The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Metabolic pathways promoting cancer cell survival and growth
Open accessAbstract
Activation of oncogenes and loss of tumour suppressors promote metabolic reprogramming in cancer, resulting in enhanced nutrient uptake to supply energetic and biosynthetic pathways. However, nutrient limitations within solid tumours may require that malignant cells exhibit metabolic flexibility to sustain growth and survival. Here, we highlight these adaptive mechanisms and also discuss emerging approaches to probe tumour metabolism in vivo and their potential to expand the metabolic repertoire of malignant cells even further.
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Cites
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Cited by
The Warburg Effect: How Does it Benefit Cancer Cells?
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Self-citationCancer metabolism: a therapeutic perspective
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The cancer metabolic reprogramming and immune response
Xia, L., Oyang, L., Lin, J., Tan, S., Han, Y., Wu, N., Yi, P., Tang, L., Pan, Q., Rao, S., et al. (2021) · Molecular Cancer · doi:10.1186/s12943-021-01316-8 · Cited by 1,312
Acetyl coenzyme A: a central metabolite and second messenger
Pietrocola, F., Galluzzi, L., Bravo-San Pedro, J. M., Madeo, F., & Kroemer, G. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.05.014 · Cited by 1,378
Metadata
- Authors
- Boroughs, L. K., & DeBerardinis, R. J.
- Venue
- Nature Cell Biology
- Published
- 2015-03-16
- Volume
- 17
- Issue
- 4
- Pages
- 351-359
- ISSN
- 1465-7392 (ISSN-L)
- 1476-4679
- OpenAlex
- W2070923004
- Cited by
- 1,462
- References
- 49
- FWCI
- 33.27
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
