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Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
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Sakaguchi, S. (2005) · Nature Immunology · doi:10.1038/ni1178 · Cited by 2,669
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Digital signaling and hysteresis characterize Ras activation in lymphoid cells.
Das, J., Ho, M., Zikherman, J., Govern, C., Yang, M., Weiss, A., Chakraborty, A. K., & Roose, J. P. (2009) · Cell · doi:10.1016/j.cell.2008.11.051 · Cited by 398
“The threshold potency above which strongly binding ligands negatively select thymocytes in the thymus is very sharp while the positive selection threshold is graded (Daniels et al., 2006).”
Balmer, M. L., Ma, E. H., Bantug, G. R., Grählert, J., Pfister, S., Glatter, T., Jauch, A., Dimeloe, S., Slack, E., Dehio, P., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.03.016 · Cited by 361
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Liu, H., Luo, H., Xue, Q., Qin, S., Qiu, S., Liu, S., Lin, J., Li, J. P., & Chen, P. R. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c00159 · Cited by 88
Kashyap, A. S., Fernandez-Rodriguez, L., Zhao, Y., Monaco, G., Trefny, M. P., Yoshida, N., Martin, K., Sharma, A., Olieric, N., Shah, P., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.08.057 · Cited by 76
Zhou, R. W., Mkhikian, H., Grigorian, A., Hong, A., Chen, D., Arakelyan, A., & Demetriou, M. (2014) · Nature Immunology · doi:10.1038/ni.3007 · Cited by 59
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Metadata
- Authors
- Daniels, M. A., Teixeiro, E., Gill, J., Hausmann, B., Roubaty, D., Holmberg, K., Werlen, G., Holländer, G. A., Gascoigne, N. R. J., & Palmer, E.
- Venue
- Nature
- Published
- 2006-11-01
- Volume
- 444
- Issue
- 7120
- Pages
- 724-729
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2093902610
- Cited by
- 577
- References
- 1
- FWCI
- 11.96
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
