Cited by 1,577Advanced MRI Techniques and ApplicationsAdvanced NMR Techniques and ApplicationsNMR spectroscopy and applications

Magnetic resonance fingerprinting

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Ma, Dan, Gulani, Vikas, Seiberlich, Nicole, Liu, Kecheng, Sunshine, Jeffrey L., Duerk, Jeffrey L., Griswold, Mark A.·2013·Nature

Abstract

Magnetic resonance is an exceptionally powerful and versatile measurement technique. The basic structure of a magnetic resonance experiment has remained largely unchanged for almost 50 years, being mainly restricted to the qualitative probing of only a limited set of the properties that can in principle be accessed by this technique. Here we introduce an approach to data acquisition, post-processing and visualization--which we term 'magnetic resonance fingerprinting' (MRF)--that permits the simultaneous non-invasive quantification of multiple important properties of a material or tissue. MRF thus provides an alternative way to quantitatively detect and analyse complex changes that can represent physical alterations of a substance or early indicators of disease. MRF can also be used to identify the presence of a specific target material or tissue, which will increase the sensitivity, specificity and speed of a magnetic resonance study, and potentially lead to new diagnostic testing methodologies. When paired with an appropriate pattern-recognition algorithm, MRF inherently suppresses measurement errors and can thus improve measurement accuracy.

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  • Magnetic resonance fingerprinting (MRF) uses a pseudo-randomized acquisition that causes the signals from different tissues to have a unique signal evolution ('fingerprint') that is a function of the multiple material properties being investigated.

    “It uses a pseudo-randomized acquisition that causes the signals from different tissues to have a unique signal evolution ('fingerprint') that is a function of the multiple material properties being investigated.”

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Research works printed but not linked: 3

  1. [22]Stoecker T Vahedipour K Pracht E Brenner D Shah NJ Isotropic Mapping of T1, T2, and M0 with MP-DESS and Phase-Graph Data Fitting Proceedings 19th Scientific Meeting, International Society for Magnetic Resonance in Medicine 2011 19 2011
  2. [34]Hahn EL Spin Echoes Physical Review 1950 80 580 594
  3. [51]Riffe MJ Blaimer M Barkauskas KJ Duerk JL Griswold MA SNR Estimation in Fast Dynamic Imaging Using Bootstrapped Statistics 1 Proceedings 15th Scientific Meeting, International Society for Magnetic Resonance in Medicine 2007 15 1879

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Authors
Ma, D., Gulani, V., Seiberlich, N., Liu, K., Sunshine, J. L., Duerk, J. L., & Griswold, M. A.
Affiliations
  • Case Western Reserve University (US)
  • University Hospitals of Cleveland (US)
  • Siemens Healthcare (United States) (US)
Corresponding author
Griswold, Mark A.
Venue
Nature
Published
2013-03
Volume
495
Issue
7440
Pages
187-192
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W2144288697
Cited by
1,577
References
53
Citations by year
2026: 115 · 2025: 147 · 2024: 148 · 2023: 160 · 2022: 149 · 2021: 175 · 2020: 168 · 2019: 157 · 2018: 108 · 2017: 101 · 2016: 65 · 2015: 42 · 2014: 26 · 2013: 10 · 2012: 1
FWCI
36.92
Type
journal article
Language
en
Open access
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • OhioLink ETD Center (Ohio Library and Information Network) (submittedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
Funders
  • Agence Nationale de la Recherche (ANR-20-CE19-0030, ANR-11-INBS-0006, ANR-21-CE17-0028)
  • National Institutes of Health (KL2TR000440)
  • National Heart, Lung, and Blood Institute (R01HL094557)
  • National Center for Advancing Translational Sciences
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
  • Physical Sciences › Chemistry › Spectroscopy › Advanced NMR Techniques and Applications
  • Physical Sciences › Physics and Astronomy › Nuclear and High Energy Physics › NMR spectroscopy and applications
Keywords
magnetic resonance fingerprinting, quantitative MRI, pattern recognition, tissue characterization, disease detection, non-invasive measurement, nuclear magnetic resonance
MeSH terms
Algorithms, Diagnostic Tests, Routine, Humans, Motion, Magnetic Resonance Spectroscopy, Pattern Recognition, Automated, Research Design, Sensitivity and Specificity, Reproducibility of Results, Phantoms, Imaging

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