Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

Li, W., Moore, M. J., Vasilieva, N., Sui, J., Wong, S. K., Berne, M. A., Somasundaran, M., Sullivan, J. L., Luzuriaga, K., Greenough, T. C., et al. (2003) · Nature · doi:10.1038/nature02145 · Cited by 5,923

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

Zaki, A. M., van Boheemen, S., Bestebroer, T. M., Osterhaus, A. D. M. E., & Fouchier, R. A. M. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1211721 · Cited by 5,677

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

Kuba, K., Imai, Y., Rao, S., Gao, H., Guo, F., Guan, B., Huan, Y., Yang, P., Zhang, Y., Deng, W., et al. (2005) · Nature Medicine · doi:10.1038/nm1267 · Cited by 3,445

Bats Are Natural Reservoirs of SARS-Like Coronaviruses

Li, W., Shi, Z., Yu, M., Ren, W., Smith, C. S., Epstein, J. H., Wang, H., Crameri, G. S., Hú, Z., Zhang, H., et al. (2005) · Science · doi:10.1126/science.1118391 · Cited by 2,571

Angiotensin-converting enzyme 2 protects from severe acute lung failure

Imai, Y., Kuba, K., Rao, S., Huan, Y., Guo, F., Guan, B., Yang, P., Sarao, R., Wada, T., Leong-Poi, H., et al. (2005) · Nature · doi:10.1038/nature03712 · Cited by 2,453

Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor

Li, F., Li, W., Farzan, M., & Harrison, S. C. (2005) · Science · doi:10.1126/science.1116480 · Cited by 2,035

Coronavirus Pathogenesis and the Emerging Pathogen Severe Acute Respiratory Syndrome Coronavirus

Weiss, S. R., & Navas-Martin, S. (2005) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.69.4.635-664.2005 · Cited by 1,256

Severe acute respiratory syndrome

Peiris, M. J. S., Guan, Y., & Yuen, K. (2004) · Nature Medicine · doi:10.1038/nm1143 · Cited by 1,157

Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV

Lambeir, A.-M., Durinx, C., Scharpé, S., & De Meester, I. (2003) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/713609354 · Cited by 955

Human aminopeptidase N is a receptor for human coronavirus 229E

Yeager, C. L., Ashmun, R. A., Williams, R. K., Cardellichio, C. B., Shapiro, L. H., Look, A. T., & Holmes, K. V. (1992) · Nature · doi:10.1038/357420a0 · Cited by 941

Cutaneous Manifestations in Patients With COVID-19: Clinical Characteristics and Possible Pathophysiologic Mechanisms

González, F., Correa, C. I. C., & Peñaranda, E. (2021) · Actas Dermo-Sifiliográficas · doi:10.1016/j.adengl.2021.01.024 · Cited by 43

Could SARS‐CoV‐2 infection affect male fertility and sexuality?

Muti, N. D., Finocchi, F., Tossetta, G., Salvio, G., Cutini, M., Marzioni, D., & Balercia, G. (2022) · Apmis · doi:10.1111/apm.13210 · Cited by 43

The Endonucleolytic RNA Cleavage Function of nsp1 of Middle East Respiratory Syndrome Coronavirus Promotes the Production of Infectious Virus Particles in Specific Human Cell Lines

Nakagawa, K., Narayanan, K., Wada, M., Popov, V. L., Cajimat, M. N. B., Baric, R. S., & Makino, S. (2018) · Journal of Virology · doi:10.1128/jvi.01157-18 · Cited by 43

Risks Posed to Corneal Transplant Recipients by COVID-19-Affected Donors

Desautels, J. D., Moshirfar, M., Martheswaran, T., Shmunes, K. M., & Ronquillo, Y. C. (2020) · Ophthalmology and Therapy · doi:10.1007/s40123-020-00254-w · Cited by 43

Inflammation, Thrombosis, and Destruction: The Three-Headed Cerberus of Trauma- and SARS-CoV-2-Induced ARDS

Lupu, L., Palmer, A., & Huber-Lang, M. S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.584514 · Cited by 43

DPP-4 inhibition and COVID-19: From initial concerns to recent expectations

Scheen, A. J. (2020) · Diabetes & Metabolism · doi:10.1016/j.diabet.2020.11.005 · Cited by 43

MERS-CoV: epidemiology, molecular dynamics, therapeutics, and future challenges

Rabaan, A. A., Al-Ahmed, S. H., Sah, R., Alqumber, M. A. A., Haque, S., Patel, S. K., Pathak, M., Tiwari, R., Yatoo, M. I., Haq, A. U., et al. (2021) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/s12941-020-00414-7 · Cited by 43

Cytokine Storm Modulation in COVID-19: A Proposed Role for Vitamin D and DPP-4 Inhibitor Combination Therapy (VIDPP-4i)

Pinheiro, M. M., Fabbri, A., & Infante, M. (2021) · Immunotherapy · doi:10.2217/imt-2020-0349 · Cited by 43

Microbial Metabolites: The Emerging Hotspot of Antiviral Compounds as Potential Candidates to Avert Viral Pandemic Alike COVID-19

Raihan, T., Rabbee, M. F., Roy, P., Choudhury, S., Baek, K.-H., & Azad, A. K. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.732256 · Cited by 44

Emerging and Reemerging Infectious Disease Threats

KHABBAZ, R. F., Bell, B. P., Schuchat, A., Ostroff, S. M., Moseley, R. R., Levitt, A. M., & Hughes, J. M. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-4801-3.00014-x · Cited by 46

Middle East respiratory syndrome: current status and future prospects for vaccine development

Du, L., & Jiang, S. (2015) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.1092518 · Cited by 43

Chloroquine as a Potential Treatment and Prevention Measure for the 2019 Novel Coronavirus: A ReviewPreprint

Kearney, J. F. (2020) · Preprints.org · doi:10.20944/preprints202003.0275.v1 · Cited by 43

Role of inflammatory markers in corona virus disease (COVID-19) patients: A review

Upadhyay, J., Tiwari, N., & Ansari, M. N. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220939477 · Cited by 43

Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections

Ying, T., Li, H., Lu, L., Dimitrov, D. S., & Jiang, S. (2014) · Microbes and Infection · doi:10.1016/j.micinf.2014.11.008 · Cited by 42

Association between Use of Oral Anti-Diabetic Drugs and the Risk of Sepsis: A Nested Case-Control Study

Shih, C.-J., Wu, Y.-L., Chao, P.-W., Kuo, S., Yang, C., Li, S., Ou, S., & Chen, Y. (2015) · Scientific Reports · doi:10.1038/srep15260 · Cited by 42

Variations in Spike Glycoprotein Gene of MERS-CoV, South Korea, 2015

Kim, D.-W., Kim, Y.-J., Park, S. H., Yun, M.-R., Yang, J., Kang, H. J., Han, Y. W., Lee, H., Kim, H. M., Kim, H., et al. (2015) · Emerging infectious diseases · doi:10.3201/eid2201.151055 · Cited by 42

Enhanced Ability of Oligomeric Nanobodies Targeting MERS Coronavirus Receptor-Binding Domain

He, L., Tai, W., Li, J., Chen, Y., Gao, Y., Li, J., Sun, S., Zhou, Y., Du, L., & Zhao, G. (2019) · Viruses · doi:10.3390/v11020166 · Cited by 43

ACE2 as Drug Target of COVID-19 Virus Treatment, Simplified Updated Review

Mostafa‐Hedeab, G. (2020) · Reports of Biochemistry and Molecular Biology · doi:10.29252/rbmb.9.1.97 · Cited by 43

Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε

Wong, L.-Y. R., Ye, Z., Lui, P., Zheng, X., Yuan, S., Zhu, L., Fung, S., Yuen, K., Siu, K., Yeung, M. L., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1901489 · Cited by 42

State-of-the-Art of Nanodiagnostics and Nanotherapeutics against SARS-CoV-2

Derakhshan, M. A., Amani, A., & Majidi, R. F. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c22381 · Cited by 42

Coronaviridae: 100,000 Years of Emergence and Reemergence

Kasmi, Y., Khataby, K., Souiri, A., & Ennaji, M. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-819400-3.00007-7 · Cited by 41

Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection

Wei, J., Patil, A., Collings, C. K., Alfajaro, M. M., Liang, Y., Cai, W. L., Strine, M. S., Filler, R. B., DeWeirdt, P. C., Hanna, R. E., et al. (2023) · Nature Genetics · doi:10.1038/s41588-023-01307-z · Cited by 41

Lung ischemia reperfusion injury: the therapeutic role of dipeptidyl peptidase 4 inhibition

Beckers, P. A. J., Gielis, J. F., Schil, P. E. V., & Adriaensen, D. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.01.41 · Cited by 41

The Interaction between Nidovirales and Autophagy Components

Cong, Y., Verlhac, P., & Reggiori, F. (2017) · Viruses · doi:10.3390/v9070182 · Cited by 41

Middle East Respiratory Syndrome: Pathogenesis and Therapeutic Developments

Choudhry, H., Bakhrebah, M. A., Abdulaal, W. H., Zamzami, M. A., Baothman, O. A. S., Hassan, M., Zeyadi, M., Helmi, N. M., Alzahrani, F. A., Ali, A., et al. (2019) · Future Virology · doi:10.2217/fvl-2018-0201 · Cited by 41

SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges

Soufi, G. J., Hekmatnia, A., Nasrollahzadeh, M., Shafiei, N., Sajjadi, M., Iravani, P., Fallah, S., Iravani, S., & Varma, R. S. (2020) · Applied Sciences · doi:10.3390/app10103641 · Cited by 41

4,4′-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor

Lee, J., An, H. K., Sohn, M.-G., Kivela, P. D., & Oh, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21175953 · Cited by 41

The recent outbreaks of human coronaviruses: A medicinal chemistry perspective

Pillaiyar, T., Wendt, L. L., Manickam, M., & Easwaran, M. (2020) · Medicinal Research Reviews · doi:10.1002/med.21724 · Cited by 43

Dipeptidyl‐peptidases: Key enzymes producing entry forms of extracellular proteins in asaccharolytic periodontopathic bacterium Porphyromonas gingivalis

Nemoto, T., & Ohara‐Nemoto, Y. (2020) · Molecular Oral Microbiology · doi:10.1111/omi.12317 · Cited by 42

How SARS-CoV-2 (COVID-19) spreads within infected hosts — what we know so far

Sanyal, S. (2020) · Emerging Topics in Life Sciences · doi:10.1042/etls20200165 · Cited by 44

Possible Link between SARS-CoV-2 Infection and Parkinson’s Disease: The Role of Toll-Like Receptor 4

Conte, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22137135 · Cited by 42

Man-Specific Lectins from Plants, Fungi, Algae and Cyanobacteria, as Potential Blockers for SARS-CoV, MERS-CoV and SARS-CoV-2 (COVID-19) Coronaviruses: Biomedical Perspectives

Barre, A., Damme, E. J. M. V., Simplicien, M., Poder, S. L., Klonjkowski, B., Benoist, H., Peyrade, D., & Rougé, P. (2021) · Cells · doi:10.3390/cells10071619 · Cited by 41

Middle East Respiratory Syndrome (MERS)

Rasmussen, S. A., Watson, A. K., & Swerdlow, D. L. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.ei10-0020-2016 · Cited by 40

Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus

Iwata‐Yoshikawa, N., Okamura, T., Shimizu, Y., Kotani, O., Sato, H., Sekimukai, H., Fukushi, S., Suzuki, T., Sato, Y., Takeda, M., et al. (2019) · Journal of Virology · doi:10.1128/jvi.01818-18 · Cited by 40

Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2

Saso, W., Yamasaki, M., Nakakita, S., Fukushi, S., Tsuchimoto, K., Watanabe, N., Sriwilaijaroen, N., Kanie, O., Muramatsu, M., Takahashi, Y., et al. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010590 · Cited by 40

Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains

Roelle, S. M., Shukla, N., Pham, A. T., Bruchez, A. M., & Matreyek, K. A. (2022) · PLoS Biology · doi:10.1371/journal.pbio.3001738 · Cited by 40

Withania somnifera (L.) Dunal (Ashwagandha) for the possible therapeutics and clinical management of SARS-CoV-2 infection: Plant-based drug discovery and targeted therapy

Singh, M., Jayant, K., Singh, D., Bhutani, S., Poddar, N. K., Chaudhary, A. A., Khan, S.-U.-D., Adnan, M., Siddiqui, A. J., Hassan, M. I., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.933824 · Cited by 41

Genome based evolutionary lineage of SARS-CoV-2 towards the development of novel chimeric vaccine

Akhand, M. R. N., Azim, K. F., Hoque, S. F., Moli, M. A., Joy, B. D., Akter, H., Afif, I. K., Ahmed, N., & Hasan, M. (2020) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2020.104517 · Cited by 39

Identification of vaccine targets & design of vaccine against SARS-CoV-2 coronavirus using computational and deep learning-based approaches

Abbasi, B. A., Saraf, D., Sharma, T., Sinha, R., Singh, S., Sood, S., Gupta, P., Gupta, A., Mishra, K., Kumari, P., et al. (2022) · PeerJ · doi:10.7717/peerj.13380 · Cited by 39

The Role of Dipeptidyl Peptidase – 4 Inhibitors in Diabetic Kidney Disease

Panchapakesan, U., & Pollock, C. A. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00443 · Cited by 39

Influence of hydrophobic and electrostatic residues on SARS‐coronavirus S2 protein stability: Insights into mechanisms of general viral fusion and inhibitor design

Aydin, H., Al‐Khooly, D., & Lee, J. E. (2014) · Protein Science · doi:10.1002/pro.2442 · Cited by 39

Inhibition of Proprotein Convertases Abrogates Processing of the Middle Eastern Respiratory Syndrome Coronavirus Spike Protein in Infected Cells but Does Not Reduce Viral Infectivity

Gierer, S., Müller, M. A., Heurich, A., Ritz, D., Springstein, B. L., Karsten, C. B., Schendzielorz, A. B., Gnirß, K., Drosten, C., & Pöhlmann, S. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu407 · Cited by 39

Genetic Dissection of the Host Tropism of Human-Tropic Pathogens

Douam, F., Gaska, J. M., Winer, B. Y., Ding, Q., von Schaewen, M., & Ploß, A. (2015) · Annual Review of Genetics · doi:10.1146/annurev-genet-112414-054823 · Cited by 39

Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4

Haverkamp, A.-K., Lehmbecker, A., Spitzbarth, I., Widagdo, W., Haagmans, B. L., Segalés, J., Vergara‐Alert, J., Bensaïd, A., van den Brand, J. M. A., Osterhaus, A. D. M. E., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-28109-2 · Cited by 39

A Fusion Peptide in the Spike Protein of MERS Coronavirus

Alsaadi, E. A. J., Neuman, B. W., & Jones, I. M. (2019) · Viruses · doi:10.3390/v11090825 · Cited by 39

Drug repurposing approach to combating coronavirus: Potential drugs and drug targets

Xu, J., Xue, Y., Zhou, R., Shi, P., Li, H., & Zhou, J. (2020) · Medicinal Research Reviews · doi:10.1002/med.21763 · Cited by 40

SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells

Wang, J., Yang, G., Wang, X., Wen, Z., Shuai, L., Luo, J. D., Wang, C., Sun, Z., Liu, R., Ge, J., et al. (2021) · Cell Discovery · doi:10.1038/s41421-021-00357-z · Cited by 39

Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine target

Veljković, V., Vergara‐Alert, J., Segalés, J., & Paessler, S. (2020) · F1000Research · doi:10.12688/f1000research.22149.4 · Cited by 38

SARS-CoV-2: the emergence of a viral pathogen causing havoc on human existence

Prasad, A., & Prasad, M. (2020) · Journal of Genetics · doi:10.1007/s12041-020-01205-x · Cited by 38

Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea

You, J. H., Lee, S. A., Chun, S., Song, S. O., Lee, B., Kim, D. J., & Boyko, E. J. (2020) · Endocrinology and Metabolism · doi:10.3803/enm.2020.787 · Cited by 38

A Novel Vision of Reinforcing Nanofibrous Masks with Metal Nanoparticles: Antiviral Mechanisms Investigation

Hadinejad, F., Morad, H., Jahanshahi, M., Zarrabi, A., Pazoki–Toroudi, H., & Mostafavi, E. (2023) · Advanced Fiber Materials · doi:10.1007/s42765-023-00275-7 · Cited by 39

Development of Monoclonal Antibody and Diagnostic Test for Middle East Respiratory Syndrome Coronavirus Using Cell-Free Synthesized Nucleocapsid Antigen

Yamaoka, Y., Matsuyama, S., Fukushi, S., Matsunaga, S., Matsushima, Y., Kuroyama, H., Kimura, H., Takeda, M., Chimuro, T., & Ryo, A. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00509 · Cited by 38

MERS Coronavirus: An Emerging Zoonotic Virus

Li, F., & Du, L. (2019) · Viruses · doi:10.3390/v11070663 · Cited by 38

Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors

Widagdo, W., Okba, N. M. A., Li, W., de Jong, A., de Swart, R. L., Begeman, L., van den Brand, J. M. A., Bosch, B., & Haagmans, B. L. (2019) · Journal of Virology · doi:10.1128/jvi.00107-19 · Cited by 38

Strategy, Progress, and Challenges of Drug Repurposing for Efficient Antiviral Discovery

Li, X., & Peng, T. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.660710 · Cited by 38

Inhibition of Viral Membrane Fusion by Peptides and Approaches to Peptide Design

Düzgüneş, N., Fernández‐Fuentes, N., & Konopka, K. (2021) · Pathogens · doi:10.3390/pathogens10121599 · Cited by 38

Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in Chronic Obstructive Pulmonary Disease

Osan, J. K., Talukdar, S. N., Feldmann, F., DeMontigny, B. A., Jerome, K., Bailey, K. L., Feldmann, H., & Mehedi, M. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.00459-22 · Cited by 38

Type 1 diabetes: A new vision of the disease based on endotypes

Weston, C. S., Boehm, B. O., & Pozzilli, P. (2024) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3770 · Cited by 40

A Small Region of Porcine Hemagglutinating Encephalomyelitis Virus Spike Protein Interacts with the Neural Cell Adhesion Molecule

Dong, B., Gao, W., Lu, H., Zhao, K., Ding, N., Liu, W., Zhao, J., Lan, Y., Tang, B., Zhao, J., et al. (2015) · Intervirology · doi:10.1159/000381060 · Cited by 37

Knowledge and Apprehension of Dental Patients about MERS-A Questionnaire Survey

Ashok, N. (2016) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2016/17519.7790 · Cited by 37

Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus

Sun, Y., Zhang, H., Shi, J. R., Zhang, Z., & Gong, R. (2017) · Viruses · doi:10.3390/v9090255 · Cited by 37

Immune response against epidemic coronaviruses

Pashenkov, M. V., & Khaitov, R. M. (2020) · Immunologiya · doi:10.33029/0206-4952-2020-41-1-5-18 · Cited by 37

Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections

Schlicht, K., Rohmann, N., Geisler, C., Hollstein, T., Knappe, C., Hartmann, K., Schwarz, J., Tran, F., Schunk, D., Junker, R., et al. (2020) · International Journal of Obesity · doi:10.1038/s41366-020-00689-y · Cited by 37

COVID-19 and vascular disorders (literature review)

Петрищев, Н. Н., Khalepo, O., Вавиленкова, Ю. А., & Vlasov, T. D. (2020) · Regional blood circulation and microcirculation · doi:10.24884/1682-6655-2020-19-3-90-98 · Cited by 40

Potential Treatment of COVID-19 with Traditional Chinese Medicine: What Herbs Can Help Win the Battle with SARS-CoV-2?

Li, L., Wu, Y. C., Wang, J., Yan, H., Lu, J., Wang, Y., Zhang, B., Zhang, J., Yang, J., Wang, X., et al. (2021) · Engineering · doi:10.1016/j.eng.2021.08.020 · Cited by 38

Middle East Respiratory Syndrome Coronavirus

Al‐Tawfiq, J. A., Azhar, E. I., Memish, Z. A., & Zumla, A. I. (2021) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0041-1733804 · Cited by 37

Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting

Hauser, B. M., Sangesland, M., Denis, K. S., Lam, E. C., Case, J. B., Windsor, I. W., Feldman, J. E., Caradonna, T. M., Kannegieter, T., Diamond, M., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110561 · Cited by 38

Non-insulin anti-diabetic agents in patients with type 2 diabetes and COVID-19: A Critical Appraisal of Literature

Singh, A. K., Singh, R., Saboo, B., & Misra, A. (2020) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2020.12.026 · Cited by 36

ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses

Catanzaro, N., Wu, Z., Fan, C., Jefferson, V. A., Abdelgadir, A., Schäfer, A., Yount, B. L., Björkman, P. J., Baric, R. S., & Letko, M. C. (2025) · Nature Communications · doi:10.1038/s41467-025-60286-3 · Cited by 38

Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium

Kasela, S., Ortega, V. E., Martorella, M., Garudadri, S., Nguyen, J., Ampleford, E., Pasanen, A., Nerella, S., Buschur, K. L., Barjaktarevic, I. Z., et al. (2021) · Genome Medicine · doi:10.1186/s13073-021-00866-2 · Cited by 37

Molecular screening of antimalarial, antiviral, anti-inflammatory and HIV protease inhibitors against spike glycoprotein of coronavirus

Prashantha, C. N., Gouthami, K., Lavanya, L., Bhavanam, S., Jakhar, A., Shakthiraju, R. G., Suraj, V., Sahana, K. V., Sujana, H. S., Guruprasad, N. M., et al. (2020) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2020.107769 · Cited by 40

Molecular characterization, pathogen-host interaction pathway and in silico approaches for vaccine design against COVID-19

Singh, N., Nand, S., Singh, V., & Singh, M. P. (2020) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2020.101874 · Cited by 37

Perspectives of Antidiabetic Drugs in Diabetes With Coronavirus Infections

Sun, B., Huang, S., & Zhou, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.592439 · Cited by 37

Adaptive Evolution of the Spike Protein in Coronaviruses

Tang, X., Qian, Z., Lu, X., & Lü, J. (2023) · Molecular Biology and Evolution · doi:10.1093/molbev/msad089 · Cited by 36

Treatment strategies for Middle East respiratory syndrome coronavirus

Modjarrad, K. (2016) · Journal of Virus Eradication · doi:10.1016/s2055-6640(20)30696-8 · Cited by 35

Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions

Martinez-Martín, N. (2017) · Journal of Immunology Research · doi:10.1155/2017/2197615 · Cited by 36

Reduction of soluble dipeptidyl peptidase 4 levels in plasma of patients infected with Middle East respiratory syndrome coronavirus

Inn, K., Kim, Y., Aigerim, A., Park, U., Hwang, E., Choi, M., Ys, K., & Cho, N. (2018) · Virology · doi:10.1016/j.virol.2018.03.015 · Cited by 35

Current understanding of middle east respiratory syndrome coronavirus infection in human and animal models

Wang, Y., Sun, J., Zhu, A., Zhao, J., & Zhao, J. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.03.80 · Cited by 36

SARS-CoV-2-host dynamics: Increased risk of adverse outcomes of COVID-19 in obesity

Yadav, R., Aggarwal, S., & Singh, A. (2020) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2020.07.030 · Cited by 36

Investigation of CD26, a potential SARS-CoV-2 receptor, as a biomarker of age and pathology

Raha, A. A., Chakraborty, S., Henderson, J. W., Mukaetova-Ladinska, E. B., Zaman, S. H., Trowsdale, J., & Raha‐Chowdhury, R. (2020) · Bioscience Reports · doi:10.1042/bsr20203092 · Cited by 35

Coronavirus-associated kidney outcomes in COVID-19, SARS, and MERS: a meta-analysis and systematic review

Zhou, S., Xu, J., Xue, C., Yang, B., Mao, Z., & Ong, A. C. M. (2020) · Renal Failure · doi:10.1080/0886022x.2020.1847724 · Cited by 37

Novel Molecular Evidence Related to COVID-19 in Patients with Diabetes Mellitus

Liao, Y., Zheng, J., Zheng, C., Lu, K., & Chao, Y. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9123962 · Cited by 35

Evaluation and characterization of HSPA5 (GRP78) expression profiles in normal individuals and cancer patients with COVID-19

Fu, J., Wei, C., He, J., Zhang, L., Zhou, J., Balaji, K. S., Shen, S., Peng, J., Sharma, A., & Fu, J. (2021) · International Journal of Biological Sciences · doi:10.7150/ijbs.54055 · Cited by 35

Aptamers—Diagnostic and Therapeutic Solution in SARS-CoV-2

Wandtke, T., Wędrowska, E., Szczur, M., Przybylski, G., Libura, M., & Kopiński, P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031412 · Cited by 38

Reduced COVID-19 Mortality With Sitagliptin Treatment? Weighing the Dissemination of Potentially Lifesaving Findings Against the Assurance of High Scientific Standards

Nauck, M. A., & Meier, J. J. (2020) · Diabetes Care · doi:10.2337/dci20-0062 · Cited by 34

Vaccines for emerging infectious diseases: Lessons from MERS coronavirus and Zika virus

Maslow, J. N. (2017) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2017.1358325 · Cited by 34

Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirusviainterferon-λin vitroand in mice

Sauerhering, L., Kupke, A., Meier, L., Dietzel, E., Hoppe, J., Gruber, A. D., Gattenloehner, S., Witte, B., Fink, L., Hofmann, N., et al. (2020) · European Respiratory Journal · doi:10.1183/13993003.01826-2019 · Cited by 34

Therapeutic Strategies in the Development of Anti-viral Drugs and Vaccines Against SARS-CoV-2 Infection

Bhatti, J. S., Bhatti, G. K., Khullar, N., Reddy, A. P., & Reddy, P. H. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02074-2 · Cited by 34

ACE2 partially dictates the host range and tropism of SARS-CoV-2

Gao, S., & Zhang, L. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.11.032 · Cited by 35

The use of Pseudotyped Coronaviruses for the Screening of Entry Inhibitors: Green Tea Extract Inhibits the Entry of SARS-CoV-1, MERSCoV, and SARS-CoV-2 by Blocking Receptor-spike Interaction

Joseph, J., Thankamani, K., Ajay, A., Raj, V. S., & Raj, V. S. (2021) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201022666210810111716 · Cited by 34

Emerging Viral Infections and the Potential Impact on Hypertension, Cardiovascular Disease, and Kidney Disease

Savedchuk, S., Raslan, R., Nystrom, S. E., & Sparks, M. A. (2022) · Circulation Research · doi:10.1161/circresaha.122.320873 · Cited by 34

Genome-Wide CRISPR/Cas9 Screen Reveals a Role for SLC35A1 in the Adsorption of Porcine Deltacoronavirus

Wang, X., Jin, Q., Xiao, W., Fang, P., Lai, L., Xiao, S., Wang, K., & Fang, L. (2022) · Journal of Virology · doi:10.1128/jvi.01626-22 · Cited by 37

Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging and re-emerging viruses

Wang, X., Zou, P., Wu, F., Lu, L., & Jiang, S. (2017) · Frontiers of Medicine · doi:10.1007/s11684-017-0589-5 · Cited by 34

Comparative highlights on MERS-CoV, SARS-CoV-1, SARS-CoV-2, and NEO-CoV

Goyal, R., Gautam, R. K., Chopra, H., Dubey, A. K., Singla, R. K., Rayan, R. Α., & Kamal, M. A. (2022) · EXCLI journal · doi:10.17179/excli2022-5355 · Cited by 38

Antiviral Effect of Lithium Chloride and Diammonium Glycyrrhizinate on Porcine Deltacoronavirus In Vitro

Zhai, X., Wang, S., Zhu, M., He, W., Pan, Z., & Su, S. (2019) · Pathogens · doi:10.3390/pathogens8030144 · Cited by 33

Association between COVID-19 and cardiovascular disease

Srivastava, K. (2020) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2020.100583 · Cited by 33

Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review

Barati, F., Pouresmaieli, M., Ekrami, E., Asghari, S., Ziarani, F. R., & Mamoudifard, M. (2020) · Biological Procedures Online · doi:10.1186/s12575-020-00129-1 · Cited by 33

Molecular targets for COVID-19 drug development: Enlightening Nigerians about the pandemic and future treatment

Muhammed, Y. (2020) · Biosafety and Health · doi:10.1016/j.bsheal.2020.07.002 · Cited by 33

2020 update on human coronaviruses: One health, one world

Zhao, X., Ding, Y., Du, J., & Fan, Y. (2020) · Medicine in Novel Technology and Devices · doi:10.1016/j.medntd.2020.100043 · Cited by 36

A Synthetic Peptide CTL Vaccine Targeting Nucleocapsid Confers Protection from SARS-CoV-2 Challenge in Rhesus Macaques

Harris, P. E., Brasel, T., Massey, C., Herst, C. V., Burkholz, S., Lloyd, P. M., Blankenberg, T., Bey, T. M., Carback, R. T., Hodge, T. W., et al. (2021) · Vaccines · doi:10.3390/vaccines9050520 · Cited by 33

Broad reception for coronavirus

Gallagher, T., & Perlman, S. M. (2013) · Nature · doi:10.1038/495176a · Cited by 32

Human Coronavirus EMC Is Not the Same as Severe Acute Respiratory Syndrome Coronavirus

Perlman, S. M., & Zhao, J. (2013) · mBio · doi:10.1128/mbio.00002-13 · Cited by 22

Human Coronavirus EMC Does Not Require the SARS-Coronavirus Receptor and Maintains Broad Replicative Capability in Mammalian Cell Lines

Müller, M. A., Raj, V. S., Muth, D., Meyer, B., Kallies, S., Smits, S. L., Wollny, R., Bestebroer, T. M., Specht, S., Suliman, T., et al. (2012) · mBio · doi:10.1128/mbio.00515-12 · Cited by 209

Putative conformations of the receptor-binding domain in S protein of hCoV-EMC in complex with its receptor dipeptidyl peptidase-4

Jiang, S., Lu, L., Du, L., & Debnath, A. K. (2013) · Journal of Infection · doi:10.1016/j.jinf.2013.04.007 · Cited by 12

The Emergence of Human Coronavirus EMC: How Scared Should We Be?

Chan, R. W. Y., & Poon, L. L. M. (2013) · mBio · doi:10.1128/mbio.00191-13 · Cited by 11