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Confirmation of a prognostic index in primary breast cancer
Open accessAbstract
A prognostic index, previously derived in a group of 387 patients with primary breast cancer, has been recalculated for the same patients with over 5 years further follow-up and shown to be unchanged. The prognostic index has also been applied prospectively to a further group of 320 patients and shown to be similarly effective in identifying patients with either a very good or a very poor prognosis. It has been verified that the index applies to patients with primary breast cancer. Patients have now been divided into 5 prognostic groups, predicting 11% of patients with an almost normal survival and a further 10% with a very poor prognosis. The index is used to stratify patients to study the effects of treatment regimes within groups of similar patients.
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Citations
Cited by
Pathological prognostic factors in breast cancer
Elston, C. (1999) · Critical Reviews in Oncology/Hematology · doi:10.1016/s1040-8428(99)00034-7 · Cited by 1,735
Self-citationBuyse, M., Loi, S., van't Veer, L., Viale, G., Delorenzi, M., Glas, A. M., Saghatchian d'Assignies, M., Bergh, J., Lidereau, R., Ellis, P., et al. (2006) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/djj329 · Cited by 1,238
The Nottingham prognostic index in primary breast cancer
Galea, M. H., Blamey, R. W., Elston, C. E., & Ellis, I. O. (1992) · Breast Cancer Research and Treatment · doi:10.1007/bf01840834 · Cited by 1,070
Self-citationGevaert, O., Smet, F. D., Timmerman, D., Moreau, Y., & Moor, B. D. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl230 · Cited by 351
Methodological challenges in the evaluation of prognostic factors in breast cancer.
Altman, D. G., & Lyman, G. H. (1998) · Breast Cancer Research and Treatment · doi:10.1023/a:1006193704132 · Cited by 271
Metadata
- Authors
- Todd, J., Dowle, C., Williams, M., Elston, C., Ellis, I., Hinton, C., Blamey, R., & Haybittle, J.
- Venue
- British Journal of Cancer
- Published
- 1987-12
- Volume
- 56
- Issue
- 4
- Pages
- 489-492
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- OpenAlex
- W1974963731
- Cited by
- 308
- References
- 0
- FWCI
- 4.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Todd, J., Dowle, C., Williams, M., Elston, C., Ellis, I., Hinton, C., Blamey, R., & Haybittle, J. (1987). Confirmation of a prognostic index in primary breast cancer. British Journal of Cancer. https://doi.org/10.1038/bjc.1987.230
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