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Cited by 384

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis

Open access
Rodriguez, D A, Weinlich, R, Brown, S, Guy, C, Fitzgerald, P, Dillon, C P, Oberst, A, Quarato, G, Low, J, Cripps, J G, Chen, T, Green, D R·2016·Cell Death & Differentiation

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Crossref · 10.1038/cdd.2015.70

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Citations

Cites

1 retracted

Show all 14 references

Research works printed but not linked: 26

  1. Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J et al. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci USA 2012; 109: 5322–5327. · DOI · Paper page
  2. Sun L, Wang H, Wang Z, He S, Chen S, Liao D et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012; 148: 213–227. · DOI · Paper page
  3. Green DR, Oberst A, Dillon CP, Weinlich R, Salvesen GS . RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol Cell 2011; 44: 9–16. · DOI · Paper page
  4. Zhang H, Zhou X, McQuade T, Li J, Chan FK, Zhang J . Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 2011; 471: 373–376. · DOI · Paper page
  5. Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T et al. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 2014; 157: 1175–1188. · DOI · Paper page
  6. Weinlich R, Green DR . The two faces of receptor interacting protein kinase-1. Mol Cell 2014; 56: 469–480. · DOI
  7. Chen X, Li W, Ren J, Huang D, He WT, Song Y et al. Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death. Cell Res 2014; 24: 105–121. · DOI · Paper page
  8. Wang H, Sun L, Su L, Rizo J, Liu L, Wang LF et al. Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. Mol Cell 2014; 54: 133–146. · DOI · Paper page
  9. Dondelinger Y, Declercq W, Montessuit S, Roelandt R, Goncalves A, Bruggeman I et al. MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates. Cell Rep 2014; 7: 971–981. · DOI · Paper page
  10. Xie T, Peng W, Yan C, Wu J, Gong X, Shi Y . Structural insights into RIP3-mediated necroptotic signaling. Cell Rep 2013; 5: 70–78. · DOI · Paper page
  11. Green DR . Pseudokiller, qu'est-ce que c'est? Immunity 2013; 39: 421–422. · DOI
  12. Weinert BT, Scholz C, Wagner SA, Iesmantavicius V, Su D, Daniel JA et al. Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Rep 2013; 4: 842–851. · DOI · Paper page
  13. Verdin E, Ott M . 50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond. Nat Rev Mol Cell Biol 2014; 16: 258–264. · DOI · Paper page
  14. Orozco S, Yatim N, Werner MR, Tran H, Gunja SY, Tait SW et al. RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis. Cell Death Differ 2014; 21: 1511–1521. · DOI · Paper page
  15. Thapa RJ, Nogusa S, Chen P, Maki JL, Lerro A, Andrake M et al. Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases. Proc Natl Acad Sci USA 2013; 110: E3109–E3118. · DOI · Paper page
  16. Li JX, Feng JM, Wang Y, Li XH, Chen XX, Su Y et al. The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. Cell Death Dis 2014; 5: e1278. · DOI · Paper page
  17. Wu XN, Yang ZH, Wang XK, Zhang Y, Wan H, Song Y et al. Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis. Cell Death Differ 2014; 21: 1709–1720. · DOI · Paper page
  18. Chen W, Zhou Z, Li L, Zhong CQ, Zheng X, Wu X et al. Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. J Biol Chem 2013; 288: 16247–16261. · DOI · Paper page
  19. Dondelinger Y, Aguileta MA, Goossens V, Dubuisson C, Grootjans S, Dejardin E et al. RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition. Cell Death Differ 2013; 20: 1381–1392. · DOI · Paper page
  20. Tenev T, Bianchi K, Darding M, Broemer M, Langlais C, Wallberg F et al. The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 2011; 43: 432–448. · DOI · Paper page
  21. Remijsen Q, Goossens V, Grootjans S, Van den Haute C, Vanlangenakker N, Dondelinger Y et al. Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis. Cell Death Dis 2014; 5: e1004. · DOI · Paper page
  22. Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell 2014; 56: 481–495. · DOI · Paper page
  23. Cook WD, Moujalled DM, Ralph TJ, Lock P, Young SN, Murphy JM et al. RIPK1- and RIPK3-induced cell death mode is determined by target availability. Cell Death Differ 2014; 21: 1600–1612. · DOI
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  25. Kyung Kim S, Kim WJ, Yoon JH, Ji JH, Morgan MJ, Cho H et al. Upregulated RIP3 expression potentiates MLKL phosphorylation-mediated programmed necrosis in toxic epidermal necrolysis. J Invest Dermatol 2015 e-pub ahead of print 2 April 2015. · DOI
  26. Vitner EB, Salomon R, Farfel-Becker T, Meshcheriakova A, Ali M, Klein AD et al. RIPK3 as a potential therapeutic target for Gaucher's disease. Nat Med 2014; 20: 204–208. · DOI · Paper page

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Metadata

Authors
Rodriguez, D. A., Weinlich, R., Brown, S., Guy, C., Fitzgerald, P., Dillon, C. P., Oberst, A., Quarato, G., Low, J., Cripps, J. G., Chen, T., & Green, D. R.
Venue
Cell Death & Differentiation
Published
2015-05-29
Volume
23
Issue
1
Pages
76-88
ISSN
  • 1350-9047 (ISSN-L)
  • 1476-5403
OpenAlex
W1537667127
Cited by
384
References
14
FWCI
12.99
Type
journal article
Language
en
Open access
bronze
Licence
www.springer.com/tdm (tdm)

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CoChat. (2026). Citation check: Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis. https://app.cochat.ai/papers/10.1038/cdd.2015.70
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Rodriguez, D. A., Weinlich, R., Brown, S., Guy, C., Fitzgerald, P., Dillon, C. P., Oberst, A., Quarato, G., Low, J., Cripps, J. G., Chen, T., & Green, D. R. (2016). Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis. Cell Death & Differentiation. https://doi.org/10.1038/cdd.2015.70

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