The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Reprogramming bacteria to seek and destroy an herbicide
Open accessAbstract
A major goal of synthetic biology is to reprogram cells to perform complex tasks. Here we show how a combination of in vitro and in vivo selection rapidly identifies a synthetic riboswitch that activates protein translation in response to the herbicide atrazine. We further demonstrate that this riboswitch can reprogram bacteria to migrate in the presence of atrazine. Finally, we show that incorporating a gene from an atrazine catabolic pathway allows these cells to seek and destroy atrazine.
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Cites
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Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection
Baba, T., Ara, T., Hasegawa, M., Takai, Y., Okumura, Y., Baba, M., Datsenko, K. A., Tomita, M., Wanner, B. L., & Mori, H. (2006) · Molecular Systems Biology · doi:10.1038/msb4100050 · Cited by 7,858
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In-Line Probing Analysis of Riboswitches
Regulski, E. E., & Breaker, R. R. (2008) · Methods In Molecular Biology™ · doi:10.1007/978-1-59745-033-1_4 · Cited by 338
Cited by
Serganov, A., & Nudler, E. (2013) · Cell · doi:10.1016/j.cell.2012.12.024 · Cited by 1,013
Engineering microbes to sense and eradicate Pseudomonas aeruginosa , a human pathogen
Saeidi, N., Wong, C. K., Lo, T., Nguyen, H. X., Ling, H., Leong, S. S. J., Poh, C. L., & Chang, M. W. (2011) · Molecular Systems Biology · doi:10.1038/msb.2011.55 · Cited by 369
Control theory meets synthetic biology
Del Vecchio, D., Dy, A. J., & Qian, Y. (2016) · Journal of The Royal Society Interface · doi:10.1098/rsif.2016.0380 · Cited by 283
Themes and variations in riboswitch structure and function
Peselis, A., & Serganov, A. (2014) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2014.02.012 · Cited by 102
Aptamer base: a collaborative knowledge base to describe aptamers and SELEX experiments
Cruz-Toledo, J., McKeague, M., Zhang, X., Giamberardino, A., McConnell, E., Francis, T., DeRosa, M. C., & Dumontier, M. (2012) · Database · doi:10.1093/database/bas006 · Cited by 95
Metadata
- Authors
- Sinha, J., Reyes, S. J., & Gallivan, J. P.
- Venue
- Nature Chemical Biology
- Published
- 2010-05-09
- Volume
- 6
- Issue
- 6
- Pages
- 464-470
- ISSN
- 1552-4450 (ISSN-L)
- 1552-4469
- OpenAlex
- W2028570435
- Cited by
- 166
- References
- 4
- FWCI
- 11.46
- Type
- journal article
- Language
- en
- Status
- Retracted
- Open access
- green
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- Sinha, J., Reyes, S. J., & Gallivan, J. P. (2010). Reprogramming bacteria to seek and destroy an herbicide. Nature Chemical Biology. https://doi.org/10.1038/nchembio.369
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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