Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity
Elosegui-Artola, Alberto, Oria, Roger, Chen, Yunfeng, Kosmalska, Anita, Pérez-González, Carlos, Castro, Natalia, Zhu, Cheng, Trepat, Xavier +1 more·2016·Nature Cell Biology
DOI 10.1038/ncb3336
Cited by (862)
Items 501–600 of 862
- Interaction of integrin αvβ3 and fibronectin under fluid shear forces: implications for tumor cell adhesion and migrationPaimin Zhuo, Quhuan Li, Bishan Yang, Na Li, Zhiqing Luo, Fengxia Zhang · 2025 · Frontiers in Cell and Developmental Biology
- Tuning the matrix: Recent advances in mechanobiology unveiled through polyacrylamide hydrogelsGiuseppe Ciccone, Manuel Salmerón‐Sánchez · 2025 · Current Opinion in Biomedical Engineering
- Mechanotransduction as a therapeutic target for brain tumoursLauren Gomes, Carlos Pardo-Pastor, Jody Rosenblatt, Antonios N. Pouliopoulos · 2025 · EBioMedicine
- The role of non-linear viscoelastic hydrogel mechanics in cell culture and transductionPascal Bertsch, Pasquale Sacco · 2025 · Materials Today Bio
- Magneto-mechanics in mechanobiology: enabling remote force transmission to cells and extracellular matrixDaniel Garcia‐Gonzalez · 2025 · Biophysical Reviews
- Fabrication of cell culture hydrogels by robotic liquid handling automation for high-throughput drug testingEloisa Torchia, Moises Di Sante, Bohdana Horda, Marko Mihajlovic, Julius Zimmermann, Melissa Pezzotti, Elisa Cimetta, Sylvain Gabriele, Ferdinando Auricchio, Johan Ulrik Lind et al. · 2025 · Communications Engineering
- Understanding and Regulating Cell-Matrix Interactions Using Hydrogels of Designable Mechanical PropertiesJiapeng Yang, Yu Zhang, Meng Qin, Wei Cheng, Wei Wang, Yi Cao · 2021 · Journal of Biomedical Nanotechnology
- Mechanosensitive traction force generation is regulated by the neutrophil activation stateHadley A. Witt, Zicheng Yan, David L. Henann, Christian Franck, Jonathan S. Reichner · 2023 · Scientific Reports
- Substrate Stiffness Modulates Stemness and Differentiation of Rabbit Corneal Endothelium Through the Paxillin–YAP PathwayShuting Liu, Hua Chen, Hua-Tao Xie, Xin Liu, Mingchang Zhang · 2024 · Investigative Ophthalmology & Visual Science
- Tuning viscoelasticity and stiffness in bioprinted hydrogels for enhanced 3D cell culture: A multi-scale mechanical analysisSarah Pragnère, Edwin‐Joffrey Courtial, Frédéric Dubreuil, Elisabeth Errazuriz-Cerda, Christophe André Marquette, Emma Petiot, Cyril Pailler-Mattei · 2024 · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
- Corneal Collagen Cross-Linking Pretreatment Mitigates Injury-Induced Inflammation, Hemangiogenesis and Lymphangiogenesis In VivoYirui Zhu, Peter Sol Reinach, Chaoxiang Ge, Yun Li, Biao Wu, Qi Xie, Louis Hak Tien Tong, Wei Chen · 2021 · Translational Vision Science & Technology
- Are Osteoclasts Mechanosensitive Cells?Qingxuan Wang, Mengmeng Duan, Jingfeng Liao, Jing Xie, Chenchen Zhou · 2021 · Journal of Biomedical Nanotechnology
- Microfilament-coordinated adhesion dynamics drives single cell migration and shapes whole tissuesRocío Aguilar-Cuenca, Clara Llorente-González, Carlos Vicente, Miguel Vicente‐Manzanares · 2017 · F1000Research
- Roles of Yes-associated protein and transcriptional coactivator with PDZ-binding motif in non-neoplastic liver diseasesDi Chen, Hongmei Zhang, Xin Zhang, Xia Sun, Qiaohong Qin, Ying Hou, Min Jia, Yulong Chen · 2022 · Biomedicine & Pharmacotherapy
- Exploration of Curvature and Stiffness Dual-Regulated Breast Cancer Cell Motility by a Motor-Clutch Model and Cell Traction Force CharacterizationCong Wang, Xu Zhao, Xingquan Ma, Yuting Yin, Bo Cheng, Yuqing Dong · 2024 · ACS Applied Materials & Interfaces
- Competing elastic and viscous gradients determine directional cell migrationPablo Sáez, Pallavi Uday Shirke, Jyoti R. Seth, Jorge Alegre‐Cebollada, Abhijit Majumder · 2024 · Mathematical Biosciences
- Mechanical induction in metazoan development and evolution: from earliest multi-cellular organisms to modern animal embryosNgoc Dinh Son Nguyen, Emmanuel Farge · 2024 · Nature Communications
- Regulation of cell migration by extracellular matrix mechanics at a glanceCole Allan, Ovijit Chaudhuri · 2025 · Journal of Cell Science
- NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin‐Binding IntegrinsJuan González‐Valdivieso, Giuseppe Ciccone, Udesh Dhawan, Tezz Quon, Eva Barcelona‐Estaje, Aleixandre Rodrigo‐Navarro, Rafael R. Castillo, Graeme Milligan, Patricia Rico, Manuel Salmerón‐Sánchez · 2025 · Advanced Science
- Uncertainty-aware traction force microscopyAdithan Kandasamy, Yi‐Ting Yeh, Ricardo Serrano, Mark A. Mercola, Juan C. del Álamo · 2025 · PLoS Computational Biology
- Mechano-crosstalk between living and artificial cellsXiaolei Yu, Vincent Mukwaya, Li Wang, Weili Zhao, Stephen Mann, Hongjing Dou · 2025 · Nature Communications
- Mechanochemical waves in focal adhesions during cell migrationMarc Fernández, Elijah N. Marquez, Chetan Poojari, Jianping Fu, Yingxiao Wang, Aránzazu del Campo, Andrés J. Garcı́a · 2025 · Science Advances
- Fiber recruitment drives a phase transition of cell polarization at a critical cell spacing in matrix-mediated tissue remodelingXiangjun Peng, Yuxuan Huang, Wenyu Kong, Yanan Du, Elliot L. Elson, Xi‐Qiao Feng, Guy M. Genin · 2025 · Proceedings of the National Academy of Sciences
- Adaptive Cytoskeletal Responses to Extracellular Environment Viscosity Modulate Cell MigrationZhongya Lin, Xindong Chen, Xi-Qiao Feng · 2025 · ACS Nano
- Focus on time: dynamic imaging reveals stretch-dependent cell relaxation and nuclear deformationAron N. Horvath, Andreas A. Ziegler, Stephan Gerhard, Claude N. Holenstein, Benjamin Beyeler, Jess Gerrit Snedeker, Unai Silván · 2021 · Biophysical Journal
- Regulation of the Keratocyte Phenotype and Cell Behavior Derived from Human Induced Pluripotent Stem Cells by Substrate StiffnessLan Zhang, Liying Liang, Ting Su, Yonglong Guo, Quan Yu, Deliang Zhu, Zekai Cui, Jun Zhang, Jiansu Chen · 2023 · ACS Biomaterials Science & Engineering
- High Dynamic Range Probing of Single-Molecule Mechanical Force Transitions at Cell–Matrix Adhesion Bonds by a Plasmonic Tension NanosensorShaojun Wu, Wenjing Tang, Ziyi Wang, Zhuodong Tang, Peng Zheng, Zixuan Chen, Jun‐Jie Zhu · 2024 · JACS Au
- Focal adhesion-mediated directional cell migration guided by gradient-stretched substrateZijia Chen, Xiaoning Han, Bo Che, Huiping Feng, Yue Zhou, Linhong Deng, Xiang Wang · 2024 · iScience
- Spatial regulation of substrate adhesion directs fibroblast morphotype and phenotypeMirko D’Urso, Ignasi Jorba, Atze van der Pol, Carlijn V. C. Bouten, Nicholas A. Kurniawan · 2024 · PNAS Nexus
- Heterogeneous role of integrins in fibroblast response to small cyclic mechanical stimulus generated by a nanoporous gold actuatorSoichiro Deguchi, Atsushi Kato, Peizheng Wu, Masataka Hakamada, Mamoru Mabuchi · 2020 · Acta Biomaterialia
- Mechanotransduction Impairment in Primary Fibroblast Model of Krabbe DiseaseRoberta Mezzena, Ambra Del Grosso, Roberto Maria Pellegrino, Husam B. R. Alabed, Carla Emiliani, Ilaria Tonazzini, Marco G. Cecchini · 2023 · Biomedicines
- Mechanotransduction of Mesenchymal Stem Cells and Hemodynamic ImplicationsTing‐Wei Kao, Yi‐Shiuan Liu, Chih‐Yu Yang, Oscar Kuang‐Sheng Lee · 2023 · The Chinese Journal of Physiology
- Insight to motor clutch model for sensing of ECM residual strainValeria Panzetta, Claudia De Clemente, Michele Russo, Sabato Fusco, Paolo A. Netti · 2023 · Mechanobiology in Medicine
- Mechanical Stimulation of Cells Through Scaffold Design for Tissue EngineeringCarolina Oliver-Urrutia, Ma. Victoria Domínguez García, Jaime Flores‐Estrada, Antonio Laguna‐Camacho, Julieta Castillo-Cadena, Miriam V. Flores‐Merino · 2017 · InTech eBooks
- Mechanosensitivity Occurs along the Adhesome’s Force Train and Affects Traction StressR.J. Asaro, Kuanpo Lin, Qiang Zhu · 2019 · Biophysical Journal
- Time and space modulation of substrate curvature to regulate cell mechanical identityStefania Saporito, Valeria Panzetta, Paolo A. Netti · 2024 · Acta Biomaterialia
- Role of PDE4 Family in Cardiomyocyte Physiology and Heart FailureIvan Sherstnev, Aleksandra Judina, Giovanni Battista Luciani, Alessandra Ghigo, Emilio Hirsch, Julia Gorelik · 2025 · Cells
- Advances in modeling cellular mechanical perceptions and responses via the membrane-cytoskeleton-nucleus machineryHongyuan Zhu, Run Miao, Jin Wang, Min Lin · 2024 · Mechanobiology in Medicine
- Impact of uniaxial cyclic stretching on matrix-associated endothelial cell responsesCuihong Ren, Zhonghua Chang, Kecheng Li, Xiaofeng Wang, Dongfang Wang, Yiyang Xu, Xiaomeng Li, Qian Li · 2024 · Materials Today Bio
- Talin2 binds to non-muscle myosin IIa and regulates cell attachment and fibronectin secretionXiaochuan Wang, Zbigniew Baster, Latifeh Azizi, Liqing Li, Zenon Rajfur, Vesa Pekka Hytönen, Cai Huang · 2024 · Scientific Reports
- A New Player in Tissue Mechanics: MicroRNA Control of Mechanical HomeostasisArturo D’Angelo, Amélie Luise Godeau, Jérôme Solon · 2019 · Developmental Cell
- RAB6B is a potential prognostic marker and correlated with the remolding of tumor immune microenvironment in hepatocellular carcinomaHao Peng, Erwei Zhu, Jitao Wang, Xuanlong Du, Chonggao Wang, Meng Yang, Yewei Zhang · 2022 · Frontiers in Pharmacology
- What are the key mechanical mechanisms governing integrin-mediated cell migration in three-dimensional fiber networks?Daniel Paukner, Jonas F. Eichinger, Christian Johannes Cyron · 2023 · Biomechanics and Modeling in Mechanobiology
- Tumour follower cells: A novel driver of leader cells in collective invasion (Review)Xiaochen Wang, Ya‐ling Tang, Xin‐hua Liang · 2023 · International Journal of Oncology
- Fabrication of Adhesive Substrate for Incorporating Hydrogels to Investigate the Influence of Stiffness on Cancer Cell BehaviorGenaro Vázquez‐Victorio, Adriana Rodríguez-Hernández, Mariel Cano-Jorge, Ana Ximena Monroy-Romero, Marina Macías‐Silva, Mathieu Hautefeuille · 2020 · Methods in molecular biology
- Rational Hydrogel Formulation Leads to Reversible and Enhanced Photocontrolled RigidityJorge Royes, Christophe Coudret, Clément Roux, Florence Benoît‐Marquié, Martine Cazalès, Childérick Séverac, Corinne Lorenzo, Anne‐Françoise Mingotaud · 2017 · ChemPhotoChem
- Multi-scale Modeling of the Heart Valve Interstitial CellAlex Khang, Daniel P. Howsmon, Emma Lejeune, Michael S. Sacks · 2019 · Studies in mechanobiology, tissue engineering and biomaterials
- The laminin-keratin link shields the nucleus from mechanical deformation and signallingZanetta Kechagia, Pablo Sáez, Manuel Gómez‐González, Martín Zamarbide, Ion Andreu, Thijs Koorman, Amy E. M. Beedle, Patrick W.B. Derksen, Xavier Trepat, Marino Arroyo et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Nascent adhesions shorten the period of lamellipodium protrusion through the Brownian ratchet mechanismKeith R. Carney, Akib M. Khan, Samantha Stam, Shiela C. Samson, Nikhil Mittal, Sangyoon J. Han, Tamara C. Bidone, Michelle C. Mendoza · 2023 · Molecular Biology of the Cell
- Recent advances of physiochemical cues on surfaces for directing cell fatesWenwen Deng, Xiufen Yang, Jiangnan Yu, Emmanuel Omari‐Siaw, Ximing Xu · 2025 · Colloids and Surfaces B Biointerfaces
- Tunable Integrin–Ligand Coupling Strength Modulates Cellular Adaptive MechanosensingZheng Zhang, Xiaoxi Liu, Baoyong Sha, Yu Zhang, Lingzhu Zhao, Guoqing Zhao, Jinteng Feng, Ying Zhang, Jin Yang, Zheng Wang et al. · 2025 · Nano Letters
- Current status and future direction of mechanotransduction mechanisms: Perspectives from cell membrane to nucleusYingliang Shi, Jiaqi Yue, Zhuo Wang, Sangang He, Guoliang Sa · 2025 · Biochemical and Biophysical Research Communications
- Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathwayMartina Lerche, Mathilde Mathieu, Hellyeh Hamidi, Megan R. Chastney, Guillaume Jacquemet, Bart M. H. Bruininks, Shreyas Kaptan, Lene Malerød, Nina Marie Pedersen, Andreas Brech et al. · 2025 · The Journal of Cell Biology
- Stabilization of adhesions controls F-actin architecture in mechanotransductionKeith R. Carney, Remi Sondaz, Wesley Sturgess, Kabilan Sakthivel, Jungkyu Kim, Vinay Swaminathan, Tamara C. Bidone · 2025 · Communications Materials
- Tuning the sensitivity of mechanosensory receptors through histidine scanningYuanhao Wang, Yi Wang, Wenjie Yuan, Mingyu Fan, Xiaojing Wang, Anhui Wang, Yanling Bao, Yajing Zhang, Jia Chi Tan, Jianglai Wang et al. · 2026 · Cell
- Pharmacological Blockade of the Adenosine A2B Receptor Is Protective of Proteinuria in Diabetic Rats, through Affecting Focal Adhesion Kinase Activation and the Adhesion Dynamics of PodocytesPablo Mendoza, Claudia Jara, Ángelo Torres, Carlos E. Oyarzun, Gonzalo Antonio Mardones, Claudia Quezada-Monrás, Rody San Martín · 2024 · Cells
- Cell stretching devices integrated with live cell imaging: a powerful approach to study how cells react to mechanical cuesBeatrice Bighi, Gregorio Ragazzini, Alessia Gallerani, Andrea Mescola, Chiara Scagliarini, Chiara Zannini, Martina Marcuzzi, Elena Olivi, Claudia Cavallini, Riccardo Tassinari et al. · 2024 · Progress in Biomedical Engineering
- Tumor Biomechanics-Inspired Future MedicineYuqing Dong, Mengnan Lu, Yuting Yin, Cong Wang, Ningman Dai · 2024 · Cancers
- From cellular to molecular mechanobiologyCheng Zhu, Cho-yin Lee, Larry V. McIntire · 2020 · APL Bioengineering
- Why Stress Matters: An IntroductionDaniel J. Tschumperlin · 2021 · Methods in molecular biology
- A multiscale theory for spreading and migration of adhesion-reinforced mesenchymal cellsWenya Shu, C. Nadir Kaplan · 2023 · Journal of The Royal Society Interface
- A complementary energy approach accommodates scale differences in soft tissuesPablo Sáez, Steven J. Eppell, Roberto Ballarini, José Félix Rodríguez Matas · 2020 · Journal of the Mechanics and Physics of Solids
- Direct Observation of a Coil-to-Helix Contraction Triggered by Vinculin Binding to TalinRafael Tapia‐Rojo, Álvaro Alonso-Caballero, Julio M. Fernández · 2020 · Biophysical Journal
- Mechanotransduction in blood cellsFumihiko Nakamura · 2017 · Blood and Genomics
- Understanding, engineering, and modulating the growth of neural networks: An interdisciplinary approachVidur Raj, C. Jagadish, Vini Gautam · 2021 · Biophysics Reviews
- Tandem tension sensor reveals substrate rigidity-dependence of integrin molecular tensions in live cellsAnwesha Sarkar, Dana N. LeVine, Yuanchang Zhao, Keyvan Mollaeian, Juan Ren, Xuefeng Wang · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Neutrophils exhibit flexible migration strategies and trail formation mechanisms on varying adhesive substratesWenbo Gao, Xiaoning Zhang, Wenhui Hu, Jie Han, Xiaoheng Liu, Yan Zhang, Mian Long · 2024 · Biomaterials
- Cell compression – relevance, mechanotransduction mechanisms and toolsLaura M. Faure, Valeria Venturini, Pere Roca‐Cusachs · 2025 · Journal of Cell Science
- Collagen glycation-mediated mechanical stress aggravates ischemia-reperfusion injuryJing Yang, Yixuan Li, Xiaoxiao Fan, Tong Zhang, Junhai Pan, Si Shen, Cheng Zhong, Duguang Li, Yi Zhang, Guoqiao Chen et al. · 2025 · Acta Biomaterialia
- An oxidized dextran and thiolated chitosan-based hydrogel driven biomimetic triple negative breast cancer 3D in vitro model for cancer progression and therapeutic studiesUnnati Modi, Pooja Makwana, Bindiya Dhimmar, Soundharya Ramu, Mohit Kumar Jolly, Rajesh Vasita · 2025 · Journal of Materials Chemistry B
- Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control NodesAlessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato et al. · 2026 · Advanced Science
- Roles of the Dbl family of RhoGEFs in mechanotransduction – a reviewKazumasa Ohashi, Aoi Kunitomi, Shuhei Chiba, Kensaku Mizuno · 2024 · Frontiers in Cell and Developmental Biology
- KANK1 promotes breast cancer development by compromising Scribble-mediated Hippo activationShiny Shengzhen Guo, Zhiying Liu, Guan Wang, Zhiqi Sun, Kaikai Yu, James P. Fawcett, Reinhard Büttner, Bo Gao, Reinhard Faessler · 2024 · Nature Communications
- Modulation of stem cell response using biodegradable polyester films with different stiffnessSofia Ribeiro, Eugenia Pugliese, Stefanie H. Korntner, Emanuel M. Fernandes, Manuela Estima Gomes, Rui Luís Reis, Yves Bayon, Dimitrios I. Zeugolis · 2021 · Biomedical Engineering Advances
- Biomimetic multifactor stimulation method for analyzing the synergism of matrix stiffness and inorganic polyphosphates on cellular behaviorsXiaonan S. Zheng, Yucheng Sun, Haifang Li, Nan Li, Xueji Zhang, Jin‐Ming Lin · 2022 · Talanta
- Extracellular matrix–dependent mechanosensing and mechanotransductionNatasha Buwa, Nagaraj Balasubramanian · 2022 · Elsevier eBooks
- Mechanical heterogeneity in a soft biomaterial niche controls BMP2 signalingErik Brauer, Aaron Herrera, Raphaela Fritsche‐Guenther, Sophie Görlitz, Hans Leemhuis, Petra I. Knaus, Jennifer Kirwan, Georg N. Duda, Ansgar Petersen · 2024 · Biomaterials
- Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapseHannah C.W. McArthur, Anna T. Bajur, Maro Iliopoulou, Katelyn M. Spillane · 2025 · Proceedings of the National Academy of Sciences
- Inflammatory Cytokines Alter Mesenchymal Stem Cell Mechanosensing and Adhesion on Stiffened Infarct Heart Tissue After Myocardial InfarctionDan Zhu, Peng Wu, Changchen Xiao, Wei Hu, Tongtong Zhang, Xinyang Hu, Wei Chen, Jian’an Wang · 2020 · Frontiers in Cell and Developmental Biology
- Supramolecular Biomaterials in the NetherlandsMatthew Brandon Baker, Anton W. Bosman, Martijn A. J. Cox, Patricia Y. W. Dankers, Aylvin A. Dias, Pascal Jonkheijm, Roxanne E. Kieltyka · 2022 · Tissue Engineering Part A
- A cell retrievable strategy for harvesting extracellular matrix as active biointerfaceXiangyu Dong, Shuxiang Zhang, Yi Ming Xu, Longquan Chen, Qiang Wei, Changsheng Zhao · 2022 · Journal of Material Science and Technology
- Epithelial cell cluster size affects force distribution in response to EGF-induced collective contractilityChiara Zambarda, Carlos Perez Gonzalez, Andreas Schoenit, Nisha Veits, Clara Schimmer, Raimund Jung, Dirk Ollech, Joel Christian, Pere Roca‐Cusachs, Xavier Trepat et al. · 2022 · European Journal of Cell Biology
- Cell adhesion on substrates with variable curvature: Effects on genetic transcription processesÓscar Libardo Rodríguez-Montaño, Lorenzo Santoro, Lorenzo Vaiani, Luciano Lamberti, Antonio Emmanuele Uva, Antonio Boccaccio · 2025 · Computers in Biology and Medicine
- Capped high-force integrin bond lifetimes and spacing-tuned binding frequency drive rapid fibroblast migrationJingjing Feng, Keshu Feng, Zhaohui Xiong, Miao Yu, Yuru Hu, Wenxu Wang, Ruihao Xue, Ze Gong, Zheng Liu, Wei Chen · 2025 · Proceedings of the National Academy of Sciences
- Extracellular matrix restrains cell-cycle progression by nuclear exclusion of Yorkie in DrosophilaLiyuan Sui, Elisabeth Fischer‐Friedrich, Christian Dahmann · 2026 · Current Biology
- An intrinsic cytoskeletal oscillator establishes neuronal polarityTien-chen Lin, Charlotte H. Coles, Eissa Alfadil, Florian Fäßler, Andreas Husch, Sebastián Dupraz, Thorben Pietralla, Akihiro Narita, Max Schelski, Kevin C. Flynn et al. · 2026 · Nature
- On the mechanical response of the actomyosin cortex during cell indentationsJoão P. S. Ferreira, Mei Kuang, Marco Marques, Marco Parente, Margot S. Damaser, Renato Natal Jorge · 2020 · Biomechanics and Modeling in Mechanobiology
- Sustained strain applied at high rates drives dynamic tensioning in epithelial cellsBahareh Tajvidi Safa, Jordan Rosenbohm, Amir Monemian Esfahani, Grayson Minnick, Amir Ostadi Moghaddam, Nickolay V. Lavrik, Changjin Huang, Guillaume Charras, Alexandre Kabla, Ruiguo Yang · 2025 · Communications Biology
- Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8Chun‐Yan Kong, Zhen Guo, Yulan Ma, Mingyu Wang, Haiyang Ni, Pan Wang, Wen‐Jun Qiu, Engui Wang, Zhou Li, Yang Zheng et al. · 2025 · Advanced Science
- Nanomechanics at the extracellular matrix-focal adhesion interfaceRafael Tapia‐Rojo, Sergi Garcia-Manyes · 2025 · Current Opinion in Biomedical Engineering
- Tuning collagen nonlinear mechanics with interpenetrating networks drives adaptive cellular phenotypes in three dimensionsMarco A. Enriquez Martinez, Zhao Wang, Yanina D. Álvarez, Jade E. O’Neill, Robert J. Ju, Petri Turunen, Melanie D. White, Jitendra P. Mata, Elliot Paul Gilbert, Ján Lauko et al. · 2025 · Science Advances
- YAP/TAZ Promote Fibrotic Activity in Human Trabecular Meshwork Cells by Sensing Cytoskeleton Structure AlternationShan Huang, Zhicheng Liu, Xiuqing Qian, Lin Li, Haixia Zhang, Shanshan Li, Shanshan Li · 2022 · Chemosensors
- Steered molecular dynamics simulation of force triggering the integrin αIIbβ3 extension via its ligandKang Wang, Zhenhai Li · 2023 · The European Physical Journal Special Topics
- Solo regulates the localization and activity of PDZ-RhoGEF for actin cytoskeletal remodeling in response to substrate stiffnessAoi Kunitomi, Shuhei Chiba, Nahoko Higashitani, Atsushi Higashitani, Shinichi Sato, Kensaku Mizuno, Kazumasa Ohashi · 2024 · Molecular Biology of the Cell
- Talin1 dysfunction is genetically linked to systemic capillary leak syndromeNaama Elefant, Pinelopi Nikolopoulou, V Vassiliki Papadaki, Danit Oz-Levi, Georgia Rouni, Racheli Sion‐Sarid, William JS Edwards, Christina Arapatzi, Shira Yanovsky‐Dagan, Alana R. Cowell et al. · 2024 · JCI Insight
- Mitosis-Resistant Adhesions Provide Molecular Memory to Dividing CellsGuillaume Jacquemet, Johanna Ivaska · 2018 · Developmental Cell
- Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblastsMartina Lerche, Alberto Elósegui-Artola, Zanetta Kechagia, Camilo Guzmán, Μαρία Γεωργιάδου, Donald Gullberg, Pere Roca‐Cusachs, Emilia Peuhu, Johanna Ivaska · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- α-catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity-dependenceAbhishek Mukherjee, Shay Melamed, Hana Damouny-Khoury, Malak Amer, Lea Feld, Elisabeth Nadjar-Boger, Michael P. Sheetz, Haguy Wolfenson · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Cell response to extracellular matrix energy dissipation outweighs rigidity sensingCarla Huerta-López, Alejandro Clemente-Manteca, Diana Velázquez-Carreras, Francisco M. Espinosa, Juan G. Sanchez, Pablo Sáez, Álvaro Martínez‐del‐Pozo, María García-García, Sara Martín-Colomo, Andrea Rodríguez-Blanco et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Curved adhesions mediate cell attachment to soft matrix fibres in 3DWei Zhang, Chih‐Hao Lu, Melissa L. Nakamoto, Ching‐Ting Tsai, Anish R. Roy, Christina E. Lee, Yang Yang, Zeinab Jahed, Xiao Li, Bianxiao Cui · 2023 · bioRxiv (Cold Spring Harbor Laboratory)