The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development
Open accessAbstract
Using the latest sequencing and optical mapping technologies, we have produced a high-quality de novo assembly of the apple (Malus domestica Borkh.) genome. Repeat sequences, which represented over half of the assembly, provided an unprecedented opportunity to investigate the uncharacterized regions of a tree genome; we identified a new hyper-repetitive retrotransposon sequence that was over-represented in heterochromatic regions and estimated that a major burst of different transposable elements (TEs) occurred 21 million years ago. Notably, the timing of this TE burst coincided with the uplift of the Tian Shan mountains, which is thought to be the center of the location where the apple originated, suggesting that TEs and associated processes may have contributed to the diversification of the apple ancestor and possibly to its divergence from pear. Finally, genome-wide DNA methylation data suggest that epigenetic marks may contribute to agronomically relevant aspects, such as apple fruit development.
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Cites
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Cited by
15 years of GDR: New data and functionality in the Genome Database for Rosaceae
Jung, S., Lee, T., Cheng, C.-H., Buble, K., Zheng, P., Yu, J., Humann, J., Ficklin, S. P., Gasic, K., Scott, K., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gky1000 · Cited by 459
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The population genetics of structural variants in grapevine domestication
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Efficient Targeted Mutagenesis in Apple and First Time Edition of Pear Using the CRISPR-Cas9 System
Charrier, A., Vergne, E., Dousset, N., Richer, A., Petiteau, A., & Chevreau, E. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.00040 · Cited by 253
Metadata
- Authors
- Daccord, N., Celton, J.-M., Linsmith, G., Becker, C., Choisne, N., Schijlen, E., van de Geest, H., Bianco, L., Micheletti, D., Velasco, R., Di Pierro, E. A., Gouzy, J., Rees, D. J. G., Guérif, P., Muranty, H., Durel, C.-E., Laurens, F., Lespinasse, Y., Gaillard, S., Aubourg, S., Quesneville, H., Weigel, D., van de Weg, E., Troggio, M., & Bucher, E.
- Venue
- Nature Genetics
- Published
- 2017-06-05
- Volume
- 49
- Issue
- 7
- Pages
- 1099-1106
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2623998041
- Cited by
- 982
- References
- 73
- FWCI
- 77.20
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Daccord, N., Celton, J.-M., Linsmith, G., Becker, C., Choisne, N., Schijlen, E., van de Geest, H., Bianco, L., Micheletti, D., Velasco, R., Di Pierro, E. A., Gouzy, J., Rees, D. J. G., Guérif, P., Muranty, H., Durel, C.-E., Laurens, F., Lespinasse, Y., Gaillard, S., . . . Bucher, E. (2017). High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development. Nature Genetics. https://doi.org/10.1038/ng.3886
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
