Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

Elosegui-Artola, Alberto, Oria, Roger, Chen, Yunfeng, Kosmalska, Anita, Pérez-González, Carlos, Castro, Natalia, Zhu, Cheng, Trepat, Xavier +1 more·2016·Nature Cell Biology

DOI 10.1038/ncb3336

Cited by (862)

Items 401–500 of 862

Multiscale models of integrins and cellular adhesions
Tamara C. Bidone, David J. Odde · 2023 · Current Opinion in Structural Biology
A multi-scale clutch model for adhesion complex mechanics
Chiara Venturini, Pablo Sáez · 2023 · PLoS Computational Biology
Harnessing mechanobiology for kidney organoid research
Zarina Nauryzgaliyeva, Iphigénie Goux Corredera, Elena Garreta, Núria Montserrat · 2023 · Frontiers in Cell and Developmental Biology
Epithelial Cell Mechanoresponse to Matrix Viscoelasticity and Confinement Within Micropatterned Viscoelastic Hydrogels
Giuseppe Ciccone, Mariana Azevedo Gonzalez‐Oliva, Marie Versaevel, Marco Cantini, Massimo Vassalli, Manuel Salmerón‐Sánchez, Sylvain Gabriele · 2025 · Advanced Science
Mechanical Regulation of Epithelial Tissue Homeostasis
Sara Kaliman, Maxime Hubert, Carina Wollnik, Lovro Nuić, Damir Vurnek, Simone Gehrer, Jakov Lovrić, Diana Dudziak, Florian Rehfeldt, Ana‐Sunčana Smith · 2021 · Physical Review X
α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence
Abhishek Mukherjee, Shay Melamed, Hana Damouny-Khoury, Malak Amer, Lea Feld, Elisabeth Nadjar-Boger, Michael P. Sheetz, Haguy Wolfenson · 2022 · The Journal of Cell Biology
Neuronal Cells Confinement by Micropatterned Cluster-Assembled Dots with Mechanotransductive Nanotopography
Carsten Schulte, Jacopo Lamanna, Andrea Stefano Moro, Claudio Piazzoni, Francesca Borghi, Matteo Chighizola, Serena Ortoleva, Gabriella Racchetti, Cristina Lenardi, Alessandro Podestà et al. · 2018 · ACS Biomaterials Science & Engineering
Negative durotaxis: cell movement toward softer environments
Aleksi Isomursu, Keun‐Young Park, Jay Hou, Bo Cheng, Ghaidan A. Shamsan, Benjamin Fuller, Jesse Kasim, M. Mohsen Mahmoodi, Tian Jian Lu, Guy M. Genin et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Molecular signaling in biomaterial-induced foreign body response: current perspectives
Suneha G. Rahaman, Mohammad I. Khan, Karunakaran Reddy Sankaran, Shaik O. Rahaman · 2025 · American Journal of Physiology-Cell Physiology
Synthetic mechanotransduction
Miguel González-Martín, Guillermo Martínez-Ara, John T. Ngo, Xavier Trepat, Pere Roca‐Cusachs · 2025 · Nature Reviews Bioengineering
What do cells regulate in soft tissues on short time scales?
Jonas F. Eichinger, Daniel Paukner, Roland Can Aydin, Wolfgang A. Wall, Jay D. Humphrey, Christian Johannes Cyron · 2021 · Acta Biomaterialia
Insights into intercellular receptor-ligand binding kinetics in cell communication
Chenyi An, Xiaohuan Wang, Fan Song, Jinglei Hu, Long Li · 2022 · Frontiers in Bioengineering and Biotechnology
A Yap-dependent mechanoregulatory program sustains cell migration for embryo axis assembly
Ana Sousa‐Ortega, Javier Vázquez-Marín, Estefanía Sanabria‐Reinoso, Jorge Corbacho, Rocío Polvillo, Alejandro Campoy-López, Lorena Buono, Felix Loosli, María Almuedo‐Castillo, Juan Ramón Martínez‐Morales · 2023 · Nature Communications
Native extracellular matrix probes to target patient- and tissue-specific cell–microenvironment interactions by force spectroscopy
Hatice Holuigue, Lucia Nacci, Pierluigi Di Chiaro, Matteo Chighizola, Irene Locatelli, Carsten Schulte, Massimo Alfano, Giuseppe Riccardo Diaferia, Alessandro Podestà · 2023 · Nanoscale
Mechanotransduction through protein stretching
Yanyu Guo, Jie Yan, Benjamin Thomas Goult · 2024 · Current Opinion in Cell Biology
Active viscoelastic models for cell and tissue mechanics
Bahareh Tajvidi Safa, Changjin Huang, Alexandre Kabla, Ruiguo Yang · 2024 · Royal Society Open Science
Creating a bionic scaffold via light-curing liquid crystal ink to reveal the role of osteoid-like microenvironment in osteogenesis
Kun Liu, Lin Li, Yizhi Li, Yiting Luo, Zhaoyu Zhang, Wei Neng Wen, Shan Ding, Yadong Huang, Mingxian Liu, Changren Zhou et al. · 2024 · Bioactive Materials
Lymphocyte mechanotransduction: The regulatory role of cytoskeletal dynamics in signaling cascades and effector functions
Aviad Ben‐Shmuel, Noah Joseph, Batel Sabag, Mira Barda‐Saad · 2019 · Journal of Leukocyte Biology
Intercellular Adhesion Stiffness Moderates Cell Decoupling as a Function of Substrate Stiffness
Diego A. Vargas, Tommy Heck, Bart Smeets, Herman Ramón, Harikrishnan Parameswaran, Hans Van Oosterwyck · 2020 · Biophysical Journal
Mechanics of actin filaments in cancer onset and progress
Mohammad Tafazzoli‐Shadpour, Ehsan Mohammadi, Elham Torkashvand · 2020 · International review of cytology
Manipulation of Axonal Outgrowth via Exogenous Low Forces
Sara De Vincentiis, Alessandro Falconieri, Vincenzo Scribano, Samuele Ghignoli, Vittoria Raffa · 2020 · International Journal of Molecular Sciences
Progress in Integrative Biomaterial Systems to Approach Three-Dimensional Cell Mechanotransduction
Ying Zhang, Kin Liao, Chuan Li, Alvin C.K. Lai, Ji Jinn Foo, Vincent Chan · 2017 · Bioengineering
Yap1b, a divergent Yap/Taz family member, cooperates with yap1 in survival and morphogenesis via common transcriptional targets
Javier Vázquez-Marín, José Arturo Gutierrez-Triana, María Almuedo‐Castillo, Lorena Buono, José Luis Gómez-Skármeta, Juan Luis Mateo, Joachim Wittbrodt, Juan Ramón Martínez‐Morales · 2019 · Development
Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness‐Mediated Bimodal PD‐L1/CXCL10 Regulation
Tian Zhang, Yuan Li, Bo Cheng, Xu Zhao, Mengjie Liu, Jinteng Feng, Yixue Bai, Yang Yu, Panpan Jiang, Luying Geng et al. · 2025 · Advanced Science
Traction force and mechanosensitivity mediate species-specific implantation patterns in human and mouse embryos
Amélie Luise Godeau, Anna Seriola, Oren Tchaicheeyan, Marc Casals, Denitza Denkova, Ester Aroca, Ot Massafret, Albert Parra, Maria Demestre, Anna Ferrer‐Vaquer et al. · 2025 · Science Advances
Epigenetic regulation of mechanotransduction
Ryan S. Stowers, Ovijit Chaudhuri · 2021 · Nature Biomedical Engineering
Sensitive detection of cell-derived force and collagen matrix tension in microtissues undergoing large-scale densification
Xiang Wang, Qiang Gao, Xiaoning Han, Bing Bu, Longfei Wang, Aoqi Li, Linhong Deng · 2021 · Proceedings of the National Academy of Sciences
Metabolic reprogramming in response to cell mechanics
Rebecca L. Splitt, Kris A. DeMali · 2023 · Biology of the Cell
Effects of Elasticity on Cell Proliferation in a Tissue-Engineering Scaffold Pore
Carlyn Annunziata, Haniyeh Fattahpour, Daniel Fong, Michael Hadjiargyrou, Pejman Sanaei · 2023 · Bulletin of Mathematical Biology
Identifying constitutive and context-specific molecular-tension-sensitive protein recruitment within focal adhesions
Arnold Tao, Andrew S. LaCroix, T. Curtis Shoyer, Vidya Venkatraman, Karen L. Xu, Bradley Feiger, Brenton D. Hoffman · 2023 · Developmental Cell
YAP at the Crossroads of Biomechanics and Drug Resistance in Human Cancer
Miao Ling Huang, Heyang Wang, Cole Mackey, Michael C. Chung, Juan Guan, Guangrong Zheng, Arkaprava Roy, Mingyi Xie, Chris D. Vulpe, Xin Tang · 2023 · International Journal of Molecular Sciences
Tunable Double-Network GelMA/Alginate Hydrogels for Platelet Lysate-Derived Protein Delivery
Andrea Marfoglia, Fahd Tibourtine, Ludovic Pilloux, Sophie Cazalbou · 2023 · Bioengineering
TiO 2 Nano‐Biopatterning Reveals Optimal Ligand Presentation for Cell–Matrix Adhesion Formation
Kashish Jain, Ashish Kumar Pandey, Hao Wang, Taerin Chung, Arash Nemati, Pakorn Kanchanawong, Michael P. Sheetz, Haogang Cai, Rishita Changede · 2024 · Advanced Materials
The biochemical composition of the actomyosin network sets the magnitude of cellular traction forces
Somanna A. Kollimada, Fabrice Senger, Timothée Vignaud, Manuel Théry, Laurent Blanchoin, Laëtitia Kurzawa · 2021 · Molecular Biology of the Cell
Integrin molecular tension required for focal adhesion maturation and YAP nuclear translocation
Cheng-Yu Chang Chien, Shih‐Hua Chou, Hsiao‐Hui Lee · 2022 · Biochemistry and Biophysics Reports
Regulation of Substrate Dissipation via Tunable Linear Elasticity Controls Cell Activity
Pasquale Sacco, Francesco Piazza, Chiara Pizzolitto, Gabriele Baj, Francesco Brun, Eleonora Marsich, Ivan Donati · 2022 · Advanced Functional Materials
High expression of Talin-1 is associated with tumor progression and recurrence in melanoma skin cancer patients
Yasaman Rezaie, Fahimeh Fattahi, Baharnaz Mashinchi, Kambiz Kamyab Hesari, Sahar Montazeri, Elham Kalantari, Zahra Madjd, Leili Saeednejad Zanjani · 2023 · BMC Cancer
An amphipathic helix of vinexin α is necessary for a substrate stiffness-dependent conformational change in vinculin
Naoya Hino, Takafumi Ichikawa, Yasuhisa Kimura, Michiyuki Matsuda, Kazumitsu Ueda, Noriyuki Kioka · 2018 · Journal of Cell Science
The bioenergetics of integrin-based adhesion, from single molecule dynamics to stability of macromolecular complexes
Laurent MacKay, Anmar Khadra · 2020 · Computational and Structural Biotechnology Journal
Mechanisms of endothelial stiffening in dyslipidemia and aging: Oxidized lipids and shear stress
Elizabeth Le Master, Sang Joon Ahn, Irena Levitan · 2020 · Current topics in membranes
Catch Bonds in Immunology
Hyun-Kyu Choi, Cheng Zhu · 2025 · Annual Review of Immunology
Vitronectin-based hydrogels recapitulate neuroblastoma growth conditions
Ezequiel Monferrer, Oana Dobre, Sara Trujillo, Mariana Azevedo Gonzalez‐Oliva, Alexandre Trubert-Paneli, Delia Acevedo-León, Rosa Noguera, Manuel Salmerón‐Sánchez · 2022 · Frontiers in Cell and Developmental Biology
Toward Corneal Limbus In Vitro Model: Regulation of hPSC‐LSC Phenotype by Matrix Stiffness and Topography During Cell Differentiation Process
Maija Kauppila, Anni Mörö, Juan José Valle‐Delgado, Teemu O. Ihalainen, Lassi Sukki, Paula Puistola, Pasi J. Kallio, Tanja Ilmarinen, Monika Österberg, Heli Skottman · 2023 · Advanced Healthcare Materials
Enhancement effects of extracellular fluid viscosity and matrix stiffness on cancer cell mechanosensing
Chunyu Cao, Xu Zhao, Yan Liu, Bo Cheng, Feng Xu · 2023 · Acta Mechanica Sinica
Force-dependent focal adhesion assembly and disassembly: A computational study
Kailas Shankar Honasoge, Zeynep Karagöz, Benjamin Thomas Goult, Haguy Wolfenson, Vanessa L.S. LaPointe, Aurélie Carlier · 2023 · PLoS Computational Biology
Environmental stiffness restores mechanical homeostasis in vimentin-depleted cells
Janine Grolleman, Nicole C. A. van Engeland, Minahil Raza, Sepinoud Azimi, Vito Conte, Cecilia Sahlgren, Carlijn V. C. Bouten · 2023 · Scientific Reports
Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration
Seong‐Beom Han, Geonhui Lee, Daesan Kim, Jeong‐Ki Kim, In‐San Kim, Hae‐Won Kim, Dong‐Hwee Kim · 2024 · Advanced Science
Colloidal photonic crystals towards biological applications
Zixin Shu, Xiaoning Sun, Xinyuan Xu, Meng Qin, Jianshu Li · 2024 · Journal of Materials Chemistry B
Competing signaling pathways controls electrotaxis
S. Kulkarni, Francesc Tebar, Carles Rentero, Min Zhao, Pablo Sáez · 2025 · iScience
Mechanical Strain Promotes Proliferation of Adipose-Derived Stem Cells Through the Integrin β1-Mediated RhoA/Myosin Light Chain Pathway
Xihang Chen, Zilong Deng, Yunfan He, Feng Lu, Yi Yuan · 2020 · Tissue Engineering Part A
The mechanical forces that shape our senses
Anh Phuong Le, Jin Kim, Karl R. Koehler · 2022 · Development
Monitoring paxillin in astrocytes reveals the significance of the adhesion G protein coupled receptor VLGR1/ADGRV1 for focal adhesion assembly
Baran E. Güler, Joshua Linnert, Uwe Wolfrum B · 2023 · Basic & Clinical Pharmacology & Toxicology
MCAK-mediated regulation of endothelial cell microtubule dynamics is mechanosensitive to myosin-II contractility
Lauren D’Angelo, Nicole M. Myer, Kenneth A. Myers · 2017 · Molecular Biology of the Cell
Balancing forces in migration
Patrick W. Oakes · 2018 · Current Opinion in Cell Biology
Integration of mechanics and immunology: Perspective for understanding fibrotic disease mechanisms and innovating therapeutic strategies
Lei, Min, Chen, Guobao · 2025 · Acta Biomaterialia
A multiscale whole-cell theory for mechanosensitive migration on viscoelastic substrates
Wenya Shu, C. Nadir Kaplan · 2022 · Biophysical Journal
Soft topographical patterns trigger a stiffness-dependent cellular response to contact guidance
Jordi Comelles, Vanesa Fernández‐Majada, Verónica Acevedo, Beatriz Rebollo-Calderón, Elena Martínez · 2023 · Materials Today Bio
Forces exerted and transduced by cancer‐associated fibroblasts during cancer progression
Madison E. Bates, Sarah Libring, Cynthia A. Reinhart‐King · 2023 · Biology of the Cell
Extracellular matrix sensing via modulation of orientational order of integrins and F-actin in focal adhesions
Valeriia Grudtsyna, Swathi Packirisamy, T. Bidone, Vinay Swaminathan · 2022 · Life Science Alliance
A computational model for early cell spreading, migration, and competing taxis
Joel Betorz, Gaurav R. Bokil, Shreyas M. Deshpande, Shardool Kulkarni, Daniel R. Araya, Chiara Venturini, Pablo Sáez · 2023 · Journal of the Mechanics and Physics of Solids
Reversible Host–Guest Crosslinks in Supramolecular Hydrogels for On‐Demand Mechanical Stimulation of Human Mesenchymal Stem Cells
Philipp Linke, Natalie Munding, Esther Kimmle, Stefan Kaufmann, Kentaro Hayashi, Masaki Nakahata, Yoshinori Takashima, Masaki Sano, Martin Bastmeyer, Thomas W. Holstein et al. · 2023 · Advanced Healthcare Materials
A multiscale dynamic model of cell–substrate interfaces
Huiyan Liang, Wei Ping Fang, Xi‐Qiao Feng · 2024 · Journal of the Mechanics and Physics of Solids
Actin-driven nanotopography promotes stable integrin adhesion formation in developing tissue
Tianchi Chen, Cecilia H. Fernández-Espartero, Abigail Illand, Ching‐Ting Tsai, Yang Yang, Benjamin Klapholz, Pierre Jouchet, Mélanie Fabre, Olivier Rossier, Bianxiao Cui et al. · 2024 · Nature Communications
Platelet-derived growth factor receptor-α and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts
Stephen E. McGowan, Diann M. McCoy · 2017 · American Journal of Physiology-Lung Cellular and Molecular Physiology
Molecular condensation and mechanoregulation of plant class I formin, an integrin‐like actin nucleator
Zhiming Ma, Kexin Zhu, Yong‐Gui Gao, Suet‐Mien Tan, Yansong Miao · 2022 · FEBS Journal
Fibronectin Patches as Anchoring Points for Force Sensing and Transmission in Human Induced Pluripotent Stem Cell-Derived Pericytes
Olga Iendaltseva, Valeria V. Orlova, Christine L. Mummery, Erik H.J. Danen, Thomas Schmidt · 2020 · Stem Cell Reports
Nanomechanical Hallmarks of Helicobacter pylori Infection in Pediatric Patients
Piotr Deptuła, Łukasz Suprewicz, Tamara Daniluk, Andrzej Namiot, Sylwia Joanna Chmielewska, Urszula Daniluk, Dariusz Marek Lebensztejn, Robert Bucki · 2021 · International Journal of Molecular Sciences
Increased intracellular diffusivity of macromolecules within a mammalian cell by low-intensity pulsed ultrasound
Hyo-Jun Kim, Yeonho Choi, So Yeon Kim, Ki Joo Pahk · 2023 · Ultrasonics Sonochemistry
Organelle adaptations in response to mechanical forces during tumour dissemination
Vittoria Graziani, Eva Crosas‐Molist, Samantha L. George, Victoria Sanz‐Moreno · 2024 · Current Opinion in Cell Biology
ZO-1 Regulates Hippo-Independent YAP Activity and Cell Proliferation via a GEF-H1- and TBK1-Regulated Signalling Network
Alexis J. Haas, Mert Karakus, Ceniz Zihni, Maria Susana Balda, Karl Matter · 2024 · Cells
Substrate stiffness-dependent activation of Hippo pathway in cancer associated fibroblasts
Gerard Rubí-Sans, Agata Nyga, Miguel A. Mateos‐Timoneda, Elisabeth Engel · 2024 · Biomaterials Advances
3D Micropatterned Traction Force Microscopy: A Technique to Control 3D Cell Shape While Measuring Cell‐Substrate Force Transmission
Laura M. Faure, Manuel Gómez‐González, Ona Baguer, Jordi Comelles, Elena Martínez, Marino Arroyo, Xavier Trepat, Pere Roca‐Cusachs · 2024 · Advanced Science
Stiff extracellular matrix activates the transcription factor ATF5 to promote the proliferation of cancer cells
Seiichiro Ishihara, Atsushi Enomoto, Akihiro Sakai, Tadashi Iida, Shoichiro Tange, Noriyuki Kioka, Akihiro Nukuda, Ayaka Ichikawa Nagasato, Motoaki Yasuda, Takashi Tokino et al. · 2025 · iScience
Substrate Resistance to Traction Forces Controls Fibroblast Polarization
Dimitris Missirlis, Tamás Haraszti, Lara Heckmann, Joachim Pius Spatz · 2020 · Biophysical Journal
Force-enhanced biophysical connectivity of platelet β3 integrin signaling through Talin is predicted by steered molecular dynamics simulations
Shuixiu Su, Yingchen Ling, Ying Guang Fang, Jianhua Wu · 2022 · Scientific Reports
Extracellular matrix regulates force transduction at VE-cadherin junctions
Xinyu Kong, Adrian Kapustka, Brendan G. Sullivan, Gregory J. Schwarz, Deborah Elaine Leckband · 2022 · Molecular Biology of the Cell
Collagen-Based Biomimetic Systems to Study the Biophysical Tumour Microenvironment
Alessandra Cambi, Maurizio Ventre · 2022 · Cancers
Coupled mechanical mapping and interference contrast microscopy reveal viscoelastic and adhesion hallmarks of monocyte differentiation into macrophages
Mar Eroles, Javier Lopez Alonso, Alexandre Ortega, Thomas Boudier, Khaldoun Gharzeddine, Frank Lafont, Clemens M. Franz, Arnaud Millet, Claire Valotteau, Félix Rico · 2023 · Nanoscale
Building a microfluidic cell culture platform with stiffness control using Loctite 3525 glue
Genaro Vázquez‐Victorio, Cindy Peto‐Gutiérrez, Beatriz Díaz‐Bello, Mariel Cano-Jorge, Daniel Pérez‐Calixto, Alejandra Jiménez-Escobar, Silvia Espinosa‐Matías, Reyna Lara Martínez, Rémi Courson, Laurent Malaquin et al. · 2019 · Lab on a Chip
Platelet-derived Growth Factor-α and Neuropilin-1 Mediate Lung Fibroblast Response to Rigid Collagen Fibers
Stephen E. McGowan, Thiranjeewa I. Lansakara, Diann M. McCoy, Lien Zhu, Alexei V. Tivanski · 2020 · American Journal of Respiratory Cell and Molecular Biology
Materiomechanobiology: bridging material sciences, mechanics and cell biology for advanced therapeutics
Kunyu Zhang, Hongyuan Zhu, Qian Sun, Jiapeng Yang, Guoqing Zhao, Qiang Wei, Min Lin, Yi Cao, Liming Bian · 2025 · Materials Today
Magnesium-containing implants enhance bone healing: A mechanobiological perspective
Zhenkang Wen, Lei Lei, Haozhi Zhang, Zheyu Jin, Zhengming Shan, Weiyang Liu, Wenxue Tong, Jian‐Kun Xu, Ling Qin · 2025 · Mechanobiology in Medicine
Cell Response in Free-Packed Granular Systems
Ana Filipa Cunha, André F. V. Matias, C. S. Dias, Mariana B. Oliveira, N. A. M. Araújo, João Filipe Mano · 2022 · ACS Applied Materials & Interfaces
An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
Lara Toffali, Beatrice D’Ulivo, Cinzia Giagulli, Alessio Montresor, Elena Zenaro, Massimo Delledonne, Marzia Rossato, Barbara Iadarola, Andrea Sbarbati, Paolo Bernardi et al. · 2023 · Cell Reports
The motor-clutch model in mechanobiology and mechanomedicine
Xu Zhao, Feng Xu, Bo Cheng · 2024 · Mechanobiology in Medicine
Superposition of Substrate Deformation Fields Induced by Molecular Clutches Explains Cell Spatial Sensing of Ligands
Ruihao Xue, Yonggang Chen, Ze Gong, Hongyuan Jiang · 2024 · ACS Nano
Vibration-based cell engineering
Olivia Johnson-Love, Manuel Salmerón‐Sánchez, Stuart D. Reid, Peter G. Childs, Matthew John Dalby · 2025 · Nature Reviews Bioengineering
A Review of Talin- and Integrin-Dependent Molecular Mechanisms in Cancer Invasion and Metastasis
Zbigniew Baster, Lindsay Russell, Zenon Rajfur · 2025 · International Journal of Molecular Sciences
Single-cell migration along and against confined haptotactic gradients
Isabela Corina Fortunato, David B. Brückner, Steffen Grosser, Rohit Nautiyal, Leone Rossetti, Miquel Bosch Padrós, Jonel Trebicka, Pere Roca‐Cusachs, Raimon Sunyer, Édouard Hannezo et al. · 2025 · Nature Physics
Cellular and molecular mechanotransduction in bone
Alesha B. Castillo, Julia C. Chen, Christopher Rae Jacobs · 2020 · Elsevier eBooks
Fibronectin anchoring to viscoelastic poly(dimethylsiloxane) elastomers controls fibroblast mechanosensing and directional motility
Dimitris Missirlis, Lara Heckmann, Tamás Haraszti, Joachim Pius Spatz · 2022 · Biomaterials
Cell Activities on Viscoelastic Substrates Show an Elastic Energy Threshold and Correlate with the Linear Elastic Energy Loss in the Strain‐Softening Region
Francesco Piazza, Pasquale Sacco, Eleonora Marsich, Gabriele Baj, Francesco Brun, Fioretta Asaro, Gabriele Grassi, Mario Grassi, Ivan Donati · 2023 · Advanced Functional Materials
Modeling distributed forces within cell adhesions of varying size on continuous substrates
Jay Hou, Ghaidan A. Shamsan, Sarah M. Anderson, Mariah M. McMahon, Liam P. Tyler, Brian T. Castle, Rachel K. Heussner, Paolo P. Provenzano, Daniel F. Keefe, Victor H. Barocas et al. · 2019 · Cytoskeleton
Generic self-stabilization mechanism for biomolecular adhesions under load
Andrea Braeutigam, Ahmet Nihat Şimşek, Gerhard Gompper, Benedikt Sabass · 2022 · Nature Communications
A mathematical analysis of focal adhesion lifetimes and their effect on cell motility
Mary Ellen Rosen, J. C. Dallon · 2022 · Biophysical Journal
Sensing of substratum rigidity and directional migration by fast-crawling cells
Chika Okimura, Yuichi Sakumura, Katsuya Shimabukuro, Yoshiaki Iwadate · 2018 · Physical review. E
A Multiscale Model to Predict Neuronal Cell Deformation with Varying Extracellular Matrix Stiffness and Topography
Mohan Yasodharababu, Arun K. Nair · 2020 · Cellular and Molecular Bioengineering
Talin-vinculin precomplex drives adhesion maturation by accelerated force transmission and vinculin recruitment
Sangyoon J. Han, Evgenia V Azarova, Austin J Whitewood, Alexia Bachir, Edgar Guttierrez, Alex Groisman, Alan Rick Horwitz, Benjamin T Goult, Kevin Dean, Gaudenz M. Danuser · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Development of a Ratiometric Tension Sensor Exclusively Responding to Integrin Tension Magnitude in Live Cells
Anwesha Sarkar, Gopal Niraula, Dana N. LeVine, Yuanchang Zhao, Ying Tu, Keyvan Mollaeian, Juan Ren, Long Que, Xuefeng Wang · 2023 · ACS Sensors
YAP/TAZ cytoskeletal remodelling is driven by mechanotactic and electrotactic cues
Bernadette Basilico, Maddalena Grieco, Stefania D’Amone, Ilaria Elena Palamà, Clotilde Lauro, Pamela Mozetic, Alberto Rainer, Simone De Panfilis, Valeria de Turris, Giuseppe Gigli et al. · 2024 · Materials Advances