p63 in Skin Development and Ectodermal Dysplasias

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

Yang, A., Schweitzer, R., Sun, D., Kaghad, M., Walker, N., Bronson, R. T., Tabin, C. J., Sharpe, A. H., Caput, D., Crum, C. P., et al. (1999) · Nature · doi:10.1038/19539 · Cited by 2,224 · see citing works

p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities

Yang, A., Kaghad, M., Wang, Y., Gillett, E. S., Fleming, M. D., Dötsch, V., Andrews, N. C., Caput, D., & McKeon, F. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80275-0 · Cited by 2,086 · see citing works

p63 is a p53 homologue required for limb and epidermal morphogenesis

Mills, A. A., Zheng, B., Wang, X., Vogel, H. S., Roop, D. R., & Bradley, A. (1999) · Nature · doi:10.1038/19531 · Cited by 1,974 · see citing works

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

Ito, M., Liu, Y., Yang, Z., Nguyen, J., Liang, F., Morris, R. J., & Cotsarelis, G. (2005) · Nature Medicine · doi:10.1038/nm1328 · Cited by 1,317 · see citing works

p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia

Senoo, M., Pinto, F., Crum, C. P., & McKeon, F. (2007) · Cell · doi:10.1016/j.cell.2007.02.045 · Cited by 881 · cited 1× · see citing works

A skin microRNA promotes differentiation by repressing ‘stemness’

Yi, R., Poy, M. N., Stoffel, M., & Fuchs, E. (2008) · Nature · doi:10.1038/nature06642 · Cited by 790 · see citing works

MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis?

Sonkoly, E., Wei, T., Janson, P. C. J., Sääf, A., Lundeberg, L., Tengvall-Linder, M., Norstedt, G., Alenius, H., Homey, B., Scheynius, A., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000610 · Cited by 754 · see citing works

A dermal niche for multipotent adult skin-derived precursor cells

Fernandes, K. J. L., McKenzie, I. A., Mill, P., Smith, K. M., Akhavan, M., Barnabé‐Heider, F., Biernaskie, J. A., Junek, A., Kobayashi, N., Toma, J. G., et al. (2004) · Nature Cell Biology · doi:10.1038/ncb1181 · Cited by 733 · see citing works

Heterozygous Germline Mutations in the p53 Homolog p63 Are the Cause of EEC Syndrome

Celli, J., Duijf, P. H. G., Hamel, B. C. J., Bamshad, M. J., Kramer, B., Smits, A., Newbury-Ecob, R. A., Hennekam, R. C. M., Buggenhout, G. V., van Haeringen, A., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)81646-3 · Cited by 707 · see citing works

p63 is the molecular switch for initiation of an epithelial stratification programPreprint

Koster, M. I., Kim, S., Mills, A. A., DeMayo, F. J., & Roop, D. R. (2004) · Genes & Development · doi:10.1101/gad.1165104 · Cited by 622 · see citing works

Links between signal transduction, transcription and adhesion in epithelial bud development

Jamora, C., DasGupta, R., Kocieniewski, P., & Fuchs, E. V. (2003) · Nature · doi:10.1038/nature01458 · Cited by 567 · see citing works

The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein

Rice, R. H., & Green, H. (1977) · Cell · doi:10.1016/0092-8674(77)90059-9 · Cited by 535 · see citing works

The matrix reorganized: extracellular matrix remodeling and integrin signaling

Larsen, M., Artym, V. V., Green, J. A., & Yamada, K. M. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.08.009 · Cited by 535 · see citing works

Programming gene expression in developing epidermis

Byrne, C. R., Tainsky, M. A., & Fuchs, E. V. (1994) · Development · doi:10.1242/dev.120.9.2369 · Cited by 487 · see citing works

p63 regulates proliferation and differentiation of developmentally mature keratinocytesPreprint

Truong, A. B., Kretz, M., Ridky, T. W., Kimmel, R. A., & Khavari, P. A. (2006) · Genes & Development · doi:10.1101/gad.1463206 · Cited by 480 · see citing works

The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal developmentPreprint

Robledo, R. F., Rajan, L., Li, X., & Lufkin, T. (2002) · Genes & Development · doi:10.1101/gad.988402 · Cited by 420 · see citing works

Strategies of epithelial repair: Modulation of stem cell and transit amplifying cell proliferation

Lehrer, M. S., Sun, T., & Lavker, R. M. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.19.2867 · Cited by 415 · see citing works

p63 regulates an adhesion programme and cell survival in epithelial cells

Carroll, D. K., Carroll, J. S., Leong, C., Cheng, F., Brown, M. A., Mills, A. A., Brugge, J. S., & Ellisen, L. W. (2006) · Nature Cell Biology · doi:10.1038/ncb1420 · Cited by 403 · see citing works

miR-203 represses ‘stemness’ by repressing ΔNp63

Lena, A. M., Shalom-Feuerstein, R., di Val Cervo, P. R., Aberdam, D., Knight, R. A., Melino, G., & Candi, E. (2008) · Cell Death & Differentiation · doi:10.1038/cdd.2008.69 · Cited by 389 · see citing works

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiationPreprint

Nguyen, B.-C., Lefort, K., Mandinova, A., Antonini, D., Devgan, V., Gatta, G. D., Koster, M. I., Zhang, Z., Wang, J., di Vignano, A. T., et al. (2006) · Genes & Development · doi:10.1101/gad.1406006 · Cited by 384 · see citing works

Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63

McGrath, J. A. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.3.221 · Cited by 382 · see citing works

p63 Gene Mutations in EEC Syndrome, Limb-Mammary Syndrome, and Isolated Split Hand–Split Foot Malformation Suggest a Genotype-Phenotype Correlation

van Bokhoven, H., Hamel, B. C. J., Bamshad, M., Sangiorgi, E., Gurrieri, F., Duijf, P. H. G., Vanmolkot, K. R. J., van Beusekom, E., van Beersum, S. E. C., Celli, J., et al. (2001) · The American Journal of Human Genetics · doi:10.1086/323123 · Cited by 372 · see citing works

The ΔNp63α Phosphoprotein Binds the p21 and 14-3-3σ Promoters In Vivo and Has Transcriptional Repressor Activity That Is Reduced by Hay-Wells Syndrome-Derived Mutations

Westfall, M. D., Mays, D. J., Sniezek, J. C., & Pietenpol, J. A. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.7.2264-2276.2003 · Cited by 329 · see citing works

Mechanisms Regulating Epithelial Stratification

Koster, M. I., & Roop, D. R. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123357 · Cited by 324 · see citing works

Formation of cytoskeletal elements during mouse embryogenesis. IV. Ultrastructure of primary mesenchymal cells and their cell-cell interactions.

Franke, W. W., Gründ, C., Jackson, B. W., & Illmensee, K. (1983) · PubMed · Cited by 318 · see citing works

Perp Is a p63-Regulated Gene Essential for Epithelial Integrity

Ihrie, R. A., Marques, M. R., Nguyen, B., Horner, J. S., Papazoglu, C., Bronson, R. T., Mills, A. A., & Attardi, L. D. (2005) · Cell · doi:10.1016/j.cell.2005.01.008 · Cited by 311 · see citing works

Long-term renewal of hair follicles from clonogenic multipotent stem cells

Claudinot, S., Nicolas, M., Oshima, H., Rochat, A., & Barrandon, Y. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507250102 · Cited by 308 · see citing works

p63-Associated Disorders

Rinne, T., Brunner, H. G., & van Bokhoven, H. (2007) · Cell Cycle · doi:10.4161/cc.6.3.3796 · Cited by 290 · see citing works

Split-Hand/Split-Foot Malformation Is Caused by Mutations in the p63 Gene on 3q27

Ianakiev, P., Kilpatrick, M. W., Toudjarska, I., Basel, D., Beighton, P., & Tsipouras, P. (2000) · The American Journal of Human Genetics · doi:10.1086/302972 · Cited by 288 · see citing works

Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein

McGregor, L., Makela, V., Darling, S. M., Vrontou, S., Chalepakis, G., Roberts, C., Smart, N., Rutland, P., Prescott, N. J., Hopkins, J., et al. (2003) · Nature Genetics · doi:10.1038/ng1142 · Cited by 259 · see citing works

TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance

Su, X., Paris, M., Gi, Y. J., Tsai, K. Y., Cho, M. S., Lin, Y.-L., Biernaskie, J., Sinha, S., Prives, C. L., Pevny, L., et al. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.04.003 · Cited by 251 · see citing works

Protein composition of cornified cell envelopes of epidermal keratinocytes

Steven, A. C., & Steinert, P. M. (1994) · Journal of Cell Science · doi:10.1242/jcs.107.2.693 · Cited by 245 · see citing works

Identification of a mutation in DLX3 associated with tricho-dento- osseous (TDO) syndrome

Price, J. A. (1998) · Human Molecular Genetics · doi:10.1093/hmg/7.3.563 · Cited by 240 · see citing works

p63 induces key target genes required for epidermal morphogenesis

Koster, M. I., Dai, D., Marinari, B., Sano, Y., Costanzo, A., Karin, M., & Roop, D. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611376104 · Cited by 234 · see citing works

The E3 ubiquitin ligase Itch controls the protein stability of p63

Rossi, M., Aqeilan, R. I., Neale, M. H., Candi, E., Salomoni, P., Knight, R. A., Croce, C. M., & Melino, G. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603449103 · Cited by 220 · see citing works

Formation of cytoskeletal elements during mouse embryogenesis

Franke, W. W., Gründ, C., Jackson, B. W., & Illmensee, K. (1984) · Differentiation · doi:10.1111/j.1432-0436.1984.tb01348.x · Cited by 218 · see citing works

Down-regulation of p63 is required for epidermal UV-B-induced apoptosis.

Liefer, K. M., Koster, M. I., Wang, X., Yang, A., McKeon, F., & Roop, D. R. (2000) · PubMed · Cited by 211 · see citing works

Pathogenesis of split-hand/split-foot malformation

Duijf, P. H. G. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg090 · Cited by 207 · see citing works

Formation of Cytoskeletal Elements During Mouse Embryogenesis

Jackson, B. W., Gründ, C., Winter, S., Franke, W. W., & Illmensee, K. (1981) · Differentiation · doi:10.1111/j.1432-0436.1981.tb01177.x · Cited by 202 · see citing works

The p63 gene in EEC and other syndromes

Brunner, H. G., Hamel, B. C. J., & van Bokhoven, H. (2002) · Journal of Medical Genetics · doi:10.1136/jmg.39.6.377 · Cited by 179 · see citing works

Finding One's Niche in the Skin

Fuchs, E. V. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.05.001 · Cited by 171 · see citing works

An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

Romano, R., Ortt, K., Birkaya, B. G., Smalley, K., & Sinha, S. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005623 · Cited by 166 · see citing works

Identification and functional characterization of two new transcriptional variants of the human p63 gene

Mangiulli, M., Valletti, A., Caratozzolo, M. F., Tullo, A., Sbisà, E., Pesole, G., & D’Erchia, A. M. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp674 · Cited by 130 · see citing works

Distinct CDH3 mutations cause ectodermal dysplasia, ectrodactyly, macular dystrophy (EEM syndrome)

Kjaer, K. W., Hansen, L., Schwabe, G. C., Marques‐de‐Faria, A. P., Eiberg, H., Mundlos, S., Tommerup, N., & Rosenberg, T. (2005) · Journal of Medical Genetics · doi:10.1136/jmg.2004.027821 · Cited by 125 · see citing works

Physical mapping of the split hand/split foot locus on chromosome 7 and implication in syndromic ectrodactyly

Scherer, S. W., Poorka, P., Massa, H. F., Soder, S., Allen, T., Nuñes, M. E., Geshurl, D., Wong, E., Bellonl, E., Little, S., et al. (1994) · Human Molecular Genetics · doi:10.1093/hmg/3.8.1345 · Cited by 124 · see citing works

P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle

Shimomura, Y., Wajid, M., Shapiro, L., & Christiano, A. M. (2008) · Development · doi:10.1242/dev.006718 · Cited by 122 · see citing works

Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice

Vrontou, S., Petrou, P., Meyer, B. I., Galanopoulos, V. K., Imai, K., Yanagi, M., Chowdhury, K., Scambler, P. J., & Chalepakis, G. (2003) · Nature Genetics · doi:10.1038/ng1168 · Cited by 118 · see citing works

Regulation ofDlx5andDlx6gene expression by p63 is involved in EEC and SHFM congenital limb defects

Iacono, N. L., Mantero, S., Chiarelli, A., Garcia, E., Mills, A. A., Morasso, M. I., Costanzo, A., Levi, G., Guerrini, L., & Merlo, G. R. (2008) · Development · doi:10.1242/dev.011759 · Cited by 112 · see citing works

Mouse model of split hand/foot malformation type I

Merlo, G. R., Paleari, L., Mantero, S., Genova, F., Beverdam, A., Palmisano, G. L., Barbieri, O., & Levi, G. (2002) · genesis · doi:10.1002/gene.10098 · Cited by 104 · see citing works

ΔNp63 Is Essential for Epidermal Commitment of Embryonic Stem Cells

Medawar, A., Virolle, T., Rostagno, P., Divonne, S. B.-D. L. F., Gambaro, K., Rouleau, M., & Aberdam, D. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003441 · Cited by 87 · see citing works

Claudin-1 Is a p63 Target Gene with a Crucial Role in Epithelial Development

Lopardo, T., Iacono, N. L., Marinari, B., Giustizieri, M. L., Cyr, D. G., Merlo, G. R., Crosti, F., Costanzo, A., & Guerrini, L. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002715 · Cited by 85 · see citing works

A Pure Population of Ectodermal Cells Derived from Human Embryonic Stem Cells

Aberdam, É., Barak, E., Rouleau, M., de LaForest, S., Berrih‐Aknin, S., Suter, D. M., Krause, K., Amit, M., Itskovitz‐Eldor, J., & Aberdam, D. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0588 · Cited by 70 · see citing works

Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation

Martinez, L. A., Chen, Y., Fischer, S. M., & Conti, C. J. (1999) · Oncogene · doi:10.1038/sj.onc.1202300 · Cited by 69 · see citing works

Rescue of key features of the p63‐null epithelial phenotype by inactivation of Ink4a and Arf

Su, X., Cho, M. S., Gi, Y. J., Ayanga, B. A., Sherr, C. J., & Flores, E. R. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.151 · Cited by 69 · see citing works

Dermatologic findings of ankyloblepharon‐ectodermal defects‐cleft lip/palate (AEC) syndrome

Julapalli, M. R., Scher, R. K., Sybert, V. P., Siegfried, E. C., & Bree, A. F. (2009) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32797 · Cited by 67 · see citing works

p51/p63 Controls Subunit α3 of the Major Epidermis Integrin Anchoring the Stem Cells to the Niche

Kurata, S., Okuyama, T., Osada, M., Watanabe, T., Tomimori, Y., Sato, S., Iwai, A., Tsuji, T., Ikawa, Y., & Katoh, I. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406322200 · Cited by 67 · see citing works

A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes

Rinne, T., Clements, S. E., Lamme, E. N., Duijf, P. H. G., Bolat, E., Meijer, R. P. P., Scheffer, H., Rosser, E. M., Tan, T. Y., McGrath, J. A., et al. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn094 · Cited by 62 · see citing works

Unique domain functions of p63 isotypes that differentially regulate distinct aspects of epidermal homeostasis

King, K. E., Ponnamperuma, R. M., Gerdes, M. J., Tokino, T., YAMASHITA, T., Baker, C. C., & Weinberg, W. C. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi200 · Cited by 58 · see citing works

Homeobox geneDlx3is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias

Radoja, N., Guerrini, L., Iacono, N. L., Merlo, G. R., Costanzo, A., Weinberg, W. C., Mantia, G. L., Calabrò, V., & Morasso, M. I. (2006) · Development · doi:10.1242/dev.02703 · Cited by 55 · see citing works

Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63

Testoni, B. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkj477 · Cited by 54 · see citing works

In Vivo Function of Desmosomes

Cheng, X., & Koch, P. J. (2004) · The Journal of Dermatology · doi:10.1111/j.1346-8138.2004.tb00654.x · Cited by 54 · see citing works

p63 Suppresses Non-epidermal Lineage Markers in a Bone Morphogenetic Protein-dependent Manner via Repression of Smad7

Rosa, L. D., Antonini, D., Ferone, G., Russo, M. T., Yu, P. B., Han, R., & Missero, C. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.049619 · Cited by 47 · see citing works

The Fatty Acid Synthase Gene is a Conserved p53 Family Target Gene from Worm to Human

D’Erchia, A. M., Tullo, A., Lefkimmiatis, K., Saccone, C., & Sbisà, E. (2006) · Cell Cycle · doi:10.4161/cc.5.7.2622 · Cited by 46 · see citing works

IKKα Is a p63 Transcriptional Target Involved in the Pathogenesis of Ectodermal Dysplasias

Marinari, B., Ballarò, C., Koster, M. I., Giustizieri, M. L., Moretti, F., Crosti, F., Papoutsaki, M., Karin, M., Alemà, S., Chimenti, S., et al. (2008) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.202 · Cited by 46 · see citing works

ΔNp63 knockdown mice: A mouse model for AEC syndrome

Koster, M. I., Marinari, B., Payne, A. S., Kantaputra, P. N., Costanzo, A., & Roop, D. R. (2009) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32794 · Cited by 44 · see citing works

Regulation of the Cyclin-Dependent Kinase Inhibitor p57Kip2 Expression by p63

Beretta, C., Chiarelli, A., Testoni, B., Mantovani, R., & Guerrini, L. (2005) · Cell Cycle · doi:10.4161/cc.4.11.2135 · Cited by 44 · see citing works

Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation

Costanzo, A. D., Festa, L., Duverger, O., Vivo, M., Guerrini, L., Mantia, G. L., Morasso, M. I., & Calabrò, V. (2009) · Cell Cycle · doi:10.4161/cc.8.8.8202 · Cited by 44 · see citing works

Molecular Consequences of a Frameshifted DLX3 Mutant Leading to Tricho-Dento-Osseous Syndrome

Duverger, O., Lee, D., Hassan, M. Q., Chen, S. X., Jaisser, F., Lian, J. B., & Morasso, M. I. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709562200 · Cited by 44 · see citing works

Two Novel TP63 Mutations Associated With the Ankyloblepharon, Ectodermal Defects, and Cleft Lip and Palate Syndrome

Payne, A. S., Yan, A. C., Ilyas, E. N., Li, W., Seykora, J. T., Young, T. L., Pawel, B., Honig, P. J., Camacho, J., Imaizumi, S. O., et al. (2005) · Archives of Dermatology · doi:10.1001/archderm.141.12.1567 · Cited by 41 · see citing works

Correlated alterations in prostate basal cell layer and basement membrane

Liu, A., Wei, L., Gardner, W. A., Deng, C., & Man, Y. (2009) · International Journal of Biological Sciences · doi:10.7150/ijbs.5.276 · Cited by 39 · see citing works

p63/p51-induced Onset of Keratinocyte Differentiation via the c-Jun N-terminal Kinase Pathway Is Counteracted by Keratinocyte Growth Factor

Ogawa, E., Okuyama, R., Egawa, T., Nagoshi, H., Obinata, M., Tagami, H., Ikawa, S., & Aiba, S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m804101200 · Cited by 39 · see citing works

p73 and p63 Sustain Cellular Growth by Transcriptional Activation of Cell Cycle Progression Genes

Lefkimmiatis, K., Caratozzolo, M. F., Merlo, P., D’Erchia, A. M., Navarro, B., Levrero, M., Sbisà, E., & Tullo, A. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0259 · Cited by 39 · see citing works

Cdh1 controls the stability of TACC3

Jeng, J., Lin, Y.-M., Lin, C.-H., & Shih, H. (2009) · Cell Cycle · doi:10.4161/cc.8.21.9935 · Cited by 34 · see citing works

Downregulation of ΔNp63α in keratinocytes by p14ARF-mediated SUMO-conjugation and degradation

Vivo, M., Costanzo, A. D., Fortugno, P., Pollice, A., Calabrò, V., & Mantia, G. L. (2009) · Cell Cycle · doi:10.4161/cc.8.21.9954 · Cited by 34 · see citing works

Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis

Beaudry, V. G., Pathak, N., Koster, M. I., & Attardi, L. D. (2009) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32760 · Cited by 31 · see citing works

p63 directly induces expression of Alox12, a regulator of epidermal barrier formation

Kim, S., Choi, I. F., Quante, J. R., Zhang, L., Roop, D. R., & Koster, M. I. (2009) · Experimental Dermatology · doi:10.1111/j.1600-0625.2009.00894.x · Cited by 31 · see citing works

Craniofacial and anthropometric phenotype in ankyloblepharon–ectodermal defects–cleft lip/palate syndrome (Hay–Wells syndrome) in a cohort of 17 patients

Sutton, V. R., Plunkett, K., Dang, D. X., Lewis, R. A., Bree, A. F., & Bacino, C. A. (2009) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32791 · Cited by 31 · see citing works

Connecting p63 to Cellular Proliferation: The Example of the Adenosine Deaminase Target Gene

Sbisà, E., Mastropasqua, G., Lefkimmiatis, K., Caratozzolo, M. F., D’Erchia, A. M., & Tullo, A. (2005) · Cell Cycle · doi:10.4161/cc.5.2.2361 · Cited by 29 · see citing works

Clinical lessons learned from the International Research Symposium on ankyloblepharon‐ectodermal defects‐cleft lip/palate (AEC) syndrome

Bree, A. F. (2009) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32788 · Cited by 8 · see citing works

Dental Enamel Formation and Implications for Oral Health and Disease

Lacruz, R. S., Habelitz, S., Wright, J. T., & Paine, M. L. (2017) · Physiological Reviews · doi:10.1152/physrev.00030.2016 · Cited by 610 · see citing works

Hdac1 and Hdac2 Act Redundantly to Control p63 and p53 Functions in Epidermal Progenitor Cells

LeBoeuf, M. R., Terrell, A. M., Trivedi, S., Sinha, S., Epstein, J. A., Olson, E. N., Morrisey, E. E., & Millar, S. E. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.10.015 · Cited by 246 · see citing works

ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation

Sen, G. L., Boxer, L. D., Webster, D. E., Bussat, R. T., Qu, K., Zarnegar, B. J., Johnston, D., Siprashvili, Z., & Khavari, P. A. (2012) · Developmental Cell · doi:10.1016/j.devcel.2011.12.001 · Cited by 246 · see citing works

ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis

Saladi, S. V., Ross, K. N., Karaayvaz, M., Tata, P. R., Mou, H., Rajagopal, J., Ramaswamy, S., & Ellisen, L. W. (2016) · Cancer Cell · doi:10.1016/j.ccell.2016.12.001 · Cited by 195 · see citing works

Ectodermal dysplasias: Classification and organization by phenotype, genotype and molecular pathway.

Wright, J. T., Fete, M., Schneider, H., Zinser, M., Koster, M. I., Clarke, A. J., Hadj‐Rabia, S., Tadini, G., Pagnan, N., Visinoni, A. F., et al. (2019) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.61045 · Cited by 185 · see citing works

Genetic pathways in disorders of epidermal differentiation

Lopez-Pajares, V., Yan, K., Zarnegar, B. J., Jameson, K. L., & Khavari, P. A. (2012) · Trends in Genetics · doi:10.1016/j.tig.2012.10.005 · Cited by 113 · see citing works

The Molecular Basis of Hereditary Enamel Defects in Humans

Wright, J. T., Carrion, I. A., & Morris, C. (2014) · Journal of Dental Research · doi:10.1177/0022034514556708 · Cited by 110 · see citing works

Sweat gland organoids contribute to cutaneous wound healing and sweat gland regeneration

Diao, J., Liu, J., Wang, S., Chang, M., Wang, X., Guo, B., Yu, Q., Yan, F., Su, Y., & Wang, Y. (2019) · Cell Death & Disease · doi:10.1038/s41419-019-1485-5 · Cited by 92 · see citing works

The histone methyltransferase Setd8 acts in concert with c‐Myc and is required to maintain skin

Driskell, I. M., Oda, H., Blanco, S., Nascimento, E. M., Humphreys, P. D., & Frye, M. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.421 · Cited by 91 · see citing works

Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer

Blanden, A. R., Yu, X., Loh, S. N., Levine, A. J., & Carpizo, D. R. (2015) · Drug Discovery Today · doi:10.1016/j.drudis.2015.07.006 · Cited by 83 · see citing works

Histone deacetylase 2 controls p53 and is a critical factor in tumorigenesis

Wagner, T., Brand, P., Heinzel, T., & Krämer, O. H. (2014) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2014.07.010 · Cited by 84 · see citing works

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome

Ferone, G., Mollo, M. R., Thomason, H. A., Antonini, D., Zhou, H., Ambrosio, R., Rosa, L. D., Salvatore, D., Getsios, S., van Bokhoven, H., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds464 · Cited by 79 · see citing works

Notch signaling represses p63 expression in the developing surface ectoderm

Tadeu, A. M. B., & Horsley, V. (2013) · Development · doi:10.1242/dev.093948 · Cited by 72 · see citing works

Etiology and pathogenesis of ectodermal dysplasias

Itin, P. H. (2014) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36550 · Cited by 69 · see citing works

Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage

Freije, A., Molinuevo, R., Ceballos, L., Cagigas, M., Alonso‐Lecue, P., Rodrı́guez, R., Menéndez, P. R., Aberdam, D., de Diego, E., & Gandarillas, A. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.10.012 · Cited by 62 · see citing works

Molecular Pathway-Based Classification of Ectodermal Dysplasias: First Five-Yearly Update

Peschel, N., Wright, J. T., Koster, M. I., Clarke, A. J., Tadini, G., Fete, M., Hadj-Rabia, S., Sybert, V. P., Norderyd, J., Maier-Wohlfart, S., et al. (2022) · Genes · doi:10.3390/genes13122327 · Cited by 60 · see citing works

Regulation of skin aging and heart development by TAp63

Paris, M., Rouleau, M., Pucéat, M., & Aberdam, D. (2011) · Cell Death and Differentiation · doi:10.1038/cdd.2011.181 · Cited by 54 · see citing works

Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis

Peled, A., Sarig, O., Samuelov, L., Bertolini, M., Ziv, L., Weissglas-Volkov, D., Eskin-Schwartz, M., Adase, C. A., Malchin, N., Bochner, R., et al. (2016) · PLOS Genetics · doi:10.1371/journal.pgen.1006369 · Cited by 55 · see citing works

Novel missense mutation of the TP63 gene in a newborn with Hay-Wells/Ankyloblepharon-Ectodermal defects-Cleft lip/palate (AEC) syndrome: clinical report and follow-up

Serra, G., Antona, V., Giuffrè, M., Pomi, F. L., Scalzo, L. L., Piro, E., Schierz, I. A. M., & Corsello, G. (2021) · The Italian Journal of Pediatrics/Italian journal of pediatrics · doi:10.1186/s13052-021-01152-y · Cited by 43 · see citing works

The Desmosomal Protein Desmoglein 1 Aids Recovery of Epidermal Differentiation after Acute UV Light Exposure

Johnson, J. L., Koetsier, J. L., Sirico, A., Agidi, A. T., Antonini, D., Missero, C., & Green, K. J. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.124 · Cited by 39 · see citing works

The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site.

Orzol, P., Holčáková, J., Nekulová, M., Nenutil, R., Vojtěšek, B., & Coates, P. J. (2015) · PubMed · doi:10.14670/hh-30.503 · Cited by 39 · see citing works

KDF1, encoding keratinocyte differentiation factor 1, is mutated in a multigenerational family with ectodermal dysplasia

Shamseldin, H. E., Khalifa, O. A., Binamer, Y., Almutawa, A., Arold, S. T., Zaidan, H., & Alkuraya, F. S. (2016) · Human Genetics · doi:10.1007/s00439-016-1741-z · Cited by 34 · see citing works

Loss of TP63 Promotes the Metastasis of Head and Neck Squamous Cell Carcinoma by Activating MAPK and STAT3 Signaling

Lakshmanachetty, S., Balaiya, V., High, W. A., & Koster, M. I. (2019) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-18-1355 · Cited by 34 · see citing works

Tp63 in Oral Development, Neoplasia, and Autoimmunity

Romano, R., Solomon, L. W., & Sinha, S. (2011) · Journal of Dental Research · doi:10.1177/0022034511411302 · Cited by 29 · see citing works

Efficient Wound Healing Using a Synthetic Nanofibrous Bilayer Skin Substitute in Murine Model

Arasteh, S., Khanjani, S., Golshahi, H., Mobini, S., Taghizadeh-Jahed, M., Heidari‐Vala, H., Edalatkhah, H., & Kazemnejad, S. (2019) · Journal of Surgical Research · doi:10.1016/j.jss.2019.07.017 · Cited by 29 · see citing works

Identification of chronological and photoageing-associated microRNAs in human skin

Srivastava, A., Karlsson, M. G., Marionnet, C., Bernerd, F., Guéniche, A., Rawadi, C. E., Ståhle, M., Sonkoly, E., Breton, L., & Pivarcsi, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-31217-8 · Cited by 28 · see citing works

HPV8 Field Cancerization in a Transgenic Mouse Model Is due to Lrig1+ Keratinocyte Stem Cell Expansion

Lanfredini, S., Olivero, C., Borgogna, C., Calati, F., Powell, K., Davies, K.-J., Andrea, M. D., Harries, S., Tang, H. K. C., Pfister, H., et al. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2017.04.039 · Cited by 26 · see citing works

Equine Epidermis: A Source of Epithelial-Like Stem/Progenitor Cells with In Vitro and In Vivo Regenerative Capacities

Broeckx, S. Y., Maes, S., Martinello, T., Aerts, D., Chiers, K., Mariën, T., Patruno, M., Franco‐Obregón, A., & Spaas, J. H. (2013) · Stem Cells and Development · doi:10.1089/scd.2013.0203 · Cited by 25 · see citing works

Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility

Lamparter, D., Marbach, D., Rueedi, R., Bergmann, S., & Kutalik, Z. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005311 · Cited by 23 · see citing works

Gene Mutations of the Three Ectodysplasin Pathway Key Players (EDA, EDAR, and EDARADD) Account for More than 60% of Egyptian Ectodermal Dysplasia: A Report of Seven Novel Mutations

Ahmed, H. A., El‐Kamah, G. Y., Rabie, E., Mostafa, M. I., Abouzaid, M. R., Hassib, N. F., Mehrez, M., Kader, M. A., Mohsen, Y. H., Zada, S. K., et al. (2021) · Genes · doi:10.3390/genes12091389 · Cited by 24 · see citing works

Retinoic acid signalling in the development of the epidermis, the limbs and the secondary palate

Mammadova, A., Zhou, H., Carels, C. E. L., & den Hoff, J. W. V. (2016) · Differentiation · doi:10.1016/j.diff.2016.05.001 · Cited by 23 · see citing works

The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells

Suzuki, D., Sahu, R., Leu, N. A., & Senoo, M. (2014) · Development · doi:10.1242/dev.118307 · Cited by 22 · see citing works

OxymiRs in cutaneous development, wound repair and regeneration

Sen, C. K., & Roy, S. (2012) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2012.09.012 · Cited by 21 · see citing works

RNA-seq Studies Reveal New Insights into p63 and the Transcriptomic Landscape of the Mouse Skin

Rizzo, J. M., Romano, R., Bard, J., & Sinha, S. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.384 · Cited by 21 · see citing works

Identification of p63+ keratinocyte progenitor cells in circulation and their matrix-directed differentiation to epithelial cells

Nair, R. P., & Krishnan, L. K. (2013) · Stem Cell Research & Therapy · doi:10.1186/scrt186 · Cited by 21 · see citing works

Y‐box Binding Protein‐1 Is Part of a Complex Molecular Network Linking ΔNp63α to the PI3K/akt Pathway in Cutaneous Squamous Cell Carcinoma

Troiano, A., Lomoriello, I. S., di Martino, O., Fusco, S., Pollice, A., Vivo, M., Mantia, G. L., & Calabrò, V. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.24934 · Cited by 20 · see citing works

Transcriptional Profiling of Ectoderm Specification to Keratinocyte Fate in Human Embryonic Stem Cells

Tadeu, A. M. B., Lin, S. Y., Hou, L., Chung, L. M., Zhong, M., Zhao, H., & Horsley, V. (2015) · PLoS ONE · doi:10.1371/journal.pone.0122493 · Cited by 21 · see citing works

Using paracrine effects of Ad-MSCs on keratinocyte cultivation and fabrication of epidermal sheets for improving clinical applications

Hassanzadeh, H., Matin, M. M., Naderi‐Meshkin, H., Bidkhori, H. R., Mirahmadi, M., Raeesolmohaddeseen, M., Moussavi, N. S., & Bahrami, A. R. (2018) · Cell and Tissue Banking · doi:10.1007/s10561-018-9702-5 · Cited by 20 · see citing works

Modeling AEC—New approaches to study rare genetic disorders

Koch, P. J., Dinella, J., Fete, M. D., Siegfried, E. C., & Koster, M. I. (2014) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36455 · Cited by 19 · see citing works

The apical ectodermal ridge of the mouse model of ectrodactylyDlx5;Dlx6−/−shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand

Conte, D., Garaffo, G., Iacono, N. L., Mantero, S., Piccolo, S., Cordenonsi, M., Pérez-Morga, D. L., Orecchia, V., Poli, V., & Merlo, G. R. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv514 · Cited by 19 · see citing works

Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination

Adam, L., Tchitchek, N., Todorova, B., Rosenbaum, P., Joly, C., Poux, C., Chapon, C., Spetz, A., Ustav, M., Grand, R. L., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1900517 · Cited by 19 · see citing works

Integration of the Transcription Factor-Regulated and Epigenetic Mechanisms in the Control of Keratinocyte Differentiation

Botchkarev, V. A. (2015) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/jidsymp.2015.37 · Cited by 17 · see citing works

β-HPV Infection Correlates with Early Stages of Carcinogenesis in Skin Tumors and Patient-Derived Xenografts from a Kidney Transplant Recipient Cohort

Borgogna, C., Olivero, C., Lanfredini, S., Calati, F., Andrea, M. D., Zavattaro, E., Savoia, P., Trisolini, E., Boldorini, R. L., Patel, G. K., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00117 · Cited by 16 · see citing works

Structure and Function of the Skin

McGrath, J. A., & Uitto, J. (2016) · Wiley eBooks · doi:10.1002/9781118441213.rtd0002 · Cited by 15 · see citing works

Rare Genetic Disorders: Novel Treatment Strategies and Insights Into Human Biology

Koch, P. J., & Koster, M. I. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.714764 · Cited by 14 · see citing works

Mutation in SAM domain of TP63 is associated with nonsyndromic cleft lip and palate and cleft palate

Kantaputra, P. N., Malaivijitnond, S., Vieira, A. R., Heering, J., Dötsch, V., Khankasikum, T., & Sripathomsawat, W. (2011) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.34011 · Cited by 13 · see citing works

New Perspectives in the Pharmacological Treatment of Non-Melanoma Skin Cancer

Savoia, P., Cremona, O., & Fava, P. (2015) · Current Drug Targets · doi:10.2174/1389450116666150806123717 · Cited by 13 · see citing works

The histone acetyltransferase inhibitor Nir regulates epidermis development

Duteil, D., Tourrette, Y., Eberlin, A., Willmann, D., Patel, D., Friedrichs, N., Müller, J. M., & Schüle, R. (2018) · Development · doi:10.1242/dev.158543 · Cited by 13 · see citing works

Embryology and Anatomy of the Skin

Falco, M. D., Pisano, M. M., & Luca, A. D. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7357-2_1 · Cited by 13 · see citing works

Adherens Junctions in Mammalian Development, Homeostasis and Disease: Lessons from Mice

Boggetti, B., & Niessen, C. M. (2012) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-007-4186-7_14 · Cited by 10 · see citing works

Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial Stem Cells and Keratinocytes

Liu, L., Zheng, D., Xu, Z.-F., Zhou, H.-C., Wang, Y.-C., Zhou, H., Ge, J.-Y., Sako, D., Li, M., Akimoto, K., et al. (2021) · Cells · doi:10.3390/cells11010070 · Cited by 10 · see citing works

Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation

Alkhatib, D. Z. R., Truong, T. T. K., Fujii, S., Hasegawa, K., Nagano, R., Tajiri, Y., & Kiyoshima, T. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.154493 · Cited by 10 · see citing works

Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis

Shue, Y. T., Lee, K. T., Walters, B. W., Ong, Y. H. B., Silvaraju, S., Lam, W. J., & Lim, C. Y. (2020) · Epigenetics · doi:10.1080/15592294.2020.1738028 · Cited by 11 · see citing works

Dynamic life of a skin keratinocyte: an intimate tryst with the master regulator p63.

Romano, R., & Sinha, S. (2011) · PubMed · Cited by 9 · see citing works

Integrating Animal Models and In Vitro Tissue Models to Elucidate the Role of Desmosomal Proteins in Diseases

Koster, M. I., Dinella, J., Chen, J., O’Shea, C., & Koch, P. J. (2014) · Cell Communication & Adhesion · doi:10.3109/15419061.2013.876015 · Cited by 9 · see citing works

Perimatrix of middle ear cholesteatoma: A granulation tissue with a specific transcriptomic signature

Jovanović, I. B., Živković, M., Djurić, T., Stojković, L., Jesic, S. D., & Stanković, A. (2019) · The Laryngoscope · doi:10.1002/lary.28084 · Cited by 9 · see citing works

Effects of TP63 mutations on keratinocyte adhesion and migration

Salois, M. N., Gugger, J. A., Webb, S., Sheldon, C. E., Parraga, S. P., Lewitt, G. M., Grange, D. K., Koch, P. J., & Koster, M. I. (2023) · Experimental Dermatology · doi:10.1111/exd.14885 · Cited by 7 · see citing works

Innovative Therapeutic Approaches for the Treatment of the Ocular Morbidities in Patients with EEC Syndrome

Barbaro, V., Bonelli, F., Ferrari, S., Vella, G. L., & Iorio, E. D. (2023) · Cells · doi:10.3390/cells12030495 · Cited by 7 · see citing works

Evaluation of Dermal Substitute in a Novel Co-Transplantation Model with Autologous Epidermal Sheet

Huang, G., Ji, S., Luo, P., Zhang, Y., Wang, G., Zhu, S., Xiao, S., & Xia, Z. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049448 · Cited by 7 · see citing works

Structure and Development of the Skin and Cutaneous Appendages

Chu, D. H., & Loomis, C. A. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-3479-7.10061-8 · Cited by 7 · see citing works

Identification of altered protein abundances in cholesteatoma matrix via mass spectrometry-based proteomic analysis

Randall, D. R., Park, P. S., & Chau, J. K. (2015) · Journal of Otolaryngology - Head and Neck Surgery · doi:10.1186/s40463-015-0104-4 · Cited by 6 · see citing works

Ectrodactyly-ectodermal dysplasia-clefting syndrome with unusual cutaneous vitiligoid and psoriasiform lesions due to a novel single point TP63 gene mutation

Wawrzycki, B., Pietrzak, A., Chodorowska, G., Filip, A. A., Petit, V., Rudnicka, L., Dybiec, E., Rakowska, A., Sobczyńska‐Tomaszewska, A., & Kanitakis, J. (2018) · Advances in Dermatology and Allergology · doi:10.5114/ada.2018.73437 · Cited by 6 · see citing works

Effects of retinoic acid on proliferation and gene expression of cleft and non-cleft palatal keratinocytes

Mammadova, A., Ackermans, M. M., Bloemen, M., Oostendorp, C., Zhou, H., Carels, C. E. L., & den Hoff, J. W. V. (2014) · European Journal of Orthodontics · doi:10.1093/ejo/cjt104 · Cited by 6 · see citing works

A Mutation in TP63 Causing a Mild Ectodermal Dysplasia Phenotype

Goldsmith, T., Eytan, O., Magal, L., Solomon, M., Israeli, S., Warshauer, E. M., Grafi‐Cohen, M., Aberdam, D., van Bokhoven, H., Zhou, H., et al. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.159 · Cited by 5 · see citing works

Pathology, Chemoprevention, and Preclinical Models for Target Validation in Barrett Esophagus

Urbanska, A. M., Ponnazhagan, S., & Mozafari, M. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-0206 · Cited by 4 · see citing works

P63 - an important player in epidermal and tumour development.

Orzol, P., Nekulová, M., Vojtěšek, B., & Holčáková, J. (2012) · PubMed · Cited by 4 · see citing works

CDK12 Is Necessary to Promote Epidermal Differentiation Through Transcription Elongation

Li, J., Tiwari, M., Chen, Y., Luanpitpong, S., & Sen, G. L. (2022) · Stem Cells · doi:10.1093/stmcls/sxac002 · Cited by 3 · see citing works

ΔNp63 regulates Sfrp1 expression to direct salivary gland branching morphogenesis

Wrynn, T., Min, S., Horeth, E., Osinski, J. M., Sinha, S., & Romano, R. (2024) · PLoS ONE · doi:10.1371/journal.pone.0301082 · Cited by 2 · see citing works

The involvement of Elf5 in regulating keratinocyte proliferation and differentiation processes in skin

Hu, A., Pickup, M. E., Lawal, M. A., Patel, H. J., & Ahmed, M. I. (2025) · PLoS ONE · doi:10.1371/journal.pone.0316134 · Cited by 2 · see citing works

Developmental Defects of Enamel ☆

Wright, J. T. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64138-7 · Cited by 2 · see citing works

Mosaic TP63 variant and associated ectodermal dysplasia features

Chen, V., Issa, N. T., & Schmidt, F. B. (2021) · JAAD Case Reports · doi:10.1016/j.jdcr.2021.09.016 · Cited by 1 · see citing works

Immunohistochemical and Histopathological Characterization of Spina Bifida Defect Tissues Removed After Prenatal and Postnatal Surgical Repair

Bardill, J. R., Laughter, M. R., Anderson, J. B., Hoffman, H., Gilani, A., Koster, M. I., & Marwan, A. I. (2024) · Fetal and Pediatric Pathology · doi:10.1080/15513815.2024.2326834 · Cited by 1 · see citing works

Hay-Wells syndrome: the challenges of a nine-year follow-up

de Amorim, R. P., Nakata, M. V. Y. M., Gonçalves, V. G. D. P., Martins, I. M. D. C., Haddad, G. R., & Abbade, L. P. F. (2024) · Anais Brasileiros de Dermatologia · doi:10.1016/j.abd.2023.09.012 · Cited by 1 · see citing works

MiR-125b-5p promotes pemphigus vulgaris pathogenesis by modulating desmosome structures

He, W., Xiao, T., Hua, H., Xing, Y., Shang, P., Fu, J., Zheng, L. W., & Wei, P. (2026) · Bioscience Reports · doi:10.1042/bsr20260220 · Cited by 1 · see citing works

Structure and Development of the Skin and Cutaneous Appendages

Chu, D. H., & Loomis, C. A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-35214-7.00048-2 · Cited by 1 · see citing works

Ectodermal Dysplasias

Itin, P. H. (2016) · Wiley eBooks · doi:10.1002/9781118441213.rtd0068 · Cited by 1 · see citing works

Single-cell transcriptomics uncover conserved molecular mechanisms and functional diversification in multilayered epitheliaPreprint

Merle, C., Huyghe, M., Kimber, E., Faraldo, M. M., Pantalacci, S., Sémon, M., Fré, S., & Journot, R. P. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.14.688286 · Cited by 1 · see citing works

The Desmosomal Protein Desmoglein 1 Aids Recovery of Epidermal Differentiation after Acute UV Light

Johnson, E. L., Koetsier, J. L., Sirico, A., Agidi, A. T., Antonini, D., & Green, K. J. (2014)

Molecular Mechanisms of p63-Derived Ectodermal Dysplasia

Lustig, D. G. (2012) · TSpace (University of Toronto)

Genome- wide뀀Ƞassociation뀀Ƞbetween뀀Ƞtranscription뀀Ƞfactor뀀Ƞ expression뀀Ƞand뀀Ƞchromatin뀀Ƞaccessibility뀀Ƞreveals뀀Ƞchromatin뀀Ƞ state뀀Ƞregulators 뀀Ƞ

Lamparter, D., Marbach, D., Rueedi, R., Bergmann, S., & Kutalik, Z. (2016)

Ectodermal Dysplasia: Rapp-Hodgkin Syndrome and Hay-Wells Syndrome

Supsrisunjai, C., & McGrath, J. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65406-5

Environmental Influences on the Development of Epidermal Progenitors

Kogut, I., & Bilousova, G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65469-7

All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

Botchkarev, V. A., Sharov, A. A., & Fessing, M. Y. (2018) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-319-16769-5_1

Human hereditary enamelabnormalities – molecular factors and genetic counselling

Kozma, A., Forna, D. A., Radoi, V. E., Ursu, R., Lackner, A. K., Bohîlțea, L. C., & Lăzărescu, H. (2019) · Romanian Journal of Stomatology · doi:10.37897/rjs.2019.2.1

Il neonato con gli occhi socchiusi. La displasia ectodermica legata al gene TP63

Schierz, I. A. M., & Corsello, G. (2021) · Medico e Bambino - Pagine Elettroniche · doi:10.53126/mebxxiv101

Faculty Opinions recommendation of p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.

Payne, A. S. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717962803.793464815

Oral Cancer

Saladi, S. V., & Ellisen, L. W. (2015) · Springer eBooks · doi:10.1007/978-3-319-17942-1_13

Skin structure

Barker, A. (2015) · doi:10.1002/9781118655412.ch8

A Maverick Review of Common Stem/Progenitor Markers in Lung Development

Lin, Y., Wang, D., & Zeng, Y. (2022) · Stem Cell Reviews and Reports · doi:10.1007/s12015-022-10422-z

A TP63 mutation identified in a Han Chinese family with ectodermal dysplasia

Zhou, X. Y., Zhang, C., Fan, L., Wu, S., Yao, S., Wang, L., Zhong, W., Ma, L., & Pan, Y. (2023) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2023.105731

In vitro analyses of CD4-protein function in dedifferentiated keratinocyte cell lines

Hristomanova, S. (2023) · doi:10.53846/goediss-10088

Ectodermal Dysplasias

Itin, P. H. (2024) · Wiley eBooks · doi:10.1002/9781119709268.rook065

What Is and Isn’t an Ectodermal Dysplasia?

Peschel, N., & Schneider, H. (2024) · Springer eBooks · doi:10.1007/978-3-031-75790-7_2

Selected Hereditary Diseases

Siegel, D. H., Martin, K. L., & Hand, J. L. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-2638-7.00029-8

Complex Wounds in Ectodermal Dysplasias: Translating Discovery to Therapy

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