The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
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In the citing paper
“Tet2 is most widely appreciated for its gene activating function through its ability to oxidize 5-methylcytosine in DNA (38, 39).”
From Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction (2020) · cites this paper as [39]
In the citing paper
“Although Tet2 is an intrinsic repressor of myeloid leukaemia5”
From Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6 (2015) · cites this paper as [5]
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Citations
Cites
Human DNA methylomes at base resolution show widespread epigenomic differences
Lister, R., Pelizzola, M., Dowen, R. H., Hawkins, R. D., Hon, G., Tonti-Filippini, J., Nery, J. R., Lee, L., Ye, Z., Ngo, Q.-M., et al. (2009) · Nature · doi:10.1038/nature08514 · Cited by 4,673
Mutation in TET2 in Myeloid Cancers
Delhommeau, F., Dupont, S., Valle, V. D., James, C., Trannoy, S., Massé, A., Kosmider, O., Le Couedic, J.-P., Robert, F., Alberdi, A., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810069 · Cited by 1,776
Induction of tumors in mice by genomic hypomethylation
Gaudet, F., Hodgson, J. G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J. W., Leonhardt, H., & Jaenisch, R. (2003) · Science · doi:10.1126/science.1083558 · Cited by 1,499
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
Walsh, C. P., Chaillet, J. R., & Bestor, T. H. (1998) · Nature Genetics · doi:10.1038/2413 · Cited by 1,105
Research works printed but not linked: 22
- Tahiliani, M. et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930–935 (2009) · DOI · Paper page
- Iyer, L. M., Tahiliani, M., Rao, A. & Aravind, L. Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle 8, 1698–1710 (2009) · DOI
- Viguié, F. et al. Common 4q24 deletion in four cases of hematopoietic malignancy: early stem cell involvement? Leukemia 19, 1411–1415 (2005) · DOI
- Abdel-Wahab, O. et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood 114, 144–147 (2009) · DOI · Paper page
- Jankowska, A. M. et al. Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms. Blood 113, 6403–6410 (2009) · DOI · Paper page
- Langemeijer, S. M. et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nature Genet. 41, 838–842 (2009) · DOI · Paper page
- Levine, R. L. & Carroll, M. A common genetic mechanism in malignant bone marrow diseases. N. Engl. J. Med. 360, 2355–2357 (2009) · DOI
- Mullighan, C. G. TET2 mutations in myelodysplasia and myeloid malignancies. Nature Genet. 41, 766–767 (2009) · DOI
- Tefferi, A. et al. Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates. Leukemia 23, 900–904 (2009) · DOI
- Tefferi, A. et al. Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML. Leukemia 23, 1343–1345 (2009) · DOI
- Tefferi, A. et al. TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis. Leukemia 23, 905–911 (2009) · DOI
- Ito, S. et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466, 1129–1133 (2010) · DOI · Paper page
- Hayatsu, H. & Shiragami, M. Reaction of bisulfite with the 5-hydroxymethyl group in pyrimidines and in phage DNAs. Biochemistry 18, 632–637 (1979) · DOI
- Huang, Y. et al. The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. PLoS ONE 5, e8888 (2010) · DOI
- Tefferi, A. Epigenetic alterations and anti-epigenetic therapy in myelofibrosis. Leuk. Lymphoma 49, 2231–2232 (2008) · DOI
- Smith, L. T., Otterson, G. A. & Plass, C. Unraveling the epigenetic code of cancer for therapy. Trends Genet. 23, 449–456 (2007) · DOI
- Esteller, M. Epigenetics in cancer. N. Engl. J. Med. 358, 1148–1159 (2008) · DOI
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- Ehrlich, M. DNA hypomethylation in cancer cells. Epigenomics 1, 239–259 (2009) · DOI
- Lengauer, C. Cancer. An unstable liaison. Science 300, 442–443 (2003) · DOI
- Bröske, A.-M. et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nature Genet. 41, 1207–1215 (2009) · DOI · Paper page
- Jiang, Y. et al. Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. Blood 113, 1315–1325 (2009) · DOI · Paper page
Cited by
CpG islands and the regulation of transcription
Deaton, A. M., & Bird, A. (2011) · Genes & Development · doi:10.1101/gad.2037511 · Cited by 3,187
Function and information content of DNA methylation
Schübeler, D. (2015) · Nature · doi:10.1038/nature14192 · Cited by 2,060
TET-mediated active DNA demethylation: mechanism, function and beyond
Wu, X., & Zhang, Y. (2017) · Nature Reviews Genetics · doi:10.1038/nrg.2017.33 · Cited by 1,661
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
Bejar, R., Stevenson, K., Abdel-Wahab, O., Galili, N., Nilsson, B., Garcia-Manero, G., Kantarjian, H., Raza, A., Levine, R. L., Neuberg, D., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1013343 · Cited by 1,627
TET enzymes, TDG and the dynamics of DNA demethylation
Kohli, R. M., & Zhang, Y. (2013) · Nature · doi:10.1038/nature12750 · Cited by 1,623
Metadata
- Authors
- Ko, M., Huang, Y., Jankowska, A. M., Pape, U. J., Tahiliani, M., Bandukwala, H. S., An, J., Lamperti, E. D., Koh, K. P., Ganetzky, R., Liu, X. S., Aravind, L., Agarwal, S., Maciejewski, J. P., & Rao, A.
- Venue
- Nature
- Published
- 2010-12
- Volume
- 468
- Issue
- 7325
- Pages
- 839-843
- ISSN
- 0028-0836
- 1476-4687
- PMC
- PMC3003755
- Cited by
- 1,213
- References
- 4
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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- The paper
- Ko, M., Huang, Y., Jankowska, A. M., Pape, U. J., Tahiliani, M., Bandukwala, H. S., An, J., Lamperti, E. D., Koh, K. P., Ganetzky, R., Liu, X. S., Aravind, L., Agarwal, S., Maciejewski, J. P., & Rao, A. (2010). Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature. https://doi.org/10.1038/nature09586