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The Dual Angiogenesis Effects via Nrf2/HO-1 Signaling Pathway of Melatonin Nanocomposite Scaffold on Promoting Diabetic Bone Defect Repair

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The role of photobiomodulation in accelerating bone repair

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Advanced Hybrid Strategies of GelMA Composite Hydrogels in Bone Defect Repair

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Enhancing angiogenesis and osseointegration through a double gyroid Ti6Al4V scaffold with triply periodic minimal surface

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Communication between endothelial cells and osteoblasts in regulation of bone homeostasis: Notch players

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Vascular endothelial growth factor signaling affects both angiogenesis and osteogenesis during the development of scleral ossicles

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Controlled Release of Bone Morphogenetic Protein-2 Augments the Coupling of Angiogenesis and Osteogenesis for Accelerating Mandibular Defect Repair

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Bone marrow lesions in osteoarthritis: From basic science to clinical implications

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Skeletal-Vascular Interactions in Bone Development, Homeostasis, and Pathological Destruction

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Four‐Arm Polymer‐Guided Formation of Curcumin‐Loaded Flower‐Like Porous Microspheres as Injectable Cell Carriers for Diabetic Wound Healing

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Functionalization of titanium implants using a modular system for binding and release of VEGF enhances bone‐implant contact in a rodent model

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Bone Marrow-Derived Stem Cells: a Mixed Blessing in the Multifaceted World of Diabetic Complications

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VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis

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Fibroblast contributes for osteoblastic phenotype in a MAPK-ERK and sonic hedgehog signaling-independent manner

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Mechanical microenvironment regulation of age-related diseases involving degeneration of human skeletal and cardiovascular systems

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Inhibition of VEGF gene expression in osteoblast cells by different NSAIDs

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Titanium-based implant comprising a porous microstructure assembled with nanoleaves and controllable silicon-ion release for enhanced osseointegration

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Emerging therapeutic targets for osteoporosis

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Radiation-induced multi-organ injury

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Exosome-capturing scaffold promotes endogenous bone regeneration through neutrophil-derived exosomes by enhancing fast vascularization.

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Bioinspired Synthetic Peptide-Based Biomaterials Regenerate Bone through Biomimicking of Extracellular Matrix

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An Injectable Black Phosphorus Hydrogel for Rapid Tooth Extraction Socket Healing

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The role of vascular and lymphatic networks in bone and joint homeostasis and pathology

Huang, J., Liao, C., Yang, J., & Zhang, L. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1465816 · Cited by 27

Krüppel‐like factors family in health and disease

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Inhibition of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-2 Facilitates CD31hiEndomucinhi Blood Vessel and Bone Formation in Ovariectomized Mice

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Single-cell and spatial transcriptomics approaches of the bone marrow microenvironment

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Mechanical–chemical coupled modeling of bone regeneration within a biodegradable polymer scaffold loaded with VEGF

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Is the cortical capillary renamed as the transcortical vessel in diaphyseal vascularity?

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Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARγ to inhibit NF‐κB signalling pathway

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Endogenous Glucocorticoid Metabolism in Bone: Friend or Foe

Martin, C., Cooper, M. S., & Hardy, R. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.733611 · Cited by 24

MIF does only marginally enhance the pro-regenerative capacities of DFO in a mouse-osteotomy-model of compromised bone healing conditions

Lang, A., Helfmeier, S., Stefanowski, J., Kuppe, A., Sunkara, V., Pfeiffenberger, M., Wolter, A., Damerau, A., Hemmati‐Sadeghi, S., Ringe, J., et al. (2021) · Bone · doi:10.1016/j.bone.2021.116247 · Cited by 24

Promoting osteointegration effect of Cu-alloyed titanium in ovariectomized rats

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Acacetin Prevents Bone Loss by Disrupting Osteoclast Formation and Promoting Type H Vessel Formation in Ovariectomy-Induced Osteoporosis

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Crosstalk between bone and other organs

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SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesis

Liu, Z., Liu, H., Liu, S., Li, B., Liu, Y., & Luo, E. (2024) · Cell Proliferation · doi:10.1111/cpr.13596 · Cited by 24

External Mechanical Stability Regulates Hematoma Vascularization in Bone Healing Rather than Endothelial YAP/TAZ Mechanotransduction

Mehl, J., Farahani, S. K., Brauer, E., Klaus‐Bergmann, A., Thiele, T., Ellinghaus, A., Bartels‐Klein, E., Koch, K., Schmidt‐Bleek, K., Petersen, A., et al. (2024) · Advanced Science · doi:10.1002/advs.202307050 · Cited by 23

Regional diversity in the murine cortical vascular network is revealed by synchrotron X-ray tomography and is amplified with age

Núñez, J., Goring, A., Javaheri, B., Razi, H., Gómez‐Nicola, D., Hesse, E., Pitsillides, A. A., Thurner, P. J., Schneider, P., & Clarkin, C. E. (2018) · European Cells and Materials · doi:10.22203/ecm.v035a20 · Cited by 24

Intravital optoacoustic and ultrasound bio-microscopy reveal radiation-inhibited skull angiogenesis

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Intermittent PTH Administration Increases Bone-Specific Blood Vessels and Surrounding Stromal Cells in Murine Long Bones

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Daidzein alleviates osteoporosis by promoting osteogenesis and angiogenesis coupling

Jia, J., He, R., Yao, Z.-L., Su, J., Deng, S., Chen, K., & Yu, B. (2023) · PeerJ · doi:10.7717/peerj.16121 · Cited by 22

Targeting type H vessels in bone‐related diseases

Xu, J., He, S., Xia, T., Shan, Y., & Wang, L. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.18123 · Cited by 23

Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration

Fan, S., Tan, Y., Yuan, X., Liu, C., Wu, X., Dai, T., Ni, S., Wang, J., Weng, Y., & Zhao, H. (2024) · Journal of Tissue Engineering · doi:10.1177/20417314241231452 · Cited by 22

Inhibition of sympathetic tone via hypothalamic descending pathway propagates glucocorticoid-induced endothelial impairment and osteonecrosis of the femoral head

Shao, W., Wang, B., Wang, P., Zhang, S., Gong, S., Guo, X., Duan, D., Shao, Z., Liu, W., He, L., et al. (2024) · Bone Research · doi:10.1038/s41413-024-00371-3 · Cited by 24

Ultrasound‐Responsive 4D Bioscaffold for Synergistic Sonopiezoelectric‐Gaseous Osteosarcoma Therapy and Enhanced Bone Regeneration

Fang, H., Zhu, D., Chen, Y., Zhang, C., Gan, L., Fang, Q., Chang, M., Chen, Y., & Gao, Y. (2025) · Advanced Science · doi:10.1002/advs.202417208 · Cited by 23

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

Zhan, C., Dai, Q., Ren, J., Jin, L., Wang, W., Ye, Z., Tsoi, J. K. H., & Lin, Y. (2025) · Advanced Science · doi:10.1002/advs.202506438 · Cited by 24

Strontium ranelate stimulates trabecular bone formation in a rat tibial bone defect healing process

Lavet, C., Mabilleau, G., Chappard, D., Rizzoli, R., & Ammann, P. (2017) · Osteoporosis International · doi:10.1007/s00198-017-4156-3 · Cited by 23

Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches

Das, P., Veazey, K. J., Van, H. T., Kaushik, S., Lin, K., Lu, Y., Ishii, M., Kikuta, J., Ge, K., Nussenzweig, A., et al. (2018) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1806019115 · Cited by 17

Efficiency of coculture with angiogenic cells or physiological BMP‐2 administration on improving osteogenic differentiation and bone formation of MSCs

Zhang, Y., Yang, W., Devit, A., & van den Beucken, J. J. J. P. (2018) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36581 · Cited by 23

Tibial growth plate vascularization is inhibited by the dithiocarbamate pesticide thiram in chickens: potential relationship to peripheral platelet counts alteration

Huang, S.-C., Li, L., Rehman, M. U., Gao, J., Zhang, L., Tong, X., Waqas, M., & Li, J. (2019) · Environmental Science and Pollution Research · doi:10.1007/s11356-019-06664-z · Cited by 22

The Application of Nanomaterials in Angiogenesis

Li, T., & Zhang, T. (2020) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x15666200211102203 · Cited by 23

Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease

Bersini, S., Drigo, R. A. E., Huang, L., Shokhirev, M. N., & Hetzer, M. W. (2020) · Advanced Biosystems · doi:10.1002/adbi.202000044 · Cited by 23

The Effect of MMP-2 Inhibitor 1 on Osteogenesis and Angiogenesis During Bone Regeneration

Jiang, L., Sheng, K., Wang, C., Xue, D., & Pan, Z. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.596783 · Cited by 23

Controlled delivery of bone morphogenic protein-2-related peptide from mineralised extracellular matrix-based scaffold induces bone regeneration

Meng, C., Su, W., Liu, M., Yao, S., Ding, Q., Yu, K., Xiong, Z., Chen, K., Guo, X., Bo, L., et al. (2021) · Materials Science and Engineering C · doi:10.1016/j.msec.2021.112182 · Cited by 23

Megakaryocyte Diversity in Ontogeny, Functions and Cell-Cell Interactions

Khatib-Massalha, E., & Méndez‐Ferrer, S. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.840044 · Cited by 26

Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF/RUNX2/OSX signaling axis

Shen, Z. Z., Dong, W., Chen, Z., Chen, G., Zhang, Y., Li, Z., Lin, H., Chen, H., Huang, M., Guo, Y., et al. (2022) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2022.5167 · Cited by 23

The emergence of the calvarial hematopoietic niche in health and disease

Mills, W. A., Coburn, M., & Eyo, U. B. (2022) · Immunological Reviews · doi:10.1111/imr.13120 · Cited by 23

Angiogenic stimulation strategies in bone tissue regeneration

Mahapatra, C., Kumar, P., Paul, M. K., & Kumar, A. (2022) · Tissue and Cell · doi:10.1016/j.tice.2022.101908 · Cited by 23

Metallic Nanoparticle-Doped Oxide Semiconductor Film for Bone Tumor Suppression and Bone Regeneration

Yao, M., Hao, X., Shao, H., Wang, D., Li, B., Xing, S., Zhao, X., Zhang, C., Liu, X., Zhang, Y. X., et al. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c10672 · Cited by 23

Curcumin Prevents Diabetic Osteoporosis through Promoting Osteogenesis and Angiogenesis Coupling via NF-κB Signaling

Fan, D., Lu, J., Yu, N., Xie, Y., & Lei, Z. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/4974343 · Cited by 23

Skeletal stem cells: origins, definitions, and functions in bone development and disease

Feng, H., Jiang, B., Xing, W., Sun, J., Greenblatt, M. B., & Zou, W. (2022) · Life Medicine · doi:10.1093/lifemedi/lnac048 · Cited by 24

MMP14 cleaves PTH1R in the chondrocyte-derived osteoblast lineage, curbing signaling intensity for proper bone anabolism

Chu, T. L., Chen, P., Yu, A. X., Kong, M., Tan, Z., Tsang, K. Y., Zhou, Z., & Cheah, K. S. E. (2023) · eLife · doi:10.7554/elife.82142 · Cited by 20

Regulation of hypoxic stress and oxidative stress in bone grafting: Current trends and future perspectives

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Cell-based mechanisms and strategies of co-culture system both in vivo and vitro for bone tissue engineering

Bi, M., Yang, K., Yu, T., Wu, G., & Li, Q. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115907 · Cited by 23

An in silico micro-multiphysics agent-based approach for simulating bone regeneration in a mouse femur defect model

Kendall, J. J., Ledoux, C., Marques, F. C., Boaretti, D., Schulte, F. A., Morgan, E. F., & Müller, R. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1289127 · Cited by 23

The bone-protective benefits of kaempferol combined with metformin by regulation of osteogenesis-angiogenesis coupling in OVX rats

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Research progress in the pathogenesis of hormone-induced femoral head necrosis based on microvessels: a systematic review

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Zhang, X., Chen, J., Pei, X., Yang, L., Wang, L., Chen, L., Yang, G., Pei, X., Wan, Q., & Wang, J. (2023) · Chinese Chemical Letters · doi:10.1016/j.cclet.2023.108889 · Cited by 23

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Endothelial diversity in bone vasculature coordinates osteogenesis and hematopoiesis

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