh.2011.155 · Cited by 6
Adiponectin Genotype, Blood Pressures, and Arterial Stiffness: The Cardiometabolic Risk in Chinese (CRC) Study
Liang, J., Qiu, Q., Gong, Y., Liu, X., Dou, L., Zou, C., Wang, Y., & Qi, L. (2015) · Journal of Clinical Hypertension · doi:10.1111/jch.12516 · Cited by 6
Differential expression of serum GBP-28, NBP-Cyc 3 and TIMP-1 complicates pregnancy in hypertensive disorder pregnancy
Hu, G., Xia, Z.-S., & Guo, X. (2021) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2021.103288 · Cited by 7
Adiponectin and Metabolic Syndrome in a Tunisian Population
Ali, S. B., Jemaa, R., Ftouhi, B., Kallel, A., Feki, M., Sliméne, H., & Kaabachi, N. (2011) · Inflammation · doi:10.1007/s10753-011-9383-8 · Cited by 6
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Levels in Hypertensive Patients: Speckle Tracking Echocardiography
Khairat, I., Khedr, L. A., & Werida, R. H. (2020) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-020-00398-7 · Cited by 6
Carotid artery longitudinal wall motion alterations associated with metabolic syndrome and insulin resistance
Taivainen, S. H., Laitinen, T. M., Yli‐Ollila, H., Juonala, M., Kähönen, M. A. P., Raitakari, O. T., & Laitinen, T. P. (2020) · Clinical Physiology and Functional Imaging · doi:10.1111/cpf.12687 · Cited by 5
Serum adiponectin level is not only decreased in metabolic syndrome but also in borderline metabolic abnormalities
Baden, M. Y., Yamada, Y., Obata, Y., Hosokawa, Y., Saisho, K., Tamba, S., Yamamoto, K., Umeda, M., Furubayashi, A., Tsukamoto, Y., et al. (2011) · Nutrition and Diabetes · doi:10.1038/nutd.2011.13 · Cited by 5
Self-citation
Analysis of left ventricular hypertrophy predictors in women with different levels of obesity
Постоева, А. В., Dvoryashina, I. V., Бахтина, З. Э., & Eliseeva, I. V. (2015) · Obesity and metabolism · doi:10.14341/omet2015434-41 · Cited by 5
Marrow adipose tissue gradient is preserved through high protein diet and bed rest. A randomized crossover study
Trudel, G., Melkus, G., Sheikh, A., Ramsay, T., & Laneuville, O. (2019) · Bone Reports · doi:10.1016/j.bonr.2019.100229 · Cited by 6
Reevaluating Adiponectin’s impact on obesity hypertension: a Chinese case-control study
Wu, O., Lu, X., Leng, J., Zhang, X., Liu, W. Y., Yang, F., Zhang, H., Li, J., Khederzadeh, S., Liu, X., et al. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-03865-4 · Cited by 4
Antihypertensive Effect of Dietary β-Conglycinin in the Spontaneously Hypertensive Rat (SHR)
Kawabeta, K., Yuasa, M., Sugano, M., & Koba, K. (2022) · Metabolites · doi:10.3390/metabo12050422 · Cited by 4
Obesity, impaired glucose regulation, metabolic syndrome and their associations with high-molecular-weight adiponectin levels
Eglit, T. (2014) · DSpace repository (University of Tartu) · Cited by 4
Assay Profiles of Prostanoids and Female Sex Hormones for Studying Potential Biomarkers of Hypertension
Jansen, G. W. S. A. (2013) · Journal of Hypertension Open Access · doi:10.4172/2167-1095.1000159 · Cited by 3
Association Between Chinese Visceral Adiposity Index and Risk of Incident Hypertension Among Older Adults: A Prospective Cohort Study
Gao, D., Chen, X., Liu, D., Su, D., Cheng, Y., Cui, Y., Hu, W., Li, Z., Li, G., Zhang, X., et al. (2025) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-025-00734-9 · Cited by 2

Authors: Ohashi, K., Ouchi, N., & Matsuzawa, Y.
Affiliations: Nagoya University (JP)
Sumitomo Hospital (JP)
ORCID: Ohashi, K.
Ouchi, N.
Venue: American Journal of Hypertension
Publisher: Oxford University Press (OUP)
Published: 2011-03-01
Volume: 24
Issue: 3
Pages: 263-269
ISSN: 0895-7061 (ISSN-L)
1941-7225
DOI: 10.1038/ajh.2010.216
OpenAlex: W1968290606
Cited by: 127
References: 82
Citations by year: 2026: 3 · 2025: 4 · 2024: 4 · 2023: 5 · 2022: 6 · 2021: 13 · 2020: 9 · 2019: 5 · 2018: 4 · 2017: 5 · 2016: 4 · 2015: 11 · 2014: 10 · 2013: 22 · 2012: 15
FWCI: 1.59
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Hypertension (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
Keywords: adiponectin, hypertension, adipokines, adipose tissue, visceral fat, obesity, metabolic syndrome, cardiovascular disease, atherosclerosis, ischemic heart disease, vascular function
MeSH terms: Animals, Endothelium, Vascular, Humans, Hypertension, Macrophages, Nitric Oxide, Renin-Angiotensin System, Biomarkers, Cyclooxygenase 2, Adiponectin

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Adiponectin and Hypertension

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks