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MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression
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PI(4,5)P2 may modulate LDLR through its effect on LDLR lysosomal decay.
“Inhibition of lysosome activity increases cell surface LDLRs10, suggesting that PI(4,5)P2 may modulate LDLR through its effect on LDLR lysosomal decay.”
From Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation (2020) · cites this paper as [10]
Inhibition of lysosome activity increases cell surface LDLRs.
“Inhibition of lysosome activity increases cell surface LDLRs10, suggesting that PI(4,5)P2 may modulate LDLR through its effect on LDLR lysosomal decay.”
From Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation (2020) · cites this paper as [10]
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Cites
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Cited by
Sorted by citations
Qin, Y., Ting, F., Kim, M. J., Strelnikov, J., Harmon, J., Gao, F., Dose, A., Teng, B.-B., Alipour, M. A., Yao, Z., et al. (2020) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.120.314033 · Cited by 18
Self-citation
Metadata
- Authors
- Yan, H., Ma, Y.-L., Gui, Y.-Z., Wang, S.-M., Wang, X.-B., Gao, F., & Wang, Y.-P.
- Venue
- Acta Pharmacologica Sinica
- Published
- 2014-07-21
- Volume
- 35
- Issue
- 8
- Pages
- 994-1004
- ISSN
- 1671-4083
- 1745-7254
- Cited by
- 35
- References
- 1
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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