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Genetic Control of the Cell Division Cycle in Yeast

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Brentuximab Vedotin (SGN-35) for Relapsed CD30-Positive Lymphomas

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Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens

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Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

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Multicenter Phase II Trial of YM155, a Small-Molecule Suppressor of Survivin, in Patients With Advanced, Refractory, Non–Small-Cell Lung Cancer

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MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

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Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35)

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Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only

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ATR signaling can drive cells into senescence in the absence of DNA breaks

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Inhibition of DNA and RNA polymerase reactions by chloroquine.

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A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

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The “survivin suppressants” NSC 80467 and YM155 induce a DNA damage response

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Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast

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Interleukin Enhancer-binding Factor 3/NF110 Is a Target of YM155, a Suppressant of Survivin

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Fibronectin Alters Cell Survival and Intracellular Signaling of Confluent A549 Cultures After Irradiation

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Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant

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Biological characterization of MLN944: A potent DNA binding agent

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Identification of a retroviral receptor used by an Envelope protein derived by peptide library screening

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Global gene disruption in human cells to assign genes to phenotypes

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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

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Correlating chemical sensitivity and basal gene expression reveals mechanism of action

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A Call for Systematic Research on Solute Carriers

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Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

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A Pharmacogenomic Landscape in Human Liver Cancers

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Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis

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How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion

Kell, D. B., & Oliver, S. G. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00231 · Cited by 155 · see citing works

SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm

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A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs

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Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

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The metabolome 18 years on: a concept comes of age

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Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import

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The Druggability of Solute Carriers

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Know your target, know your molecule

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GeneGini: Assessment via the Gini Coefficient of Reference “Housekeeping” Genes and Diverse Human Transporter Expression Profiles

O’Hagan, S., Muelas, M. W., Day, P. J., Lundberg, E. K., & Kell, D. B. (2018) · Cell Systems · doi:10.1016/j.cels.2018.01.003 · Cited by 95 · see citing works

Dual pH-Responsive Shell-Cleavable Polycarbonate Micellar Nanoparticles for in Vivo Anticancer Drug Delivery

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Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

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Functional genomics to uncover drug mechanism of action

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An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters

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The potential therapeutic effects of ergothioneine in pre-eclampsia

Kerley, R. N., McCarthy, C., Kell, D. B., & Kenny, L. C. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.12.030 · Cited by 68 · see citing works

The apparent permeabilities of Caco-2 cells to marketed drugs: magnitude, and independence from both biophysical properties and endogenite similarities

O’Hagan, S., & Kell, D. B. (2015) · PeerJ · doi:10.7717/peerj.1405 · Cited by 63 · see citing works

Bioactive Compound Collections: From Design to Target Identification

Laraia, L., Robke, L., & Waldmann, H. (2018) · Chem · doi:10.1016/j.chempr.2018.01.012 · Cited by 61 · see citing works

Protein‐facilitated transport of hydrophobic molecules across the yeast plasma membrane

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The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine

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What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible?

Kell, D. B. (2014) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2014.10.005 · Cited by 54 · see citing works

Role of Passive Diffusion, Transporters, and Membrane Trafficking‐Mediated Processes in Cellular Drug Transport

Cocucci, E., Kim, J., Bai, Y., & Pabla, N. (2016) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.545 · Cited by 54 · see citing works

Molecular Modeling of Drug–Transporter Interactions—An International Transporter Consortium Perspective

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In silico drug repositioning: from large-scale transcriptome data to therapeutics

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Structural basis for the delivery of activated sialic acid into Golgi for sialyation

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Simultaneous Imaging of Endogenous Survivin mRNA and On-Demand Drug Release in Live Cells by Using a Mesoporous Silica Nanoquencher

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A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor

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Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH

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The Transporter-Mediated Cellular Uptake and Efflux of Pharmaceutical Drugs and Biotechnology Products: How and Why Phospholipid Bilayer Transport Is Negligible in Real Biomembranes

Kell, D. B. (2021) · Molecules · doi:10.3390/molecules26185629 · Cited by 48 · see citing works

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network

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Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance

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Recent Advances in Nanomedicine and Survivin Targeting in Brain Cancers

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YM155, a survivin suppressant, triggers PARP-dependent cell death (parthanatos) and inhibits esophageal squamous-cell carcinoma xenografts in mice

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Monitoring Cell-surface N-Glycoproteome Dynamics by Quantitative Proteomics Reveals Mechanistic Insights into Macrophage Differentiation

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Harnessing Solute Carrier Transporters for Precision Oncology

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Drug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancer

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Arrayed mutant haploid embryonic stem cell libraries facilitate phenotype-driven genetic screens

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Gateway to the Golgi: molecular mechanisms of nucleotide sugar transporters

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Quantifying the impact of transporters on cellular drug permeability

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Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9

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Technical approaches to induce selective cell death of pluripotent stem cells

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Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli

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Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier-Mediated Process

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YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway

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Solute carrier family 35 member F2 is indispensable for papillary thyroid carcinoma progression through activation of transforming growth factor‐β type I receptor/apoptosis signal‐regulating kinase 1/mitogen‐activated protein kinase signaling axis

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Membrane transporters in cell physiology, cancer metabolism and drug response

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Implications of endogenous roles of transporters for drug discovery: hitchhiking and metabolite-likeness

Kell, D. B. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2015.44 · Cited by 37 · see citing works

Antiproliferative, DNA intercalation and redox cycling activities of dioxonaphtho[2,3-d]imidazolium analogs of YM155: A structure–activity relationship study

Ho, S. S., Sim, M. Y., Yee, W.-L. S., Yang, T., Yuen, S. P. J., & Go, M. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2015.09.026 · Cited by 35 · see citing works

YM155 sensitizes non-small cell lung cancer cells to EGFR-tyrosine kinase inhibitors through the mechanism of autophagy induction

Dai, C.-H., Shu, Y., Chen, P., Wu, J., Zhu, L.-H., Yuan, R., Long, W., Zhu, Y., & Li, J. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.10.015 · Cited by 34 · see citing works

Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter

Radic-Sarikas, B., Halász, M., Huber, K., Winter, G. E., Tsafou, K. P., Papamarkou, T., Brunak, S., Kölch, W., & Superti‐Furga, G. (2017) · Scientific Reports · doi:10.1038/s41598-017-03129-6 · Cited by 33 · see citing works

The human organic cation transporter OCT1 and its role as a target for drug responses

Brosseau, N., & Ramotar, D. (2019) · Drug Metabolism Reviews · doi:10.1080/03602532.2019.1670204 · Cited by 33 · see citing works

USP32 confers cancer cell resistance to YM155 via promoting ER-associated degradation of solute carrier protein SLC35F2

Chandrasekaran, A. P., Kaushal, K., Park, C., Kim, K.-S., & Ramakrishna, S. (2021) · Theranostics · doi:10.7150/thno.63806 · Cited by 33 · see citing works

Reactive Oxygen Species Synergize To Potently and Selectively Induce Cancer Cell Death

Lee, H. Y., Parkinson, E. I., Granchi, C., Paterni, I., Panigrahy, D., Seth, P., Minutolo, F., & Hergenrother, P. J. (2017) · ACS Chemical Biology · doi:10.1021/acschembio.7b00015 · Cited by 32 · see citing works

Fitting Transporter Activities to Cellular Drug Concentrations and Fluxes: Why the Bumblebee Can Fly

Mendes, P., Oliver, S. G., & Kell, D. B. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.07.006 · Cited by 30 · see citing works

The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells

Wolf, G., Craigon, C., Teoh, S. T., Essletzbichler, P., Onstein, S., Cassidy, D. M., Uijttewaal, E. C. H., Dvorak, V., Cao, Y., Bensimon, A., et al. (2025) · Cell chemical biology · doi:10.1016/j.chembiol.2024.11.009 · Cited by 31 · see citing works

MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites

O’Hagan, S., & Kell, D. B. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00266 · Cited by 29 · see citing works

The Pathognomonic FOXL2 C134W Mutation Alters DNA-Binding Specificity

Carles, A., Trigo‐Gonzalez, G., Cao, Q., Cheng, S., Moksa, M., Bilenky, M., Huntsman, D. D., Morin, G. B., & Hirst, M. (2020) · Cancer Research · doi:10.1158/0008-5472.can-20-0104 · Cited by 30 · see citing works

Causes and Significance of Increased Compound Potency in Cellular or Physiological Contexts

Schwaid, A. G., & Cornella‐Taracido, I. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b00762 · Cited by 29 · see citing works

Quinone-Based Antitumor Agent Sepantronium Bromide (YM155) Causes Oxygen-Independent Redox-Activated Oxidative DNA Damage

Wani, T. H., Surendran, S., Jana, A., Chakrabarty, A., & Chowdhury, G. (2018) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.8b00094 · Cited by 29 · see citing works

SLC35F2–SYVN1–TRIM59 axis critically regulates ferroptosis of pancreatic cancer cells by inhibiting endogenous p53

Che, B., Du, Y., Yuan, R., Xiao, H., Zhang, W., Shao, J., Lu, H., Yu, Y., Xiang, M., Hao, L., et al. (2023) · Oncogene · doi:10.1038/s41388-023-02843-y · Cited by 29 · see citing works

Analysis of drug–endogenous human metabolite similarities in terms of their maximum common substructures

O’Hagan, S., & Kell, D. B. (2017) · Journal of Cheminformatics · doi:10.1186/s13321-017-0198-y · Cited by 26 · see citing works

Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance

Kim, K.-T., Park, J.-C., Jang, H., Lee, H., Park, S., Kim, J., Kwon, O., Go, Y.-H., Jin, Y., Kim, W., et al. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120295 · Cited by 26 · see citing works

Evaluating Cellular Drug Uptake with Fluorescent Sensor Proteins

Scarabelli, S., Tan, K., Griss, R., Hovius, R., D’Alessandro, P. L., Vorherr, T. E., & Johnsson, K. (2017) · ACS Sensors · doi:10.1021/acssensors.7b00331 · Cited by 28 · see citing works

YM155 inhibits topoisomerase function

Hong, M., Ren, M., Silva, J., Paul, A., Wilson, W. D., Schroeder, C., Weinberger, P., Janik, J. E., & Hao, Z. (2016) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000000441 · Cited by 26 · see citing works

Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine

Grixti, J. M., O’Hagan, S., Day, P. J., & Kell, D. B. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00155 · Cited by 27 · see citing works

The mystery of the human proton-organic cation antiporter: One transport protein or many?

Sachkova, A., Jensen, O., Dücker, C., Ansari, S., & Brockmöller, J. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108283 · Cited by 25 · see citing works

Functional Investigation of Solute Carrier Family 35, Member F2, in Three Cellular Models of the Primate Blood-Brain Barrier

Mochizuki, T., Mizuno, T., Kurosawa, T., Yamaguchi, T., Higuchi, K., Tega, Y., Nozaki, Y., Kawabata, K., Deguchi, Y., & Kusuhara, H. (2020) · Drug Metabolism and Disposition · doi:10.1124/dmd.120.000115 · Cited by 25 · see citing works

d-a-Tocopheryl Polyethylene Glycol 1000 Succinate and a small-molecule Survivin suppressant synergistically induce apoptosis in SKBR3 breast cancer cells

Neophytou, C. M., Mesaritis, A., Gregoriou, G., & Constantinou, A. I. (2019) · Scientific Reports · doi:10.1038/s41598-019-50884-9 · Cited by 24 · see citing works

A combination of YM-155, a small molecule survivin inhibitor, and IL-2 potently suppresses renal cell carcinoma in murine model

Guo, K. X., Huang, P., Xu, N., Xu, P., Kaku, H., Zheng, S., Xu, A., Matsuura, E., Liu, C., & Kumon, H. (2015) · Oncotarget · doi:10.18632/oncotarget.4121 · Cited by 23 · see citing works

In silico Prioritization of Transporter–Drug Relationships From Drug Sensitivity Screens

César‐Razquin, A., Girardi, E., Yang, M., Brehme, M., Sáez-Rodríguez, J., & Superti‐Furga, G. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01011 · Cited by 23 · see citing works

Small Molecule Inhibitors Targeting the “Undruggable” Survivin: The Past, Present, and Future from a Medicinal Chemist’s Perspective

Cui, Q., Huang, C., Liu, J., & Zhang, J. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c01130 · Cited by 23 · see citing works

The over-expression of survivin enhances the chemotherapeutic efficacy of YM155 in human hepatocellular carcinoma

Xia, H., Chen, J., Shi, M., Deivasigamani, A., Ooi, L. L., & Hui, K. M. (2015) · Oncotarget · doi:10.18632/oncotarget.3337 · Cited by 23 · see citing works

Hyperthermia induces apoptosis by targeting Survivin in esophageal cancer

Qin, S., Xu, C., Li, S., Wang, X., Sun, X., Wang, P., Zhang, B., & Ren, H. (2015) · Oncology Reports · doi:10.3892/or.2015.4252 · Cited by 23 · see citing works

Hunting Viral Receptors Using Haploid Cells

Pillay, S., & Carette, J. E. (2015) · Annual Review of Virology · doi:10.1146/annurev-virology-100114-055119 · Cited by 23 · see citing works

Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155

Nyquist, M. D., Corella, A. N., Burns, J., Coleman, I. M., Gao, S., Tharakan, R., Riggan, L., Cai, C., Corey, E., Nelson, P. S., et al. (2017) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-16-0315 · Cited by 23 · see citing works

SLC35F2, a Transporter Sporadically Mutated in the Untranslated Region, Promotes Growth, Migration, and Invasion of Bladder Cancer Cells

Kotolloshi, R., Hölzer, M., Gajda, M. R., Grimm, M., & Steinbach, D. (2021) · Cells · doi:10.3390/cells10010080 · Cited by 22 · see citing works

The transporter-mediated cellular uptake of pharmaceutical drugs is based on their metabolite-likeness and not on their bulk biophysical properties: Towards a systems pharmacology

Kell, D. B. (2015) · Perspectives in Science · doi:10.1016/j.pisc.2015.06.004 · Cited by 21 · see citing works

Systematic identification of biomarker-driven drug combinations to overcome resistance

Rees, M. G., Brenan, L., DoCarmo, M., Duggan, P., Bajrami, B., Arciprete, M., Boghossian, A. S., Vaimberg, E. W., Ferrara, S. J., Lewis, T. A., et al. (2022) · Nature Chemical Biology · doi:10.1038/s41589-022-00996-7 · Cited by 21 · see citing works

Metabolic mapping of the human solute carrier superfamily

Wiedmer, T., Teoh, S. T., Christodoulaki, E., Wolf, G., Tian, C., Sedlyarov, V., Jarret, A. P., Leippe, P., Frommelt, F., Inglés‐Prieto, Á., et al. (2025) · Molecular Systems Biology · doi:10.1038/s44320-025-00106-4 · Cited by 21 · see citing works

The solute carrier superfamily interactome

Frommelt, F., Ladurner, R., Goldmann, U., Wolf, G., Inglés‐Prieto, Á., Liñeiro, E., Gelová, Z., Hopp, A.-K., Christodoulaki, E., Teoh, S. T., et al. (2025) · Molecular Systems Biology · doi:10.1038/s44320-025-00109-1 · Cited by 20 · see citing works

The small molecule survivin inhibitor YM155 may be an effective treatment modality for colon cancer through increasing apoptosis

Li, W. L., Lee, M.-R., & Cho, M.-Y. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.02.009 · Cited by 20 · see citing works

Recent advances in understanding hepatic drug transport

Stieger, B., & Hagenbuch, B. (2016) · F1000Research · doi:10.12688/f1000research.9466.1 · Cited by 19 · see citing works

Antimalarial N1,N3-Dialkyldioxonaphthoimidazoliums: Synthesis, Biological Activity, and Structure–activity Relationships

Ahenkorah, S., Coertzen, D., Tong, J. X., Fridianto, K. T., Wittlin, S., Birkholtz, L., Tan, K. S. W., Lam, Y., Go, M., & Haynes, R. K. (2019) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.9b00457 · Cited by 19 · see citing works

Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in Escherichia coli

Salcedo-Sora, J. E., Robison, A. T. R., Zaengle-Barone, J. M., Franz, K. J., & Kell, D. B. (2021) · Molecules · doi:10.3390/molecules26195826 · Cited by 17 · see citing works

Toxicogenetic evaluation of dichlorophene in peripheral blood and in the cells of the immune system using molecular and flow cytometric approaches

Lone, I. M., Nabi, A., Dar, N. J., Hussain, A., Nazam, N., Hamid, A., & Ahmad, W. (2016) · Chemosphere · doi:10.1016/j.chemosphere.2016.08.131 · Cited by 19 · see citing works

A Cell Type Selective YM155 Prodrug Targets Receptor-Interacting Protein Kinase 2 to Induce Brain Cancer Cell Death

West, T. J., Bi, J., Martínez‐Peña, F., Curtis, E. J., Gazaniga, N. R., Mischel, P. S., & Lairson, L. L. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.2c11715 · Cited by 16 · see citing works

Selection of Effective Therapies Using Three-Dimensional in vitro Modeling of Chondrosarcoma

Palubeckaitė, I., Venneker, S., Bruijn, I. H. B., van den Akker, B. E., Krol, A. D. G., Gelderblom, H. A. J., & Bovée, J. V. M. G. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.566291 · Cited by 16 · see citing works

A protet-based, protonic charge transfer model of energy coupling in oxidative and photosynthetic phosphorylation

Kell, D. B. (2021) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/bs.ampbs.2021.01.001 · Cited by 16 · see citing works

Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells

Go, Y., Lim, C., Jeong, H.-C., Kwon, O.-S., Chung, S., Lee, H., Kim, W., Suh, Y., Son, W.-S., Lee, M.-O., et al. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00298 · Cited by 13 · see citing works

Generation of reactive oxygen species is the primary mode of action and cause of survivin suppression by sepantronium bromide (YM155)

Wani, T. H., Chowdhury, G., & Chakrabarty, A. (2021) · RSC Medicinal Chemistry · doi:10.1039/d0md00383b · Cited by 15 · see citing works

Application of CRISPR-Cas9 System to Study Biological Barriers to Drug Delivery

He, J., Biswas, R., Bugde, P., Li, J., Liu, D., & Li, Y. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14050894 · Cited by 15 · see citing works

Inhibition of Sp1-mediated survivin and MCL1 expression cooperates with SLC35F2 and myeloperoxidase to modulate YM155 cytotoxicity to human leukemia cells

Chiou, J., Lee, Y., Huang, C., Wang, L., Shi, Y., & Chang, L. (2021) · Biochemical Pharmacology · doi:10.1016/j.bcp.2021.114544 · Cited by 15 · see citing works

Screening compound libraries for H2O2-mediated cancer therapeutics using a peroxiredoxin-based sensor

Hao, Y., Langford, T. F., Moon, S. J., Eller, K. A., & Sikes, H. D. (2021) · Cell chemical biology · doi:10.1016/j.chembiol.2021.09.003 · Cited by 15 · see citing works

High doses of alcohol during pregnancy cause DNA damages in osteoblasts of newborns rats

Carvalho, I. C. S., Dutra, T. P., de Andrade, D. P., Balducci, I., Soares, C. P., & da Rocha, R. F. (2015) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.23468 · Cited by 14 · see citing works

Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer

Kangaspeska, S., Hultsch, S., Jaiswal, A., Edgren, H., Mpindi, J.-P., Eldfors, S., Brück, O. E., Aittokallio, T. A., & Kallioniemi, O. (2016) · BMC Cancer · doi:10.1186/s12885-016-2452-5 · Cited by 14 · see citing works

Biotoxins Mediated DNA Damage and Role of Phytochemicals in DNA Protection

Singh, N., & Sharma, B. (2018) · Biochemistry & Molecular Biology Journal · doi:10.21767/2471-8084.100054 · Cited by 14 · see citing works

SLC35F2 in Cancer Development and Progression

Shen, S., Tang, Z., Guo, C., 李四喜, Chen, A., Gu, C., & Mi, Y. (2026) · Journal of Cellular Physiology · doi:10.1002/jcp.70238

Effect of Sepatronium Bromide (YM-155) on DNA Double-Strand Breaks Repair in Cancer Cells

Majera, D., & Mistrík, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249431 · Cited by 13 · see citing works

Antiproliferative, DNA intercalation and redox cycling activities of dioxonaphtho[2,3-d]imidazolium analogs of YM155: A structure–activity relationship study

Ho, S. S., Sim, M. Y., Yee, W.-L. S., Yang, T., Yuen, S. P. J., & Go, M. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2015.09.026 · Cited by 35 · see citing works

The Mechanism of Radiosensitization by YM155, a Novel Small Molecule Inhibitor of Survivin Expression, is Associated with DNA Damage Repair

Hu, S., Fu, S., Xu, X., Chen, L., Xu, J., Li, B., Qu, Y., Yu, H., Lü, S., & Li, W. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000430245 · Cited by 29 · see citing works

Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression

Chiou, J., & Chang, L. (2023) · APOPTOSIS · doi:10.1007/s10495-023-01918-1 · Cited by 10 · see citing works