BCL-2 family proteins: changing partners in the dance towards death

Kale, Justin, Osterlund, Elizabeth J, Andrews, David W·2018·Cell Death & Differentiation

DOI 10.1038/cdd.2017.186

Cited by (1,000)

Items 201–300 of 1,000

Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors
Darren C. Phillips, F. Gregory Buchanan, Dong Cheng, Larry R. Solomon, Xiao Hong Yu, John Xue, Stephen K. Tahir, Morey L. Smith, Haichao Zhang, Deborah L. Widomski et al. · 2021 · Cancer Research
Targeting the Intrinsic Apoptosis Pathway: A Window of Opportunity for Prostate Cancer
Daniel Westaby, Juan M. Jiménez‐Vacas, Ana Padilha, Andreas S. Varkaris, Steven P. Balk, Johann Sebastian De Bono, Adam Sharp · 2021 · Cancers
Branching out in different directions: Emerging cellular functions for the Arp2/3 complex and WASP-family actin nucleation factors
Campellone, Kenneth G., Lebek, Nadine M., King, Virginia L. · 2023 · European Journal of Cell Biology
Dapagliflozin ameliorates sepsis-induced heart injury by inhibiting cardiomyocyte apoptosis and electrical remodeling through the PI3K/Akt pathway
Xueyu Han, Xin Liu, Xin Zhao, Xiukun Wang, Yazhou Sun, Chuan Qu, Jinjun Liang, Bo Yang · 2023 · European Journal of Pharmacology
Comprehensive review of Bcl‐2 family proteins in cancer apoptosis: Therapeutic strategies and promising updates of natural bioactive compounds and small molecules
Iksen Iksen, Wasita Witayateeraporn, Besse Hardianti, Varisa Pongrakhananon · 2024 · Phytotherapy Research
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease
Wenyu Jiao, Yongchen Wang, Linghong Kong, Tao Ou-yang, Meng Qing, Qiang Fu, Zhenzhen Hu · 2018 · Biochemical and Biophysical Research Communications
The p53 inactivators pifithrin-μ and pifithrin-α mitigate TBI-induced neuronal damage through regulation of oxidative stress, neuroinflammation, autophagy and mitophagy
Ling-Yu Yang, Nigel H. Greig, David Tweedie, Yoo Jin Jung, Yung Hsiao Chiang, Barry J. Hoffer, Jonathan P. Miller, Ke-Hui Chang, Jia‐Yi Wang · 2019 · Experimental Neurology
Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production
Matthew N. Henry, Michael A. MacDonald, Camila A. Orellana, Peter P. Gray, Marianne Gillard, Kym N. Baker, Lars Keld Nielsen, Esteban Marcellin, Stephen M. Mahler, Verónica S. Martínez · 2020 · Biotechnology and Bioengineering
Bcl-2 on the brink of breakthroughs in cancer treatment
John C. Reed · 2017 · Cell Death and Differentiation
The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells
Xiaoke Chi, Dang Quan Nguyen, James M. Pemberton, Elizabeth J. Osterlund, Qian Liu, Hetal Brahmbhatt, Zhi Zhang, Jialing Lin, Brian F. Leber, David William Andrews · 2020 · eLife
BH3 mimetics as anti-fibrotic therapy: Unleashing the mitochondrial pathway of apoptosis in myofibroblasts
Tobias Kühl, David Lagares · 2018 · Matrix Biology
Molecular evolution of peptides by yeast surface display technology
Sara Linciano, Stefano Pluda, Arianna Bacchin, Alessandro Angelini · 2019 · MedChemComm
Advances and Perspectives in the Treatment of T-PLL
Till Braun, Jana von Jan, Linus Wahnschaffe, Marco Herling · 2020 · Current Hematologic Malignancy Reports
MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex
Tirta Mario Djajawi, Lei Liu, Jianan Gong, Allan Shuai Huang, Mingjie Luo, Zhen Xu, Toru Okamoto, Melissa Joy Call, David C.S. Huang, Mark F. van Delft · 2020 · Cell Death and Differentiation
Reinventing the Penumbra — the Emerging Clockwork of a Multi-modal Mechanistic Paradigm
Jakob Walther, Elena Marie Kirsch, Lina Hellwig, Sarah S. Schmerbeck, Paul M. Holloway, Alastair Mitchell Buchan, Philipp Mergenthaler · 2022 · Translational Stroke Research
MiR‐21‐5p regulates mycobacterial survival and inflammatory responses by targeting Bcl‐2 and TLR4 in Mycobacterium tuberculosis‐infected macrophages
Zhonghua Zhao, Jinzhu Hao, Xia Li, Yanfang Chen, Xiaoyan Qi · 2019 · FEBS Letters
c-Jun N-Terminal Kinase Inhibitors as Potential Leads for New Therapeutics for Alzheimer’s Diseases
Stephanie Cristine Hepp Rehfeldt, Fernanda Majolo, Márcia Inês Goettert, Stefan Laufer · 2020 · International Journal of Molecular Sciences
Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma
Cristiano Guttà, Arman Rahman, Claudia Monica Aura, Peter Dynoodt, Emilie M. Charles, Elodie Hirschenhahn, Jesuchristopher Joseph, Jasper Wouters, C. de Chaumont, Máirín Rafferty et al. · 2020 · Cell Death and Disease
Pharmacologic Targeting of Mcl-1 Induces Mitochondrial Dysfunction and Apoptosis in B-Cell Lymphoma Cells in a TP53- and BAX- Dependent Manner
Tingting Liu, Vi Lam, Elana Thieme, Duanchen Sun, Xiaoguang Wang, Fei Xu, Lili Wang, Olga V. Danilova, Zheng Xia, Jeffrey W Tyner et al. · 2021 · Clinical Cancer Research
The Potential Role of Hypoxia-Inducible Factor-1 in the Progression and Therapy of Central Nervous System Diseases
Hongxiu Chen, Di Ma, Feixue Yue, Yajie Qi, Manman Dou, Liuping Cui, Yingqi Xing · 2021 · Current Neuropharmacology
Acute myeloid leukemia resistant to venetoclax-based therapy: What does the future hold?
Prajwal Dhakal, Melissa Lowe Bates, Michael H. Tomasson, Grerk Sutamtewagul, Adam J. Dupuy, Vijaya Raj Bhatt · 2022 · Blood Reviews
Role of Bcl-2 Family Proteins in Photodynamic Therapy Mediated Cell Survival and Regulation
Eric Chekwube Aniogo, Blassan Plackal Adimuriyil George, Heidi Abrahamse · 2020 · Molecules
Protective effects of hydroxy-α-sanshool from the pericarp of Zanthoxylum bungeanum Maxim. On D-galactose/AlCl3-induced Alzheimer's disease-like mice via Nrf2/HO-1 signaling pathways
Yujie Liu, Xianglong Meng, Lin Sun, Ke Pei, Lin Chen, Shuosheng Zhang, Mei-Bian Hu · 2021 · European Journal of Pharmacology
Antioxidant and anti-apoptotic effects of cannabidiol in model of ischemic stroke in rats
Sepideh Khaksar, Mohammadreza Bigdeli, Arash Samiee, Zahra Shirazi-zand · 2022 · Brain Research Bulletin
Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter
Stasė Bielskutė, Janez Plavec, Peter Podbevšek · 2021 · Nucleic Acids Research
Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules
Elisabetta Valentini, Simona D’Aguanno, Marta Di Martile, Camilla Montesano, Virginia Ferraresi, Alexandros Patsilinakos, Manuela Sabatino, Lorenzo Antonini, Martina Chiacchiarini, Sérgio Valente et al. · 2022 · Theranostics
Dual tumor- and subcellular-targeted photodynamic therapy using glucose-functionalized MoS2 nanoflakes for multidrug-resistant tumor ablation
Shaohui Xu, Pan Zhang, Isabelle Heing‐Becker, Junmei Zhang, Peng Tang, Raju Bej, Sumati Bhatia, Yinan Zhong, Rainer Haag · 2022 · Biomaterials
Therapeutic advancements in targeting BCL-2 family proteins by epigenetic regulators, natural, and synthetic agents in cancer
Arnab Sarkar, Abhik Paul, Tanmoy Banerjee, Avik Maji, Sanjukta Saha, Anupam Bishayee, Tapan Kumar Maity · 2023 · European Journal of Pharmacology
Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression
Yaxuan Zhou, Rinka Nakajima, Mashiro Shirasawa, Mariana Fikriyanti, Lin Zhao, Ritsuko Iwanaga, Andrew P. Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani · 2023 · Biology
Apoptosis and its pathways as targets for intracellular pathogens to persist in cells
Jorge Rodríguez González, Laila Gutiérrez‐Kobeh · 2023 · Parasitology Research
Exploiting metabolic cell death for cancer therapy
Chao Mao, Dadi Jiang, Albert C. Koong, Boyi Gan · 2025 · Nature reviews. Cancer
Molecular mechanisms of natural compounds in cell death induction and sensitization to chemotherapeutic drugs in lung cancer
Onsurang Wattanathamsan, Yoshihiro Hayakawa, Varisa Pongrakhananon · 2019 · Phytotherapy Research
Gypenoside Inhibits Endothelial Cell Apoptosis in Atherosclerosis by Modulating Mitochondria through PI3K/Akt/Bad Pathway
Nan Song, Lianqun Jia, Huimin Cao, Yixin Ma, Ning Chen, Si Chen, Xiaoming Lv, Guanlin Yang · 2020 · BioMed Research International
In situ delivery of biobutyrate by probiotic Escherichia coli for cancer therapy
Chung‐Jen Chiang, Yan-Hong Hong · 2021 · Scientific Reports
Inhibition of the Anti-Apoptotic Bcl-2 Family by BH3 Mimetics Sensitize the Mitochondrial Permeability Transition Pore Through Bax and Bak
Pooja Patel, Arielys Mendoza, Dexter J. Robichaux, Meng Carla Wang, Xander H.T. Wehrens, Jason M. Karch · 2021 · Frontiers in Cell and Developmental Biology
Tackling Undruggable Targets with Designer Peptidomimetics and Synthetic Biologics
Colin Swenson, Gunasheil Mandava, Deborah M. Thomas, Raymond E. Moellering · 2024 · Chemical Reviews
Wnt Signaling and Its Impact on Mitochondrial and Cell Cycle Dynamics in Pluripotent Stem Cells
Megan L. Rasmussen, Natalya A. Ortolano, Alejandra I. Romero-Morales, Vivian Gama · 2018 · Genes
Light-induced modulation of the mitochondrial respiratory chain activity: possibilities and limitations
Mariia Lunová, Barbora Smolková, Mariia Uzhytchak, Klára Žofie Janoušková, Milan Jirsa, Daria Egorova, A. V. Kulikov, Šárka Kubinová, Alexandr Dejneka, Oleg Lunov · 2019 · Cellular and Molecular Life Sciences
The Impact of Mitochondrial Fission-Stimulated ROS Production on Pro-Apoptotic Chemotherapy
Jan Ježek, Katrina F. Cooper, Randy Strich · 2021 · Biology
Targeting key proteins involved in transcriptional regulation for cancer therapy: Current strategies and future prospective
Haixiang Pei, Weikai Guo, Yangrui Peng, Hai Xiong, Yihua Chen · 2022 · Medicinal Research Reviews
Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer
Fuqiang Liu, Xiaoqing Li, Yan Han, Jiao Wu, Yichun Yang, Jin He, Jun Chen, Zhongxiang Jiang, Fan Wu, Zheng Jiang · 2022 · Cellular Signalling
MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products
Ka Iong Chan, Siyuan Zhang, Guodong Li, Yida Xu, Liao Cui, Yitao Wang, Huanxing Su, Wen Tan, Zhangfeng Zhong · 2024 · Aging and Disease
Scorpion Toxins and Ion Channels: Potential Applications in Cancer Therapy
Rosa Amalia Dueñas-Cuellar, Carlos José Correia de Santana, Ana Carolina Martins Magalhães, Osmindo Rodrigues Pires Júnior, Wagner Fontes, Mariana S. Castro · 2020 · Toxins
Latest perspectives on glucocorticoid-induced apoptosis and resistance in lymphoid malignancies
Dorien Clarisse, Fritz C. Offner, Karolien De Bosscher · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Pharmacological, nutraceutical, and nutritional properties of flaxseed ( Linum usitatissimum ): An insight into its functionality and disease mitigation
Sana Noreen, Tabussam Tufail, Huma Bader Ul Ain, Chinaza Godswill Awuchi · 2023 · Food Science & Nutrition
The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1
Steven P. O’Hara, Patrick L. Splinter, Christy E. Trussoni, Maria Eugenia Guicciardi, Noah P. Splinter, Mohammed Alsuraih, Navine Nasser‐Ghodsi, Deborah Stollenwerk, Gregory James Gores, Nicholas F. LaRusso · 2019 · Journal of Biological Chemistry
Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML
Larissa Ewald, Jessica Dittmann, Meike Vogler, Simone Fulda · 2019 · Cell Death and Disease
Skin immunity and its dysregulation in atopic dermatitis, hidradenitis suppurativa and vitiligo
Elena Campione, Caterina Lanna, Laura Diluvio, Maria Vittoria Cannizzaro, Sandro Grelli, Marco Galluzzo, Marina Talamonti, Margherita Annicchiarico‐Petruzzelli, Mara Mancini, Gerry Melino et al. · 2020 · Cell Cycle
Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax
Christian Bogner, Justin Kale, Justin P. Pogmore, Xiaoke Chi, Aisha Shamas‐Din, Cécile Fradin, Brian F. Leber, David William Andrews · 2020 · Molecular Cell
Over high or low dietary protein levels depressed the growth, TOR signaling, apoptosis, immune and anti-stress of abalone Haliotis discus hannai
Shuoli Ma, Yanlin Guo, Li Sun, Wenhao Fan, Yue Liu, Danni Liu, Dong Huang, Xinxin Li, Wenbing Zhang, Kangsen Mai · 2020 · Fish & Shellfish Immunology
Carnosic Acid Encapsulated in Albumin Nanoparticles Induces Apoptosis in Breast and Colorectal Cancer Cells
Katren F. Khella, Ahmed I. Abd El Maksoud, Amr Hassan, Shaimaa E. Abdel-Ghany, Rafaat Mohamed Elsanhoty, Mohammed Abdullah Aladhadh, Mohamed A. Abdel-Hakeem · 2022 · Molecules
A Mechanistic Evaluation of Antioxidant Nutraceuticals on Their Potential against Age-Associated Neurodegenerative Diseases
Nur Zuliani Ramli, Mohamad Fairuz Yahaya, Ikuo Tooyama, Hanafi Ahmad Damanhuri · 2020 · Antioxidants
In silico SELEX screening and statistical analysis of newly designed 5mer peptide-aptamers as Bcl-xl inhibitors using the Taguchi method
Alireza Poustforoosh, Sanaz Faramarz, Mohammad Hadi Nematollahi, Hassan Hashemipour, Manica Negahdaripour, Abbas Pardakhty · 2022 · Computers in Biology and Medicine
Vildagliptin restores cognitive function and mitigates hippocampal neuronal apoptosis in cisplatin-induced chemo-brain: Imperative roles of AMPK/Akt/CREB/ BDNF signaling cascades
Abdulla M. A. Mahmoud, Eman M. Mantawy, Sara A. Wahdan, Ramy M. Ammar, Ebtehal El‐Demerdash · 2023 · Biomedicine & Pharmacotherapy
Comprehensive evaluation of mitochondrial redox profile, calcium dynamics, membrane integrity and apoptosis markers in a preclinical model of severe penetrating traumatic brain injury
Jignesh D. Pandya, Sudeep Musyaju, Hiren R. Modi, Ying Jun Cao, William J. Flerlage, Linda Huynh, Brittany Kociuba, Nishant P. Visavadiya, Firas H. Kobeissy, Kevin Wang et al. · 2023 · Free Radical Biology and Medicine
Stroke in the Time of Circadian Medicine
Philipp Mergenthaler, Joyce Saleh Balami, Ain A. Neuhaus, Amin Mottahedin, Gregory W. Albers, Peter Malcolm Rothwell, Jeffrey L. Saver, Martin Elliot Young, Alastair Mitchell Buchan · 2024 · Circulation Research
Role of Apoptosis in Cancer Resistance to Chemotherapy
Lichan Chen, Yanyun Zeng, Shufeng Zhou · 2018 · InTech eBooks
Mitochondria as emerging targets for therapies against T cell acute lymphoblastic leukemia
Miguel Olivas-Aguirre, Igor I. Pottosin, Oxana R. Dobrovinskaya · 2019 · Journal of Leukocyte Biology
Cytotoxicity of biodegradable magnesium alloy WE43 to tumor cells in vitro: Bioresorbable implants with antitumor activity?
N. Yu. Anisimova, Mikhail Kiselevskiy, Natalia Sergeevna Martynenko, Boris Borisovich Straumal, Regine Willumeit‐Römer, Sergey Vladimirovich Dobatkin, Yuri Estrin · 2019 · Journal of Biomedical Materials Research Part B Applied Biomaterials
The flavonoid Astragalin shows anti‐tumor activity and inhibits PI3K/AKT signaling in gastric cancer
Zhongqing Wang, Jian Lv, Xiufang Li, Qing Lin · 2021 · Chemical Biology & Drug Design
Programmed cell death in tumor immunity: mechanistic insights and clinical implications
Man Wang, Fei Yu, Yuan Zhang, Peifeng Li · 2024 · Frontiers in Immunology
Management of ROS and Regulatory Cell Death in Myocardial Ischemia–Reperfusion Injury
Ge Gong, Wenhui Wan, Xinghu Zhang, Xiangxuan Chen, Jian Ping Yin · 2024 · Molecular Biotechnology
Valorization of Soy Whey Wastewater: How Epigallocatechin-3-gallate Regulates Protein Precipitation
Zejian Xu, Nairong Hao, Lianwei Li, Yan Zhang, Liangli Lucy Yu, Lianzhou Jiang, Xiaonan Sui · 2019 · ACS Sustainable Chemistry & Engineering
Beyond detergent micelles: The advantages and applications of non-micellar and lipid-based membrane mimetics for solution-state NMR
Kai Klöpfer, Franz Hagn · 2019 · Progress in Nuclear Magnetic Resonance Spectroscopy
EGFR/FOXO3a/BIM signaling pathway determines chemosensitivity of BMP4-differentiated glioma stem cells to temozolomide
Iwona Anna Ciechomska, Bartłomiej Gielniewski, Bartosz Wojtaś, Bozena Kaminska, Jakub Mieczkowski · 2020 · Experimental & Molecular Medicine
Glycyrrhizin Mediates Downregulation of Notch Pathway Resulting in Initiation of Apoptosis and Disruption in the Cell Cycle Progression in Cervical Cancer Cells
Afza Ahmad, Rohit Kumar Tiwari, Mοhd Saeed, Irfan S. Ahmad, Irfan Ahmad Ansari · 2021 · Nutrition and Cancer
Structure-based design approach of potential BCL-2 inhibitors for cancer chemotherapy
Swati Krishna, S. Birendra Kumar, T. P. Krishna Murthy, Manikanta Murahari · 2021 · Computers in Biology and Medicine
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma
Florian Selt, Romain Sigaud, Gintvile Valinciute, Philipp Sievers, Julia Zaman, Clara Alcon, Simone Schmid, Heike Peterziel, Jessica W. Tsai, Romain Guiho et al. · 2022 · Neuro-Oncology
FLIM reveals alternative EV-mediated cellular up-take pathways of paclitaxel
H Saari, Ekaterina S. Lisitsyna, Kaisa Rautaniemi, Tatu Rojalin, L. Niemi, O. Nivaro, Timo Laaksonen, Marjo L. Yliperttula, Elina Vuorimaa · 2018 · Journal of Controlled Release
Contribution of Mitochondrial Ion Channels to Chemo-Resistance in Cancer Cells
Roberta Peruzzo, Ildikò Szabó · 2019 · Cancers
Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis
Estefanía Lucendo, Mónica Sancho, Fabio Lolicato, Matti Javanainen, Waldemar Kulig, Diego Leiva, Gerard Duart, Vicente Andreu-Férnández, Ismael Mingarro, Mar Orzáez · 2020 · Proceedings of the National Academy of Sciences
Mcl-1 Inhibition: Managing Malignancy in Multiple Myeloma
Omar S. Al‐Odat, Max Von Suskil, Robert J. Chitren, Weam Othman Elbezanti, Sandeep Kumar Srivastava, Tülin Budak-Alpdoǧan, Subash C. Jonnalagadda, Bharat Bhushan Aggarwal, Manoj Kumar Pandey · 2021 · Frontiers in Pharmacology
Unraveling the role of tomato Bcl-2-associated athanogene (BAG) proteins during abiotic stress response and fruit ripening
Mohammad Irfan, Pankaj Kumar, Irshad Ahmad, Asis Datta · 2021 · Scientific Reports
Modulation of Ca2+ signaling by antiapoptotic Bcl-2 versus Bcl-xL: From molecular mechanisms to relevance for cancer cell survival
Nicolas Rosa, Femke Speelman-Rooms, Jan B. Parys, Geert Bultynck · 2022 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
The complex interplay between autophagy and cell death pathways
Christina Ploumi, Margarita-Elena Papandreou, Nektarios Tavernarakis · 2022 · Biochemical Journal
Regorafenib Induces Bim-Mediated Intrinsic Apoptosis by Blocking AKT-Mediated FOXO3a Nuclear Export
Beini Sun, Hongce Chen, Xiaoping Wang, Tongsheng Chen · 2022 · Cell Death Discovery
Self-assembled fluorescent hybrid nanoparticles-mediated collaborative lncRNA CCAT1 silencing and curcumin delivery for synchronous colorectal cancer theranostics
Fan Jia, Yunhao Li, Xiongwei Deng, Xuan Wang, Xinyue Cui, Jianqing Lu, Zian Pan, Yan Fen Wu · 2021 · Journal of Nanobiotechnology
Marine Anthraquinones: Pharmacological and Toxicological Issues
Giulia Greco, Eleonora Turrini, Elena Catanzaro, Carmela Fimognari · 2021 · Marine Drugs
Merkel Cell Carcinoma from Molecular Pathology to Novel Therapies
Karolina Stachyra, Monika Dudzisz‐Śledź, Elżbieta Bylina, Anna Szumera‐Ciećkiewicz, Mateusz Jacek Spalek, Ewa Bartnik, Piotr Lukasz Rutkowski, Anna Malgorzata Czarnecka · 2021 · International Journal of Molecular Sciences
The Incomplete Puzzle of the BCL2 Proteins
Flores-Romero, Hector, García-Sáez, Ana J. · 2019 · Cells
B-Cell Lymphoma 2 (Bcl-2) and Regulation of Apoptosis after Traumatic Brain Injury: A Clinical Perspective
Hansen Deng, John K. Yue, Benjamin E. Zusman, Enyinna L. Nwachuku, Hussam Abou‐Al‐Shaar, Pavan S. Upadhyayula, David O. Okonkwo, Ava M. Puccio · 2020 · Medicina
Status of kinases in Epstein-Barr virus and Helicobacter pylori Coinfection in gastric Cancer cells
Charu Sonkar, Tarun Verma, Debi Chatterji, Ajay Kumar Jain, Hem Chandra Jha · 2020 · BMC Cancer
BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening
Martijn Kerkhofs, Rita La Rovere, Kirsten Welkenhuysen, Ann M. Janssens, Peter Vandenberghe, Muniswamy Madesh, Jan B. Parys, Geert Bultynck · 2021 · Cell Calcium
Myeloid cell leukemia 1 (MCL-1): Structural characteristics and application in cancer therapy
Pooja Mittal, Sujata Singh, Rajesh Sinha, Anju Shrivastava, Archana Kumari Singh, Indrakant Kumar Singh · 2021 · International Journal of Biological Macromolecules
Autophagy: A Key Player in Pancreatic Cancer Progression and a Potential Drug Target
Josef Gillson, Yomna S. Abd El-Aziz, Lionel Yi Wen Leck, Patric J. Jansson, Nick Pavlakis, Jaswinder Singh Samra, Anubhav Mittal, Sumit Sahni · 2022 · Cancers
SMMPPI: a machine learning-based approach for prediction of modulators of protein–protein interactions and its application for identification of novel inhibitors for RBD:hACE2 interactions in SARS-CoV-2
Priya Gupta, Debasisa Mohanty · 2021 · Briefings in Bioinformatics
Apoptosis during ZIKA Virus Infection: Too Soon or Too Late?
Jonathan Turpin, Daed El Safadi, Grégorie Lebeau, Morgane Krejbich, Camille Chatelain, Philippe Desprès, Wildriss Viranaïcken, Pascale Krejbich Trotot · 2022 · International Journal of Molecular Sciences
Induction of G0/G1�phase arrest and apoptosis by CRISPR/Cas9‑mediated knockout of CDK2 in A375 melanocytes
Houguang Liu, Zheng Li, Shanshan Huo, Qiongling Wei, Ling Ge · 2019 · Molecular and Clinical Oncology
Emerging Evidence Highlighting the Importance of Redox Dysregulation in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS)
Cyril Jones Jagaraj, Sonam Parakh, Julie D. Atkin · 2021 · Frontiers in Cellular Neuroscience
Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis
Luke A. Clifton, Hanna Pauliina Wacklin, Jörgen Ådén, Ameeq Ul Mushtaq, Tobias Sparrman, Gerhard Gröbner · 2023 · Science Advances
Sublethal engagement of apoptotic pathways in residual cancer
Shane T. Killarney, Stephen W. G. Tait, Douglas R. Green, Kris C. Wood · 2023 · Trends in Cell Biology
Role of Extrinsic Apoptotic Signaling Pathway during Definitive Erythropoiesis in Normal Patients and in Patients with β-Thalassemia
Olga Raducka-Jaszul, Dżamila M. Bogusławska, Natalia Jędruchniewicz, Aleksander F. Sikorski · 2020 · International Journal of Molecular Sciences
Folate Functionalized and Evodiamine‐Loaded Pluronic Nanomicelles for Augmented Cervical Cancer Cell Killing
Raghu Solanki, Ashok Kumar Jangid, Mahima Jadav, Hitesh Kulhari, Sunita Patel · 2023 · Macromolecular Bioscience
Calcium signaling in lysosome-dependent cell death
Mateus Milani, Philippe Pihán, Claudio A. Hetz · 2023 · Cell Calcium
Ferulic acid ameliorates pentylenetetrazol-induced seizures by reducing neuron cell death
Shu-Hong Zhang, Dong Liu, HU Qing-yun, Jinling Zhu, Shuqiu Wang, Shaobo Zhou · 2019 · Epilepsy Research
Phytochemical constituents and anticancer activities of Tarchonanthus camphoratus essential oils grown in Saudi Arabia
Fahd Ali Nasr, Omar M. Noman, Ali Saeed Alqahtani, Wajhul Qamar, Syed Rizwan Ahamad, Abdullah A. Al-Mishari, Nouf Al-yhya, Muhammad Farooq · 2020 · Saudi Pharmaceutical Journal
Mitochondrial dynamics, quality control, and mtDNA in alcohol-associated liver disease and liver cancer
Xiaowen Ma, Mengwei Niu, Hong‐Min Ni, Wen‐Xing Ding · 2024 · Hepatology
Neurophysiological changes in simulated microgravity: An animal model
Christiane M. Nday, Christos A. Frantzidιs, Graham Ellis Jackson, Panagiotis D. Bamidis, Chrysoula Kourtidou‐Papadeli · 2019 · Neurology India
Role of BCL-2 Family Proteins in Apoptosis and its Regulation by Nutrients
Chen Zheng, Ting Liu, Huihui Liu, Jing Wang · 2019 · Current Protein and Peptide Science
Granzymes and Mitochondria
Dmitry B. Kiselevsky · 2020 · Biochemistry (Moscow)