Gage, Fred H.

Neurogenesis in the adult human hippocampus

Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 6,369

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Naldini, L., Blömer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., & Trono, D. (1996) · Science

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 4,903

Mammalian neural stem cells.

Gage, F. H. (2000) · Science

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 4,786

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

van Praag, H., Kempermann, G., & Gage, F. H. (1999) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 3,880

Mechanisms underlying inflammation in neurodegeneration

Glass, C. K., Saijo, K., Winner, B., Marchetto, M. C., & Gage, F. H. (2010) · Cell

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 3,580

Mechanisms and Functional Implications of Adult Neurogenesis

Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 3,007

Running enhances neurogenesis, learning, and long-term potentiation in mice

van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 2,904

Functional neurogenesis in the adult hippocampus

van Praag, H., Schinder, A. F., Christie, B. R., Toni, N., Palmer, T. D., & Gage, F. H. (2002) · Nature

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 2,853

Neural consequences of enviromental enrichment

van Praag, H., Kempermann, G., & Gage, F. H. (2000) · Nature Reviews Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 2,468

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

Deng, W., Aimone, J. B., & Gage, F. H. (2010) · Nature reviews. Neuroscience

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 2,120

Exercise enhances learning and hippocampal neurogenesis in aged mice

van Praag, H., Shubert, T., Zhao, C., & Gage, F. H. (2005) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 2,078

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

Clelland, C. D., Choi, M., Romberg, C., Clemenson, G. D., Fragniere, A., Tyers, P., Jessberger, S., Saksida, L. M., Barker, R. A., Gage, F. H., et al. (2009) · Science

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,642

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

Naldini, L., Blömer, U., Gage, F. H., Trono, D., & Verma, I. M. (1996) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 1,499

Astroglia induce neurogenesis from adult neural stem cells

Song, H., Stevens, C. F., & Gage, F. H. (2002) · Nature

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 1,452

Modelling schizophrenia using human induced pluripotent stem cells

Brennand, K. J., Simone, A., Jou, J., Gelboin-Burkhart, C., Tran, N., Sangar, S., Li, Y., Mu, Y., Chen, G., Yu, D., et al. (2011) · Nature

Pluripotent Stem Cells ResearchSchizophrenia research and treatment

Cited by 1,375

An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus

Pereira, A. C., Huddleston, D. E., Brickman, A. M., Sosunov, A. A., Hen, R., McKhann, G. M., Sloan, R., Gage, F. H., Brown, T. R., & Small, S. A. (2007) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,353

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

Marchetto, M. C. N., Carromeu, C., Acab, A., Yu, D., Yeo, G. W., Mu, Y., Chen, G., Gage, F. H., & Muotri, A. R. (2010) · Cell

Genetics and Neurodevelopmental DisordersPluripotent Stem Cells Research

Cited by 1,329

Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus

Zhao, C., Teng, E. M., Summers, R. G., Ming, G.-L., & Gage, F. H. (2006) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 1,257

Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

Israel, M. A., Yuan, S. H., Bardy, C., Reyna, S. M., Mu, Y., Herrera, C., Hefferan, M. P., Van Gorp, S., Nazor, K. L., Boscolo, F. S., et al. (2012) · Nature

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 1,253

An environment-dependent transcriptional network specifies human microglia identity

Gosselin, D., Skola, D., Coufal, N. G., Holtman, I. R., Schlachetzki, J. C. M., Sajti, E., Jaeger, B. N., O’Connor, C., Fitzpatrick, C., Pasillas, M. P., et al. (2017) · Science

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 1,220

An in vivo model of functional and vascularized human brain organoids

Mansour, A. A., Gonçalves, J. T., Bloyd, C. W., Li, H., Fernandes, S., Quang, D., Johnston, S., Parylak, S. L., Jin, X., & Gage, F. H. (2018) · Nature Biotechnology

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 1,211

Development of a self-inactivating lentivirus vector

Miyoshi, H., Blömer, U., Takahashi, M., Gage, F. H., & Verma, I. M. (1998) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 1,196

Experience-Induced Neurogenesis in the Senescent Dentate Gyrus

Kempermann, G., Kuhn, H. G., & Gage, F. H. (1998) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,150

Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior

Gonçalves, J. T., Schafer, S. T., & Gage, F. H. (2016) · Cell

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,122