Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 289

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

Open access
The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology, Kote-Jarai, Zsofia, The UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource, The PRACTICAL Consortium, Olama, Ali Amin Al, Giles, Graham G, Severi, Gianluca, Schleutker, Johanna, Weischer, Maren, Campa, Daniele, Riboli, Elio, Key, Tim, Gronberg, Henrik, Hunter, David J, Kraft, Peter, Thun, Michael J, Ingles, Sue, Chanock, Stephen, Albanes, Demetrius, Hayes, Richard B, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, Pharoah, Paul, Schumacher, Fredrick, Henderson, Brian E, Stanford, Janet L, Ostrander, Elaine A, Sorensen, Karina Dalsgaard, Dörk, Thilo, Andriole, Gerald, Dickinson, Joanne L, Cybulski, Cezary, Lubinski, Jan, Spurdle, Amanda, Clements, Judith A, Chambers, Suzanne, Aitken, Joanne, Gardiner, R A Frank, Thibodeau, Stephen N, Schaid, Dan, John, Esther M, Maier, Christiane, Vogel, Walther, Cooney, Kathleen A, Park, Jong Y, Cannon-Albright, Lisa, Brenner, Hermann, Habuchi, Tomonori, Zhang, Hong-Wei, Lu, Yong-Jie, Kaneva, Radka, Muir, Ken, Benlloch, Sara, Leongamornlert, Daniel A, Saunders, Edward J, Tymrakiewicz, Malgorzata, Mahmud, Nadiya, Guy, Michelle, O'Brien, Lynne T, Wilkinson, Rosemary A, Hall, Amanda L, Sawyer, Emma J, Dadaev, Tokhir, Morrison, Jonathan, Dearnaley, David P, Horwich, Alan, Huddart, Robert A, Khoo, Vincent S, Parker, Christopher C, Van As, Nicholas, Woodhouse, Christopher J, Thompson, Alan, Christmas, Tim, Ogden, Chris, Cooper, Colin S, Lophatonanon, Aritaya, Southey, Melissa C, Hopper, John L, English, Dallas R, Wahlfors, Tiina, Tammela, Teuvo L J, Klarskov, Peter, Nordestgaard, Børge G, Røder, M Andreas, Tybjærg-Hansen, Anne, Bojesen, Stig E, Travis, Ruth, Canzian, Federico, Kaaks, Rudolf, Wiklund, Fredrik, Aly, Markus, Lindstrom, Sara, Diver, W Ryan, Gapstur, Susan, Stern, Mariana C, Corral, Roman, Virtamo, Jarmo, Cox, Angela, Haiman, Christopher A, Le Marchand, Loic, FitzGerald, Liesel, Kolb, Suzanne, Kwon, Erika M, Karyadi, Danielle M, Ørntoft, Torben Falck, Borre, Michael, Meyer, Andreas, Serth, Jürgen, Yeager, Meredith, Berndt, Sonja I, Marthick, James R, Patterson, Briony, Wokolorczyk, Dominika, Batra, Jyotsna, Lose, Felicity, McDonnell, Shannon K, Joshi, Amit D, Shahabi, Ahva, Rinckleb, Antje E, Ray, Ana, Sellers, Thomas A, Lin, Hui-Yi, Stephenson, Robert A, Farnham, James, Muller, Heiko, Rothenbacher, Dietrich, Tsuchiya, Norihiko, Narita, Shintaro, Cao, Guang-Wen, Slavov, Chavdar, Mitev, Vanio, Easton, Douglas F, Eeles, Rosalind A·2011·Nature Genetics
DOI 10.1038/ng.882
Open this paper in CoChat — free account

Abstract

Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. We conducted a multi-stage genome-wide association study for PrCa and previously reported the results of the first two stages, which identified 16 PrCa susceptibility loci. We report here the results of stage 3, in which we evaluated 1,536 SNPs in 4,574 individuals with prostate cancer (cases) and 4,164 controls. We followed up ten new association signals through genotyping in 51,311 samples in 30 studies from the Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome (PRACTICAL) consortium. In addition to replicating previously reported loci, we identified seven new prostate cancer susceptibility loci on chromosomes 2p11, 3q23, 3q26, 5p12, 6p21, 12q13 and Xq12 (P = 4.0 × 10−8 to P = 2.7 × 10−24). We also identified a SNP in TERT more strongly associated with PrCa than that previously reported. More than 40 PrCa susceptibility loci, explaining ∼25% of the familial risk in this disease, have now been identified.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/ng.882

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 2 references

Cited by

See all 289

Metadata

Authors
The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology, Kote-Jarai, Z., The UK ProtecT Study Collaborators, T. A. P. C. B., The PRACTICAL Consortium, Olama, A. A. A., Giles, G. G., Severi, G., Schleutker, J., Weischer, M., Campa, D., Riboli, E., Key, T., Gronberg, H., Hunter, D. J., Kraft, P., Thun, M. J., Ingles, S., Chanock, S., Albanes, D., Hayes, R. B., Neal, D. E., Hamdy, F. C., Donovan, J. L., Pharoah, P., Schumacher, F., Henderson, B. E., Stanford, J. L., Ostrander, E. A., Sorensen, K. D., Dörk, T., Andriole, G., Dickinson, J. L., Cybulski, C., Lubinski, J., Spurdle, A., Clements, J. A., Chambers, S., Aitken, J., Gardiner, R. A. F., Thibodeau, S. N., Schaid, D., John, E. M., Maier, C., Vogel, W., Cooney, K. A., Park, J. Y., Cannon-Albright, L., Brenner, H., Habuchi, T., Zhang, H.-W., Lu, Y.-J., Kaneva, R., Muir, K., Benlloch, S., Leongamornlert, D. A., Saunders, E. J., Tymrakiewicz, M., Mahmud, N., Guy, M., O'Brien, L. T., Wilkinson, R. A., Hall, A. L., Sawyer, E. J., Dadaev, T., Morrison, J., Dearnaley, D. P., Horwich, A., Huddart, R. A., Khoo, V. S., Parker, C. C., Van As, N., Woodhouse, C. J., Thompson, A., Christmas, T., Ogden, C., Cooper, C. S., Lophatonanon, A., Southey, M. C., Hopper, J. L., English, D. R., Wahlfors, T., Tammela, T. L. J., Klarskov, P., Nordestgaard, B. G., Røder, M. A., Tybjærg-Hansen, A., Bojesen, S. E., Travis, R., Canzian, F., Kaaks, R., Wiklund, F., Aly, M., Lindstrom, S., Diver, W. R., Gapstur, S., Stern, M. C., Corral, R., Virtamo, J., Cox, A., Haiman, C. A., Le Marchand, L., FitzGerald, L., Kolb, S., Kwon, E. M., Karyadi, D. M., Ørntoft, T. F., Borre, M., Meyer, A., Serth, J., Yeager, M., Berndt, S. I., Marthick, J. R., Patterson, B., Wokolorczyk, D., Batra, J., Lose, F., McDonnell, S. K., Joshi, A. D., Shahabi, A., Rinckleb, A. E., Ray, A., Sellers, T. A., Lin, H.-Y., Stephenson, R. A., Farnham, J., Muller, H., Rothenbacher, D., Tsuchiya, N., Narita, S., Cao, G.-W., Slavov, C., Mitev, V., Easton, D. F., & Eeles, R. A.
Venue
Nature Genetics
Publisher
Springer Science and Business Media LLC
Published
2011-07-10
Volume
43
Issue
8
Pages
785-791
ISSN
  • 1061-4036 (ISSN-L)
  • 1546-1718
DOI
10.1038/ng.882
OpenAlex
W2063993913
Cited by
289
References
2
FWCI
22.84
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. https://app.cochat.ai/papers/10.1038/ng.882
The paper
The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology, Kote-Jarai, Z., The UK ProtecT Study Collaborators, T. A. P. C. B., The PRACTICAL Consortium, Olama, A. A. A., Giles, G. G., Severi, G., Schleutker, J., Weischer, M., Campa, D., Riboli, E., Key, T., Gronberg, H., Hunter, D. J., Kraft, P., Thun, M. J., Ingles, S., Chanock, S., Albanes, D., . . . Eeles, R. A. (2011). Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nature Genetics. https://doi.org/10.1038/ng.882

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.