Adiponectin and Hypertension

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760

Increased oxidative stress in obesity and its impact on metabolic syndrome

Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508

Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol

Dahlöf, B., Devereux, R. B., Kjeldsen, S. E., Julius, S., Beevers, G., de Faire, U., Fyhrquist, F., Ibsen, H., Kristiansson, K., Lederballe-Pedersen, O., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08089-3 · Cited by 5,407

Leptin and the regulation of body weight in mammals

Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

Arita, Y., Kihara, S., Ouchi, N., Takahashi, M., Maeda, K., Miyagawa, J.-I., Hotta, K., Shimomura, I., Nakamura, T., Miyaoka, K., et al. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0255 · Cited by 4,856

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

Scherer, P. E., Williams, S. P., Fogliano, M., Baldini, G., & Lodish, H. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.26746 · Cited by 3,238

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., Sugiyama, T., Miyagishi, M., Hara, K., Tsunoda, M., et al. (2003) · Nature · doi:10.1038/nature01705 · Cited by 3,176

Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial

Julius, S., Kjeldsen, S. E., Weber, M. A., Brunner, H. R., Ekman, S., Hansson, L., Hua, T. A., Laragh, J. H., McInnes, G. T., Mitchell, L., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16451-9 · Cited by 2,557

Novel Modulator for Endothelial Adhesion Molecules

Ouchi, N., Kihara, S., Arita, Y., Maeda, K., Kuriyama, H., Okamoto, Y., Hotta, K., Nishida, M., Takahashi, M., Nakamura, T., et al. (1999) · Circulation · doi:10.1161/01.cir.100.25.2473 · Cited by 2,158

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

Maeda, N., Shimomura, I., Kishida, K., Nishizawa, H., Matsuda, M., Nagaretani, H., Furuyama, N., Kondo, H., Takahashi, M., Arita, Y., et al. (2002) · Nature Medicine · doi:10.1038/nm724 · Cited by 2,114

cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)

Maeda, K., Okubo, K., Shimomura, I., Funahashi, T., Matsuzawa, Y., & Matsubara, K. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0587 · Cited by 2,081

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

Huang, P. L., Huang, Z., Mashimo, H., Bloch, K. D., Moskowitz, M. A., Bevan, J. A., & Fishman, M. C. (1995) · Nature · doi:10.1038/377239a0 · Cited by 2,070

Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-κB Signaling Through a cAMP-Dependent Pathway

Ouchi, N., Kihara, S., Arita, Y., Okamoto, Y., Maeda, K., Kuriyama, H., Hotta, K., Nishida, M., Takahashi, M., Muraguchi, M., et al. (2000) · Circulation · doi:10.1161/01.cir.102.11.1296 · Cited by 1,730

PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

Maeda, N., Takahashi, M., Funahashi, T., Kihara, S., Nishizawa, H., Kishida, K., Nagaretani, H., Matsuda, M., Komuro, R., Ouchi, N., et al. (2001) · Diabetes · doi:10.2337/diabetes.50.9.2094 · Cited by 1,673

Effect of Weight Loss and Lifestyle Changes on Vascular Inflammatory Markers in Obese Women: A Randomized Trial

Esposito, K., Pontillo, A., Di Palo, C., Giugliano, G., Masella, M., Marfella, R., & Giugliano, D. (2003) · JAMA · doi:10.1001/jama.289.14.1799 · Cited by 1,511

Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

Yokota, T., Oritani, K., Takahashi, I., Ishikawa, J., Matsuyama, A., Ouchi, N., Kihara, S., Funahashi, T., Tenner, A. J., Tomiyama, Y., et al. (2000) · Blood · doi:10.1182/blood.v96.5.1723 · Cited by 1,294

Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

Ouchi, N., Kihara, S., Arita, Y., Nishida, M., Matsuyama, A., Okamoto, Y., Ishigami, M., Kuriyama, H., Kishida, K., Nishizawa, H., et al. (2001) · Circulation · doi:10.1161/01.cir.103.8.1057 · Cited by 1,281

Identification of Telmisartan as a Unique Angiotensin II Receptor Antagonist With Selective PPARγ–Modulating Activity

Benson, S. C., Pershadsingh, H. A., Ho, C. I., Chittiboyina, A. G., Desai, P. V., Pravenec, M., Qi, N., Wang, J., Avery, M. A., & Kurtz, T. W. (2004) · Hypertension · doi:10.1161/01.hyp.0000123072.34629.57 · Cited by 1,076

Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys

Hotta, K., Funahashi, T., Bodkin, N. L., Ortmeyer, H. K., Arita, Y., Hansen, B. C., & Matsuzawa, Y. (2001) · Diabetes · doi:10.2337/diabetes.50.5.1126 · Cited by 1,072

Adiponectin Reduces Atherosclerosis in Apolipoprotein E-Deficient Mice

Okamoto, Y., Kihara, S., Ouchi, N., Nishida, M., Arita, Y., Kumada, M., Ohashi, K., Sakai, N., Shimomura, I., Kobayashi, H., et al. (2002) · Circulation · doi:10.1161/01.cir.0000042707.50032.19 · Cited by 1,036

Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells

Chen, H., Montagnani, M., Funahashi, T., Shimomura, I., & Quon, M. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307878200 · Cited by 995

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms

Shibata, R., Sato, K., Pimentel, D. R., Takemura, Y., Kihara, S., Ohashi, K., Funahashi, T., Ouchi, N., & Walsh, K. (2005) · Nature Medicine · doi:10.1038/nm1295 · Cited by 982

Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty

Shimomura, I., Funahasm, T., Takahashi, M., Maeda, K., Kotani, K., Nakamura, T., Yamashita, S., Miura, M., Fukuda, Y., Takemura, K., et al. (1996) · Nature Medicine · doi:10.1038/nm0796-800 · Cited by 889

Reciprocal Association of C-Reactive Protein With Adiponectin in Blood Stream and Adipose Tissue

Ouchi, N., Kihara, S., Funahashi, T., Nakamura, T., Nishida, M., Kumada, M., Okamoto, Y., Ohashi, K., Nagaretani, H., Kishida, K., et al. (2003) · Circulation · doi:10.1161/01.cir.0000055188.83694.b3 · Cited by 853

Adiponectin as a Biomarker of the Metabolic Syndrome

Ryo, M., Nakamura, T., Kihara, S., Kumada, M., Shibazaki, S., Takahashi, M., Nagai, M., Matsuzawa, Y., & Funahashi, T. (2004) · Circulation Journal · doi:10.1253/circj.68.975 · Cited by 777

Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells

Ouchi, N., Kobayashi, H., Kihara, S., Kumada, M., Sato, K., Inoue, T., Funahashi, T., & Walsh, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310389200 · Cited by 759

Obesity, adiponectin and vascular inflammatory disease

Ouchi, N., Kihara, S., Funahashi, T., Matsuzawa, Y., & Walsh, K. X. (2003) · Current Opinion in Lipidology · doi:10.1097/00041433-200312000-00003 · Cited by 755

Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors

Iwaki, M., Matsuda, M., Maeda, N., Funahashi, T., Matsuzawa, Y., Makishima, M., & Shimomura, I. (2003) · Diabetes · doi:10.2337/diabetes.52.7.1655 · Cited by 747

Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator–Activated Receptor-γ Activity

Schupp, M., Janke, J., Clasen, R., Unger, T., & Kintscher, U. (2004) · Circulation · doi:10.1161/01.cir.0000127955.36250.65 · Cited by 707

Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell

Arita, Y., Kihara, S., Ouchi, N., Maeda, K., Kuriyama, H., Okamoto, Y., Kumada, M., Hotta, K., Nishida, M., Takahashi, M., et al. (2002) · Circulation · doi:10.1161/01.cir.0000018622.84402.ff · Cited by 698

Selective Suppression of Endothelial Cell Apoptosis by the High Molecular Weight Form of Adiponectin

Kobayashi, H., Ouchi, N., Kihara, S., Walsh, K. X., Kumada, M., Abe, Y., Funahashi, T., & Matsuzawa, Y. (2004) · Circulation Research · doi:10.1161/01.res.0000119921.86460.37 · Cited by 666

Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype

Ohashi, K., Parker, J. L., Ouchi, N., Higuchi, A., Vita, J. A., Gokce, N., Pedersen, A. A., Kalthoff, C., Tullin, S., Sams, A., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.088708 · Cited by 646

Hypoadiponectinemia Is an Independent Risk Factor for Hypertension

Iwashima, Y., Katsuya, T., Ishikawa, K., Ouchi, N., Ohishi, M., Sugimoto, K., Fu, Y., Motone, M., Yamamoto, K. I., Matsuo, A., et al. (2004) · Hypertension · doi:10.1161/01.hyp.0000129281.03801.4b · Cited by 609

Association of Hypoadiponectinemia With Impaired Vasoreactivity

Ouchi, N., Ohishi, M., Kihara, S., Funahashi, T., Nakamura, T., Nagaretani, H., Kumada, M., Ohashi, K., Okamoto, Y., Nishizawa, H., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000083488.67550.b8 · Cited by 597

Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin

Kamada, Y., Tamura, S., Kiso, S., Matsumoto, H., Saji, Y., Yoshida, Y., Fukui, K., Maeda, N., Nishizawa, H., Nagaretani, H., et al. (2003) · Gastroenterology · doi:10.1053/j.gastro.2003.08.029 · Cited by 479

Inflamed fat: what starts the fire?

Neels, J. G. (2005) · Journal of Clinical Investigation · doi:10.1172/jci27280 · Cited by 463

Association between adiponectin and mediators of inflammation in obese women

Engeli, S., Feldpausch, M., Gorzelniak, K., Hartwig, F., Heintze, U., Janke, J., Möhlig, M., Pfeiffer, A. F. H., Luft, F. C., & Sharma, A. M. (2003) · Diabetes · doi:10.2337/diabetes.52.4.942 · Cited by 422

Adiponectin Replenishment Ameliorates Obesity-Related Hypertension

Ohashi, K., Kihara, S., Ouchi, N., Kumada, M., Fujita, K., Hiuge, A., Hibuse, T., Ryo, M., Nishizawa, H., Maeda, N., et al. (2006) · Hypertension · doi:10.1161/01.hyp.0000222368.43759.a1 · Cited by 400

Decreased plasma adiponectin concentration in patients with essential hypertension

Adamczak, M. (2003) · American Journal of Hypertension · doi:10.1016/s0895-7061(02)03197-7 · Cited by 387

Association of Adiponectin Mutation With Type 2 Diabetes

Kondo, H., Shimomura, I., Matsukawa, Y., Kumada, M., Takahashi, M., Matsuda, M., Ouchi, N., Kihara, S., Kawamoto, T., Sumitsuji, S., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2325 · Cited by 386

Adiponectin modulates inflammatory reactions via calreticulin receptor–dependent clearance of early apoptotic bodies

Takemura, Y., Ouchi, N., Shibata, R., Aprahamian, T. R., Kirber, M. T., Summer, R. S., Kihara, S., & Walsh, K. X. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29709 · Cited by 369

Hypoadiponectinemia Is Associated with Impaired Endothelium-Dependent Vasodilation

Tan, K. C. B., Xu, A., Chow, W.-S., Lam, M. C., Ai, V. H. G., Tam, S., & Lam, K. S. L. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031012 · Cited by 356

Hypoadiponectinemia Is Closely Linked to Endothelial Dysfunction in Man

Shimabukuro, M., Higa, N., Asahi, T., Oshiro, Y., Takasu, N., Tagawa, T., Ueda, S., Shimomura, I., Funahashi, T., & Matsuzawa, Y. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021883 · Cited by 349

Adiponectin Stimulates Angiogenesis in Response to Tissue Ischemia through Stimulation of AMP-activated Protein Kinase Signaling

Shibata, R., Ouchi, N., Kihara, S., Sato, K., Funahashi, T., & Walsh, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402558200 · Cited by 336

Inflammatory Markers, Adiponectin, and Risk of Type 2 Diabetes in the Pima Indian

Krakoff, J. A., Funahashi, T., Stehouwer, C. D. A., Schalkwijk, C. G., Tanaka, S., Matsuzawa, Y., Kobes, S., Tataranni, P. A., Hanson, R. L., Knowler, W. C., et al. (2003) · Diabetes Care · doi:10.2337/diacare.26.6.1745 · Cited by 330

Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells

Cheng, K. K. Y., Lam, K. S. L., Wang, Y., Huang, Y., Carling, D., Wu, D., Wong, C., & Xu, A. (2007) · Diabetes · doi:10.2337/db06-1580 · Cited by 318

Young Men With High-Normal Blood Pressure Have Lower Serum Adiponectin, Smaller LDL Size, and Higher Elevated Heart Rate Than Those With Optimal Blood Pressure

Kazumi, T., Kawaguchi, A. T., Sakai, K., Hirano, T., & Yoshino, G. (2002) · Diabetes Care · doi:10.2337/diacare.25.6.971 · Cited by 274

Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo

Ouedraogo, R., Gong, Y., Berzins, B., Wu, X., Mahadev, K., Hough, K., Chan, L., Goldstein, B. J., & Scalia, R. G. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29623 · Cited by 265

Hypoadiponectinemia as a Predictor for the Development of Hypertension

Chow, W.-S., Cheung, B. M. Y., Tso, A. W. K., Xu, A., Wat, N. M. S., Fong, C. H.-Y., Ong, L. H. Y., Tam, S., Tan, K. C. B., Janus, E. D., et al. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.086835 · Cited by 262

Adiponectin inhibits Toll‐like receptor family‐induced signaling

Yamaguchi, N., Argueta, J. G. M., Masuhiro, Y., Kagishita, M., Nonaka, K., Saito, T., Hanazawa, S., & Yamashita, Y. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.11.019 · Cited by 259

Globular adiponectin upregulates nitric oxide production in vascular endothelial cells

Hattori, Y., Suzuki, M., Hattori, S., & Kasai, K. (2003) · Diabetologia · doi:10.1007/s00125-003-1224-3 · Cited by 210

Adiponectin Inhibits the Production of CXC Receptor 3 Chemokine Ligands in Macrophages and Reduces T-Lymphocyte Recruitment in Atherogenesis

Okamoto, Y., Folco, E. J. E., Minami, M., Wara, A. K., Feinberg, M. W., Sukhova, G. K., Colvin, R. A., Kihara, S., Funahashi, T., Luster, A. D., et al. (2007) · Circulation Research · doi:10.1161/circresaha.107.164988 · Cited by 208

Adiponectin Prevents Cerebral Ischemic Injury Through Endothelial Nitric Oxide Synthase–Dependent Mechanisms

Nishimura, M., Izumiya, Y., Higuchi, A., Shibata, R., Qiu, J., Kudo, C., Shin, H. K., Moskowitz, M. A., & Ouchi, N. (2007) · Circulation · doi:10.1161/circulationaha.107.725044 · Cited by 207

Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease

Ohashi, K., Ouchi, N., Kihara, S., Funahashi, T., Nakamura, T., Sumitsuji, S., Kawamoto, T., Matsumoto, S., Nagaretani, H., Kumada, M., et al. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.10.049 · Cited by 203

Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation

Kurata, A., Nishizawa, H., Kihara, S., Maeda, N., Sonoda, M., Okada, T., Ohashi, K., Hibuse, T., Fujita, K., Yasui, A., et al. (2006) · Kidney International · doi:10.1038/sj.ki.5001810 · Cited by 166

Effects of Selective Cyclooxygenase-2 Inhibition on Vascular Responses and Thrombosis in Canine Coronary Arteries

Hennan, J. K., Huang, J., Barrett, T. D., Driscoll, E. M., Willens, D. E., Park, A. M., Crofford, L. J., & Lucchesi, B. R. (2001) · Circulation · doi:10.1161/hc3301.092790 · Cited by 163

Effects of valsartan compared to amlodipine on preventing type 2 diabetes in high-risk hypertensive patients: the VALUE trial

Kjeldsen, S. E., Julius, S., Mancia, G., McInnes, G. T., Hua, T. A., Weber, M. A., Coca, A., Ekman, S., Girerd, X. J., Jamerson, K., et al. (2006) · Journal of Hypertension · doi:10.1097/01.hjh.0000234122.55895.5b · Cited by 161

Serum adiponectin concentrations predict the developments of type 2 diabetes and the metabolic syndrome in elderly Koreans

Choi, K. M., Lee, J., Lee, K. W., Seo, J. A., Oh, J.-H., Kim, S. G., Kim, N. H., Choi, D. S., & Baik, S. H. (2004) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2004.02063.x · Cited by 153

Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance

Ran, J., Hirano, T., Fukui, T., Saito, K., Kageyama, H., Okada, K., & Adachi, M. (2006) · Metabolism · doi:10.1016/j.metabol.2005.10.009 · Cited by 140

The Endothelium and Cardiovascular Disease -- A Complex Relation

Lüscher, T. F. (1994) · New England Journal of Medicine · doi:10.1056/nejm199404143301511 · Cited by 132

Caloric Restriction Stimulates Revascularization in Response to Ischemia via Adiponectin-mediated Activation of Endothelial Nitric-oxide Synthase

Kondo, M., Shibata, R., Miura, R., Shimano, M., Kondo, K., Li, P., Ohashi, T., Kihara, S., Maeda, N., Walsh, K., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m805301200 · Cited by 124

Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes

Bodles, A. M., Banga, A., Rasouli, N., Ono, F., Kern, P. A., & Owens, R. J. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00187.2006 · Cited by 122

Adiponectin Deficiency, Diastolic Dysfunction, and Diastolic Heart Failure

Sam, F., Duhaney, T.-A. S., Sato, K., Wilson, R. M., Ohashi, K., Sono-Romanelli, S., Higuchi, A., Silva, D. S. D., Qin, F., Walsh, K., et al. (2009) · Endocrinology · doi:10.1210/en.2009-0806 · Cited by 90

Adiponectin Promotes Revascularization of Ischemic Muscle through a Cyclooxygenase 2-Dependent Mechanism

Ohashi, K., Ouchi, N., Sato, K., Higuchi, A., Ishikawa, T., Herschman, H. R., Kihara, S., & Walsh, K. X. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00126-09 · Cited by 83

Adiponectin Suppresses Pathological Microvessel Formation in Retina Through Modulation of Tumor Necrosis Factor-α Expression

Higuchi, A., Ohashi, K., Kihara, S., Walsh, K., & Ouchi, N. (2009) · Circulation Research · doi:10.1161/circresaha.109.194506 · Cited by 76

Disturbed secretion of mutant adiponectin associated with the metabolic syndrome

Kishida, K., Nagaretani, H., Kondo, H., Kobayashi, H., Tanaka, S., Maeda, N., Nagasawa, A., Hibuse, T., Ohashi, K., Kumada, M., et al. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00940-9 · Cited by 72

The effects of irbesartan and telmisartan on metabolic parameters and blood pressure in obese, insulin resistant, hypertensive patients

Negro, R., Formoso, G., & Hassan, H. (2006) · Journal of Endocrinological Investigation · doi:10.1007/bf03349207 · Cited by 67

Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension

Bulut, D., Liaghat, S., Hanefeld, C., Koll, R., Miebach, T., & gge, A. M. U. (2003) · Journal of Hypertension · doi:10.1097/00004872-200309000-00015 · Cited by 65

Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial nitric oxide synthase and nitric oxide-mediated endothelial function in human atherosclerosis

Guzik, T. J., Black, E., West, N. E. J., McDonald, D., Ratnatunga, C., Pillai, R. G., & Channon, K. M. (2001) · American Journal of Medical Genetics · doi:10.1002/ajmg.1229 · Cited by 60

Adiponectin secretion and response to pioglitazone is depot dependent in cultured human adipose tissue

Phillips, S. A., Ciaraldi, T. P., Oh, D. K., Savu, M. K., & Henry, R. R. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90359.2008 · Cited by 60

Role of Adiponectin in Insulin-Resistant Hypertension and Atherosclerosis

MURAKAMI, H., Ura, N., Furuhashi, M., Higashiura, K., Miura, T., & Shimamoto, K. (2003) · Hypertension Research · doi:10.1291/hypres.26.705 · Cited by 53

Angiotensin II Receptor Blocker Inhibits Neointimal Hyperplasia Through Regulation of Smooth Muscle–Like Progenitor Cells

Yamada, T., Kondo, T., Numaguchi, Y., Tsuzuki, M., Matsubara, T., Manabe, I., Sata, M., Nagai, R., & Murohara, T. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.147124 · Cited by 51

Peroxisome Proliferator-Activated Receptor-γ Increases Adiponectin Secretion via Transcriptional Repression of Endoplasmic Reticulum Chaperone Protein ERp44

Long, Q., Lei, T., Feng, B., Yin, C., Jin, D., Wu, Y., Zhu, X. A., Chen, X., Gan, L., & Yang, Z. (2010) · Endocrinology · doi:10.1210/en.2009-1501 · Cited by 50

The effect of losartan and amlodipine on serum adiponectin in Japanese adults with essential hypertension

Watanabe, S., Okura, T., Kurata, M., Irita, J., Manabe, S., Miyoshi, K., Fukuoka, T., Murakami, K., & Higaki, J. (2006) · Clinical Therapeutics · doi:10.1016/j.clinthera.2006.10.012 · Cited by 49

COX-2 contributes to the maintenance of flow-induced dilation in arterioles of eNOS-knockout mice

Sun, D., Liu, H., Yan, C., Jacobson, A., Ojaimi, C., Huang, A., & Kaley, G. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01130.2005 · Cited by 48

Effects of ARB or ACE-Inhibitor Administration on Plasma Levels of Aldosterone and Adiponectin in Hypertension

Nakamura, T., Kawachi, K., Saito, Y., Saito, T., Morishita, K., Hoshino, J., Hosoi, T., Iwasaki, T., Ohyama, Y., & Kurabayashi, M. (2009) · International Heart Journal · doi:10.1536/ihj.50.501 · Cited by 46

Vascular signaling pathways in the metabolic syndrome

Rakugi, H., Kamide, K., & Ogihara, T. (2002) · Current Hypertension Reports · doi:10.1007/s11906-002-0034-1 · Cited by 25

Effects of losartan on serum total and high–molecular weight adiponectin concentrations in hypertensive patients with metabolic syndrome

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