Replication and protection of telomeres

Verdun, Ramiro E., Karlseder, Jan·2007·Nature

DOI 10.1038/nature05976

Cited by (461)

Items 101–200 of 461

Telomerase reverse transcriptase in the regulation of gene expression
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Targeting telomerase and telomeres to enhance ionizing radiation effects in in vitro and in vivo cancer models
Francesco Berardinelli, Elisa Coluzzi, Antonella Sgura, Antonio Antoccia · 2017 · Mutation Research/Reviews in Mutation Research
A Protein Array Screen for Kaposi's Sarcoma-Associated Herpesvirus LANA Interactors Links LANA to TIP60, PP2A Activity, and Telomere Shortening
Meir Shamay, Jianyong Liu, Renfeng Li, Gangling Liao, Shen Li, Melanie Greenway, Shaohui Hu, Jian Kang Zhu, Zhi Xie, Richard F. Ambinder et al. · 2012 · Journal of Virology
Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis
P Gu, Y Wang, Kamlesh Kumar Bisht, L Wu, Lidiya Kukova, Eric M. Smith, Y Xiao, Susan M. Bailey, Ming Lei, Jayakrishnan Nandakumar et al. · 2016 · Oncogene
Telomere dynamics: the influence of folate and DNA methylation
Carly Jane Moores, Michael Felix Fenech, Nathan J. O’Callaghan · 2011 · Annals of the New York Academy of Sciences
Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection
Hyun Hee Yoo, In Kwon Chung · 2011 · Aging Cell
Cellular Stress and General Pathological Processes
Eugeny Yu. Gusev, Natalia V. Zotova · 2019 · Current Pharmaceutical Design
Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer
Mohammad Naser Taheri, Soudeh Ghafouri‐Fard, Sajad Najafi, Julia Kallenbach, Elmira Keramatfar, Golnaz Atri Roozbahani, Mehdi Heidari Horestani, Bashdar Mahmud Hussen, Aria Baniahmad · 2022 · Cancer Cell International
Telomeric armor: the layers of end protection
Liana Oganesian, Jan Karlseder · 2009 · Journal of Cell Science
In vitro lifespan and senescence mechanisms of human nucleus pulposus chondrocytes
Seo-Won Jeong, Jun‐Seok Lee, Ki-Won Kim · 2013 · The Spine Journal
Human Telomeric DNA Sequence-Specific Cleaving by G-Quadruplex Formation
Yan Xu, Yuta Suzuki, Tuomas Lönnberg, Makoto Komiyama · 2009 · Journal of the American Chemical Society
Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing
Pauline Billard, Delphine Poncet · 2019 · International Journal of Molecular Sciences
Discovery of Novel Schizocommunin Derivatives as Telomeric G-Quadruplex Ligands That Trigger Telomere Dysfunction and the Deoxyribonucleic Acid (DNA) Damage Response
Tong Che, Shuo-Bin Chen, Jia-Li Tu, Bo Wang, Yuqing Wang, Yan Zhang, Jing Wang, Zeng-qing Wang, Ze-Peng Zhang, Tian‐Miao Ou et al. · 2018 · Journal of Medicinal Chemistry
Telomerase Induction in HPV Infection and Oncogenesis
Rachel A. Katzenellenbogen · 2017 · Viruses
Photocrosslinking of human telomeric G-quadruplex loops by anti cyclobutane thymine dimer formation
Su, Dian G. T., Fang, Huafeng, Gross, Michael L., Taylor, John-Stephen A. · 2009 · Proceedings of the National Academy of Sciences
Osteoarthritis and telomere shortening
Łukasz Kuszel, Tomasz Trzeciak, Magdalena Richter, Malwina Czarny‐Ratajczak · 2014 · Journal of Applied Genetics
Hyper telomere recombination accelerates replicative senescence and may promote premature aging
Robert Tanner Hagelstrom, Krastan B. Blagoev, Laura J. Niedernhofer, Edwin H. Goodwin, Susan M. Bailey · 2010 · Proceedings of the National Academy of Sciences
Taming the tiger by the tail: modulation of DNA damage responses by telomeres
David A. Lydall · 2009 · The EMBO Journal
SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1 Tpp1 to modulate shelterin–Stn1 interaction in fission yeast
Keisuke Miyagawa, Ross S. Low, Venny Santosa, Hiroki Tsuji, Bettina A. Moser, Shiho Fujisawa, Jennifer L. Harland, Olga N. Raguimova, Andrew Go, Masaru Ueno et al. · 2014 · Proceedings of the National Academy of Sciences
Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance and Can be Safely Targeted for Telomerase Inhibition
Pedro Castelo‐Branco, Cindy Zhang, Tatiana Lipman, Mayumi Fujitani, Loen M. Hansford, Ian D. Clarke, Calvin B. Harley, Robert Tressler, David M. Malkin, Erin J. Walker et al. · 2011 · Clinical Cancer Research
A systems‐level approach to mapping the telomere length maintenance gene circuitry
Rafi Shachar, Lior Ungar, Martin Kupiec, Eytan Ruppin, Roded Sharan · 2008 · Molecular Systems Biology
Lead Exposure Induces Telomere Instability in Human Cells
Géraldine Pottier, Muriel Viau, Michelle Ricoul, Grace Shim, Marion Bellamy, Corina Cuceu, William M. Hempel, Laure Sabatier · 2013 · PLoS ONE
Telomerase inhibitors and ‘T-oligo’ as cancer therapeutics: contrasting molecular mechanisms of cytotoxicity
Andrew M. Rankin, Douglas V. Faller, Remco A. Spanjaard · 2008 · Anti-Cancer Drugs
The DNA secondary structures at telomeres and genome instability
Jun Jie Tan, Li Lan · 2020 · Cell & Bioscience
Ku is involved in cell growth, DNA replication and G1-S transition
Emmanouil Rampakakis, Domenic Di Paola, Maria Zannis‐Hadjopoulos · 2008 · Journal of Cell Science
Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ
Susan Jean Hsiao, Susan Harless Smith · 2009 · The Journal of Cell Biology
Nuclear pore complexes in the maintenance of genome integrity
Lucas Bukata, Stephanie L. Parker, Maximiliano A. D’Angelo · 2013 · Current Opinion in Cell Biology
Noncanonical DNA Secondary Structures as Drug Targets: the Prospect of the i‐Motif
Jussara Amato, Nunzia Iaccarino, Antonio Randazzo, Ettore Novellino, Bruno Pagano · 2014 · ChemMedChem
Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame
Arivazhagan Rajendran, Masayuki Endo, K. Hidaka, Phong Lan Thao Tran, Jean‐Louis Mergny, Hiroshi Sugiyama · 2013 · Nucleic Acids Research
Parameters Affecting Telomere-Mediated Chromosomal Truncation in Arabidopsis
Andrew D. L. Nelson, Jonathan C. Lamb, Pierre S. Kobrossly, Dorothy E. Shippen · 2011 · The Plant Cell
Role of ATM in the telomere response to the G-quadruplex ligand 360A
Gaëlle Pennarun, Christine Granotier-Beckers, Françoise Hoffschir, Eliane Mandine, Denis S.F. Biard, Laurent Gauthier, François Dominique Boussin · 2008 · Nucleic Acids Research
Clinical Relevance of Telomere Status and Telomerase Activity in Colorectal Cancer
Tamara Fernández‐Marcelo, Andrés Sánchez-Pernaute, Irene Pinedo Pascua, Carmen de Juan, Jacqueline Head, Antonio-José Torres, Pilar Iniesta · 2016 · PLoS ONE
Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status
Tamara Fernández‐Marcelo, Ana María Gómez, Irene Pinedo Pascua, Carmen de Juan, Jacqueline Head, Florentino Hernándo, J.R. Jarabo, Joaquín Calatayud, Antonio-José Torres, Pilar Iniesta · 2015 · Journal of Experimental & Clinical Cancer Research
Telomeres and atherosclerosis : review article
Sajidah Khan, Anil Amichund Chuturgoon, Datshana Prakash Naidoo · 2012 · Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa
Stable Lariat Formation Based on a G-Quadruplex Scaffold
Yan Xu, Hiroyuki Sato, Yuta Sannohe, Ken‐ichi Shinohara, Hiroshi Sugiyama · 2008 · Journal of the American Chemical Society
Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death
Laurent Gauthier, Christine Granotier-Beckers, Françoise Hoffschir, Olivier Etienne, Ali Ayouaz, Chantal Desmaze, Patrick Mailliet, Denis S.F. Biard, François Dominique Boussin · 2011 · Cellular and Molecular Life Sciences
The Breast Cancer Susceptibility Gene BRCA2 Is Required for the Maintenance of Telomere Homeostasis
Jaewon Min, Eun Shik Choi, Kwangwoo Hwang, Jimi Kim, Srihari C. Sampath, Ashok R. Venkitaraman, Hyun‐Sook Lee · 2011 · Journal of Biological Chemistry
BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence
Keith Wheaton, Jennifer Muir, Weili Ma, Samuel Benchimol · 2010 · Aging Cell
Telomeres and viruses: common themes of genome maintenance
Zhong Deng, Zhuo Wang, Paul M. Lieberman · 2012 · Frontiers in Oncology
ATM-like kinases and regulation of telomerase: lessons from yeast and mammals
Michelle Sabourin, Virginia A. Zakian · 2008 · Trends in Cell Biology
Understanding Ligand Interaction with Different Structures of G-Quadruplex DNA: Evidence of Kinetically Controlled Ligand Binding and Binding-Mode Assisted Quadruplex Structure Alteration
Sachin Dev Verma, Nibedita Pal, Moirangthem Kiran Singh, Him Shweta, Mohammad Firoz Khan, Sobhan Sen · 2012 · Analytical Chemistry
Logic gates based on G-quadruplexes: principles and sensor applications
Yahui Guo, Weirong Yao, Yunfei Xie, Xiaodong Zhou, Jiming Hu, Renjun Pei · 2015 · Microchimica Acta
DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation
Justin D Lormand, Noah A. Buncher, Connor T. Murphy, Parminder Kaur, Marietta Y. Lee, Peter Burgers, Hong Wang, Thomas A. Kunkel, Patricia Lynn Opresko · 2013 · Nucleic Acids Research
The telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas
Dong Qian, Bin Zhang, Liru He, Muyan Cai, Shi‐Juan Mai, Yi-Ji Liao, Yan‐Hui Liu, Marie C.M. Lin, Xiu‐Wu Bian, Yi‐Xin Zeng et al. · 2013 · The Journal of Pathology
Targeting the telosome: Therapeutic implications
Marco Folini, Paolo Gandellini, Nadia Zaffaroni · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Exploring the Dynamics of Propeller Loops in Human Telomeric DNA Quadruplexes Using Atomistic Simulations
Barira Islam, Petr Stadlbauer, Alejandro Gil-Ley, Guillermo Pérez‐Hernández, Shozeb M Haider, Stephen Neidle, Giovanni Bussi, Pavel Banáš, Michal Otyepka, Jiří Šponer · 2017 · Journal of Chemical Theory and Computation
Diminished Telomeric 3′ Overhangs Are Associated with Telomere Dysfunction in Hoyeraal-Hreidarsson Syndrome
Noa Lamm, Ordan Elly, Rotem Shponkin, Carmelit Richler, Memet Aker, Yehuda Tzfati · 2009 · PLoS ONE
Mesenchymal stem cells-based therapy as a potential treatment in neurodegenerative disorders: is the escape from senescence an answer?
Alessandro Castorina, Marta Anna Szychlinska, Rubina Marzagalli, Giuseppe Musumeci · 2015 · Neural Regeneration Research
Human subtelomeric copy number gains suggest a DNA replication mechanism for formation: beyond breakage–fusion–bridge for telomere stabilization
Svetlana A. Yatsenko, Patricia M. Hixson, Erin K. Roney, Daryl A. Scott, Christian Patrick Schaaf, Yu‐Tze Ng, Robbin Palmer, Richard B. Fisher, Ankita Patel, Sau Wai Cheung et al. · 2012 · Human Genetics
Human RECQL1 participates in telomere maintenance
Venkateswarlu Popuri, Joseph K. Hsu, Prabhat Khadka, Kent Horvath, Yie Liu, Deborah L. Croteau, Vilhelm A. Bohr · 2014 · Nucleic Acids Research
Telomeres and Telomerase in Renal Health
Lauren P. Wills, Rick G. Schnellmann · 2011 · Journal of the American Society of Nephrology
Nucleolar and coiled-body phosphoprotein 1 (NOLC1) regulates the nucleolar retention of TRF2
Fuwen Yuan, Guodong Li, Tanjun Tong · 2017 · Cell Death Discovery
Survival and Growth of Yeast without Telomere Capping by Cdc13 in the Absence of Sgs1, Exo1, and Rad9
Hien-Ping Ngo, David A. Lydall · 2010 · PLoS Genetics
Association Between Telomere Length, Chronic Kidney Disease, and Renal Traits: A Systematic Review
Oluwatoyin Idaomeh Ameh, Ikechi Gareth Okpechi, Collet Dandara, André Pascal Kengne · 2017 · OMICS A Journal of Integrative Biology
MiR-155 deficiency protects renal tubular epithelial cells from telomeric and genomic DNA damage in cisplatin-induced acute kidney injury
Qing Yin, Yajie Zhao, Wei‐Jie Ni, Tao‐Tao Tang, Yao Wang, Jing-Yuan Cao, Di Yin, Yi Wen, Zuo‐Lin Li, Yilin Zhang et al. · 2022 · Theranostics
Fission Yeast Shelterin Regulates DNA Polymerases and Rad3ATR Kinase to Limit Telomere Extension
Ya-Ting Chang, Bettina A. Moser, Toru Nakamura · 2013 · PLoS Genetics
C-Linked 8-aryl guanine nucleobase adducts: biological outcomes and utility as fluorescent probes
Richard A. Manderville, Stacey D. Wetmore · 2016 · Chemical Science
Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline
Aarón Méndez-Bermúdez, Mark Hills, Hilda A. Pickett, Anh Tuân Phan, Jean‐Louis Mergny, Jean‐François Riou, Nicola J. Royle · 2009 · Nucleic Acids Research
Recombination-Based Telomere Maintenance Is Dependent on Tel1-MRN and Rap1 and Inhibited by Telomerase, Taz1, and Ku in Fission Yeast
Lakxmi Subramanian, Bettina A. Moser, Toru Nakamura · 2007 · Molecular and Cellular Biology
Cellular senescence of white blood cells in very long-term survivors after allogeneic hematopoietic stem cell transplantation: the role of chronic graft-versus-host disease and female donor sex
Gabriela Maria Baerlocher, Alicia Rovó, Astrid Müller, Sybille Matthey, Martin Stern, Jörg P. Halter, Dominik A. Heim, Johannes R. Rischewski, Alois A. Gratwohl, André Tichelli · 2009 · Blood
Differing patterns of peripheral blood leukocyte telomere length in rheumatologic diseases
María Tamayo, Alejandro Mosquera, Ignacio Rego‐Pérez, JOSÉ LUIS FERNÁNDEZ-SUEIRO, Francisco Javier Blanco, José Luís Fernández · 2009 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
Role of telomeres in vascular senescence
Tohru Minamino · 2007 · Frontiers in bioscience
Ovarian aging and infertility
Monika Szafarowska, Małgorzata Maria Jerzak · 2013 · Ginekologia Polska
PARP is involved in replicative aging in Neurospora crassa
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The Connection Between Cell Fate and Telomere
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Profiles of telomeric repeats in Insecta reveal diverse forms of telomeric motifs in Hymenopterans
Yihang Zhou, Yi Wang, Xiao Xiong, Arthur G. Appel, Chao Zhang, Xu Wang · 2022 · Life Science Alliance
Conformation and Stability of Intramolecular Telomeric G-Quadruplexes: Sequence Effects in the Loops
Giovanna Sattin, Anna Artese, Matteo Nadai, Giosuè Costa, Lucia Parrotta, Stefano Alcaro, Manlio Palumbo, Sara N. Richter · 2013 · PLoS ONE
Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein
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Ruud W. J. Meijers · 2014 · World Journal of Nephrology
Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus
Silvia Giunco, Andrea Celeghin, Ketty Gianesin, Riccardo Dolcetti, Stefano Indraccolo, Anita De Rossi · 2015 · Cell Death and Disease
Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2
Parminder Kaur, Dong Wu, Jiangguo Lin, Preston J. Countryman, Kira Bradford, Dorothy A. Erie, Robert E. Riehn, Patricia Lynn Opresko, Hong Wang · 2016 · Scientific Reports
Pot1 inactivation leads to rampant telomere resection and loss in one cell cycle
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Junko Maëda, Charles R. Yurkon, Hiroshi Fujisawa, Masami Kaneko, Stefan C. Genet, Erica J. Roybal, Garrett W. Rota, Ethan R. Saffer, Barbara J. Rose, William H. Hanneman et al. · 2012 · PLoS ONE
c-Myc Quadruplex-forming Sequence Pu-27 Induces Extensive Damage in Both Telomeric and Nontelomeric Regions of DNA
Md Ashraful Islam, Shelia D. Thomas, Vundavalli V.V.S. Murty, Kara C. Sedoris, Donald Max Miller · 2014 · Journal of Biological Chemistry
p300-mediated acetylation of TRF2 is required for maintaining functional telomeres
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Jiangguo Lin, Preston J. Countryman, Haijiang Chen, Hai Pan, Yanlin Fan, Yunyun Jiang, Parminder Kaur, Wang Miao, Gisele Passador-Gurgel, Changjiang You et al. · 2016 · Nucleic Acids Research
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UNG protects B cells from AID-induced telomere loss
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Tpz1-Ccq1 and Tpz1-Poz1 Interactions within Fission Yeast Shelterin Modulate Ccq1 Thr93 Phosphorylation and Telomerase Recruitment
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Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage
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The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication
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Spatiotemporal analysis with a genetically encoded fluorescent RNA probe reveals TERRA function around telomeres
Toshimichi Yamada, Hideaki� Yoshimura, Rintaro Shimada, Mitsuru Hattori, Masatoshi Eguchi, Takahiro K Fujiwara, Akihiro Kusumi, Takeaki Ozawa · 2016 · Scientific Reports
Loss of Tumor Suppressor STAG2 Promotes Telomere Recombination and Extends the Replicative Lifespan of Normal Human Cells
Zharko Daniloski, Susan Harless Smith · 2017 · Cancer Research
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Disease-Associated Human Telomerase RNA Variants Show Loss of Function for Telomere Synthesis without Dominant-Negative Interference
Timothy M. Errington, Dragony Fu, Judy M.Y. Wong, Kathleen Collins · 2008 · Molecular and Cellular Biology
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Peter M. Lansdorp · 2017 · Blood Advances
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Cunzhi Lin, Gui‐Ling Xiang, Xinhong Zhu, Lulu Xiu, Jiaxing Sun, Xiao‐Yuan Zhang · 2018 · Oncology Letters
Telomere length dynamics over 10-years and related outcomes in patients with COPD
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Yucheng Xu, Kaijie He, Amir Goldkorn · 2011 · PubMed
DNA Damage Response Signals Transduce Stress From Rheumatoid Arthritis Risk Factors Into T Cell Dysfunction
Lan Shao · 2018 · Frontiers in Immunology