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Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

Scheuermann, Johanna C., de Ayala Alonso, Andrés Gaytán, Oktaba, Katarzyna, Ly-Hartig, Nga, McGinty, Robert K., Fraterman, Sven, Wilm, Matthias, Muir, Tom W., Müller, Jürg·2010·Nature
DOI 10.1038/nature08966PMC PMC3182123
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Research works printed but not linked: 38

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  9. Nijman, S. M. B. et al. A genomic and functional inventory of deubiquitinating enzymes. Cell 123, 773–786 (2005) · DOI · Paper page
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  12. Jensen, D. E. et al. BAP1: A novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. Oncogene 16, 1097–1112 (1998) · DOI
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  17. Oktaba, K. et al. Dynamic regulation by Polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila . Dev. Cell 15, 877–889 (2008) · DOI
  18. Gambetta, M. C., Oktaba, K. & Müller, J. Essential role of the glycosyltransferase Sxc/Ogt in Polycomb repression. Science 325, 93–96 (2009) · DOI · Paper page
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  27. McGinty, R. K. et al. Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B. ACS Chem. Biol. 4, 958–968 (2009) · DOI
  28. White, R. A. H. & Wilcox, M. Protein products of the Bithorax Complex in Drosophila . Cell 39, 163–171 (1984) · DOI
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  31. Nekrasov, M. et al. Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes. EMBO J. 26, 4078–4088 (2007) · DOI
  32. Fraterman, S., Zeiger, U., Khurana, T. S., Wilm, M. & Rubinstein, N. A. Quantitative proteomics profiling of sarcomere associated proteins in limb and extraocular muscle allotypes. Mol. Cell. Proteomics 6, 728–737 (2007) · DOI
  33. Müller, J. et al. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 111, 197–208 (2002) · DOI
  34. Francis, N. J., Saurin, A. J., Shao, Z. & Kingston, R. E. Reconstitution of a functional core polycomb repressive complex. Mol. Cell 8, 545–556 (2001) · DOI
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  36. Mason, D. E., Ek, J., Peters, E. C. & Harris, J. L. Substrate profiling of deubiquitin hydrolases with a positional scanning library and mass spectrometry. Biochem. 43, 6535–6544 (2004) · DOI
  37. Thåström, A. et al. Sequence motifs and free energies of selected natural and non-natural nucleosome positioning DNA sequences. J. Mol. Biol. 288, 213–229 (1999) · DOI
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Metadata

Authors
Scheuermann, J. C., de Ayala Alonso, A. G., Oktaba, K., Ly-Hartig, N., McGinty, R. K., Fraterman, S., Wilm, M., Muir, T. W., & Müller, J.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2010-05
Volume
465
Issue
7295
Pages
243-247
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/nature08966
PMC
PMC3182123
Cited by
792
References
2
Language
en
Licence
www.springer.com/tdm (tdm)

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