Regulatory T cells in cancer immunotherapy
Tanaka, Atsushi, Sakaguchi, Shimon·2017·Cell Research
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- Clinical Implications of Tumor-Infiltrating Immune Cells in Breast CancerShichao Zhang, Zuquan Hu, Jinhua Long, Guiming Zhu, Yun Wang, Yi Jia, Jing Zhou, Yan Ouyang, Zhu Zeng · 2019 · Journal of Cancer
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- Immunogenomics Analysis Reveals that TP53 Mutations Inhibit Tumor Immunity in Gastric CancerZehang Jiang, Zhixian Liu, Mengyuan Li, Cai Chen, Xiaosheng Wang · 2018 · Translational Oncology
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- Immunotherapeutic interventions of Triple Negative Breast CancerZehuan Li, Yiran Qiu, Weiqi Lu, Ying Jiang, Jin Wang · 2018 · Journal of Translational Medicine
- The Tolerogenic Function of Regulatory T Cells in Pregnancy and CancerNanna Jørgensen, Gry Persson, Thomas Vauvert F. Hviid · 2019 · Frontiers in Immunology
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- Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategiesYun Liu, Jianfeng Guo, Leaf Huang · 2020 · Theranostics
- Targeting Tryptophan Catabolism in Cancer Immunotherapy Era: Challenges and PerspectivesFlorent Peyraud, Jean‐Philippe Guégan, D. Bodet, Sophie Cousin, Alban Bessede, Antoîne Italiano · 2022 · Frontiers in Immunology
- Metabolic crosstalk in the tumor microenvironment regulates antitumor immunosuppression and immunotherapy resisitanceFang Wei, Dan Wang, Junyuan Wei, Niwen Tang, Le Min Tang, Fang Xiong, Can Jie Guo, Ming Zhou, Xiaoling Li, Guiyuan Li et al. · 2020 · Cellular and Molecular Life Sciences
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- Virus‐like particles for vaccination against cancerMona Omar Mohsen, Daniel E. Speiser, Alexander K. Knuth, Martin F. Bachmann · 2019 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
- Nanoparticles for tumor immunotherapyXinlong Zang, Xiuli Zhao, Haiyang Hu, Mingxi Qiao, Yihui Deng, Dawei Chen · 2017 · European Journal of Pharmaceutics and Biopharmaceutics
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- Blockade of β-Catenin–Induced CCL28 Suppresses Gastric Cancer Progression via Inhibition of Treg Cell InfiltrationLu Ji, Wei Qian, Liming Gui, Zhongzhong Ji, Pan Yin, Guan Ning Lin, You Wang, Bin Ma, Wei‐Qiang Gao · 2020 · Cancer Research
- A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell FunctionChin-San Loo, Jovylyn Gatchalian, Yuqiong Liang, Mathias Leblanc, Mingjun Xie, Josephine Ho, Bhargav Venkatraghavan, Diana C. Hargreaves, Ye Zheng · 2020 · Immunity
- Intratumoral regulatory T cells: markers, subsets and their impact on anti-tumor immunityYano, Hiroshi, Andrews, Lawrence P., Workman, Creg J., Vignali, Dario A. A. · 2019 · Immunology
- Acute pharmacological degradation of Helios destabilizes regulatory T cellsWang, Eric S., Verano, Alyssa L., Nowak, Radosław P., Yuan, J. Christine, Donovan, Katherine A., Eleuteri, Nicholas A., Yue, Hong, Ngo, Kenneth H., Lizotte, Patrick H., Gokhale, Prafulla C. et al. · 2021 · Nature Chemical Biology
- Recent updates in cancer immunotherapy: a comprehensive review and perspective of the 2018 China Cancer Immunotherapy Workshop in BeijingZihai Li, Wenru Song, Mark P. Rubinstein, Delong Liu · 2018 · Journal of Hematology & Oncology
- Recruitment and Expansion of Tregs Cells in the Tumor Environment—How to Target Them?Justine Cinier, Margaux Hubert, Laurie Besson, Anthony Di Roio, Céline Rodriguez, Vincent Lombardi, Christophe Caux, Christine Ménétrier‐Caux · 2021 · Cancers
- Review of the Immune Checkpoint Inhibitors in the Context of Cancer TreatmentNorah A. Alturki · 2023 · Journal of Clinical Medicine
- Cancer immunotherapy with check point inhibitor can cause autoimmune adverse events due to loss of Treg homeostasisKumar, Prabhakaran, Saini, Shikha, Prabhakar, Bellur S. · 2020 · Seminars in Cancer Biology
- Artemisinin enhances the anti-tumor immune response in 4T1 breast cancer cells in vitro and in vivoYu Qing Cao, Yonghui Feng, Liwei Gao, Xiao-Ying Li, Quanxiu Jin, Yuying Wang, Yingying Xu, Feng Jin, Shi‐Long Lu, Minjie Wei · 2019 · International Immunopharmacology
- Gut microbiota-mediated immunomodulation in tumorLiu, Xinyi, Chen, Yanjie, Zhang, Si, Dong, Ling · 2021 · Journal of Experimental & Clinical Cancer Research
- Nanomedicines modulating tumor immunosuppressive cells to enhance cancer immunotherapyYuefei Zhu, Xiangrong Yu, Soracha Thamphiwatana, Ying Zheng, Zhiqing Pang · 2020 · Acta Pharmaceutica Sinica B
- Tumor microenvironment and immunotherapy of oral cancerChang Xin Liu, Min Wang, Haiyang Zhang, Chunyan Li, Tianshou Zhang, Hong Shi Liu, Song Zhu, Jie Chen · 2022 · European journal of medical research
- CD25 : A potential tumor therapeutic targetYujia Peng, Yiran Tao, Ya Zhang, Jiaxing Wang, Jinliang Yang, Yuxi Wang · 2022 · International Journal of Cancer
- Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMapYacine Bounab, Klaus Eyer, Sophie Dixneuf, Magda Rybczynska, Cécile Chauvel, Maxime Mistretta, Trang Tran, Nathan Aymerich, Guilhem Chenon, Jean‐François Llitjos et al. · 2020 · Nature Protocols
- Regulation of Ovarian Cancer Prognosis by Immune Cells in the Tumor MicroenvironmentMaureen L. Drakes, Patrick J. Stiff · 2018 · Cancers
- Directing Traffic: How to Effectively Drive T Cells into TumorsAnnabelle J. Anandappa, Catherine J. Wu, Patrick Alexander Ott · 2020 · Cancer Discovery
- Ultrasound in tumor immunotherapy: Current status and future developmentsYi-Ju Ho, Ju-Pi Li, Ching‐Hsiang Fan, Hao-Li Liu, Chih‐Kuang Yeh · 2020 · Journal of Controlled Release
- Immunomodulatory potential of natural products from herbal medicines as immune checkpoints inhibitors: Helping to fight against cancer via multiple targetsZhangfeng Zhong, Chi Teng Vong, Feiyu Chen, Horyue Tan, Cheng Zhang, Ning Wang, Liao Cui, Yitao Wang, Yibin Feng · 2022 · Medicinal Research Reviews
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- Metabolic reprogramming and crosstalk of cancer-related fibroblasts and immune cells in the tumor microenvironmentYifei Zhu, Xinyan Li, Lei Wang, Xiwei Hong, Jie Yang · 2022 · Frontiers in Endocrinology
- CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cellsMyung‐Chul Kim, Nicholas C. Borcherding, Kawther Khalid Ahmed, Andrew P. Voigt, Ajaykumar Vishwakarma, Ryan H. Kolb, Paige Kluz, Gaurav Pandey, Umasankar De, Theodore T. Drashansky et al. · 2021 · Nature Communications
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- Exosomes from heat‐stressed tumour cells inhibit tumour growth by converting regulatory T cells to Th17 cells via IL‐6Danfeng Guo, Yinghu Chen, Shoujie Wang, Lei Yu, Yingying Shen, Haijun Zhong, Yunshan Yang · 2017 · Immunology
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- Cancer-associated adipocytes as immunomodulators in cancerWu, Qi, Li, Bei, Li, Juanjuan, Sun, Si, Yuan, Jingping, Sun, Shengrong · 2021 · Biomarker Research
- Dual fluorescence imaging-guided programmed delivery of doxorubicin and CpG nanoparticles to modulate tumor microenvironment for effective chemo-immunotherapyXia Dong, Afeng Yang, Yun Bai, Deling Kong, Feng Lv · 2019 · Biomaterials
- Cancer vaccines: current status and future directionsYi Zhou, Yuquan Wei, Xiaohe Tian, Xiawei Wei · 2025 · Journal of Hematology & Oncology
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- A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCCLaurel B. Darragh, Michael W. Knitz, Junxiao Hu, Eric T. Clambey, Jennifer Backus, Andrew Dumit, Von Samedi, Andrew N. Bubak, Casey S. Greene, Timothy V. Waxweiler et al. · 2022 · Nature Cancer
- Tumor-derived exosomes drive pre-metastatic niche formation in lung via modulating CCL1+ fibroblast and CCR8+ Treg cell interactionsMing Wang, Zhongyu Qin, Yan Yan, Yan Yan, Xixi Duan, Xiaohan Yao, Ziming Jiang, Wenqing Li, Zhihai Qin · 2022 · Cancer Immunology Immunotherapy
- Novel antitumor therapeutic strategy using CD4+ T cell-derived extracellular vesiclesSanghee Shin, Inseong Jung, Dokyung Jung, Christine Seul Ki Kim, Sung‐Min Kang, Suyeon Ryu, Sung-Jin Choi, Soojeong Noh, Jongwon Jeong, Beom Yong Lee et al. · 2022 · Biomaterials
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- Therapeutic Potential of Regulatory T Cells in Preeclampsia—Opportunities and ChallengesSarah Anne Robertson, Ella S. Green, Alison S. Care, Lachlan M. Moldenhauer, Jelmer Riemer Prins, Mary Louise Hull, Simon Charles Barry, Gustaaf Dekker · 2019 · Frontiers in Immunology
- Balancing cancer immunotherapy and immune-related adverse events: The emerging role of regulatory T cellsThemis Alissafi, Aikaterini Hatzioannou, A.I. Legaki, Athina Varveri, Panayotis Verginis · 2019 · Journal of Autoimmunity
- The effects of TNF ‐α/ TNFR2 in regulatory T cells on the microenvironment and progression of gastric cancerYang Qu, Xianhao Wang, Shuai Bai, Liling Niu, Gang Zhao, Yuan Yao, Bin Li, Hui Li · 2021 · International Journal of Cancer
- Medical gas plasma technology: Roadmap on cancer treatment and immunotherapySander Bekeschus · 2023 · Redox Biology
- Therapeutic targeting of DNA methylation alterations in cancerAbigail V. Lee, Kevin A. Nestler, Katherine Bakshian Chiappinelli · 2024 · Pharmacology & Therapeutics
- Tyrosine kinase inhibitor imatinib augments tumor immunity by depleting effector regulatory T cellsTanaka, Atsushi, Nishikawa, Hiroyoshi, Noguchi, Shinsuke, Sugiyama, Daisuke, Morikawa, Hiromasa, Takeuchi, Yoshiko, Ha, Danbee, Shigeta, Naoya, Kitawaki, Toshio, Maeda, Yuka et al. · 2020 · Journal of Experimental Medicine
- Novel TCR-based biologics: mobilising T cells to warm ‘cold’ tumoursKate L. Lowe, David K. Cole, Rupert Kenefeck, Ita OKelly, Marco Lepore, Bent K. Jakobsen · 2019 · Cancer Treatment Reviews
- Significance of CD47 and Its Association With Tumor Immune Microenvironment Heterogeneity in Ovarian CancerLan Yu, Yi Ding, Ting Wan, Ting Deng, He Huang, Jihong Liu · 2021 · Frontiers in Immunology
- aPKC‐ι/P‐Sp1/Snail signaling induces epithelial–mesenchymal transition and immunosuppression in cholangiocarcinomaYawei Qian, Wei Yao, Tao Yang, Yan Yang, Yan Liu, Qi Shen, Jian Zhang, Weipeng Qi, Jianming Wang · 2017 · Hepatology
- Nano-Enhanced Cancer Immunotherapy: Immunology Encounters NanotechnologyErnesto Bockamp, Sebastian Rosigkeit, Dominik Siegl, Detlef Schuppan · 2020 · Cells
- CCR4 Blockade Depletes Regulatory T Cells and Prolongs Survival in a Canine Model of Bladder CancerShingo Maeda, Kohei Murakami, Akiko Inoue, Tomohiro Yonezawa, Naoaki Matsuki · 2019 · Cancer Immunology Research
- Dissecting the Single-Cell Transcriptome Network of Immune Environment Underlying Cervical Premalignant Lesion, Cervical Cancer and Metastatic Lymph NodesChunbo Li, Keqin Hua · 2022 · Frontiers in Immunology
- The Crosstalk between Microbiome and Immune Response in Gastric CancerRihab Nasr, Ali I. Shamseddine, Deborah Mukherji, Farah J. Nassar, Sally Naji Temraz · 2020 · International Journal of Molecular Sciences
- Cancer Vaccines, Treatment of the Future: With Emphasis on HER2-Positive Breast CancerSandeep Pallerla, Ata ur Rahman Mohammed Abdul, Jill M. Comeau, Seetharama D. S. Jois · 2021 · International Journal of Molecular Sciences
- Emerging Role of Circular RNAs in Hepatocellular Carcinoma ImmunotherapyTasneem Abaza, Mostafa K. Abd El‐Aziz, Kerolos Ashraf Daniel, Paraskevi Karousi, Maria Papatsirou, Sherif Ashraf Fahmy, Nadia Μ. Hamdy, Christos K. Kontos, Rana Ahmed Youness · 2023 · International Journal of Molecular Sciences
- TP53 Mutations Promote Immunogenic Activity in Breast CancerZhixian Liu, Zehang Jiang, Yingsheng Gao, Lirui Wang, Cai Chen, Xiaosheng Wang · 2018 · Journal of Oncology
- Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cellsKim, Myeong Joon, Kim, Kyungsoo, Park, Hyo Jin, Kim, Gil-Ran, Hong, Kyeong Hee, Oh, Ji Hoon, Son, Jimin, Park, Dong Jin, Kim, Dahae, Choi, Je-Min et al. · 2023 · Nature Immunology
- APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implicationsYu‐Tzu Tai, Liang Lin, Lijie Xing, Shih‐Feng Cho, Tengteng Yu, Chirag Acharya, Kenneth Wen, Phillip A. Hsieh, John Dulos, Andrea van Elsas et al. · 2018 · Leukemia
- Blocking migration of regulatory T cells to leukemic hematopoietic microenvironment delays disease progression in mouse leukemia modelRong Wang, Wenli Feng, Hao Wang, Lina Wang, Xiao Qi Yang, Feifei Yang, Yingchi Zhang, Xiaoli Liu, Dongyue Zhang, Qian Ren et al. · 2019 · Cancer Letters
- Thymus involution sets the clock of the aging T-cell landscape: Implications for declined immunity and tissue repairYehezqel Elyahu, Alon Monsonego · 2020 · Ageing Research Reviews
- Insight into next-generation CAR therapeutics: designing CAR T cells to improve clinical outcomesEmiliano Roselli, Rawan G. Faramand, Marco L. Davila · 2021 · Journal of Clinical Investigation
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- Immune-Related Adverse Events Due to Cancer Immunotherapy: Immune Mechanisms and Clinical ManifestationsSilvia Casagrande, Giulia Boscato Sopetto, Giovanni Bertalot, Roberto Bortolotti, Vito Racanelli, Orazio Caffo, Bruno Giometto, Alvise Berti, Antonello Veccia · 2024 · Cancers
- AMPK promotes antitumor immunity by downregulating PD-1 in regulatory T cells via the HMGCR/p38 signaling pathwayRam Hari Pokhrel, Suman Acharya, Jae-Hee Ahn, Ye Gu, Mahesh Pandit, Jong‐Oh Kim, Yun‐Yong Park, Ben Kang, Hyun‐Jeong Ko, Jae‐Hoon Chang · 2021 · Molecular Cancer
- The gut microbiome as a target in cancer immunotherapy: opportunities and challenges for drug developmentArielle Elkrief, Reilly Pidgeon, Saman Maleki Vareki, Meriem Messaoudene, Bastien Castagner, Bertrand Routy · 2025 · Nature Reviews Drug Discovery
- Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapyDavid G. Millar, Rakesh R. Ramjiawan, Kosuke Kawaguchi, Nisha Gupta, Chen Jiang, Songfa Zhang, Takashi Nojiri, William W. Ho, Shuichi Aoki, Keehoon Jung et al. · 2020 · Nature Biotechnology
- Targeting tumor-associated macrophages in head and neck squamous cell carcinomaBolei Li, Min Ren, Xuedong Zhou, Qi Han, Lei Cheng · 2020 · Oral Oncology
- Prostaglandin E2 in the Tumor Microenvironment, a Convoluted Affair Mediated by EP Receptors 2 and 4Ana Santiso, Ákos Heinemann, Julia Kargl · 2024 · Pharmacological Reviews
- Treg Destabilization and Reprogramming: Implications for Cancer ImmunotherapyMunn, David H., Sharma, Madhav D., Johnson, Theodore S. · 2018 · Cancer Research
- Breast cancer cells survive chemotherapy by activating targetable immune-modulatory programs characterized by PD-L1 or CD80Ashkan Shahbandi, Fang-Yen Chiu, Nathan Ungerleider, Raegan M. Kvadas, Zeinab Mheidly, Meijuan J.S. Sun, Di Tian, Daniel A. Waizman, Ashlyn Y. Anderson, Heather L. Machado et al. · 2022 · Nature Cancer
- Regulators of CD8+ T cell exhaustionQinli Sun, Chen Dong · 2025 · Nature reviews. Immunology