The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel
Open accessAbstract
Arabidopsis thaliana is native to Eurasia and is naturalized across the world. Its ability to be easily propagated and its high phenotypic variability make it an ideal model system for functional, ecological and evolutionary genetics. To date, analyses of the natural genetic variation of A. thaliana have involved small numbers of individual plants or genetic markers. Here we genotype 1,307 worldwide accessions, including several regional samples, using a 250K SNP chip. This allowed us to produce a high-resolution description of the global pattern of genetic variation. We applied three complementary selection tests and identified new targets of selection. Further, we characterized the pattern of historical recombination in A. thaliana and observed an enrichment of hotspots in its intergenic regions and repetitive DNA, which is consistent with the pattern that is observed for humans but which is strikingly different from that observed in other plant species. We have made the seeds we used to produce this Regional Mapping (RegMap) panel publicly available. This panel comprises one of the largest genomic mapping resources currently available for global natural isolates of a non-human species.
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Population Structure and Eigenanalysis
Patterson, N., Price, A. L., & Reich, D. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020190 · Cited by 5,280
The hitch-hiking effect of a favourable gene
Smith, J. M., & Haigh, J. (1974) · Genetical Research · doi:10.1017/s0016672300014634 · Cited by 3,415
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines
Atwell, S., Huang, Y. S., Vilhjálmsson, B. J., Willems, G., Horton, M., Li, Y., Meng, D., Platt, A., Tarone, A. M., Hu, T. T., et al. (2010) · Nature · doi:10.1038/nature08800 · Cited by 1,780
Self-citationThe genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation
Pritchard, J. K., Pickrell, J. K., & Coop, G. (2010) · Current Biology · doi:10.1016/j.cub.2009.11.055 · Cited by 932 · cited 1×
“Because PHS, CLR and F ST analyses identify loci at different stages in the selection process or loci that are experiencing different modes of adaptatio”
BackgroundDrive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination
Myers, S., Bowden, R., Tumian, A., Bontrop, R. E., Freeman, C., MacFie, T. S., McVean, G., & Donnelly, P. (2010) · Science · doi:10.1126/science.1182363 · Cited by 683
Ohno's dilemma: Evolution of new genes under continuous selection
Bergthorsson, U., Andersson, D. I., & Roth, J. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707158104 · Cited by 405 · cited 1×
“Recombination-mediated amplification of genes can facilitate adaptive evolution by increasing the mutational target siz”
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Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters
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“…to the pattern of genetic correlations, we fitted multi-trait QTL mixed models (MTMMs) to the total set of 30 traits, using a 214 000 SNP set that is commonly used for GWAS in Arabidopsis (Kim et al. , 2007; Atwell et al. , 2010; Li et al. , 2010; Horton et al. , 2012; Bac-Molenaar et al. , 2015).”
Molecular, genetic and evolutionary analysis of a paracentric inversion in Arabidopsis thaliana
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Metadata
- Authors
- Horton, M. W., Hancock, A. M., Huang, Y. S., Toomajian, C., Atwell, S., Auton, A., Muliyati, N. W., Platt, A., Sperone, F. G., Vilhjálmsson, B. J., Nordborg, M., Borevitz, J. O., & Bergelson, J.
- Venue
- Nature Genetics
- Published
- 2012-01-08
- Volume
- 44
- Issue
- 2
- Pages
- 212-216
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2030444684
- Cited by
- 543
- References
- 6
- FWCI
- 23.92
- Type
- journal article
- Language
- en
- Open access
- green
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- Horton, M. W., Hancock, A. M., Huang, Y. S., Toomajian, C., Atwell, S., Auton, A., Muliyati, N. W., Platt, A., Sperone, F. G., Vilhjálmsson, B. J., Nordborg, M., Borevitz, J. O., & Bergelson, J. (2012). Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nature Genetics. https://doi.org/10.1038/ng.1042
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