TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends

Mammalian Telomeres End in a Large Duplex Loop

Griffith, J. D., Comeau, L., Rosenfield, S., Stansel, R. M., Bianchi, A., Moss, H., & de Lange, T. (1999) · Cell · doi:10.1016/s0092-8674(00)80760-6 · Cited by 2,447 · see citing works

How Shelterin Protects Mammalian Telomeres

Palm, W., & de Lange, T. (2008) · Annual Review of Genetics · doi:10.1146/annurev.genet.41.110306.130350 · Cited by 1,802 · see citing works

TRF2 Protects Human Telomeres from End-to-End Fusions

van Steensel, B., Smogorzewska, A., & de Lange, T. (1998) · Cell · doi:10.1016/s0092-8674(00)80932-0 · Cited by 1,709 · see citing works

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

McVey, M., & Lee, S. E. (2008) · Trends in Genetics · doi:10.1016/j.tig.2008.08.007 · Cited by 974 · see citing works

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1

Denchi, E. L., & de Lange, T. (2007) · Nature · doi:10.1038/nature06065 · Cited by 880 · see citing works

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

Wang, M., Wu, W., Wu, W., Rosidi, B., Zhang, L., Wang, H., & Iliakis, G. E. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl840 · Cited by 823 · see citing works

Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining

Mahaney, B. L., Meek, K., & Lees‐Miller, S. P. (2009) · Biochemical Journal · doi:10.1042/bj20080413 · Cited by 722 · see citing works

Cernunnos, a Novel Nonhomologous End-Joining Factor, Is Mutated in Human Immunodeficiency with Microcephaly

Buck, D., Malivert, L., de Chasseval, R., Barraud, A., Fondanèche, M.-C., Sanal, O., Plebani, A., Stéphan, J.-L., Hufnagel, M., le Deist, F., et al. (2006) · Cell · doi:10.1016/j.cell.2005.12.030 · Cited by 722 · see citing works

Involvement of Poly(ADP-ribose) Polymerase-1 and XRCC1/DNA Ligase III in an Alternative Route for DNA Double-strand Breaks Rejoining

Audebert, M., Salles, B., & Calsou, P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m404524200 · Cited by 709 · see citing works

DNA Repair in Mammalian Cells

Robertson, A. B., Klungland, A., Rognes, T., & Leiros, I. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-8736-z · Cited by 652 · see citing works

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

Celli, G. B., & de Lange, T. (2005) · Nature Cell Biology · doi:10.1038/ncb1275 · Cited by 623 · see citing works

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

Zhu, X., Küster, B., Mann, M., Petrini, J. H. J., & de Lange, T. (2000) · Nature Genetics · doi:10.1038/77139 · Cited by 602 · see citing works

The role of double-strand break repair — insights from human genetics

O’Driscoll, M., & Jeggo, P. A. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1746 · Cited by 581 · see citing works

Extensive allelic variation and ultrashort telomeres in senescent human cells

Baird, D. M., Rowson, J., Wynford-Thomas, D., & Kipling, D. (2003) · Nature Genetics · doi:10.1038/ng1084 · Cited by 570 · see citing works

Replication and protection of telomeres

Verdun, R. E., & Karlseder, J. (2007) · Nature · doi:10.1038/nature05976 · Cited by 463 · see citing works

How telomeres are replicated

Gilson, É., & Géli, V. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2259 · Cited by 454 · see citing works

Recent Expansion of the Telomeric Complex in Rodents: Two Distinct POT1 Proteins Protect Mouse Telomeres

Hockemeyer, D., Daniels, J.-P., Takai, H., & de Lange, T. (2006) · Cell · doi:10.1016/j.cell.2006.04.044 · Cited by 397 · see citing works

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

Bailey, S. M., Meyne, J., Chen, D. J., Kurimasa, A., Li, G. C., Lehnert, B. E., & Goodwin, E. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.14899 · Cited by 395 · see citing works

ERCC1/XPF Removes the 3′ Overhang from Uncapped Telomeres and Represses Formation of Telomeric DNA-Containing Double Minute Chromosomes

Zhu, X., Niedernhofer, L. J., Küster, B., Mann, M., Hoeijmakers, J. H. J., & de Lange, T. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00478-7 · Cited by 382 · see citing works

DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2

Smogorzewska, A., Karlseder, J., Holtgreve-Grez, H., Jauch, A. S., & de Lange, T. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01179-x · Cited by 377 · see citing works

DNA Ligase IV Is Essential for V(D)J Recombination and DNA Double-Strand Break Repair in Human Precursor Lymphocytes

Grawunder, U., Zimmer, D., Fugmann, S. D., Schwarz, K., & Lieber, M. R. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80147-1 · Cited by 367 · see citing works

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

Xie, A., Kwok, A., & Scully, R. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1640 · Cited by 351 · see citing works

DNA‐PK autophosphorylation facilitates Artemis endonuclease activity

Goodarzi, A. A., Yu, Y., Riballo, E., Douglas, P., Walker, S. A., Ye, R., Härer, C. J., Marchetti, C., MORRICE, N. A., Jeggo, P. A., et al. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601255 · Cited by 342 · see citing works

Ku acts in a unique way at the mammalian telomere to prevent end joiningPreprint

Hsu, H.-L., Gilley, D. P., Galande, S., Hande, M. P., Allen, B. L., Kim, S., Li, G. C., Campisi, J., Kohwi-shigematsu, T., & Chen, D. J. (2000) · Genes & Development · doi:10.1101/gad.844000 · Cited by 342 · see citing works

DNA Ligase III as a Candidate Component of Backup Pathways of Nonhomologous End Joining

Wang, H., Rosidi, B., Perrault, A. R., Wang, M., Zhang, L., Windhofer, F., & Iliakis, G. E. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3055 · Cited by 334 · see citing works

Ku is associated with the telomere in mammals

Hsu, H.-L., Gilley, D. P., Blackburn, E. H., & Chen, D. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.22.12454 · Cited by 327 · see citing works

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

Rass, E., Grabarz, A., Plo, I., Gautier, J., Bertrand, P., & López, B. S. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1641 · Cited by 325 · see citing works

DNA Repair in Mammalian Cells

Pardo, B., Gómez‐González, B., & Aguilera, A. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-8740-3 · Cited by 323 · see citing works

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

Celli, G. B., Denchi, E. L., & de Lange, T. (2006) · Nature Cell Biology · doi:10.1038/ncb1444 · Cited by 320 · see citing works

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G‐strand overhang

Samper, E., Goytisolo, F. A., Slijepčević, P., van Buul, P. P. W., & Blasco, M. A. (2000) · EMBO Reports · doi:10.1093/embo-reports/kvd051 · Cited by 317 · see citing works

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double‐strand breaks

Ramsden, D. A., & Gellert, M. (1998) · The EMBO Journal · doi:10.1093/emboj/17.2.609 · Cited by 296 · see citing works

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

d'Adda di Fagagna, F., Hande, M. P., Tong, W.-M., Roth, D., Lansdorp, P. M., Wang, Z.-Q., & Jackson, S. P. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00328-1 · Cited by 293 · see citing works

The DNA-dependent Protein Kinase Is Inactivated by Autophosphorylation of the Catalytic Subunit

Chan, D. W., & Lees‐Miller, S. P. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.15.8936 · Cited by 291 · see citing works

Chapter 2 DNA-PK

Meek, K., Dang, V. D., & Lees‐Miller, S. P. (2008) · Advances in immunology · doi:10.1016/s0065-2776(08)00602-0 · Cited by 271 · see citing works

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

Hammarsten, O., & Chu, G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.2.525 · Cited by 238 · see citing works

Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein

Yoo, S. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.24.4679 · Cited by 228 · see citing works

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres

Espejel, S., Franco, S., Rodríguez, S., Bouffler, S. D., Cigudosa, J. C., & Blasco, M. A. (2002) · The EMBO Journal · doi:10.1093/emboj/21.9.2207 · Cited by 215 · see citing works

A RAP1/TRF2 Complex Inhibits Nonhomologous End-Joining at Human Telomeric DNA Ends

Bae, N. S., & Baumann, P. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.03.023 · Cited by 215 · see citing works

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination

Robert, I., Dantzer, F., & Reina‐San‐Martin, B. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20082468 · Cited by 203 · see citing works

The Absence of the DNA-Dependent Protein Kinase Catalytic Subunit in Mice Results in Anaphase Bridges and in Increased Telomeric Fusions with Normal Telomere Length and G-Strand Overhang

Goytisolo, F. A., Samper, E., Edmonson, S., Taccioli, G. E., & Blasco, M. A. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.11.3642-3651.2001 · Cited by 199 · see citing works

Multiple functions of MRN in end-joining pathways during isotype class switching

Dinkelmann, M., Spehalski, E. I., Stoneham, T., Buis, J. M., Wu, Y., Sekiguchi, J., & Ferguson, D. O. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1639 · Cited by 197 · see citing works

Multiple roles for MRE11 at uncapped telomeres

Deng, Y., Guo, X., Ferguson, D. O., & Chang, S. S. (2009) · Nature · doi:10.1038/nature08196 · Cited by 194 · see citing works

A Backup DNA Repair Pathway Moves to the Forefront

Nussenzweig, A., & Nussenzweig, M. C. (2007) · Cell · doi:10.1016/j.cell.2007.10.005 · Cited by 191 · see citing works

A topological mechanism for TRF2-enhanced strand invasion

Amiard, S., Doudeau, M., Pinte, S., Poulet, A., Lenain, C., Faivre-Moskalenko, C., Angelov, D., Hug, N., Vindigni, A., Bouvet, P., et al. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1192 · Cited by 189 · see citing works

DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity

Modesti, M., Hesse, J. E., & Gellert, M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.7.2008 · Cited by 183 · see citing works

Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends

Guirouilh‐Barbat, J., Rass, E., Plo, I., Bertrand, P., & López, B. S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708541104 · Cited by 180 · see citing works

DNA-PKcs is critical for telomere capping

Gilley, D. P., Tanaka, H., Hande, M. P., Kurimasa, A., Li, G. C., Oshimura, M., & Chen, D. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.261574698 · Cited by 177 · see citing works

Interaction of human Ku70 with TRF2

Song, K. B., Jung, D., Jung, Y., Lee, S. G., & Lee, I. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01958-x · Cited by 177 · see citing works

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

Liang, L., Deng, L., Nguyen, S. C., Zhao, X., Maulion, C., Shao, C., & Tischfield, J. A. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn184 · Cited by 158 · see citing works

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair

Adachi, N., Ishino, T., Ishii, Y., Takeda, S., & Koyama, H. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.201271098 · Cited by 155 · see citing works

DNA-dependent Protein Kinase and XRCC4-DNA Ligase IV Mobilization in the Cell in Response to DNA Double Strand Breaks

Drouet, J., Delteil, C., Lefrançois, J., CONCANNON, P. J., Salles, B., & Calsou, P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410746200 · Cited by 154 · see citing works

Ku: A multifunctional protein involved in telomere maintenance

Fisher, T. S., & Zakian, V. A. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.04.021 · Cited by 152 · see citing works

Deletion of Ku70, Ku80, or Both Causes Early Aging without Substantially Increased Cancer

Li, H., Vogel, H. S., Holcomb, V. B., Gu, Y., & Hasty, P. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00785-07 · Cited by 151 · see citing works

Human RAP1 inhibits non‐homologous end joining at telomeres

Sarthy, J., Bae, N. S., Scrafford, J., & Baumann, P. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.275 · Cited by 151 · see citing works

Functional interaction between DNA‐PKcs and telomerase in telomere length maintenance

Espejel, S., Franco, S., Sgura, A., Gae, D., Bailey, S. M., Taccioli, G. E., & Blasco, M. A. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf593 · Cited by 128 · see citing works

Backup pathways of NHEJ are suppressed by DNA‐PK

Perrault, A. R., Wang, H., Wang, M., Rosidi, B., & Iliakis, G. E. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20104 · Cited by 127 · see citing works

PARP1 Is a TRF2-associated Poly(ADP-Ribose)Polymerase and Protects Eroded Telomeres

Gomez, M., Wu, J., Schreiber, V., Dunlap, J. R., Dantzer, F., Wang, Y., & Liu, Y. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-07-0672 · Cited by 125 · see citing works

Human Cancer Cells Harbor T-Stumps, a Distinct Class of Extremely Short Telomeres

Xu, L., & Blackburn, E. H. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.10.005 · Cited by 121 · see citing works

Telomere uncapping and alternative lengthening of telomeres

Cesare, A. J., & Reddel, R. R. (2007) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2007.11.006 · Cited by 119 · see citing works

The Role of the Nonhomologous End-Joining DNA Double-Strand Break Repair Pathway in Telomere Biology

Říha, K., Heacock, M. L., & Shippen, D. E. (2006) · Annual Review of Genetics · doi:10.1146/annurev.genet.39.110304.095755 · Cited by 118 · see citing works

Length-dependent Binding of Human XLF to DNA and Stimulation of XRCC4·DNA Ligase IV Activity

Lu, H., Pannicke, U., Schwarz, K., & Lieber, M. R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m609904200 · Cited by 110 · see citing works

Activation of DNA-dependent Protein Kinase by Single-stranded DNA Ends

Hammarsten, O., DeFazio, L. G., & Chu, G. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.3.1541 · Cited by 109 · see citing works

Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells

Wang, H. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.8.1653 · Cited by 109 · see citing works

The DNA-dependent Protein Kinase Catalytic Activity Regulates DNA End Processing by Means of Ku Entry into DNA

Calsou, P., Frit, P., Humbert, O., Muller, C., Chen, D. J., & Salles, B. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.12.7848 · Cited by 108 · see citing works

The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants

Karanjawala, Z. E., Adachi, N., Irvine, R. A., Oh, E. K., Shibata, D. K., Schwarz, K., Hsieh, C., & Lieber, M. R. (2002) · DNA repair · doi:10.1016/s1568-7864(02)00151-9 · Cited by 98 · see citing works

Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2Preprint

Konishi, A., & de Lange, T. (2008) · Genes & Development · doi:10.1101/gad.1634008 · Cited by 98 · see citing works

Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs

Espejel, S., Klatt, P., Murcia, J. M., Martín‐Caballero, J., Flores, J. M., Taccioli, G. E., de MURCIA, G., & Blasco, M. A. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200407178 · Cited by 88 · see citing works

Chromosome Fusions following Telomere Loss Are Mediated by Single-Strand Annealing

Wang, X., & Baumann, P. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.05.028 · Cited by 84 · see citing works

The kinase activity of DNA-PK is required to protect mammalian telomeres

Bailey, S. M., Brenneman, M. A., Halbrook, J., Nickoloff, J. A., Ullrich, R. L., & Goodwin, E. H. (2003) · DNA repair · doi:10.1016/j.dnarep.2003.10.013 · Cited by 83 · see citing works

Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks

Schulte‐Uentrop, L., El‐Awady, R., Schliecker, L., Willers, H., & Dahm‐Daphi, J. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn094 · Cited by 79 · see citing works

DNA-Dependent Protein Kinase Catalytic Subunit Is Not Required for Dysfunctional Telomere Fusion and Checkpoint Response in the Telomerase-Deficient Mouse

Maser, R. S., Wong, K., Sahin, E., Xia, H., Naylor, M. L., Hedberg, H. M., Artandi, S. E., & DePinho, R. A. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.01354-06 · Cited by 79 · see citing works

Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence

Williams, E. S., Klingler, R., Ponnaiya, B., Hardt, T., Schröck, E., Lees‐Miller, S. P., Meek, K., Ullrich, R. L., & Bailey, S. M. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2854 · Cited by 73 · see citing works

Exonuclease Function of Human Mre11 Promotes Deletional Nonhomologous End Joining

Zhuang, J., Jiang, G., Willers, H., & Xia, F. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.059444 · Cited by 68 · see citing works

Interplay between Cernunnos-XLF and Nonhomologous End-joining Proteins at DNA Ends in the Cell

Wu, P.-Y., Frit, P., Malivert, L., Revy, P., Biard, D. S. F., Salles, B., & Calsou, P. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704554200 · Cited by 66 · see citing works

Alternative endings

Haber, J. E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711334105 · Cited by 59 · see citing works

Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ

Hsiao, S. J., & Smith, S. H. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200810132 · Cited by 51 · see citing works

Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis

Jovanović, M. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkj504 · Cited by 39 · see citing works

Protection of DNA Ends by Telomeric 3′ G-Tail Sequences

Tsai, Y.-C., Qi, H., & Liu, L. F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702171200 · Cited by 24 · see citing works

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

Fumagalli, M., Rossiello, F., Clerici, M., Barozzi, S., Cittaro, D., Kaplunov, J. M., Bucci, G., Dobreva, M., Matti, V., Beausejour, C. M., et al. (2012) · Nature Cell Biology · doi:10.1038/ncb2466 · Cited by 851 · see citing works

Telomeres and cell senescence—size matters not

Victorelli, S., & Passos, J. F. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.03.027 · Cited by 413 · see citing works

Plant flavonoids in cancer chemoprevention: role in genome stability

Vazhappilly, C. G., Dellaire, G., & Rupasinghe, H. P. V. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.11.007 · Cited by 363 · see citing works

A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells

Gómez, D., Guédin, A., Mergny, J., Salles, B., Riou, J., Teulade‐Fichou, M., & Calsou, P. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq563 · Cited by 187 · see citing works

Alternative end-joining pathway(s): Bricolage at DNA breaks

Frit, P., Barboule, N., Yuan, Y., Gómez, D., & Calsou, P. (2014) · DNA repair · doi:10.1016/j.dnarep.2014.02.007 · Cited by 166 · see citing works

Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing

Rossiello, F., Herbig, U., Longhese, M. P., Fumagalli, M., & di Fagagna, F. D. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2014.06.009 · Cited by 156 · see citing works

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks

Cheng, Q., Barboule, N., Frit, P., Gómez, D., Bombarde, O., Couderc, B. C., Ren, G.-S., Salles, B., & Calsou, P. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr656 · Cited by 125 · see citing works

A noncatalytic function of the ligation complex during nonhomologous end joining

Jessica, C., Frit, P., Bombarde, O., Salles, B., Négrel, A., Bernard, S., Jeggo, P. A., Lieber, M. R., Modesti, M., & Calsou, P. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201203128 · Cited by 105 · see citing works

The Multifaceted Roles of Ku70/80

Zahid, S., Dahan, M. S. E., Iehl, F., Varela, P. F., Du, M. L., Ropars, V., & Charbonnier, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084134 · Cited by 101 · see citing works

Oxidative Stress-Induced Cellular Senescence: Is Labile Iron the Connecting Link?

Nousis, L., Kanavaros, P., & Barbouti, A. (2023) · Antioxidants · doi:10.3390/antiox12061250 · Cited by 96 · see citing works

Chromatin Structure in Telomere Dynamics

Galati, A., Micheli, E., & Cacchione, S. (2013) · Frontiers in Oncology · doi:10.3389/fonc.2013.00046 · Cited by 89 · see citing works

Chromosome end protection by blunt-ended telomeresPreprint

Kazda, A., Zellinger, B., Rössler, M., Derboven, E., Kusenda, B., & Říha, K. (2012) · Genes & Development · doi:10.1101/gad.194944.112 · Cited by 80 · see citing works

Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer

Dueva, R., & Iliakis, G. E. (2013) · Translational Cancer Research · doi:10.21037/1152 · Cited by 82 · see citing works

Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs

Dregalla, R. C., Zhou, J., Idate, R., Battaglia, C. L. R., Liber, H. L., & Bailey, S. M. (2010) · Aging · doi:10.18632/aging.100210 · Cited by 78 · see citing works

TRF2 Interaction with Ku Heterotetramerization Interface Gives Insight into c-NHEJ Prevention at Human Telomeres

Ribes‐Zamora, A., Indiviglio, S. M., Mihalek, I., Williams, C. L., & Bertuch, A. A. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.08.040 · Cited by 74 · see citing works

Human RAP1 specifically protects telomeres of senescent cells from DNA damage

Lototska, L., Yue, J., Li, J., Giraud-Panis, M.-J. E., Songyang, Z., Royle, N. J., Liti, G., Ye, J., Gilson, É., & Méndez-Bermúdez, A. (2020) · EMBO Reports · doi:10.15252/embr.201949076 · Cited by 74 · see citing works

Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis

Shim, G., Ricoul, M., Hempel, W. M., Azzam, E. I., & Sabatier, L. (2014) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2014.01.001 · Cited by 64 · see citing works

Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis

Sishc, B. J., Nelson, C. B., McKenna, M. J., Battaglia, C. L. R., Herndon, A. K., Idate, R., Liber, H. L., & Bailey, S. M. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00257 · Cited by 62 · see citing works

Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy

Khattar, E., Maung, K. Z. Y., Chew, C. L., Ghosh, A., Mok, M. M. H., Lee, P., Zhang, J., Chor, W. H. J., Cildir, G., Wang, C. Q., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13082-9 · Cited by 61 · see citing works

Similarities and differences between “uncapped” telomeres and DNA double-strand breaks

Dewar, J. M., & Lydall, D. A. (2011) · Chromosoma · doi:10.1007/s00412-011-0357-2 · Cited by 62 · see citing works

Human Rap1 Interacts Directly with Telomeric DNA and Regulates TRF2 Localization at the Telomere

Arat, N. Ö., & Griffith, J. D. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.415984 · Cited by 60 · see citing works

Structural identity of telomeric complexes

Giraud-Panis, M.-J. E., Pisano, S., Poulet, A., Du, M. L., & Gilson, É. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.08.004 · Cited by 54 · see citing works

No DDRama at chromosome ends: TRF2 takes centre stage

Feuerhahn, S., Chen, L., Luke, B., & Porro, A. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.03.003 · Cited by 52 · see citing works

The SUN1-SPDYA interaction plays an essential role in meiosis prophase I

Chen, Y., Wang, Y., Chen, J., Zuo, W., Fan, Y., Huang, S., Liu, Y., Chen, G., Li, Q., Li, J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23550-w · Cited by 48 · see citing works

Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas

Martínez‐A, C., & van Wely, K. H. M. (2011) · Carcinogenesis · doi:10.1093/carcin/bgr069 · Cited by 46 · see citing works

Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction

Oh, S., Wang, Y., Zimbric, J., & Hendrickson, E. A. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1326 · Cited by 46 · see citing works

Potential of Naturally Derived Compounds in Telomerase and Telomere Modulation in Skin Senescence and Aging

Jacczak, B., Rubiś, B., & Totoń, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126381 · Cited by 41 · see citing works

Radiation-induced unrepairable DSBs: their role in the late effects of radiation and possible applications to biodosimetry

Noda, A. (2017) · Journal of Radiation Research · doi:10.1093/jrr/rrx074 · Cited by 41 · see citing works

DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres

Myler, L. R., Toia, B., Vaughan, C. K., Takai, K., Matei, A. M., Wu, P. V., Paull, T. T., de Lange, T., & Lottersberger, F. (2023) · Nature Structural & Molecular Biology · doi:10.1038/s41594-023-01072-x · Cited by 40 · see citing works

DNA–dependent protein kinase in telomere maintenance and protection

Sui, J.-D., Zhang, S., & Chen, B. P. C. (2020) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-020-0199-0 · Cited by 38 · see citing works

A novel cytoprotective function for the DNA repair protein Ku in regulating p53 mRNA translation and function

Lamaa, A., Bras, M. L., Skuli, N., Britton, S., Frit, P., Calsou, P., Prats, H., Cammas, A., & Millevoi, S. (2016) · EMBO Reports · doi:10.15252/embr.201541181 · Cited by 34 · see citing works

Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells

Li, B., Reddy, S., & Comai, L. (2011) · Aging · doi:10.18632/aging.100308 · Cited by 33 · see citing works

Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition

Ghilain, C., Gilson, É., & Giraud-Panis, M.-J. E. (2021) · Cells · doi:10.3390/cells10071753 · Cited by 33 · see citing works

Protection of Arabidopsis Blunt-Ended Telomeres Is Mediated by a Physical Association with the Ku Heterodimer

Valuchova, S. B., Fulneček, J., Prokop, Z., Stolt-Bergner, P. C., Janoušková, E., Hofr, C., & Říha, K. (2017) · The Plant Cell · doi:10.1105/tpc.17.00064 · Cited by 33 · see citing works

Taking apart Rap1

Kabir, S., Sfeir, A. J., & de Lange, T. (2010) · Cell Cycle · doi:10.4161/cc.9.20.13579 · Cited by 32 · see citing works

Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cells

Pennarun, G., Picotto, J., Etourneaud, L., Redavid, A. R., Certain, A., Gauthier, L., Fontanilla-Ramirez, P., Busso, D., Chabance-Okumura, C., Thezé, B., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab761 · Cited by 33 · see citing works

Telomeres: beacons of autocrine and paracrine DNA damage during skin aging

Victorelli, S. G., & Passos, J. F. (2020) · Cell Cycle · doi:10.1080/15384101.2020.1728016 · Cited by 32 · see citing works

Arsenic exposure, genetic susceptibility and leukocyte telomere length in an Italian young adult population

Borghini, A., Faìta, F., Mercuri, A., Minichilli, F., Bustaffa, E., Bianchi, F., & Andreassi, M. G. (2016) · Mutagenesis · doi:10.1093/mutage/gew017 · Cited by 30 · see citing works

Coordinate regulation between expression levels of telomere‐binding proteins and telomere length in breast carcinomas

Butler, K. S., Hines, W. C., Heaphy, C. M., & Griffith, J. K. (2012) · Cancer Medicine · doi:10.1002/cam4.14 · Cited by 28 · see citing works

Design of High-Affinity Stapled Peptides To Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-Binding Factor 2 (TRF2) Protein–Protein Interaction in the Shelterin Complex

Xu, R., Liu, L., Yang, C., Lu, J., Chen, Y., Lei, M., & Wang, S. (2015) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01465 · Cited by 25 · see citing works

Unraveling secrets of telomeres: One molecule at a time

Lin, J., Kaur, P., Countryman, P. J., Opresko, P. L., & Wang, H. (2014) · DNA repair · doi:10.1016/j.dnarep.2014.01.012 · Cited by 24 · see citing works

Recruitment of TRF2 to laser-induced DNA damage sites

Huda, N., Abe, S., Gu, L., Mendonca, M. S., Mohanty, S. K., & Gilley, D. P. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.07.024 · Cited by 23 · see citing works

Trypanosoma brucei RAP1 Has Essential Functional Domains That Are Required for Different Protein Interactions

Afrin, M., Kishmiri, H., Sandhu, R. S., Rabbani, M. A. G., & Li, B. (2020) · mSphere · doi:10.1128/msphere.00027-20 · Cited by 21 · see citing works

TRF1 and TRF2 Differentially Modulate Rad51-Mediated Telomeric and Nontelomeric Displacement Loop Formation in Vitro

Bower, B. D., & Griffith, J. D. (2014) · Biochemistry · doi:10.1021/bi5006249 · Cited by 21 · see citing works

Spontaneous tumor development in bone marrow-rescued DNA-PKcs3A/3A mice due to dysfunction of telomere leading strand deprotection

Zhang, S., Matsunaga, S., Lin, Y., Sishc, B. J., Shang, Z., Sui, J.-D., Shih, H.-Y., Zhao, Y. B., Foreman, O., Story, M. D., et al. (2015) · Oncogene · doi:10.1038/onc.2015.459 · Cited by 20 · see citing works

The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage Response

Imran, S. A. M., Yazid, M. D., Cui, W., & Lokanathan, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189900 · Cited by 18 · see citing works

DNA-PK controls Apollo’s access to leading-end telomeres

Sönmez, C., Toia, B., Eickhoff, P., Matei, A. M., Beyrouthy, M. E., Wallner, B., Douglas, M. E., de Lange, T., & Lottersberger, F. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae105 · Cited by 20 · see citing works

Knockdown of telomeric repeat binding factor 2 enhances tumor radiosensitivity regardless of telomerase status

Yang, X., Li, Z., Yang, L., Han, L., Yu, H., Liao, Z., Zhou, F., Xie, C., & Zhou, Y. (2015) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-015-1911-8 · Cited by 19 · see citing works

Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein

Yuan, Y., Britton, S., Delteil, C., Coates, J., Jackson, S. P., Barboule, N., Frit, P., & Calsou, P. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv894 · Cited by 17 · see citing works

Telomere maintenance in interplay with DNA repair in pathogenesis and treatment of colorectal cancer

Tomášová, K., Kroupa, M., Försti, A., Vodička, P., & Vodičková, Ľ. (2020) · Mutagenesis · doi:10.1093/mutage/geaa005 · Cited by 17 · see citing works

Close Ties between the Nuclear Envelope and Mammalian Telomeres: Give Me Shelter

Pennarun, G., Picotto, J., & Bertrand, P. (2023) · Genes · doi:10.3390/genes14040775 · Cited by 16 · see citing works

Murine Prkdc polymorphisms impact DNA-PKcs function

Fabre, K. M., Ramaiah, L., Dregalla, R. C., Desaintes, C., Weil, M. M., Bailey, S. M., & Ullrich, R. L. (2011) · Radiation Research · doi:10.1667/rr2431.1 · Cited by 13 · see citing works

Telomere Crisis Shapes Cancer EvolutionPreprint

Nassour, J., & Karlseder, J. (2025) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041688 · Cited by 13 · see citing works

Chromosome end protection by RAP1-mediated inhibition of DNA-PK

Eickhoff, P., Sönmez, C., Fisher, C. E. L., Inian, O., Roumeliotis, T. I., Stritto, A. D., Mansfeld, J., Choudhary, J. S., Guettler, S., Lottersberger, F., et al. (2025) · Nature · doi:10.1038/s41586-025-08896-1 · Cited by 9 · see citing works

Canonical and non-canonical functions of the non-coding RNA component (TERC) of telomerase complex

Cao, C., Gong, W., Shuai, Y., Rasouli, S., Ge, Q., Anam Qadir, K. H. A. N., Dakic, A., Putluri, N., Shvets, G. B., Zheng, Y., et al. (2025) · Cell & Bioscience · doi:10.1186/s13578-025-01367-0 · Cited by 7 · see citing works

Telomeric Double Strand Breaks in G1 Human Cells Facilitate Formation of 5′ C-Rich Overhangs and Recruitment of TERRA

Nelson, C. B., Al-Turki, T. M., Luxton, J. J., Taylor, L. E., Maranon, D. G., Muraki, K., Murnane, J. P., & Bailey, S. M. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.644803 · Cited by 8 · see citing works

Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer

Ng, Y. B., & Akıncılar, S. C. (2024) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2024.102460 · Cited by 6 · see citing works

Different DNA-PKcs functions in the repair of radiation-induced and spontaneous DSBs within interstitial telomeric sequences

Revaud, D., Martins, L. M., Boussin, F. D., Sabatier, L., & Desmaze, C. (2011) · Chromosoma · doi:10.1007/s00412-011-0313-1 · Cited by 6 · see citing works

The telomere protein tankyrase 1 regulates DNA damage responses at telomeres

Chang, S. S. (2010) · Aging · doi:10.18632/aging.100221 · Cited by 6 · see citing works

Restriction of Ku translocation protects telomere ends

Mattarocci, S., Baconnais, S., Roisné-Hamelin, F., Pobiega, S., Alibert, O., Morin, V., Deshayes, A., Veaute, X., Ropars, V., Chevreuil, M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-61864-1 · Cited by 5 · see citing works

Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins

Lustig, A. J. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00010 · Cited by 5 · see citing works

DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeresPreprint

Myler, L. R., Toia, B., Vaughan, C. K., Takai, K., Matei, A. M., Wu, P. V., Paull, T. T., de Lange, T., & Lottersberger, F. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.06.531339 · Cited by 5 · see citing works

Aging and Protein Kinases

Engin, A. B., & Engin, A. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-49844-3_2 · Cited by 4 · see citing works

DNA-PK, a Pharmacological Target in Cancer Chemotherapy and Radiotherapy?

Salles, B., Calsou, P., & Mirey, G. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4741-2_2 · Cited by 4 · see citing works

Restriction on Ku’s Inward Translocation Caps Telomere EndsPreprint

Mattarocci, S., Baconnais, S., Roisné-Hamelin, F., Pobiega, S., Alibert, O., Morin, V., Deshayes, A., Veaute, X., Ropars, V., Chevreuil, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.22.629684 · Cited by 3 · see citing works

Phage-encoded TelN inhibits bacterial Mre11-Rad50 nuclease to protect hairpin telomeres

Houmel, M., Pellaton, N., Anchimiuk, A., & Gruber, S. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00593-z · Cited by 2 · see citing works

Extra-Telomeric Roles of Telomeric Proteins

Ghosh, A., & Tergaonkar, V. (2012) · InTech eBooks · doi:10.5772/38661 · Cited by 2 · see citing works

Tetrameric TRF2 forms t-loop to protect telomeres from ATM signaling and cNHEJPreprint

Goldfarb, A. M., Sasi, N. K., Dilgen, T. C., Cai, S. W., Myler, L. R., & de Lange, T. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.27.600884 · Cited by 2 · see citing works

The blood toll of arsenic: addressing hematological disorders and future directions

Mondal, R., Mishra, R., Maity, J., Chanda, P., Das, S., Dey, M., Ghoshal, S., Ghosh, T. K., & Mukhopadhyay, P. K. (2026) · International Journal of Community Medicine and Public Health · doi:10.18203/2394-6040.ijcmph20260721 · Cited by 1 · see citing works

Telomeres Shortening: A Mere Replicometer?

Victorelli, S. G., & Passos, J. F. (2016) · Healthy ageing and longevity · doi:10.1007/978-3-319-26239-0_7 · Cited by 1 · see citing works

DNA-PK, a Pharmacological Target in Cancer Chemotherapy and Radiotherapy?

Salles, B. (2012) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s8-001 · Cited by 1 · see citing works

DNA-PK, a Pharmacological Target in Cancer Chemotherapy and

Salles, R., Calsou, P., & Mirey, G. (2011)

End-synapsis Assay

Jessica, C., & Calsou, P. (2013) · BIO-PROTOCOL · doi:10.21769/bioprotoc.900

Development of metal complexes and affinity tags that interact selectively with G-quadruplex nucleic acids

Stafford, V. S. (2014) · doi:10.25560/42996

The role of melanocyte senescence in skin ageing

Victorelli, S. G. (2018)

Telomere Binding Protein Antagonists for Stem Cell Therapy

VanGarde, A. (2011)

Basic Research

Maru, Y. (2016) · Springer eBooks · doi:10.1007/978-4-431-56024-1_10

Basic Research

Maru, Y. (2021) · Springer eBooks · doi:10.1007/978-981-16-1757-7_10

Telomeres and cell homeostasis in aging

Victorelli, S. G., & Passos, J. F. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823761-8.00029-x

The Shelterin Complex

Ghilain, C., Gilson, É., & Giraud-Panis, M.-J. E. (2024) · Wiley eBooks · doi:10.1002/9781394300808.ch3

Rôle de la protéine télomérique TRF1 sur la stabilité chromosomique et la longévité des cellules normales humaines

Jullien, L. (2010) · doi:10.70675/ea62b7adza902z4c9fz9737z7cc2e070f327

Rôle des protéines de liaison à l'ARN hnRNP H et hnRNP F dans les régulations traductionnelles dans les glioblastomes

Bras, M. L. (2018) · doi:10.70675/d2b8fba3zf615z493ezbc49z10c85cf135c7

Interaction between telomeres and the nuclear envelope in human cells : dynamics and molecular mechanism

Kychygina, G. (2019) · doi:10.70675/257216a4zfec4z40ccza35bz81fab5ab7e1e

Investigation into the role of human RAP1 in telomere protection

Lototska, L. (2018) · theses.fr (ABES) · doi:10.70675/206c00d7zf1c8z46bcz8d20zb2289991e250

"Rôle du complexe Stn1-Ten1 et de la télomérase dans le contrôle du stress réplicatif aux télomères chez la levure Schizosaccharomyces pombe"

Matmati, S. (2019) · theses.fr (ABES) · doi:10.70675/fadbf506z1c0fz43aeza97bz78a486b3638b

Étude structurale du complexe formé par la protéine Werner (WRN) et l'hétérodimère Ku70/80

Zahid, S. (2022) · doi:10.70675/b9f0dba1z1963z4f82zab5dz0b4c5c276c7e

Implications de la lamine B1 dans la stabilité des télomères et la mitose

Picotto, J. (2024) · theses.fr (ABES) · doi:10.70675/8a35d253z2bc1z4f60za910za75252660ead

Chromatin signaling in aging and cellular senescence

Gagné, L. M., Couteau, F., & Mallette, F. A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-19001-8.00018-0

Taming Mre11–Rad50 at Telomeres: Convergent Strategies for Chromosome‐End Protection Across Evolution

Roisné-Hamelin, F., & Gruber, S. (2026) · BioEssays · doi:10.1002/bies.70197

BindingDB Entry 50046901: Design of High-Affinity Stapled Peptides To Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-Binding Factor 2 (TRF2) Protein-Protein Interaction in the Shelterin Complex.

BindingDB (2017) · UC San Diego · doi:10.7270/q2mp553d

Chromosome end protection by RAP1-mediated inhibition of DNA-PK

Eickhoff, P., Sönmez, C., Fisher, C. E. L., Inian, O., Roumeliotis, T. I., Stritto, A. D., Mansfeld, J., Choudhary, J. S., Guettler, S., Lottersberger, F., et al. (2025) · Nature · doi:10.1038/s41586-025-08896-1 · Cited by 9 · see citing works

The kinase activity of DNA-PK is required to protect mammalian telomeres

Bailey, S. M., Brenneman, M. A., Halbrook, J., Nickoloff, J. A., Ullrich, R. L., & Goodwin, E. H. (2003) · DNA repair · doi:10.1016/j.dnarep.2003.10.013 · Cited by 83 · see citing works

DNA–dependent protein kinase in telomere maintenance and protection

Sui, J.-D., Zhang, S., & Chen, B. P. C. (2020) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-020-0199-0 · Cited by 38 · see citing works

A RAP1/TRF2 Complex Inhibits Nonhomologous End-Joining at Human Telomeric DNA Ends

Bae, N. S., & Baumann, P. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.03.023 · Cited by 215 · see citing works

Restriction of Ku translocation protects telomere ends

Mattarocci, S., Baconnais, S., Roisné-Hamelin, F., Pobiega, S., Alibert, O., Morin, V., Deshayes, A., Veaute, X., Ropars, V., Chevreuil, M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-61864-1 · Cited by 5 · see citing works