The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Genome sequence, comparative analysis and haplotype structure of the domestic dog
Open accessAbstract
Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris), together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The dog is of particular interest because it provides important evolutionary information and because existing breeds show great phenotypic diversity for morphological, physiological and behavioural traits. We use sequence comparison with the primate and rodent lineages to shed light on the structure and evolution of genomes and genes. Notably, the majority of the most highly conserved non-coding sequences in mammalian genomes are clustered near a small subset of genes with important roles in development. Analysis of SNPs reveals long-range haplotypes across the entire dog genome, and defines the nature of genetic diversity within and across breeds. The current SNP map now makes it possible for genome-wide association studies to identify genes responsible for diseases and traits, with important consequences for human and companion animal health.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The isolation of strains and breeds in these species results in much longer block lengths than are found in humans.”
From Linkage disequilibrium--understanding the evolutionary past and mapping the medical future. (2008) · cites this paper as [24]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Dogs were domesticated from grey wolves at least 15 000–50 000 years ago, through both natural and artificial selection [16,17].”
From Are dark-eyed dogs favoured by humans? Domestication as a potential driver of iris colour difference between dogs and wolves (2023) · cites this paper as [16]
Experimental — accuracy not yet measuredIn the citing paper
“The median value of K S is 1.02.”
From Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences (2007) · cites this paper as [10]
In the citing paper
“The most surprising discovery to emerge from comparative analyses of eutherian genomes is the finding that the majority of evolutionarily conserved sequence does not represent protein-coding genes, but rather are conserved non-coding elements (CNEs) 7,10 .”
From Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences (2007) · cites this paper as [10]
In the citing paper
“Strikingly, the proportion of eutherian-specific CNEs recognizable as transposable-element-derived (16%) is very similar to the proportion of the total aligned sequence between the human, mouse and dog genomes recognizable as ancestral transposable elements (,17% of ,812 Mb; the vast majority of which is inactive) 10 .”
From Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences (2007) · cites this paper as [10]
In the citing paper
“The Felis catus genome is predicted to contain 19,493 protein-coding genes and 1,855 noncoding RNAs, similar to dog (14).”
From Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication (2014) · cites this paper as [14]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625
Self-citationInitial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
Self-citationHaploview: analysis and visualization of LD and haplotype maps
Barrett, J. C., Fry, B., Maller, J., & Daly, M. J. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth457 · Cited by 14,551
Self-citationThe sequence of the human genome
Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
Self-citationLewis, B. P., Burge, C. B., & Bartel, D. P. (2005) · Cell · doi:10.1016/j.cell.2004.12.035 · Cited by 11,855
Mootha, V. K., Lindgren, C. M., Eriksson, K.-F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., et al. (2003) · Nature Genetics · doi:10.1038/ng1180 · Cited by 10,197
Self-citationInitial sequencing and comparative analysis of the mouse genome
Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187
Error bounds for convolutional codes and an asymptotically optimum decoding algorithm
Viterbi, A. J. (1967) · IEEE Transactions on Information Theory · doi:10.1109/tit.1967.1054010 · Cited by 6,954
The International HapMap Project
†The International HapMap Consortium, Genotyping centres: Baylor College of Medicine and ParAllele BioScience, Gibbs, R. A., Belmont, J. W., Hardenbol, P., Willis, T. D., Yu, F., Chinese HapMap Consortium, Yang, H., Ch'ang, L.-Y., et al. (2003) · Nature · doi:10.1038/nature02168 · Cited by 6,057
Self-citationThe Structure of Haplotype Blocks in the Human Genome
Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science · doi:10.1126/science.1069424 · Cited by 5,863
Self-citation
Flagged first, then by citations
Research works printed but not linked: 3
- Wilcox, B. & Walkowicz, C. The Atlas of Dog Breeds of the World (T.H.F. Publications, Neptune City, New York, 1995)
- Hudson, R. R. in Oxford Surveys in Evolutionary Biology Vol. 7 (eds Futuyma, D. & Antonovics, J.) 1–44 (Oxford Univ. Press, Oxford, 1990)
- Kajiwara, N. & Japanese Kennel Club in Akita (eds Kariyabu, T. & Kaluzniacki, S.) 1–103 (Japan Kennel Club, Tokyo, 1998)
Cited by
Sorted by citations
Items 701–800 of 1,006
Ancestral T-Box Mutation Is Present in Many, but Not All, Short-Tailed Dog Breeds
Hytönen, M. K., Grall, A., Hédan, B., Dréano, S., Seguin, S. J., Delattre, D., Thomas, A., Galibert, F., Paulin, L., Lohi, H., et al. (2008) · Journal of Heredity · doi:10.1093/jhered/esn085 · Cited by 47
Self-citationDiehl, W. E., Patel, N., Halm, K., & Johnson, W. E. (2016) · eLife · doi:10.7554/elife.12704 · Cited by 47
Goldstein, O., Mezey, J. G., Boyko, A. R., Gao, C., Wang, W., Bustamante, C. D., Anguish, L. J., Jordan, J. A., Pearce-Kelling, S. E., Aguirre, G. K., et al. (2010) · PubMed Central · Cited by 47
General pattern of meiotic recombination in male dogs estimated by MLH1 and RAD51 immunolocalization
Basheva, E. A., Bidau, C. J., & Бородин, П. М. (2008) · Chromosome Research · doi:10.1007/s10577-008-1221-y · Cited by 47
Misceo, D., Capozzi, O., Roberto, R., Dell’Oglio, M. P., Rocchi, M., Stanyon, R., & Archidiacono, N. (2008) · Genome Research · doi:10.1101/gr.078295.108 · Cited by 46
Finarelli, J. A., & Goswami, A. (2013) · Evolution · doi:10.1111/evo.12222 · Cited by 45
Teaching the Dog and Learning from the Dog: Interactivity in Herding Dog Training and Use
Savalois, N., Lescureux, N., & Brunois, F. (2013) · Anthrozoös · doi:10.2752/175303713x13534238631515 · Cited by 46
A revision of the fossil Canidae (Mammalia) of north‐western Africa
Geraads, D. (2011) · Palaeontology · doi:10.1111/j.1475-4983.2011.01039.x · Cited by 46
Establishing the foundation for an applied molecular taxonomy of otters in Southeast Asia
Koepfli, K., Kanchanasaka, B., Sasaki, H., Jacques, H., Louie, K. D., Hoai, T., Dang, N. X., Geffen, E., Gutleb, A. C., Han, S., et al. (2008) · Conservation Genetics · doi:10.1007/s10592-007-9498-5 · Cited by 46
Self-citationPilot, M., Moura, A. E., Okhlopkov, I. M., Викторович, М. Н., Manaseryan, N. H., Hayrapetyan, V., Kopaliani, N., Tsingarska, E., Alagaili, A. N., Mohammed, O. B., et al. (2021) · Evolutionary Applications · doi:10.1111/eva.13257 · Cited by 55
Self-citationEvolutionary conservation in noncoding genomic regions
Leypold, N. A., & Speicher, M. R. (2021) · Trends in Genetics · doi:10.1016/j.tig.2021.06.007 · Cited by 51
Vail, D. M., Thamm, D. H., & Liptak, J. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-59496-7.00033-5 · Cited by 45
Deregulated FOX genes in H odgkin lymphoma
Nagel, S., Meyer, C., Kaufmann, M., Drexler, H. G., & MacLeod, R. A. F. (2014) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22204 · Cited by 46
Wilbe, M., Sundberg, K., Hansen, I. R., Strandberg, E., Nachreiner, R. F., Hedhammar, Å. A., Kennedy, L. J., Andersson, G., & Björnerfeldt, S. (2010) · Tissue Antigens · doi:10.1111/j.1399-0039.2010.01449.x · Cited by 45
Neuronal cell differentiation of mesenchymal stem cells originating from canine amniotic fluid
Kim, E. Y., Lee, K.-B., Yu, J., Lee, J. H., Kim, K. J., Han, K.-W., Park, K.-S., Lee, D., & Kim, M. (2013) · Human Cell · doi:10.1007/s13577-013-0080-9 · Cited by 45
Murakami, S., Horimoto, T., Yamada, S., Kakugawa, S., Goto, H., & Kawaoka, Y. (2007) · Journal of Virology · doi:10.1128/jvi.01876-07 · Cited by 45
Indel seeds for homology search
Mak, D. Y. F., Gelfand, Y., & Benson, G. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl263 · Cited by 45
Serum Biochemical Phenotypes in the Domestic Dog
Chang, Y., Hadox, E., Szladovits, B., & Garden, O. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149650 · Cited by 45
Animal models of smoke inhalation injury and related acute and chronic lung diseases
Reczyńska-Kolman, K., Tharkar, P., Kim, S. Y., Wang, Y., Pamuła, E., Chan, H., & Chrzanowski, W. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.10.005 · Cited by 45
Structural variation during dog domestication: insights from gray wolf and dhole genomes
Wang, G., Shao, X.-J., Bai, B., Wang, J., Wang, X., Cao, X., Yan-hu, L., Wang, X., Yin, T.-T., Zhang, S., et al. (2018) · National Science Review · doi:10.1093/nsr/nwy076 · Cited by 48
Chibuk, J., Flory, A., Kruglyak, K. M., Leibman, N. F., Nahama, A., Dharajiya, N. G., van den Boom, D., Jensen, T. J., Friedman, J. S., Shen, M. R., et al. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.664718 · Cited by 45
Shan, S., Xu, F., & Brenig, B. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.693290 · Cited by 49
Alterations of keratins, involucrin and filaggrin gene expression in canine atopic dermatitis
Theerawatanasirikul, S., Sailasuta, A., Thanawongnuwech, R., & Suriyaphol, G. (2012) · Research in Veterinary Science · doi:10.1016/j.rvsc.2012.06.005 · Cited by 45
Oyama, M. A., Reiken, S. R., Lehnart, S. E., Chittur, S. V., Meurs, K. M., Stern, J. A., & Marks, A. R. (2008) · Journal of Veterinary Cardiology · doi:10.1016/j.jvc.2008.04.003 · Cited by 45
Dispensability of mammalian DNAPreprint
McLean, C. Y., & Bejerano, G. (2008) · Genome Research · doi:10.1101/gr.080184.108 · Cited by 46
Embryo biotechnology in the dog: a review
Chastant‐Maillard, S., Chebrout, M., Thoumire, S., Saint‐Dizier, M., Chodkiewicz, M., & Reynaud, K. (2010) · Reproduction Fertility and Development · doi:10.1071/rd09270 · Cited by 44
Inbreeding and genetic diversity in dogs: Results from DNA analysis
Wade, C. M. (2011) · The Veterinary Journal · doi:10.1016/j.tvjl.2011.06.017 · Cited by 44
Self-citationPeitsaro, N., Polianskyte-Prause, Z., Tuimala, J., Pörn-Ares, I., Liobikas, J., Speer, O., Lindholm, D., Thompson, J. S., & Eriksson, O. (2008) · BMC Evolutionary Biology · doi:10.1186/1471-2148-8-26 · Cited by 43
The Evolution and Diversity of DNA Transposons in the Genome of the Lizard Anolis carolinensis
Novick, P. A., Smith, J. D., Floumanhaft, M., Ray, D. A., & Boissinot, S. (2010) · Genome Biology and Evolution · doi:10.1093/gbe/evq080 · Cited by 44
So many doggone traits: mapping genetics of multiple phenotypes in the domestic dog
Rimbault, M., & Ostrander, E. A. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds323 · Cited by 47
Self-citationDraft genome of the gayal, Bos frontalis
Wang, M., Zeng, Y., Wang, X. R., Nie, W., Wang, J., Su, W., Otecko, N. O., Xiong, Z., Wang, S., Qu, K., et al. (2017) · GigaScience · doi:10.1093/gigascience/gix094 · Cited by 45
Phylogenetic reconstruction based on synteny block and gene adjacencies
Drillon, G., Champeimont, R., Oteri, F., Fischer, G., & Carbone, A. (2020) · Molecular Biology and Evolution · doi:10.1093/molbev/msaa114 · Cited by 46
Feuerborn, T. R., Carmagnini, A., Losey, R. J., Nomokonova, T., Askeyev, A., Askeyev, I., Askeyev, O., Евстафьевна, А. Е., Appelt, M., Bachura, O. P., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2100338118 · Cited by 44
A SELECTION MODEL OF MOLECULAR EVOLUTION INCORPORATING THE EFFECTIVE POPULATION SIZE
Ellegren, H. (2009) · Evolution · doi:10.1111/j.1558-5646.2008.00560.x · Cited by 43
Genetic evaluation of Addison's disease in the Portuguese Water Dog.
Oberbauer, A. M., Bell, J., Belanger, J. M., & Famula, T. R. (2006) · BMC Veterinary Research · doi:10.1186/1746-6148-2-15 · Cited by 44
Canine Anatomic Phantom for Preclinical Dosimetry in Internal Emitter Therapy
Padilla, L., Lee, C., Milner, R. J., Shahlaee, A. H., & Bolch, W. E. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.046722 · Cited by 44
Anesthetic Properties of Carbon Dioxide in the Rat
Brosnan, R. J., Eger, E. I., Laster, M. J., & Sonner, J. M. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000265556.69089.78 · Cited by 44
Kyöstilä, K., Lappalainen, A. K., & Lohi, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075621 · Cited by 44
The importance of comparative oncology in translational medicine
Riccardo, F., Aurisicchio, L., Impellizeri, J. A., & Cavallo, F. (2014) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-014-1645-5 · Cited by 43
Zhuo, X., Rho, M., & Feschotte, C. (2013) · Journal of Virology · doi:10.1128/jvi.00892-13 · Cited by 43
The canid genome: behavioral geneticists' best friend?
Hall, N. J., & Wynne, C. D. L. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00851.x · Cited by 46
Vrieze, S. I., Iacono, W. G., & McGue, M. K. (2012) · Development and Psychopathology · doi:10.1017/s0954579412000648 · Cited by 46
Innes, J., & Clegg, P. (2010) · Lara D. Veeken · doi:10.1093/rheumatology/kep465 · Cited by 43
A selective sweep of >8 Mb on chromosome 26 in the Boxer genome
Quilez, J., Short, A. D., Martinez-Diaz, V. L., Kennedy, L. J., Ollier, W., Sánchez, A., Altet, L., & Francino, O. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-339 · Cited by 43
Feeding habits of extant and fossil canids as determined by their skull geometry
Meloro, C., Hudson, A., & Rook, L. (2014) · Journal of Zoology · doi:10.1111/jzo.12196 · Cited by 43
Molecular evolution of piggyBac superfamily: from selfishness to domestication
Bouallègue, M., Rouault, J.-D., Hua‐Van, A., Makni, M., & Capy, P. (2016) · Genome Biology and Evolution · doi:10.1093/gbe/evw292 · Cited by 43
BarkBase: Epigenomic Annotation of Canine Genomes
Megquier, K., Genereux, D. P., Hekman, J. P., Swofford, R., Turner-Maier, J., Johnson, J., Alonso, J., Li, X., Morrill, K. M., Anguish, L. J., et al. (2019) · Genes · doi:10.3390/genes10060433 · Cited by 42
Self-citationSulkama, S., Puurunen, J., Salonen, M. K., Mikkola, S., Hakanen, E., Araujo, C., & Lohi, H. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01626-x · Cited by 51
Estimating the Neutral Rate of Nucleotide Substitution Using Introns
Hoffman, M. M., & Birney, E. (2006) · Molecular Biology and Evolution · doi:10.1093/molbev/msl179 · Cited by 42
Freiche, V., Cordonnier, N., Paulin, M. V., Huet, H., Turba, M. E., Macintyre, E. A., Malamut, G., Cerf–Bensussan, N., Molina, T. J., Hermine, O., et al. (2021) · Laboratory Investigation · doi:10.1038/s41374-021-00581-x · Cited by 42
Rocha, J. L., Silva, P., Santos, N., Nakamura, M., Afonso, S., Qninba, A., Boratyński, Z., Sudmant, P. H., Brito, J. C., Nielsen, R., et al. (2023) · Nature Ecology & Evolution · doi:10.1038/s41559-023-02094-w · Cited by 46
Leite, J. V., Álvares, F., Velo‐Antón, G., Brito, J. C., & Godinho, R. (2015) · Organisms Diversity & Evolution · doi:10.1007/s13127-015-0232-8 · Cited by 40
Evidence of Coat Color Variation Sheds New Light on Ancient Canids
Ollivier, M., Tresset, A., Hitte, C., Petit, C., Hughes, S., Gillet, B., Duffraisse, M., Pionnier-Capitan, M., Lagoutte, L., Arbogast, R., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075110 · Cited by 42
Self-citationKummer, S., Flöttmann, M., Schwanhäußer, B., Sieben, C., Veit, M., Selbach, M., Klipp, E., & Herrmann, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094257 · Cited by 43
Computation and Analysis of Genomic Multi-Sequence Alignments
Blanchette, M. (2007) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.8.080706.092300 · Cited by 43
Proteomics of Canine Lymphoma Identifies Potential Cancer-Specific Protein Markers
McCaw, D. L., Chan, A. S., Stegner, A. L., Mooney, B., Bryan, J. N., Turnquist, S. E., Henry, C. J., Alexander, H., & Alexander, S. P. H. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-2699 · Cited by 42
Unexpected High Polymorphism at the FABP4 Gene Unveils a Complex History for Pig Populations
Ojeda, A., Rozas, J., Folch, J. M., & Miguel Pérez-enciso, A. (2006) · Genetics · doi:10.1534/genetics.106.063057 · Cited by 42
Gastric carcinoma in canines and humans, a review
Hugen, S., Thomas, R., German, A. J., Burgener, I. A., & Mandigers, P. J. J. (2016) · Veterinary and Comparative Oncology · doi:10.1111/vco.12249 · Cited by 42
Self-citationCross‐species analysis of the canine and human bladder cancer transcriptome and exome
Ramsey, S. A., Xu, T., Goodall, C. P., Rhodes, A. C. E., Kashyap, A., He, J., & Bracha, S. (2017) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22441 · Cited by 43
Borge, K. S., Nord, S., Loo, P. V., Lingjærde, O. C., Gunnes, G., Alnæs, G. I. G., Solvang, H. K., Lüders, T., Kristensen, V. N., Børresen‐Dale, A., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0126371 · Cited by 42
Principles and methods of in-silico prioritization of non-coding regulatory variants
Lee, P. H., Lee, C. R., Li, X., Wee, B., Dwivedi, T., & Daly, M. J. (2017) · Human Genetics · doi:10.1007/s00439-017-1861-0 · Cited by 46
Self-citationHarmoinen, J., von Thaden, A., Aspi, J. O., Kvist, L., Cocchiararo, B., Jarausch, A., Gazzola, A., Sin, T., Lohi, H., Hytönen, M. K., et al. (2021) · BMC Genomics · doi:10.1186/s12864-021-07761-5 · Cited by 42
Identification of Risk Loci for Necrotizing Meningoencephalitis in Pug Dogs
Barber, R. M., Schatzberg, S. J., Corneveaux, J. J., Allen, A. N., Porter, B. F., Pruzin, J. J., Platt, S. R., Kent, M., & Huentelman, M. J. (2011) · Journal of Heredity · doi:10.1093/jhered/esr048 · Cited by 42
Bauer, T. R., Hai, M., Tuschong, L. M., Burkholder, T. H., Gu, Y.-C., Sokolic, R. A., Ferguson, C., Dunbar, C. E., & Hickstein, D. D. (2006) · Blood · doi:10.1182/blood-2006-03-006908 · Cited by 42
Role of golden jackals (Canis aureus) as natural reservoirs of Dirofilaria spp. in Romania
Ionică, A. M., Matei, I. A., D’Amico, G., Daskalaki, A. A., Juránková, J., Ionescu, D. T., Mihalca, A. D., Modrý, D., & Gherman, C. M. (2016) · Parasites & Vectors · doi:10.1186/s13071-016-1524-3 · Cited by 41
Dhein, E. S., Heikkilä, U., Oevermann, A., Blatter, S., Meier, D., Hartnack, S., & Guscetti, F. (2024) · PLoS ONE · doi:10.1371/journal.pone.0302231 · Cited by 41
Safra, N., Bassuk, A. G., Ferguson, P. J., Aguilar, M., Coulson, R. L., Thomas, N. C., Hitchens, P. L., Dickinson, P. J., Vernau, K. M., Wolf, Z. T., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003646 · Cited by 41
Paoloni, M. C., Webb, C. P., Mazcko, C. N., Cherba, D., Hendricks, W. P. D., Lana, S. E., Ehrhart, E. J., Charles, B., Fehling, H. L., Kumar, L., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090028 · Cited by 41
Kathrani, A., House, A., Catchpole, B., Murphy, A., Werling, D., & Allenspach, K. (2011) · Tissue Antigens · doi:10.1111/j.1399-0039.2011.01707.x · Cited by 41
van den Berg, L., Vos‐Loohuis, M., Schilder, M. B. H., van Oost, B. A., Hazewinkel, H. A. W., Wade, C. M., Karlsson, E. K., Lindblad‐Toh, K., Liinamo, A.-E., & Leegwater, P. A. J. (2007) · Behavior Genetics · doi:10.1007/s10519-007-9179-7 · Cited by 41
Self-citationComparative oncology: Integrating human and veterinary medicine
Sultan, F., & Ganaie, B. A. (2018) · Open Veterinary Journal · doi:10.4314/ovj.v8i1.5 · Cited by 40
Shepherd, C., Wangchuk, P., & Loukas, A. C. (2018) · Parasites & Vectors · doi:10.1186/s13071-018-2621-2 · Cited by 42
A canine identity crisis: Genetic breed heritage testing of shelter dogs
Gunter, L. M., Barber, R. T., & Wynne, C. D. L. (2018) · PLoS ONE · doi:10.1371/journal.pone.0202633 · Cited by 48
Mooney, J. A., Marsden, C. D., Yohannes, A., Wayne, R. K., & Lohmueller, K. E. (2022) · Molecular Biology and Evolution · doi:10.1093/molbev/msac277 · Cited by 44
Self-citationLinked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds
Webster, M. T., Kamgari, N., Perloski, M., Hoeppner, M. P., Axelsson, E., Hedhammar, Å. A., Pielberg, G., & Lindblad‐Toh, K. (2015) · BMC Genomics · doi:10.1186/s12864-015-1702-2 · Cited by 41
Self-citationThe dog as an animal model for DISH?
Kranenburg, H. C., Westerveld, L. A., Verlaan, J., Öner, F. C., Dhert, W. J. A., Voorhout, G., Hazewinkel, H. A. W., & Meij, B. P. (2010) · European Spine Journal · doi:10.1007/s00586-010-1280-6 · Cited by 41
Liu, G. E., Matukumalli, L. K., Sonstegard, T. S., Shade, L. L., & Tassell, C. P. V. (2006) · BMC Genomics · doi:10.1186/1471-2164-7-140 · Cited by 41
Thomas, R. J., Wiley, C. A., Droste, E. L., Robertson, J. B., Inman, B. A., & Breen, M. (2023) · PLoS Genetics · doi:10.1371/journal.pgen.1010575 · Cited by 40
Self-citationSafra, N., Pedersen, N. C., Wolf, Z. T., Johnson, E. G., Liu, H. W., Hughes, A. M., Young, A. E., & Bannasch, D. L. (2011) · The Veterinary Journal · doi:10.1016/j.tvjl.2011.06.023 · Cited by 40
Ploper, D., Lee, H. X., & Robertis, E. M. D. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.01.029 · Cited by 40
Genetic comparisons yield insight into the evolution of enamel thickness during human evolution
Horvath, J. E., Ramachandran, G. L., Fedrigo, O. D., Nielsen, W., Babbitt, C. C., Clair, E. M. S., Pfefferle, L. W., Jernvall, J., Wray, G. A., & Wall, C. E. (2014) · Journal of Human Evolution · doi:10.1016/j.jhevol.2014.01.005 · Cited by 42
Aging Research 2011: Exploring the Pet Dog Paradigm
Waters, D. J. (2011) · ILAR Journal · doi:10.1093/ilar.52.1.97 · Cited by 40
Genetics of Adiposity in Large Animal Models for Human Obesity—Studies on Pigs and Dogs
Stachowiak, M., Szczerbal, I., & Switonski, M. (2016) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2016.01.001 · Cited by 39
Waugh, E. M., Gallagher, A., Haining, H., Johnston, P., Marchesi, F., Jarrett, R. F., & Morris, J. S. (2016) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2016.10.008 · Cited by 40
A comparative review of intelectins
Chen, L., Li, J., & Yang, G. (2020) · Scandinavian Journal of Immunology · doi:10.1111/sji.12882 · Cited by 41
Canine prostate cancer cell line (Probasco) produces osteoblastic metastases in vivo
Simmons, J. K., Dirksen, W. P., Hildreth, B. E., Dorr, C., Williams, C., Thomas, R. J., Breen, M., Toribio, R. E., & Rosol, T. J. (2014) · The Prostate · doi:10.1002/pros.22838 · Cited by 43
Self-citationDog and mouse: toward a balanced view of the mammalian olfactory system
Barrios, A. W., Sánchez‐Quinteiro, P., & Salazar, I. (2014) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00106 · Cited by 38
Atlas of ACE2 gene expression in mammals reveals novel insights in transmisson of SARS-Cov-2Preprint
Sun, K., Gu, L., Ma, L., & Duan, Y. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.30.015644 · Cited by 38
Cahill, J. A., Armstrong, J. C., Deran, A., Khoury, C. J., Paten, B., Haussler, D. H., & Jarvis, E. D. (2021) · Genome Research · doi:10.1101/gr.275989.121 · Cited by 43
Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes
Broeckx, B. J. G., Hitte, C., Coopman, F., Verhoeven, G. E. C., Keulenaer, S. D., Meester, E. D., Derrien, T., Alföldi, J., Lindblad‐Toh, K., Bosmans, T., et al. (2015) · Scientific Reports · doi:10.1038/srep12810 · Cited by 39
Self-citationAn approach to canine behavioural genetics employing guide dogs for the blind
Takeuchi, Y., Hashizume, C., Arata, S., Inoue‐Murayama, M., Maki, T., Hart, B. L., & Mori, Y. (2009) · Animal Genetics · doi:10.1111/j.1365-2052.2008.01823.x · Cited by 39
Boerkamp, K. M., Teske, E., Boon, L. R., Grinwis, G. C. M., den Bossche, L. V., & Rutteman, G. R. (2014) · BMC Veterinary Research · doi:10.1186/1746-6148-10-34 · Cited by 45
Genetics of behavior in the silver fox
Kukekova, A. V., Temnykh, S. V., Johnson, J. L., Trut, L. N., & Acland, G. M. (2011) · Mammalian Genome · doi:10.1007/s00335-011-9373-z · Cited by 40
Beckmann, M., Enot, D. P., Overy, D. P., Scott, I. M., Jones, P. G., Allaway, D., & Draper, J. (2009) · British Journal Of Nutrition · doi:10.1017/s000711450999300x · Cited by 39
Chavez, D. E., Gronau, I., Hains, T., Kliver, S. F., Koepfli, K., & Wayne, R. K. (2019) · Scientific Reports · doi:10.1038/s41598-019-44772-5 · Cited by 40
Self-citationImproving immunological insights into the ferret model of human viral infectious disease
Wong, J., Layton, D., Wheatley, A. K., & Kent, S. J. (2019) · Influenza and Other Respiratory Viruses · doi:10.1111/irv.12687 · Cited by 39
Stable Genome Incorporation of Sperm-derived DNA Fragments in Gynogenetic Clone of Gibel Carp
Chen, F., Li, X., Zhou, L., Yu, P., Wang, Z., Li, Z., Zhang, X., Wang, Y., & Gui, J. (2020) · Marine Biotechnology · doi:10.1007/s10126-019-09930-w · Cited by 39
Mutations of BRCA2 in canine mammary tumors and their targeting potential in clinical therapy
Thumser‐Henner, P., Nytko, K. J., & Bley, C. R. (2020) · BMC Veterinary Research · doi:10.1186/s12917-020-2247-4 · Cited by 46
Whole‐genome analyses provide no evidence for dog introgression in Fennoscandian wolf populations
Smeds, L., Aspi, J. O., Berglund, J., Kojola, I., Тирронен, К. Ф., & Ellegren, H. (2020) · Evolutionary Applications · doi:10.1111/eva.13151 · Cited by 39
Wu, K., Rodrigues, L., Post, G. S., Harvey, G., White, M. E., Miller, A., Lambert, L., Lewis, B., Lopes, C., & Zou, J. (2023) · npj Precision Oncology · doi:10.1038/s41698-023-00346-3 · Cited by 46
Metadata
- Authors
- members, B. S. P., Lindblad-Toh, K., Wade, C. M., Mikkelsen, T. S., Karlsson, E. K., Jaffe, D. B., Kamal, M., Clamp, M., Chang, J. L., Kulbokas, E. J., Zody, M. C., Mauceli, E., Xie, X., Breen, M., Wayne, R. K., Ostrander, E. A., Ponting, C. P., Galibert, F., Smith, D. R., deJong, P. J., Kirkness, E., Alvarez, P., Biagi, T., Brockman, W., Butler, J., Chin, C.-W., Cook, A., Cuff, J., Daly, M. J., DeCaprio, D., Gnerre, S., Grabherr, M., Kellis, M., Kleber, M., Bardeleben, C., Goodstadt, L., Heger, A., Hitte, C., Kim, L., Koepfli, K.-P., Parker, H. G., Pollinger, J. P., Searle, S. M. J., Sutter, N. B., Thomas, R., Webber, C., & Lander, E. S.
- Affiliations
- Broad Institute (US)
- North Carolina State University (US)
- National Institutes of Health (US)
- Centre National de la Recherche Scientifique (FR)
- University of California, Los Angeles (US)
- University of Oxford (GB)
- Corresponding author
- Lander, Eric S.
- ORCID
- Wade, Claire M
- Mikkelsen, Tarjei S.
- Karlsson, Elinor K.
- Jaffe, David B.
- Zody, Michael C.
- Xie, Xiaohui
- Breen, Matthew
- Wayne, Robert K.
- Ostrander, Elaine A.
- Ponting, Chris P.
- Galibert, Francis
- Alvarez, Pablo
- Cuff, James
- Daly, Mark J.
- DeCaprio, David
- Grabherr, Manfred
- Kellis, Manolis
- Heger, Andreas
- Hitte, Christophe
- Kim, Lisa
- Koepfli, Klaus-Peter
- Parker, Heidi G.
- Pollinger, John P.
- Sutter, Nathan B.
- Thomas, Rachael
- Webber, Caleb
- Lander, Eric S.
- Venue
- Nature
- Published
- 2005-12
- Volume
- 438
- Issue
- 7069
- Pages
- 803-819
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2114611642
- Semantic Scholar
- b01f00857b9abec4f245c665c5042824f5430711
- Cited by
- 2,568
- References
- 115
- Citations by year
- 2026: 40 · 2025: 66 · 2024: 94 · 2023: 106 · 2022: 95 · 2021: 122 · 2020: 141 · 2019: 122 · 2018: 114 · 2017: 88 · 2016: 116 · 2015: 138 · 2014: 140 · 2013: 131 · 2012: 144
- FWCI
- 84.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Funders
- National Institutes of Health
- National Human Genome Research Institute
- Topics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Human-Animal Interaction Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and phenotypic traits in livestock
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Keywords
- dogs, single nucleotide polymorphisms, breed genetic diversity, haplotype structure, genome evolution, comparative genomics, conserved non-coding elements, genome-wide association study, dog breeds
- MeSH terms
- Animals, Dog Diseases, Dogs, Female, Haplotypes, Humans, Hybridization, Genetic, Male, Mutagenesis, Genome, Conserved Sequence, Evolution, Molecular, Short Interspersed Nucleotide Elements, Polymorphism, Single Nucleotide, Genomics, Synteny, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
