The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
The mechanism of photodynamic inactivation of human cells in vitro in the presence of haematoporphyrin
Open accessAbstract
The photosensitizing effect of haematoporphyrin (HP) on human cells of the established line NHIK 3025 has been studied. Fluorescence measurements show that HP is bound to these cells. Serum proteins also bind HP, and the presence of 10% human serum during incubation with HP (3 X 10(-4)M) reduces the cellular uptake of HP by 75% or more. The photosensitized inactivation is enhanced when the cells are suspended in D2O-buffer during irradiation. This indicates that singlet oxygen is involved in the inactivation. Two findings indicate that the photoinduced damage is repairable: firstly, the fraction of cells surviving a given light dose decreases with decreasing irradiation temperature, and secondly, the survival curves have a shoulder at low exposures of light.
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Citations
Cites
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Cellular Responses to Combinations of Hyperthermia and Radiation
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Role of Lysosomes and of Cell Membranes in Photosensitization
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Tannock, I. F. (1972) · The British Journal of Radiology · doi:10.1259/0007-1285-45-535-515 · Cited by 264
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Cited by
Dougherty, T. J., Gomer, C. J., Henderson, B. W., Jori, G., Kessel, D., Korbelik, M., Moan, J., & Peng, Q. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.12.889 · Cited by 4,716
Self-citationTwo-Photon Photodynamic Therapy
BHAWALKAR, J. D., KUMAR, N. D., ZHAO, C.-F., & PRASAD, P. N. (1997) · Journal of Clinical Laser Medicine & Surgery · doi:10.1089/clm.1997.15.201 · Cited by 543
Porphyrin‐related photosensitizers for cancer imaging and therapeutic applications
BERG, K., SELBO, P. K., WEYERGANG, A., DIETZE, A., PRASMICKAITE, L., BONSTED, A., ENGESAETER, B. Ø., ANGELL‐PETERSEN, E., WARLOE, T., FRANDSEN, N., et al. (2005) · Journal of Microscopy · doi:10.1111/j.1365-2818.2005.01471.x · Cited by 274
Apoptosis and necrosis induced with light and 5-aminolaevulinic acid-derived protoporphyrin IX
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The influence of temperature on photodynamic cell killing in vitro with 5-aminolevulinic acid
Juzeniene, A., Juzenas, P., Bronshtein, I., Vorobey, A., & Moan, J. (2006) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/j.jphotobiol.2006.02.009 · Cited by 41
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Metadata
- Authors
- Moan, J., Pettersen, E. O., & Christensen, T.
- Venue
- British Journal of Cancer
- Published
- 1979-04
- Volume
- 39
- Issue
- 4
- Pages
- 398-407
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- OpenAlex
- W1981951234
- Cited by
- 270
- References
- 17
- FWCI
- 21.07
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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