PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
Zhang, Jiwang, Grindley, Justin C., Yin, Tong, Jayasinghe, Sachintha, He, Xi C., Ross, Jason T., Haug, Jeffrey S., Rupp, Dawn, Porter-Westpfahl, Kimberly S., Wiedemann, Leanne M., Wu, Hong, Li, Linheng·2006·Nature
Cited by (814)
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- ATP Binding Cassette Transporters in Cancer Stem-Like CellsPaola Perego · 2014 · Resistance to targeted anti-cancer therapeutics
- The Role of MicroRNAs in Hematopoietic Stem Cells and Leukemia DevelopmentSafak Yalcin, Stephen S. Chung, Christopher Y. Park · 2014 · Springer eBooks
- Stem Cell Characters in Primary and Metastatic Tumour EstablishmentMaria Tsekrekou, Dimitris Mavroudis, Dimitris Kafetzopoulos, Despoina Vassou · 2011 · Springer eBooks
- Developing a Systems-Based Understanding of Hematopoietic Stem Cell Cycle ControlKa Tat Siu, Alex C. Minella · 2014 · Advances in experimental medicine and biology
- Genetic and Signaling Pathway Regulations of Tumor-Initiating Cells of the ProstateDavid J. Mulholland, Hong Wu · 2013 · Springer eBooks
- Molecular Mechanisms Underlying Bone Marrow Homing of Hematopoietic Stem CellsAysegul Ocal Sahin, Miranda Buitenhuis · 2012 · InTech eBooks
- p53 as a Therapeutic Target in T-ALLIrene Riz, Wenjing Yang, Weiqun Peng, G. Robert · 2011 · InTech eBooks
- Stem Cell BiologyElizabeth Olson Hexner, Stephen G. Emerson · 2008 · Humana Press eBooks
- Cancer Stem CellQiang Liu, Feng-Yan Yu, Wei Tang, Shi-Cheng Su, Er-Wei Song · 2012 · Elsevier eBooks
- A Forecast of Targeting Leukemia Stem Cells by NanomedicineXiangwei Huang, Xunlei Kang, Meng Liang Zhao · 2017 · Journal of Stem Cell Research & Therapy
- Myelodysplastic Syndromes and Myeloproliferative Neoplasms in ChildrenFranklin O. Smith, Christopher C. Dvorak, Benjamin S. Braun · 2017 · Elsevier eBooks
- Cancer Stem Cells and Head and Neck Squamous Cell CarcinomasShi‐Long Lu · 2011 · Springer eBooks
- Protein Kinase CK2 in Normal and Malignant HematopoiesisFrancesco Piazza · 2013 · Wiley eBooks
- Identification of cooperating genetic events in acute leukemiaTing Liu · 2009 · edoc (University of Basel)
- Stem Cell Dormancy: Maintaining a Reserved PopulationJohn M. Perry, Xi C. He, Ryohichi Sugimura, Linheng Li · 2013 · Wiley-VCH eBooks
- Mouse Models of Human Cancer: Role in Preclinical Testing and Personalized MedicineAlice H. Berger, Pier Paolo Pandolfi · 2011 · Springer eBooks
- Cancer as a microevolutionary processNatalia L. Komarova, Dominik Wodarz · 2007 · Oxford University Press eBooks
- Whole-genome analysis of pathogen evolutionJulian Parkhill · 2007 · Oxford University Press eBooks
- Stem Cells Signaling Pathways in the HeartJosé Marín-García · 2011 · Springer eBooks
- The Notch1-c-Myc Pathway Mediates Leukemia-Initiating Cell Activity in Mouse T-ALL Models: A DissertationJessica Tesell · 2013 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
- Metabolic and Energetic Regulation of Stem CellsA. Esteves, Toren Finkel · 2015 · Elsevier eBooks
- DNMT3b's Role in Hematopoietic Stem CellsMatthew J. Boyer · 2010 · D-Scholarship@Pitt (University of Pittsburgh)
- Fates of blood : Studies on stem cell differentiation potential and B lymphocyte generation in chimeric cattleMikael Niku · 2007 · Työväentutkimus Vuosikirja
- The PI3K/PKB Signaling Module in Normal and Malignant HematopoiesisRoel Polak, Miranda Buitenhuis · 2011 · InTech eBooks
- The effects of Phosphatase and Tensin Homolog (PTEN) overexpression on longevity of cultured Human Umbilical Vein Endothelial Cells (HUVEC)Izak Tait · 2014 · Tuwhera (Auckland University of Technology)
- Mechanism of Functional Alterations in Hematopoietic Stem Cell AgingYohei Morita · 2014 · Else Kröner-Fresenius Symposia
- Novel Therapeutic Targets for Ph+ Chromosome Leukemia and Its Leukemia Stem Cells: A DissertationCong Peng · 2010 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
- Inositol Phospholipid and Tyrosine Phosphorylation Signaling in the Biology of Hematopoietic Stem CellsAmy L. Hazen · 2009 · Digital Commons - University of South Florida (University of South Florida)
- Ativação e bloqueio, da via de sinalização do PI3K, em células cultivadas de carcinoma epidermóide: correlação com a expressão das proteínas AKT, B-catenina, ciclina D1 e PTENKatiuchia Uzzun Sales · 2006 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- The role of the transcription factor 3 gene product E47 in multipotent hematopoietic stem cells and progenitorsQi Yang · 2010 · D-Scholarship@Pitt (University of Pittsburgh)
- Regulation of HSC Self-Renewal and Differentiation by Pumilio ProteinsJennifer Zayas · 2008
- Genetic Modeling of Human Blood Cancers in MiceYiguo Hu, Shaoguang Li · 2008 · Springer eBooks
- [Stem cells and the origin of colon cancer].Fabio Salamanca-Gómez · 2007 · PubMed
- The Riboproteome Orchestrates Self‐Renewal and Cell Fate in LeukemiaElianna Mohamed Amin, Michael G. Kharas · 2014 · Wiley eBooks
- Hematopoietic Stem Cell Aging and Fate DecisionAnett Illing, Zhenyu Ju · 2010 · Else Kröner-Fresenius Symposia
- The Role of Hox Transcription Factors in the Regulation of HematopoiesisMattias Magnusson · 2007 · Lund University Publications (Lund University)
- Immunorecognition of leukemic stem cells by NK cells : the role of HDAC inhibitors in NKG2D ligand-mediated anti-tumor responses in acute myeloid leukemiaUlrich Langenkamp · 2008 · edoc (University of Basel)
- Cancer stem cell patentsBrynn T. Kvinlaug, Stanley E. Lazic · 2008 · Expert Opinion on Therapeutic Patents
- Glioma: challenges and new insights in the development of effective therapies.Sandra Pastorino, Joe William Ramos · 2008 · PubMed
- Deciphering a Kit-Shp2-Kit Axis in Regulation of Adult Hematopoietic Stem and Progenitor CellsHe Zhu · 2011 · eScholarship (California Digital Library)
- ORIGINAL ARTICLE / RESEARCHRajesh R. Sharma, O C Bharti, Dharamendra Kumar · 2007
- The Stem Cell Niche and Its Role in Self-Renewal, Aging, and MalignancyS.J. Peter Breslin, Andrew G. Volk, Jiwang Zhang · 2013 · Wiley-VCH eBooks
- 뀀Ƞ THE FLT3 TYROSINE KINASE IN LEUKEMIAAmanda Nordigården · 2013
- The role of the tumor suppressor PTEN in bone homeostasisMichel G. Arsenault · 2008 · eScholarship@McGill (McGill)
- Leukemia Stem CellsMarkus Müschen · 2009 · Springer eBooks
- Estudo do IL-7R na leucemia linfóide aguda pediátrica de linhagem TPriscila Pini Zenatti · 2012
- Metabolic Peculiarities of the Stem Cell EntityZoran Ivanović, Marija Vlaski‐Lafarge · 2015 · Elsevier eBooks
- Eosinophil Signal Transduction2012 · Elsevier eBooks
- Mutações de PTEN nas leucemias linfóides agudas TPatricia Yoshioka Jotta · 2012
- Embryonic Diapause as a Model for Pluripotent Stem Cell QuiescenceLilyana Margaretha · 2012 · ResearchWorks at the University of Washington (University of Washington)
- Inhibition of the phosphatidylinositol-3-kinase pathway is selectively cytotoxic to primitive and mature acute myeloid leukemia progenitor cells while sparing their normal counterpartsAndrew Muranyi · 2009 · cIRcle (University of British Columbia)
- Stem Cells: What Are They and Why Do We Need Them?Leah Bellehsen, Arnon Nagler, Francesca Levi‐Schaffer · 2009 · Elsevier eBooks
- 16. Oxidative stress, leukemia growth and possible therapiesAdeeb Shehzad, Hira Zahid, M. Shahid, Y.S. Lee · 2016 · Wageningen Academic Publishers eBooks
- Literatur und NachweiseDeutsche Forschungsgemeinschaft (DFG), Senatskommission für Grundsatzfragen der Genforschung · 2007 · Wiley eBooks
- Medically relevant variation in the human genomeDiddahally R. Govindaraju, Lynn B. Jorde · 2007 · Oxford University Press eBooks
- The Role of PI3K/AKT/mTOR Inhibitors in the Treatment of Hematological MalignanciesZheng Shen, Kevin R. Kelly · 2015 · Springer eBooks
- Expansion of Human Hematopoietic Stem CellsColleen S. Delaney · 2015 · Wiley eBooks
- Downregulation of Prdm16 Is Critical for HOXB4-mediated Benign HSC Expansion In VivoHui Yu · 2014
- Pten Function in Postnatal Brain Development and TumorigenesisGuo Gord Zhu · 2011
- Neutrophil SHIP1 and PTEN Deficiency and Response to Sterile InjuryKeir Pittman · 2016 · Libraries and Cultural Resources (University of Calgary)
- Distinguishing featuresPatrick Goymer · 2006 · Nature reviews. Cancer
- Multi-target analysis of neoplasms for the evaluation of tumor progression: stochastic approach of biologic processesFatima Al‐Hashimi, Salvador J. Díaz‐Cano · 2018 · AIMS molecular science
- Foxo Transcription Factors Control Spermatogonial Stem Cell Self-Renewal and the Initiation of SpermatogenesisMeredith J. Goertz · 2013
- A participação da autofagia na regulação da célula-tronco hemopoética em camundongos knockouts para Atg7 e transglutaminase 2Jackeline Soares de Oliveira Beltran · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Elucidation of functions of PTEN in pancreatic carcinogenesis and its therapeutic application방승민 · 2010 · YUHSpace (Yonsei University Medical Library)
- STAT3β is a tumor suppressor in acute myeloid leukemiaPetra Aigner · 2019 · Intrinsic Activity
- Combinatorial effect of miR-486-5p & miR-22-3p mimics thrombopoietin’s impact on hematopoietic stem & progenitor cellsChen‐Yuan Kao, Jinlin Jiang, Eleftherios Terry Papoutsakis · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Investigating competitive interactions between normal and transformed neural stem cellsKaterina Lawlor · 2019
- Genotype-phenotype correlations in mouse musculoskeletal development and diseaseAlice Fiona Ford-Hutchinson · 2006 · Libraries and Cultural Resources (University of Calgary)
- THE INFLUENCE OF INTRAVENOUS HYDRATION ON HOSPITAL LENGTH OF STAY IN INFANTS WITH HYPERBILIRUBINEMIAMarjorie K Leimomi Mala Mau, Douglas Yee, Hideko Yamauchi, Elisabeth N Biuk-Aghai, Hao Chih Ho, Alyssa D. Chapital, Danny M. Takanishi · 2007
- PKC en un microambiente leucémico con células stem mesenquimales: Su participación en el soporte, la supervivencia y los mecanismos que median la protección ante agentes quimioterapéuticos en células de pacientes con Leucemia Linfoide Aguda de precursores BRuiz Aparicio, Paola Fernanda · 2020
- Influence of Corporate Social Responsibility on Organizational Citizenship Behavior through Double Mediation AnalysisFarah Khan · 2019 · Jinnah Business Review
- Live and Let Die : Critical regulation of survival in normal and malignant hematopoietic stem and progenitor cellsPernilla Eliasson · 2009 · DiVA (Linkoping University)
- PTEN in Hematopoietic and Intestinal Stem Cells and CancerJason T. Ross, David H. Scoville, Xi He, Linheng Li · 2009 · Humana Press eBooks
- Consequences of Shb Deficiency on Hematopoietic Cell FunctionKarin U. Gustafsson · 2013 · Uppsala University Publications (Uppsala University)
- Full PDF of Hematology Reviews 2009, volume 1, issue 1.The Lancet Oncology Editors · 2011 · Hematology Reports
- Transgenic Research2013 · Transgenic Research
- Bcl-2 associated transcription factor 1 promotes proliferation but inhibits self-renewal of embryonic spinal cord neural stem/progenitor cells through enhancing the mammalian target of rapamycin complex 1 signalingXu He, Pian Li, Zhengwen Kang, He Tian, Ping Miao, Qiusheng Zhang, Wenping Lin · 2022 · Research Square
- Preface to the Second Edition2007 · Oxford University Press eBooks
- Copyright Page2007 · Oxford University Press eBooks
- Contributors2007 · Oxford University Press eBooks
- PTEN in ImmunityAntonella Papa, Pier Paolo Pandolfi · 2022 · Current topics in microbiology and immunology
- Data from Expression of the Transcriptional Repressor Gfi-1 Is Regulated by C/EBPα and Is Involved in Its Proliferation and Colony Formation–Inhibitory Effects in p210BCR/ABL-Expressing CellsMaria Rosa Lidonnici, Alessandra Audia, Angela Rachele Soliera, Marco di Prisco, Giovanna Ferrari‐Amorotti, Todd J. Waldron, Nick J. Donato, Ying Zhang, Robert V. P. Martinez, Tessa L. Holyoake et al. · 2023
- Data from Morin Inhibits Proliferation and Induces Apoptosis by Modulating the miR-188-5p/PTEN/AKT Regulatory Pathway in CML CellsZi-Yuan Nie, Lin Yang, Xiaojun Liu, Zhan Yang, Gaoshan Yang, Jing Zhou, Qin Yan, Jing Xia Yu, Lingling Jiang, Jin‐Kun Wen et al. · 2023
- Genetic and Epigenetic Profiles in T-ALLBüşra Erarslan Uysal, Andreas E. Kulozik · 2024 · Pediatric oncology
- Characterizing the dual role of Headcase in hemocyte progenitor maintenance in Drosophila melanogasterBayan Kharrat · 2024
- Genetic and cell biological aspects of PTEN in prostate cancerPetra W. van Duijn · 2008 · RePub (Erasmus University Rotterdam)
- Role of the post-transcriptional regulators Pumilio1 and Pumilio2 in murine hematopoietic stem cellsFabio Michelet · 2013 · theses.fr (ABES)
- Rôle des facteurs de transcription HIF (Hypoxia Inducible Factor) dans le maintien à long terme des cellules souches hématopoïétiques humaines chez la souris immunodéficienteKevin Rouault-Pierre · 2010 · theses.fr (ABES)
- Identification et caractérisation de la fonction d’un réseau de gènes soumis à empreinteBrendan Evano · 2012 · theses.fr (ABES)