Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Golestaneh, Nady, Chu, Yi, Xiao, Yang-Yu, Stoleru, Gianna L, Theos, Alexander C·2017·Cell Death & Disease

Cited by (357)

Items 101–200 of 357

  1. Investigating mitochondrial fission, fusion, and autophagy in retinal pigment epithelium from donors with age-related macular degeneration
    Cody R. Fisher, Adam A. Shaaeli, Mara C. Ebeling, Sandra Rocio Montezuma, Deborah A. Ferrington · 2022 · Scientific Reports
  2. Transient acceleration of autophagic degradation by pharmacological Nrf2 activation is important for retinal pigment epithelium cell survival
    Yuichi Saito, Yoshiki Kuse, Yuki Inoue, Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa · 2018 · Redox Biology
  3. Enhanced Delivery of siRNA to Retinal Ganglion Cells by Intravitreal Lipid Nanoparticles of Positive Charge
    Xiaonan Huang, Ying Chau · 2020 · Molecular Pharmaceutics
  4. Modeling of mitochondrial bioenergetics and autophagy impairment in MELAS-mutant iPSC-derived retinal pigment epithelial cells
    Sujoy Bhattacharya, Jinggang Yin, Weihong Huo, Edward Chaum · 2022 · Stem Cell Research & Therapy
  5. Exposure of Macrophages to Low-Dose Gadolinium-Based Contrast Medium: Impact on Oxidative Stress and Cytokines Production
    Te−I Weng, Huang Jen Chen, Chen‐Wen Lu, Yu-Chin Ho, Jia-Lun Wu, Shing‐Hwa Liu, Jong‐Kai Hsiao · 2018 · Contrast Media & Molecular Imaging
  6. The Role of Autophagy in Eye Diseases
    José A. Fernández‐Albarral, Esther de Julián-López, Carmen Soler-Domínguez, Rosa de Hoz, Inés López‐Cuenca, Elena Salobrar‐García, Jose Manuel Ramirez, Maria Dolores Pinazo-Duran, Juan Jose Salazar, Ana Isabel Ramirez · 2021 · Life
  7. The Diverse Bioactivity of α-mangostin and Its Therapeutic Implications
    Tejashri Chavan, Aaron Muth · 2021 · Future Medicinal Chemistry
  8. Exfoliation Syndrome: A Disease of Autophagy and LOXL1 Proteopathy
    Audrey M. Bernstein, Robert H. Ritch, Jose Mario Wolosin · 2018 · Journal of Glaucoma
  9. Potential Protective and Therapeutic Roles of the Nrf2 Pathway in Ocular Diseases: An Update
    Ming-xuan Wang, Jing Zhao, Hong Zhang, Ke Li, Lingzhi Niu, Yuanping Wang, Yajuan Zheng · 2020 · Oxidative Medicine and Cellular Longevity
  10. Role of retinal pigment epithelium in age-related macular disease: a systematic review
    Alan C. Bird · 2020 · British Journal of Ophthalmology
  11. Vitreous humor proteome: unraveling the molecular mechanisms underlying proliferative and neovascular vitreoretinal diseases
    Fátima Milhano Santos, Sergio Ciordia, Joana Mesquita, João Paulo Castro Sousa, Alberto Paradela, Cândida Teixeira Tomaz, Luís A. Passarinha · 2022 · Cellular and Molecular Life Sciences
  12. Antioxidant Role of PRGF on RPE Cells after Blue Light Insult as a Therapy for Neurodegenerative Diseases
    Carlota Suárez‐Barrio, Susana del Olmo‐Aguado, Eva García-Pérez, María de la Fuente, Francisco Muruzábal, Eduardo Anitua, Begoña Baamonde-Arbaiza, Luis Fernández-Vega-Cueto, Luis Fernández-Vega-Cueto, Jesús Merayo-Llovés · 2020 · International Journal of Molecular Sciences
  13. Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration
    Luminita Paraoan, Umar Sharif, Emil Carlsson, Wasu Supharattanasitthi, Nur Musfirah Mahmud, Tengku Ain Kamalden, Paul Stephenson Hiscott, Malcolm Joseph Jackson, Ian Grierson · 2020 · Progress in Retinal and Eye Research
  14. Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degeneration
    Parameswaran Gangadharan Sreekumar, Ram Kannan · 2020 · Redox Biology
  15. Vitreous Humor Proteome: Targeting Oxidative Stress, Inflammation, and Neurodegeneration in Vitreoretinal Diseases
    Fátima Milhano Santos, Joana Mesquita, João Paulo Castro Sousa, Sergio Ciordia, Alberto Paradela, Cândida Teixeira Tomaz · 2022 · Antioxidants
  16. The contribution of pattern recognition receptor signalling in the development of age related macular degeneration: the role of toll-like-receptors and the NLRP3-inflammasome
    Alice A. Brandli, Kirstan A. Vessey, Erica Lucy Fletcher · 2024 · Journal of Neuroinflammation
  17. Suppression of AMD-Like Pathology by Mitochondria-Targeted Antioxidant SkQ1 Is Associated with a Decrease in the Accumulation of Amyloid β and in mTOR Activity
    Natalia A. Muraleva, Oyuna S. Kozhevnikova, А. Ж. Фурсова, Nataliya G. Kolosova · 2019 · Antioxidants
  18. 7-Ketocholesterol disturbs RPE cells phagocytosis of the outer segment of photoreceptor and induces inflammation through ERK signaling pathway
    Chen Yang, Lirong Xie, Qing Gu, Qinghua Qiu, Xingwei Wu, Lili Yin · 2019 · Experimental Eye Research
  19. All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells
    Lingmin Zhang, Yingying Zhou, Qingqing Xia, Ying Chen, Jie Li · 2020 · Toxicology Letters
  20. Discovering the Potential of Natural Antioxidants in Age-Related Macular Degeneration: A Review
    Kah-Hui Wong, Hui-Yin Nam, Sze Yuen Lew, Murali K. Naidu, Pamela Rosie David, Tengku Ain Kamalden, Siti Nurma Hanim Hadie, Lee Wei Lim · 2022 · Pharmaceuticals
  21. Recent Advances in Our Understanding of Age-Related Macular Degeneration: Mitochondrial Dysfunction, Redox Signaling, and the Complement System
    Francesco Buonfiglio, Christina A. Korb, Bernhard M. Stoffelns, Norbert Pfeiffer, Adrian Gericke · 2024 · Aging and Disease
  22. Urolithin A promotes p62-dependent lysophagy to prevent acute retinal neurodegeneration
    Juan Ignacio Jiménez‐Loygorri, Álvaro Viedma-Poyatos, Raquel Gómez‐Sintes, Patricia Boya · 2024 · Molecular Neurodegeneration
  23. Treatment of neovascular age-related macular degeneration with anti-vascular endothelial growth factor drugs: progress from mechanisms to clinical applications
    S. Cheng, Shu Zhang, Mingyan Huang, Yuxuan Liu, Xunyu Zou, Xiaoming Chen, Zuhai Zhang · 2024 · Frontiers in Medicine
  24. Renin–angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models
    Norihiro Nagai, Hirohiko Kawashima, Eriko Toda, Kohei Homma, Hideto Osada, Naymel Alejandra Guzmán Mendoza, Shinsuke Shibata, Yasuo Uchiyama, Hideyuki Okano, Kazuo Tsubota et al. · 2020 · Communications Biology
  25. Autophagy in the eye: from physiology to pathophysiology
    Paloma B. Liton, Kathleen Boesze‐Battaglia, Michael E. Boulton, Patricia Boya, Thomas A. Ferguson, Ian G. Ganley, Anu Kauppinen, Gordon W. Laurie, Noboru Mizushima, Hideaki Morishita et al. · 2023 · Autophagy Reports
  26. Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE‐19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways
    Nicoletta Marchesi, Natthakan Thongon, Alessia Pascale, Alessandro Provenzani, Ali K. J. Koskela, Eveliina Korhonen, Adrian Smędowski, Stefano M. Govoni, Anu Kauppinen, Kai Kaarniranta et al. · 2018 · Oxidative Medicine and Cellular Longevity
  27. Lycium barbarum polysaccharide protects ARPE‑19 cells against H2O2‑induced oxidative stress via the Nrf2/HO‑1 pathway
    Ran Liang, Qi Zhao, Qing Chun Zhu, Xin He, Mingjun Gao, Yiru Wang · 2021 · Molecular Medicine Reports
  28. Photobiology of lipofuscin granules in the retinal pigment epithelium cells of the eye: norm, pathology, age
    T. B. Feldman, Alexander E. Dontsov, M. A. Yakovleva, М. А. Оstrovsky · 2022 · Biophysical Reviews
  29. Endogenous and Exogenous Regulation of Redox Homeostasis in Retinal Pigment Epithelium Cells: An Updated Antioxidant Perspective
    Yu. V. Markitantova, V. N. Simirskii · 2023 · International Journal of Molecular Sciences
  30. Lipopolysaccharide-Induced Autophagy Mediates Retinal Pigment Epithelium Cells Survival. Modulation by the Phospholipase D Pathway
    Vicente Bermúdez, Paula Estefanía Tenconi, Norma Maria Giusto, Melina V. Mateos · 2019 · Frontiers in Cellular Neuroscience
  31. Formation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction
    Cristina Escrevente, Ana S. Falcão, Michael J. Hall, Mafalda Lopes‐da‐Silva, Pedro Antas, Miguel Mesquita, Inês S. Ferreira, Helena Cardoso, Daniela Oliveira, Ana C. Fradinho et al. · 2021 · Investigative Ophthalmology & Visual Science
  32. Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation
    Émilie Heckel, Gaël Cagnone, Tapan Agnihotri, Bertan Cakir, Ashim Das, Jin Sung Kim, Nicholas Kim, Geneviève Lavoie, Anu Situ, Sheetal Pundir et al. · 2022 · JCI Insight
  33. Ambra1haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration
    Ignacio Ramírez‐Pardo, Beatriz Villarejo‐Zori, Juan Ignacio Jiménez‐Loygorri, Elena Sierra‐Filardi, Sandra Alonso‐Gil, Guillermo Mariño, Pedro de la Villa, Patrick S. Fitze, José Manuel Fuentes, Ramón García‐Escudero et al. · 2022 · Autophagy
  34. Regulation of oxidative stress and inflammatory responses in human retinal pigment epithelial cells
    Niina Bhattarai · 2022 · Acta Ophthalmologica
  35. PARP1 Impedes SIRT1-Mediated Autophagy during Degeneration of the Retinal Pigment Epithelium under Oxidative Stress.
    Ki-Hong Jang, Yeseong Hwang, Eunhee Kim · 2020 · PubMed Central
  36. Decorin Protects Retinal Pigment Epithelium Cells from Oxidative Stress and Apoptosis via AMPK‐mTOR‐Regulated Autophagy
    Xinyi Xie, Duo Li, Yuqing Cui, Tianhua Xie, Jiping Cai, Yong Yao · 2022 · Oxidative Medicine and Cellular Longevity
  37. Hydroxychloroquine Causes Early Inner Retinal Toxicity and Affects Autophagosome–Lysosomal Pathway and Sphingolipid Metabolism in the Retina
    Koushik Mondal, Hunter L. Porter, Jerome Cole, Hemang K. Pandya, Sandip Kumar Basu, Sufiya Khanam, Chi‐Yang Chiu, Vinay A. Shah, Daniel Stephenson, Charles Edward Chalfant et al. · 2022 · Molecular Neurobiology
  38. mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells
    David Adrian Merle, Francesca Provenzano, Mohamed Ali Jarboui, Ellen Kilger, Simon J. Clark, Michela Deleidi, Angela Armento, Marius Ueffing · 2021 · Antioxidants
  39. The Anti-Aging Hormone Klotho Promotes Retinal Pigment Epithelium Cell Viability and Metabolism by Activating the AMPK/PGC-1α Pathway
    Shuyan Zhou, Jacob Hum, Kaan Taskintuna, Stephanie Olaya, Jeremy Steinman, Junfeng Ma, Nady Golestaneh · 2023 · Antioxidants
  40. PEDF protects human retinal pigment epithelial cells against oxidative stress via upregulation of UCP2 expression
    Xia Wang, Xu Liu, Yuan Ren, Ying Liu, Shuangyu Han, Jingkang Zhao, Xingchun Gou, Yuan He · 2018 · Molecular Medicine Reports
  41. Testing Mitochondrial-Targeted Drugs in iPSC-RPE from Patients with Age-Related Macular Degeneration
    Mara C. Ebeling, Zhaohui Geng, Madilyn R. Stahl, Rebecca J. Kapphahn, Heidi Roehrich, Sandra Rocio Montezuma, Deborah A. Ferrington, James R. Dutton · 2022 · Pharmaceuticals
  42. Sodium Iodate Disrupted the Mitochondrial-Lysosomal Axis in Cultured Retinal Pigment Epithelial Cells
    Yingcheng Lin, Lin‐Yea Horng, Hui‐Ching Sung, Rong-Tsun Wu · 2018 · Journal of Ocular Pharmacology and Therapeutics
  43. Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells
    Eveliina Korhonen, Maria Hytti, Niina Piippo, Kai Kaarniranta, Anu Kauppinen · 2021 · Experimental Eye Research
  44. Interplay between reactive oxygen species and autophagy in the course of age-related macular degeneration
    Małgorzata Nita, Andrzej E. Grzybowski · 2020 · EXCLI journal
  45. Antioxidants and Mechanistic Insights for Managing Dry Age-Related Macular Degeneration
    Deepak Basyal, Sooyeun Lee, Hye Jin Kim · 2024 · Antioxidants
  46. Recent developments of neuroprotective agents for degenerative retinal disorders
    Jiahui Wu, Kepeng Ou, Youjian Li, Ling Liu, Hua Li, Katherine H. M. Cox, Jian Liu, Andrew D. Dick · 2022 · Neural Regeneration Research
  47. Thymoquinone in Ocular Neurodegeneration: Modulation of Pathological Mechanisms via Multiple Pathways
    Nur Musfirah Mahmud, Luminita Paraoan, Nurliza Khaliddin, Tengku Ain Kamalden · 2022 · Frontiers in Cellular Neuroscience
  48. Polydopamine Nanoparticles as Mimicking RPE Melanin for the Protection of Retinal Cells Against Blue Light‐Induced Phototoxicity
    Yong‐Su Kwon, Julie Munsoor, Mary Kaufmann, Min Zheng, Alex I. Smirnov, Zongchao Han · 2024 · Advanced Science
  49. Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells
    Viren Govindaraju, Manish Bodas, Neeraj Vij · 2017 · PLoS ONE
  50. Urban Aerosol Particulate Matter Promotes Necrosis and Autophagy via Reactive Oxygen Species-Mediated Cellular Disorders that Are Accompanied by Cell Cycle Arrest in Retinal Pigment Epithelial Cells
    Hyesook Lee, Da Hye Kim, Jeong-Hwan Kim, Seh-Kwang Park, Ji-Won Jeong, Mi-Young Kim, Seok‐Ho Hong, Kyoung Seob Song, Gi‐Young Kim, Jin Won Hyun et al. · 2021 · Antioxidants
  51. Potential of Telomerase in Age-Related Macular Degeneration—Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α
    Janusz Błasiak, Joanna Szczepańska, Michał Fila, Elżbieta Pawłowska, Kai Kaarniranta · 2021 · International Journal of Molecular Sciences
  52. The Potential of Selenium-Based Therapies for Ocular Oxidative Stress
    Lulwah Al-Bassam, Gemma C. Shearman, Steve Brocchini, Raid Ghassan Alany, Gareth R. Williams · 2024 · Pharmaceutics
  53. Depletion of the Third Complement Component Ameliorates Age‐Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model
    Dorota Rogińska, Miłosz Piotr Kawa, Ewa Pius‐Sadowska, Renata Lejkowska, Karolina Łuczkowska, Barbara Wiszniewska, Kai Kaarniranta, Jussi J. Paterno, Christian Andreas Schmidt, Bogusław Machaliński et al. · 2017 · Oxidative Medicine and Cellular Longevity
  54. Gene therapy for age-related macular degeneration: a promising frontier in vision preservation
    Kiavash Hushmandi, Hiu Yan Lam, Wendy Wong, Wency Tan, Seyed‐Hashem Daryabari, R. J. Reiter, Najma Farahani, Alan Prem Kumar · 2025 · Cell Communication and Signaling
  55. Benefits of plant carotenoids against age-related macular degeneration
    Dao M. Nguyen, Thilini Rasika Thrimawithana, Terrence J. Piva, Danilla Grando, Tien T. Huynh · 2023 · Journal of Functional Foods
  56. Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells
    Md. Razaul Karim, Cody R. Fisher, Rebecca J. Kapphahn, Jorge R. Polanco, Deborah A. Ferrington · 2020 · PLoS ONE
  57. A Simple Route to the Complexation of Lutein with Reduced Graphene Oxide Nanocarriers and Antioxidant Protection Against Blue Light
    Seon Yeong Chae, Min Chan Shin, Sangheon Jeon, Moon Sung Kang, Dong‐Wook Han, Suck Won Hong · 2021 · International Journal of Nanomedicine
  58. Increased risk of Parkinson’s disease among patients with age-related macular degeneration
    Po‐Yu Chen, Lei Wan, Jung‐Nien Lai, Chih Sheng Chen, Jamie Jiin-Yi Chen, Wu Ming Yen, Lu‐Ting Chiu, Kai-Chieh Hu, Peng‐Tai Tien, Hui‐Ju Lin · 2021 · BMC Ophthalmology
  59. Microbiota mitochondria disorders as hubs for early age-related macular degeneration
    János Fehér, Ágnes Élő, Lilla István, Zoltán Zsolt Nagy, Zsolt O. Radak, Gianluca Scuderi, Marco Artico, Illés Kovács · 2022 · GeroScience
  60. Oxidative stress‐induced lncRNA CYLD‐AS1 promotes RPE inflammation via Nrf2/ miR ‐134‐5p/ NF‐κB signaling pathway
    Han Du, Zixin Huang, Xin Zhou, Xielan Kuang, Chongde Long, Han Tang, Jingshu Zeng, Hao Huang, Huijun Liu, Binbin Zhu et al. · 2022 · The FASEB Journal
  61. Ginkgo biloba extracts (GBE) protect human RPE cells from t-BHP-induced oxidative stress and necrosis by activating the Nrf2-mediated antioxidant defence
    Yue Li, Xue Zhu, Ke Wang, Ling Zhu, Michael T. Murray, Fanfan Zhou · 2022 · Journal of Pharmacy and Pharmacology
  62. Homeostasis and dyshomeostasis of the retina
    Chang-Jun Zhang, Zi‐Bing Jin · 2023 · Current Medicine
  63. Effects of senescent secretory phenotype acquisition on human retinal pigment epithelial stem cells
    Raffaella Lazzarini, Michele Nicolai, Vittorio Pirani, Cesare Mariotti, Roberto Di Primio · 2018 · Aging
  64. Retinal dystrophy associated with Danon disease and pathogenic mechanism through LAMP2-mutated retinal pigment epithelium
    Masaya Fukushima, Tatsuya Inoue, Takashi Miyai, Ryo Obata · 2019 · European Journal of Ophthalmology
  65. Does senescence play a role in age-related macular degeneration?
    Goldis Malek, Judith Campisi, Koji Kitazawa, Corey M. Webster, Aparna Lakkaraju, Dorota Skowronska‐Krawczyk · 2022 · Experimental Eye Research
  66. Hydrogen sulfide protects retinal pigment epithelium cells against ferroptosis through the AMPK- and p62-dependent non-canonical NRF2-KEAP1 pathway
    Meng Yu, Weiyan Wang, Jingye Dang, Binghua Liu, Junling Xu, Jingjing Li, Yang Liu, Libo He, Yuling Ying, Jiaxiu Cai et al. · 2022 · Experimental Cell Research
  67. Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress
    Yijing Yang, Ying Wang, Ying Jie Deng, Xiaoqing Liu, Jing Lu, Jun Peng, Jie Li, Ya-Sha Zhou, Hui-An Zhu, Bo Li et al. · 2023 · Oxidative Medicine and Cellular Longevity
  68. MicroRNA-24 protects retina from degeneration in rats by down-regulating chitinase-3-like protein 1
    Chunpin Lian, Hui Ping Lou, Jingfa Zhang, Haibin Tian, Qingjian Ou, Jingying Xu, Caixia Jin, Furong Gao, Jieping Zhang, Juan Wang et al. · 2019 · Experimental Eye Research
  69. Melatonin as the Possible Link Between Age-Related Retinal Degeneration and the Disrupted Circadian Rhythm in Elderly
    Nadezda A. Stepicheva, Joseph Weiss, Peng Shang, Meysam Yazdankhah, Sayan Ghosh, Imran Ahmed Bhutto, Stacey Hose, J. Samuel Zigler, Debasish Sinha · 2019 · Advances in experimental medicine and biology
  70. Immunization Against Oxidized Elastin Exacerbates Structural and Functional Damage in Mouse Model of Smoke-Induced Ocular Injury
    Balasubramaniam Annamalai, Crystal Nicholson, Nathaniel Parsons, Sarah Stephenson, Carl Atkinson, Bryan William Jones, Bärbel Rohrer · 2020 · Investigative Ophthalmology & Visual Science
  71. Mitochondria: The Retina’s Achilles’ Heel in AMD
    Deborah A. Ferrington, M. Cristina Kenney, Shari R. Atilano, James B. Hurley, Emily E. Brown, John D. Ash · 2021 · Advances in experimental medicine and biology
  72. Antioxidative Role of Heterophagy, Autophagy, and Mitophagy in the Retina and Their Association with the Age-Related Macular Degeneration (AMD) Etiopathogenesis
    Małgorzata Nita, Andrzej E. Grzybowski · 2023 · Antioxidants
  73. Metabolic reprogramming of the retinal pigment epithelium by cytokines associated with age-related macular degeneration
    David Hansman, Yuefang Ma, Danièl Thomas, Justine R. Smith, Robert James Casson, Daniel J. Peet · 2024 · Bioscience Reports
  74. Molecular Mechanisms of Complement System Proteins and Matrix Metalloproteinases in the Pathogenesis of Age-Related Macular Degeneration
    Naima Mansoor, Fazli Wahid, Maleeha Azam, Khadim Shah, Anneke I. den Hollander, Raheel Qamar, Humaira Ayub · 2019 · Current Molecular Medicine
  75. 4-(Phenylsulfanyl) Butan-2-One Attenuates the Inflammatory Response Induced by Amyloid-β Oligomers in Retinal Pigment Epithelium Cells
    Peeraporn Varinthra, Shun‐Ping Huang, Supin Chompoopong, Zhi‐Hong Wen, Ingrid Y. Liu · 2020 · Marine Drugs
  76. The Challenge of Dimethyl Fumarate Repurposing in Eye Pathologies
    Federico Manai, Stefano M. Govoni, Marialaura Amadio · 2022 · Cells
  77. Chronic retinal injury induced by white LED light with different correlated color temperatures as determined by microarray analyses of genome-wide expression patterns in mice
    Chen Xie, Hong Zhu, Shuyang Chen, Yingying Wen, Le Jin, Liyue Zhang, Jianping Tong, Ye Shen · 2020 · Journal of Photochemistry and Photobiology B Biology
  78. Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B)
    Daniele, Lauren L., Caughey, Jennifer, Volland, Stefanie, Sharp, Rachel C., Dhingra, Anuradha, Williams, David S., Philp, Nancy J., Boesze-Battaglia, Kathleen · 2019 · American Journal of Physiology-Cell Physiology
  79. Targeting Lysosomal Dysfunction and Oxidative Stress in Age-Related Macular Degeneration
    Ana S. Falcão, Margarida L. Pedro, Sandra Tenreiro, Miguel C. Seabra · 2025 · Antioxidants
  80. Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells
    Mooud Amirkavei, Flavia Plastino, Anders Kvanta, Kai Kaarniranta, Helder André, Ari Koskelainen · 2022 · Cells
  81. Fat mass and obesity‐associated protein alleviates Aβ1–40 induced retinal pigment epithelial cells degeneration via PKA/CREB signaling pathway
    Yifan Hu, Jieqiong Chen, Yuwei Wang, Junran Sun, Peirong Huang, Jingyang Feng, Te Liu, Xiaodong Sun · 2022 · Cell Biology International
  82. Stages, pathogenesis, clinical management and advancements in therapies of age-related macular degeneration
    Ishita Shome, Neethi Chandra Thathapudi, Bindu Madhava Reddy Aramati, Bhavani S. Kowtharapu, Jaganmohan Reddy Jangamreddy · 2023 · International Ophthalmology
  83. Printable Graphene Oxide Micropatterns for a Bio‐Subretinal Chip
    Jia‐Wei Yang, Ming‐Liang Tseng, Yu‐Min Fu, Che-Hao Kang, Yu‐Ting Cheng, Po‐Han Kuo, Chi‐Kuan Tzeng, Shih‐Hwa Chiou, Chung‐Yu Wu, Guan‐Yu Chen · 2018 · Advanced Healthcare Materials
  84. Transcriptome-Wide Analysis of CXCR5 Deficient Retinal Pigment Epithelial (RPE) Cells Reveals Molecular Signatures of RPE Homeostasis
    Madhu Sudhana Saddala, Anton Lennikov, Anthony Mukwaya, Huang Hu · 2020 · Biomedicines
  85. The CD36 Ligand‐Promoted Autophagy Protects Retinal Pigment Epithelial Cells from Oxidative Stress
    Marie‐France Dorion, Mukandila Mulumba, Shuya Kasai, Ken Itoh, William D. Lubell, Huy Ong · 2021 · Oxidative Medicine and Cellular Longevity
  86. Role of Nuclear Factor of Activated T Cells (NFAT) Pathway in Regulating Autophagy and Inflammation in Retinal Pigment Epithelial Cells
    Hsuan-Yeh Pan, Ashley V. Ladd, Manas R. Biswal, Mallika Valapala · 2021 · International Journal of Molecular Sciences
  87. Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases
    Ana Isabel Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana S. Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot‐Przeczek, Sentiljana Gumeni et al. · 2024 · Redox Biology
  88. Human iPSC- and Primary-Retinal Pigment Epithelial Cells for Modeling Age-Related Macular Degeneration
    Cody R. Fisher, Mara C. Ebeling, Zhaohui Geng, Rebecca J. Kapphahn, Heidi Roehrich, Sandra Rocio Montezuma, James R. Dutton, Deborah A. Ferrington · 2022 · Antioxidants
  89. Flavoprotein fluorescence elevation is a marker of mitochondrial oxidative stress in patients with retinal disease
    Sofia Ahsanuddin, Hernán Andrés Ríos, Oscar Otero-Marquez, Jason Macanian, Davis B. Zhou, Collin Rich, Richard B. Rosen · 2023 · Frontiers in Ophthalmology
  90. Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells
    Anton Lennikov, Anthony Mukwaya, Madhu Sudhana Saddala, Huang Hu · 2020 · Laboratory Investigation
  91. Genes Involved in Energy Metabolism Are Differentially Expressed During the Day–Night Cycle in Murine Retinal Pigment Epithelium
    Elja Louer, Guoqiang Yi, Claudia Carmone, Joris Robben, Henk G. Stunnenberg, Anneke I. den Hollander, Peter M.T. Deen · 2020 · Investigative Ophthalmology & Visual Science
  92. Location-Specific Thickness Patterns in Intermediate Age-Related Macular Degeneration Reveals Anatomical Differences in Multiple Retinal Layers
    Trinh, Matt, Khou, Vincent, Kalloniatis, Michael, Nivison-Smith, Lisa · 2021 · Investigative Opthalmology & Visual Science
  93. How crosstalk between mitochondria, lysosomes, and other organelles can prevent or promote dry age-related macular degeneration
    Aparna Lakkaraju, Patricia Boya, MARIE E. CSETE, Deborah A. Ferrington, James B. Hurley, Alfredo Arrigo Sadun, Peng Shang, Ruchi Sharma, Debasish Sinha, Marius Ueffing et al. · 2024 · Experimental Eye Research
  94. The role of microRNAs in the pathophysiology of the aging eye
    Mohammadsaber Tamaddon, Mohammadreza Fazel, Delsuz Rezaee, Mohammad Amin Khalilzad, Jamal Majidpoor, Hamid Ahmadieh, Mohammad-Davood Fattahi, Kosar Namakin, Fatemeh Suri, Sajad Najafi · 2025 · Ageing Research Reviews
  95. Differential Expression of Kinin Receptors in Human Wet and Dry Age-Related Macular Degeneration Retinae
    Rahmeh Othman, Simon Berbari, Elvire Vaucher, Réjean Couture · 2020 · Pharmaceuticals
  96. The many faces of SIRT6 in the retina and retinal pigment epithelium
    Jie Cheng, Casey J. Keuthan, Noriko Esumi · 2023 · Frontiers in Cell and Developmental Biology
  97. A Re-Appraisal of Pathogenic Mechanisms Bridging Wet and Dry Age-Related Macular Degeneration Leads to Reconsider a Role for Phytochemicals
    Roberto Pinelli, Francesca Biagioni, Fiona Limanaqi, Miorica Bertelli, Elena Scaffidi, Maico Polzella, Carla Letizia Busceti, Francesco Fornai · 2020 · International Journal of Molecular Sciences
  98. Medical progress: Stem cells as a new therapeutic strategy for COVID-19
    Claudia Musiał, Magdalena Górska‐Ponikowska · 2021 · Stem Cell Research
  99. Cysteinyl leukotriene receptor 1 modulates autophagic activity in retinal pigment epithelial cells
    Andreas Koller, Daniela Bruckner, Ludwig Aigner, Herbert Anton Reitsamer, Andrea Trost · 2020 · Scientific Reports
  100. Inflammasome Activation in Retinal Pigment Epithelium from Human Donors with Age-Related Macular Degeneration
    Mara C. Ebeling, Cody R. Fisher, Rebecca J. Kapphahn, Madilyn R. Stahl, Shichen Shen, Jun Qu, Sandra Rocio Montezuma, Deborah A. Ferrington · 2022 · Cells