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Cited by 539

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

The promise of organ and tissue preservation to transform medicine

Open access
Giwa, Sebastian, Lewis, Jedediah K, Alvarez, Luis, Langer, Robert, Roth, Alvin E, Church, George M, Markmann, James F, Sachs, David H, Chandraker, Anil, Wertheim, Jason A, Rothblatt, Martine, Boyden, Edward S, Eidbo, Elling, Lee, W P Andrew, Pomahac, Bohdan, Brandacher, Gerald, Weinstock, David M, Elliott, Gloria, Nelson, David, Acker, Jason P, Uygun, Korkut, Schmalz, Boris, Weegman, Brad P, Tocchio, Alessandro, Fahy, Greg M, Storey, Kenneth B, Rubinsky, Boris, Bischof, John, Elliott, Janet A W, Woodruff, Teresa K, Morris, G John, Demirci, Utkan, Brockbank, Kelvin G M, Woods, Erik J, Ben, Robert N, Baust, John G, Gao, Dayong, Fuller, Barry, Rabin, Yoed, Kravitz, David C, Taylor, Michael J, Toner, Mehmet·2017·Nature Biotechnology

Abstract

The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create public health benefits on par with curing cancer. Unmet needs for organ and tissue preservation place enormous logistical limitations on transplantation, regenerative medicine, drug discovery, and a variety of rapidly advancing areas spanning biomedicine. A growing coalition of researchers, clinicians, advocacy organizations, academic institutions, and other stakeholders has assembled to address the unmet need for preservation advances, outlining remaining challenges and identifying areas of underinvestment and untapped opportunities. Meanwhile, recent discoveries provide proofs of principle for breakthroughs in a family of research areas surrounding biopreservation. These developments indicate that a new paradigm, integrating multiple existing preservation approaches and new technologies that have flourished in the past 10 years, could transform preservation research. Capitalizing on these opportunities will require engagement across many research areas and stakeholder groups. A coordinated effort is needed to expedite preservation advances that can transform several areas of medicine and medical science.

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Crossref · 10.1038/nbt.3889

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Metadata

Authors
Giwa, S., Lewis, J. K., Alvarez, L., Langer, R., Roth, A. E., Church, G. M., Markmann, J. F., Sachs, D. H., Chandraker, A., Wertheim, J. A., Rothblatt, M., Boyden, E. S., Eidbo, E., Lee, W. P. A., Pomahac, B., Brandacher, G., Weinstock, D. M., Elliott, G., Nelson, D., Acker, J. P., Uygun, K., Schmalz, B., Weegman, B. P., Tocchio, A., Fahy, G. M., Storey, K. B., Rubinsky, B., Bischof, J., Elliott, J. A. W., Woodruff, T. K., Morris, G. J., Demirci, U., Brockbank, K. G. M., Woods, E. J., Ben, R. N., Baust, J. G., Gao, D., Fuller, B., Rabin, Y., Kravitz, D. C., Taylor, M. J., & Toner, M.
Venue
Nature Biotechnology
Published
2017-06
Volume
35
Issue
6
Pages
530-542
ISSN
  • 0733-222X (ISSN-L)
  • 1087-0156
  • 1546-1696
OpenAlex
W2621460803
Cited by
539
References
10
FWCI
40.18
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The promise of organ and tissue preservation to transform medicine. https://app.cochat.ai/papers/10.1038/nbt.3889
The paper
Giwa, S., Lewis, J. K., Alvarez, L., Langer, R., Roth, A. E., Church, G. M., Markmann, J. F., Sachs, D. H., Chandraker, A., Wertheim, J. A., Rothblatt, M., Boyden, E. S., Eidbo, E., Lee, W. P. A., Pomahac, B., Brandacher, G., Weinstock, D. M., Elliott, G., Nelson, D., . . . Toner, M. (2017). The promise of organ and tissue preservation to transform medicine. Nature Biotechnology. https://doi.org/10.1038/nbt.3889

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.