CoChat
Sign Up
Cited by 9Sexual function and dysfunction studiesSexuality, Behavior, and TechnologyUrological Disorders and Treatments

Changes in sexual inhibition and excitation during PDE5I therapy

Louizos, C C J, McCann, B, Knight, P K·2014·International Journal of Impotence Research
DOI 10.1038/ijir.2013.54
Open this paper in CoChat — free account

Abstract

The aim of this longitudinal study was to assess possible changes in sexual inhibition and excitation (measured using the Sexual Inhibition and Sexual Excitation Scales (SIS/SES)) in men being treated with PDE5 inhibitors (PDE5I) for ED. Established PDE5I users diagnosed with psychogenic ED completed the SES/SIS questionnaire at recruitment and 3 months later. On the basis of International Index of Erectile Function scores at recruitment, subjects were divided into two groups - mildly affected (M) and mild-to-moderately affected (MM). SES scores were significantly lower, and SIS1 scores were significantly higher in Group MM at recruitment and at 3 months (P<0.001). In Group M, SES scores increased (P<0.005) and SIS1 (P<0.001) and SIS2 (P=0.01) scores decreased over the 3 months of the study. In Group MM, ongoing decreases in SES and increases in SIS1 scores were observed (P<0.001). The results of multiple linear regression showed that SIS/SES variables were of little value in predicting erectile function (EF) at recruitment, or changes in EF during the study period. The results for Group M showed that men whose EF scores increased were more likely to experience increased SIS2 and decreased SES scores.

Integrity signals

Registry

Crossref · 10.1038/ijir.2013.54

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Medical treatment is not only indicated for organic ED; PDE5 inhibitors can be used for psychologic ED to reduce failure anxiety and increase self-confidence.

    “Medical treatment is, however, not only indicated in case of organic ED. PDE5 inhibitors, for example, can be used in case of psychologic ED as well to reduce failure anxiety and increase self-confidence as a first step to regain control over their erectile function.113,114”

    From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [113]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Louizos, C. C. J., McCann, B., & Knight, P. K.
Affiliations
The University of Sydney (AU)
Corresponding author
Knight, P K
ORCID
Knight, P K
Venue
International Journal of Impotence Research
Publisher
Springer Science and Business Media LLC
Published
2014-01-23
Volume
26
Issue
4
Pages
146-150
ISSN
  • 0955-9930 (ISSN-L)
  • 1476-5489
DOI
10.1038/ijir.2013.54
OpenAlex
W2060621122
Cited by
9
References
25
Citations by year
2026: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 1 · 2017: 1 · 2015: 1
FWCI
0.51
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • International Journal of Impotence Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
Eli Lilly Australia
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
  • Health Sciences › Medicine › Urology › Urological Disorders and Treatments
Keywords
sexual inhibition, sexual excitation, phosphodiesterase-5 inhibitors, erectile dysfunction, psychogenic erectile dysfunction, erectile function, International Index of Erectile Function
MeSH terms
Adult, Dose-Response Relationship, Drug, Humans, Erectile Dysfunction, Longitudinal Studies, Male, Middle Aged, Penile Erection, Surveys and Questionnaires, Sexual Behavior, Sexual Dysfunctions, Psychological, Phosphodiesterase 5 Inhibitors

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review