Photodynamic Therapy

Photodynamic therapy with endogenous protoporphyrin

Kennedy, J. C., Pottier, R. H., & Pross, D. C. (1990) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(90)85083-9 · Cited by 1,509 · see citing works

5-Aminolevulinic Acid-Based Photodynamic Therapy: Principles and Experimental Research

Peng, Q., Berg, K., Moan, J., Kongshaug, M., & Nesland, J. M. (1997) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1997.tb08549.x · Cited by 615 · see citing works

Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid

Kriegmair, M., Ehsan, A., Baumgartner, R., Lumper, W., Knuechel, R., Hofstädter, F., Steinbach, P., & Hofstetter, A. (1994) · Urology · doi:10.1016/s0090-4295(94)80167-3 · Cited by 265 · see citing works

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

Zorov, D. B., Juhaszova, M., & Sollott, S. J. (2014) · Physiological Reviews · doi:10.1152/physrev.00026.2013 · Cited by 5,383 · see citing works

Oxidative Stress

Sies, H., Berndt, C., & Jones, D. P. (2017) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-061516-045037 · Cited by 3,520 · see citing works

Porphyrin and Nonporphyrin Photosensitizers in Oncology: Preclinical and Clinical Advances in Photodynamic Therapy

O’Connor, A. E., Gallagher, W. M., & Byrne, A. T. (2009) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2009.00585.x · Cited by 1,191 · see citing works

Photosensitizers with Aggregation‐Induced Emission: Materials and Biomedical Applications

Hu, F., Xu, S., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201801350 · Cited by 859 · see citing works

Enhanced Permeability and Retention (EPR) Effect for Anticancer Nanomedicine Drug Targeting

Greish, K. (2010) · Methods in Molecular Biology · doi:10.1007/978-1-60761-609-2_3 · Cited by 841 · see citing works

Light Sources and Dosimetry Techniques for Photodynamic Therapy

Kim, M. M., & Darafsheh, A. (2020) · Photochemistry and Photobiology · doi:10.1111/php.13219 · Cited by 454 · see citing works

Photodynamic Therapy for the Treatment and Diagnosis of Cancer–A Review of the Current Clinical Status

Gunaydin, G., Gedik, M. E., & Ayan, S. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.686303 · Cited by 402 · see citing works

A review of <i>in‐vivo</i> optical properties of human tissues and its impact on PDT

Sandell, J. L., & Zhu, T. C. (2011) · Journal of Biophotonics · doi:10.1002/jbio.201100062 · Cited by 384 · see citing works

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer

Wachowska, M., Muchowicz, A., Firczuk, M., Gabrysiak, M., Winiarska, M., Wańczyk, M., Bojarczuk, K., & Golab, J. (2011) · Molecules · doi:10.3390/molecules16054140 · Cited by 265 · see citing works

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Ojha, T., Pathak, V., Shi, Y., Hennink, W. E., Moonen, C. T. W., Storm, G., Kiessling, F., & Lammers, T. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.07.007 · Cited by 260 · see citing works

Polymeric micelles: authoritative aspects for drug delivery

Kulthe, S. S., Choudhari, Y. M., Inamdar, N. N., & Mourya, V. (2012) · Designed Monomers and Polymers · doi:10.1080/1385772x.2012.688328 · Cited by 235 · see citing works

Time‐Dependent Photodynamic Therapy for Multiple Targets: A Highly Efficient AIE‐Active Photosensitizer for Selective Bacterial Elimination and Cancer Cell Ablation

Li, Q., Li, Y., Min, T., Gong, J., Du, L., Phillips, D. L., Liu, J., Lam, J. W. Y., Sung, H. H. Y., Williams, I. D., et al. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201909706 · Cited by 211 · see citing works

DNA damage by singlet oxygen and cellular protective mechanisms

Agnez-Lima, L. F., Melo, J. T. A., Silva, A. E., Oliveira, A. H. S., Timoteo, A. R. S., Lima-Bessa, K. M., Martinez, G. R., Medeiros, M. H. G., Di Mascio, P., Galhardo, R. S., et al. (2012) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2011.12.005 · Cited by 205 · see citing works

Mechanisms involved in δ-aminolevulinic acid (ALA)-induced photosensitivity of tumor cells: Relation of ferrochelatase and uptake of ALA to the accumulation of protoporphyrin

Ohgari, Y., Nakayasu, Y., Kitajima, S., Sawamoto, M., Mori, H., Shimokawa, O., Matsui, H., & Taketani, S. (2005) · Biochemical Pharmacology · doi:10.1016/j.bcp.2005.10.019 · Cited by 165 · see citing works

Photodynamic antimicrobial chemotherapy (PACT) with methylene blue increases membrane permeability in Candida albicans

Giroldo, L. M., Felipe, M. P., de Oliveira, M. A., Munin, E., Alves, L. P., & Costa, M. S. (2009) · Lasers in Medical Science · doi:10.1007/s10103-007-0530-2 · Cited by 151 · see citing works

Daylight Photodynamic Therapy: An Update

Lee, C.-N., Hsu, R., Chen, H., & Wong, T.-W. (2020) · Molecules · doi:10.3390/molecules25215195 · Cited by 143 · see citing works

The Tyrosine Kinase Inhibitor Imatinib Mesylate Enhances the Efficacy of Photodynamic Therapy by Inhibiting ABCG2

Liu, W., Baer, M. R., Bowman, M. J., Pera, P., Zheng, X., Morgan, J., Pandey, R. A., & Oseroff, A. R. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-1599 · Cited by 136 · see citing works

Improvement of Tumor Response by Manipulation of Tumor Oxygenation During Photodynamic Therapy¶

Chen, Q., Huang, Z., Chen, H., Shapiro, H., Beckers, J., & Hetzel, F. W. (2007) · Photochemistry and Photobiology · doi:10.1562/0031-8655(2002)0760197iotrbm2.0.co2 · Cited by 124 · see citing works

Porphyrin formation in actinic keratosis and basal cell carcinoma after topical application of methyl 5-aminolevulinate

Angell-Petersen, E., Sørensen, R., Warloe, T., Soler, A. M., Moan, J., Peng, Q., & Giercksky, K.-E. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700048 · Cited by 123 · see citing works

Hypoxia signaling in cancer: Implications for therapeutic interventions

Zhuang, Y., Liu, K., He, Q., Gu, X., Jiang, C., & Wu, J. (2023) · MedComm · doi:10.1002/mco2.203 · Cited by 119 · see citing works

Mitochondrial and Endoplasmic Reticulum Stress-Induced Apoptotic Pathways Are Activated by 5-Aminolevulinic Acid-Based Photodynamic Therapy in HL60 Leukemia Cells

Grebeňová, D., Kuželová, K., Smetana, K., Pluskalová, M., Cajthamlová, H., Marinov, I., Fuchs, O., Souček, J., Jarolı́m, P., & Hrkal, Z. (2003) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/s1011-1344(02)00410-4 · Cited by 107 · see citing works

Manipulating exciton dynamics of thermally activated delayed fluorescence materials for tuning two-photon nanotheranostics

Xiao, Y.-F., Chen, J.-X., Li, S., Tao, W.-W., Tian, S., Wang, K., Cui, X., Huang, Z., Zhang, X.-H., & Lee, C.-S. (2020) · Chemical Science · doi:10.1039/c9sc05817f · Cited by 84 · see citing works

Involvement of both caspase-dependent and -independent pathways in apoptotic induction by hexaminolevulinate-mediated photodynamic therapy in human lymphoma cells

Furre, I. E., Møller, M. T. N., Shahzidi, S., Nesland, J. M., & Peng, Q. (2006) · Apoptosis · doi:10.1007/s10495-006-0190-x · Cited by 66 · see citing works

Hyperresistance to photosensitized lipid peroxidation and apoptotic killing in 5-aminolevulinate-treated tumor cells overexpressing mitochondrial GPX4

Kriska, T., Korytowski, W., & Girotti, A. W. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01078-x · Cited by 59 · see citing works

Recent advances in <i>in situ</i> oxygen-generating and oxygen-replenishing strategies for hypoxic-enhanced photodynamic therapy

Qin, S., Xu, Y., Li, H., Chen, H., & Yuan, Z. (2022) · Biomaterials Science · doi:10.1039/d1bm00317h · Cited by 56 · see citing works

Massive Apoptotic Cell Death of Human Glioma Cells via a Mitochondrial Pathway Following 5-Aminolevulinic Acid-Mediated Photodynamic Therapy

Inoue, H., Kajimoto, Y., Shibata, M.-A., Miyoshi, N., Ogawa, N., Miyatake, S.-I., Otsuki, Y., & Kuroiwa, T. (2007) · Journal of Neuro-Oncology · doi:10.1007/s11060-006-9325-8 · Cited by 50 · see citing works

Antagonistic Effects of Endogenous Nitric Oxide in a Glioblastoma Photodynamic Therapy Model

Fahey, J. M., Emmer, J. V., Korytowski, W., Hogg, N., & Girotti, A. W. (2016) · Photochemistry and Photobiology · doi:10.1111/php.12636 · Cited by 49 · see citing works

Electrospun polyacrylonitrile nanofibers modified by quaternary ammonium salts

Gliścińska, E., Gutarowska, B., Brycki, B., & Krucińska, I. (2013) · Journal of Applied Polymer Science · doi:10.1002/app.38210 · Cited by 42 · see citing works

RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT: RIP3 IN PDT-INDUCED CELL DEATH

Coupienne, I., Fettweis, G., & Piette, J. (2011) · Lasers in Surgery and Medicine · doi:10.1002/lsm.21088 · Cited by 41 · see citing works

Differential Sensitivity in Cell Lines to Photodynamic Therapy in Combination with ABCG2 Inhibition

Barron, G. A., Moseley, H., & Woods, J. A. (2013) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/j.jphotobiol.2013.07.003 · Cited by 40 · see citing works

Photodynamic therapy of lung cancer, where are we?

Crous, A., & Abrahamse, H. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.932098 · Cited by 38 · see citing works

Upstream signaling events leading to elevated production of pro-survival nitric oxide in photodynamically-challenged glioblastoma cells

Fahey, J. M., Korytowski, W., & Girotti, A. W. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.04.013 · Cited by 38 · see citing works

Topical aminolaevulinic acid-photodynamic therapy produces an inflammatory infiltrate but reduces Langerhans cells in healthy human skin in vivo: ALA-PDT reduces Langerhans cells in healthy skin

Evangelou, G., Farrar, M. D., White, R. D., Sorefan, N. B., Wright, K. P., McLean, K., Andrew, S., Watson, R. E. B., & Rhodes, L. E. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10433.x · Cited by 27 · see citing works

Advances on fluorescence bioimaging and photo-mediated therapy of NIR-II small molecule dyes

Zhang, W., Laraib, Huo, F., & Yin, C. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216587 · Cited by 26 · see citing works

ALA-PDT elicits oxidative damage and apoptosis in UVB-induced premature senescence of human skin fibroblasts

Zhou, B.-R., Zhang, L.-C., Permatasari, F., Liu, J., Xu, Y., & Luo, D. (2016) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2016.02.005 · Cited by 23 · see citing works

Potentiating effect of beta-glucans on photodynamic therapy of implanted cancer cells in mice

Akramiene, D., Aleksandraviciene, C., Grazeliene, G., Zalinkevicius, R., Suziedelis, K., Didziapetriene, J., Simonsen, U., Stankevicius, E., & Kevelaitis, E. (2010) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.220.299 · Cited by 17 · see citing works

Iron chelation promotes 5-aminolaevulinic acid-based photodynamic therapy against oral tongue squamous cell carcinoma

Qin, J., Zhou, C., Zhu, M., Shi, S., Zhang, L., Zhao, Y., Li, C., Wang, Y., & Wang, Y. (2020) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2020.101907 · Cited by 17 · see citing works

Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis

Darvekar, S., Juzenas, P., Oksvold, M., Kleinauskas, A., Holien, T., Christensen, E., Stokke, T., Sioud, M., & Peng, Q. (2020) · Cancers · doi:10.3390/cancers12020377 · Cited by 16 · see citing works

The effect of photodynamic therapy on rat urinary bladder with orthotopic urothelial carcinoma

Grönlund‐Pakkanen, S., Wahlfors, J., Talja, M., Kosma, V. ‐., Pakkanen, T. M., Ala‐Opas, M., Alhava, E., & Moore, R. B. (2003) · BJU International · doi:10.1046/j.1464-410x.2003.04290.x · Cited by 14 · see citing works