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Lithium fine tunes lipid membranes through phospholipid binding

Bunel, L., Adrien, V., Coleman, J., Heo, P., & Pincet, F. (2025) · Scientific Reports · doi:10.1038/s41598-025-97828-0 · Cited by 5

Mechanisms of Sustained Increases in γ Power Post-Ketamine in a Computational Model of the Hippocampal CA3: Implications for Ketamine’s Antidepressant Mechanism of Action

Petzi, M., Singh, S., Trappenberg, T. P., & Nunes, A. (2023) · Brain Sciences · doi:10.3390/brainsci13111562 · Cited by 5

The effects of bipolar disorder granule cell hyperexcitability and lithium therapy on pattern separation in a computational model of the dentate gyrus

Singh, S., Khayachi, A., Stern, S., Trappenberg, T. P., Alda, M., & Nunes, A. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03559-1 · Cited by 5

Targeting neuronal function for CNS drug discovery

Hempel, C. M., Werley, C. A., Dempsey, G. T., & Gerber, D. J. (2017) · Drug Discovery Today Technologies · doi:10.1016/j.ddtec.2017.03.005 · Cited by 5

Stem Cells to Inform the Neurobiology of Mental Illness

Johnstone, M., Hillary, R. F., & Clair, D. S. (2018) · Current topics in behavioral neurosciences · doi:10.1007/7854_2018_57 · Cited by 5

Catatonia associated with late-life psychosis successfully treated with lithium: a case report

Sugawara, H., Takamatsu, J., Hashimoto, M., & Ikeda, M. (2021) · Annals of General Psychiatry · doi:10.1186/s12991-021-00336-4 · Cited by 5

The conundrum of antidepressant use in bipolar disorder

Scaini, G., & Quevedo, J. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01930-y · Cited by 5

Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential

Shin, E., Nguyen, B.-T., Jeong, J. H., Nguyen, B.-C. H., Tran, N. K. C., Sharma, N., Kim, D.-J., Nah, S.-Y., Lichtstein, D., Nabeshima, T., et al. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112657 · Cited by 5

The Mood Stabilizer Lithium Slows Down Synaptic Vesicle Cycling at Glutamatergic Synapses

Tang, W., Cory, B., Lim, K., & Fivaz, M. L. (2022) · NeuroMolecular Medicine · doi:10.1007/s12017-022-08729-8 · Cited by 5

Chronic LiCl pretreatment suppresses thrombin‐stimulated intracellular calcium mobilization through TRPC 3 in astroglioma cells

Uemura, T., Green, M., & Warsh, J. J. (2016) · Bipolar Disorders · doi:10.1111/bdi.12447 · Cited by 5

SCN11A mRNA levels in female bipolar disorder PBMCs as tentative biomarker for distinct patient sub‐phenotypes

Voinsky, I., McCarthy, M. J., Shekhtman, T., Kelsoe, J. R., & Gurwitz, D. (2019) · Drug Development Research · doi:10.1002/ddr.21598 · Cited by 5

Lineage specification into GABAergic, glutamatergic, dopaminergic, and astrocytic phenotypes using MUSE stem cells: a novel approach for modeling neurodegenerative and psychiatric disorders

Aprile, D., Patrone, D., Sammarraie, S. H. A. A., Alessio, N., Peluso, G., Bernardo, G. D., & Galderisi, U. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03251-2 · Cited by 4

Lithium partially rescues gene expression and enhancer activity from heterozygous knockout of AKAP11 while inducing novel differential changes

Farhangdoost, N., Pietrantonio, A., Liu, Y., Liao, C., Rochefort, D. L., Pacis, A., Alda, M., Dion, P. A., Chaumette, B., Khayachi, A., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-21716-w · Cited by 4

A pilot study examining the impact of lithium treatment and responsiveness on mnemonic discrimination in bipolar disorder

Madanlal, D., Guinard, C., Nuñez, V. P., Becker, S., Garnham, J. S., Khayachi, A., Léger, S., O’Donovan, C., Singh, S., Stern, S., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.146 · Cited by 4

Predicted Cellular and Molecular Actions of Lithium in the Treatment of Bipolar Disorder: An In Silico Study

Najafi, H., Totonchi, M., & Sadeghizadeh, M. (2020) · CNS Drugs · doi:10.1007/s40263-020-00723-7 · Cited by 4

Investigation of genetic loci shared between bipolar disorder and risk-taking propensity: potential implications for pharmacological interventions

Pisanu, C., Congiu, D., Severino, G., Ardau, R., Chillotti, C., Zompo, M. D., Baune, B. T., & Squassina, A. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01045-y · Cited by 4

Neural progenitor cells derived from lithium responsive and non-responsive bipolar disorder patients exhibit distinct sensitivity to cell death following methamphetamine

Mishra, H. K., Mandyam, A. D., Trenet, W., Wei, H., Nievergelt, C. M., Maihofer, A. X., Shilling, P. D., Alda, M., Gershon, E. S., McInnis, M. G., et al. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109410 · Cited by 5

Gm527 deficiency in dentate gyrus improves memory through upregulating dopamine D1 receptor pathway

Jia, J., Peng, H., Tian, R. L., Zhou, H., Zheng, H., Liu, B., & Lu, Y. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14259 · Cited by 4

Putative biological predictors of treatment response in bipolar disorders

Gonzalez, S., Williams, A. J., Blacker, C. J., Voort, J. L. V., Schak, K. M., Nemeroff, C. B., Widge, A. S., & Tohen, M. F. (2016) · Personalized Medicine in Psychiatry · doi:10.1016/j.pmip.2016.11.003 · Cited by 5

Modelling lithium responsiveness in a dish

Whalley, K. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn4062 · Cited by 1

Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients’ responsiveness to lithium

Stern, S., Santos, R., Marchetto, M. C., Mendes, A. P. D., Rouleau, G. A., Biesmans, S., Wang, Q.-W., Yao, J., Charnay, P., Bang, A. G., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.260 · Cited by 169

Can Computational Modeling Predict Disease Phenotype?

Lopez-Lengowski, K., & Kathuria, A. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.04.015

Akt and AMPK activators rescue hyperexcitability in neurons from patients with bipolar disorder

Khayachi, A., Abuzgaya, M., Liu, Y., Jiao, C., Dejgaard, K., Schorova, L., Kamesh, A., He, Q., Cousineau, Y., Pietrantonio, A., et al. (2024) · EBioMedicine · doi:10.1016/j.ebiom.2024.105161 · Cited by 23

Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids

Osete, J. R., Akkouh, I. A., Ievglevskyi, O., Vandenberghe, M., de Assis, D. R., Ueland, T., Kondratskaya, E., Holen, B., Szabó, A., Hughes, T., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-01944-0 · Cited by 52