Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

Akinc, Akin, Querbes, William, De, Soma, Qin, June, Frank-Kamenetsky, Maria, Jayaprakash, K. Narayanannair, Jayaraman, Muthusamy, Rajeev, Kallanthottathil G +17 more·2010·Molecular Therapy

DOI 10.1038/mt.2010.85

Cited by (1,002)

Items 801–900 of 1,002

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Cristina Muntean, Eva Blondeel, L. Harinck, Kunal P. Pednekar, Jai Prakash, Olivier De Wever, Jeanne Leblond Chain, Stefaan C. De Smedt, Katrien Remaut, Koen Raemdonck · 2023 · International Journal of Pharmaceutics
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Development of siRNA Therapeutics for the Treatment of Liver Diseases
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Surface Plasmon Resonance Based Binding Characterization for Screening RNA-Loaded Lipid Nanoparticles (LNPs): Exploring Species Cross-Reactivity in LNP–Apolipoprotein E Interactions
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Endogenous Targeting of Lipid Nanoparticles to Kidney Tumors
Amogh Vaidya, Yun‐Chieh Sung, Vanina Toffessi Tcheuyap, Cheng Cheng Zhang, Ramesh Butti, Arijit Mal, Sean A. Dilliard, Jing Liu, Eunice Song, Erick Damian Guerrero et al. · 2025 · ACS Nano
Programmable lipid nanoparticles for RNA therapeutics: Design principles and clinical translation
Mahdi Navid Talemi, Marzieh Ramezani Farani, Naiyereh Alipour Eskandani, Danial Mirzaee, Iraj Alipourfard, Yun Suk Huh · 2026 · Materials Today Bio
Novel Lipid Nanoparticle (LNP) Delivery Systems Enabling the Advancement of RNA Therapeutics
Honglei Zhang, Shaowei Han, Xueyan Zhang, Jingxuan Ma, Lijie Jin, Yanfeng Wang, Yuqing Ma, Teng Ma, Fei Yu, Gengshen Song · 2026 · Advanced Healthcare Materials
A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery
Muye Zhou, Y Xu, Gen Li, Jingan Chen, Margarita Savguira, Breanna Y. Seto, Fanglin Gong, Tyler Thomson, Juan Chen, Rick Xing Ze Lu et al. · 2026 · Nature Biotechnology
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Impact of protein corona and PEGylation on the accumulation and efficacy of lysosome-disrupting lipid nanoparticles in KRAS-mutated cancer
Hangsheng Yang, Jiafeng Wang, Xinyi Zhou, Dongliang Fu, Chenqin Le, Jingsun Wei, Yucheng Qian, Yimin Fang, Tian Jin, Xiangxing Kong et al. · 2024 · Nano Today
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The absorption, distribution, metabolism and elimination characteristics of small interfering RNA therapeutics and the opportunity to predict disposition in pregnant women
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Targeted Lipid Nanoparticle Delivery of FAP-CAR mRNA Enables Potent In Vivo T-cell Engineering against Pancreatic Tumors
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