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The fragile X mental retardation protein is associated with ribosomes

Khandjian, Edouard W., Corbin, François, Woerly, Stephane, Rousseau, François·1996·Nature Genetics

DOI 10.1038/ng0196-91

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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
Verkerk, A. J. M. H., Pieretti, M., Sutcliffe, J. S., Fu, Y.-H., Kuhl, D. P. A., Pizzuti, A., Reiner, O., Richards, S., Victoria, M. F., Zhang, F., et al. (1991) · Cell · doi:10.1016/0092-8674(91)90397-h · Cited by 3,481
Instability of a 550-Base Pair DNA Segment and Abnormal Methylation in Fragile X Syndrome
Oberlé, I., Rousseau, F., Heitz, D., Kretz, C., Devys, D., Hanauer, A., Boué, J., Bertheas, M. F., & Mandel, J. L. (1991) · Science · doi:10.1126/science.252.5009.1097 · Cited by 1,499
Self-citation
Absence of expression of the FMR-1 gene in fragile X syndrome
Pieretti, M., Zhang, F., Fu, Y.-H., Warren, S. T., Oostra, B. A., Caskey, C. T., & Nelson, D. L. (1991) · Cell · doi:10.1016/0092-8674(91)90125-i · Cited by 1,476
Fmr1 knockout mice: A model to study fragile X mental retardation
THEDUTCHBELGIANFRAGILEXCONSOR (1994) · Cell · doi:10.1016/0092-8674(94)90569-x · Cited by 1,108
Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n
Kremer, E., Pritchard, M., Lynch, M., Yu, S., Holman, K., Baker, E., Warren, S., Schlessinger, D., Sutherland, G., & Richards, R. (1991) · Science · doi:10.1126/science.1675488 · Cited by 929
The FMR–1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation
Devys, D., Lutz, Y., Rouyer, N., Bellocq, J., & Mandel, J. (1993) · Nature Genetics · doi:10.1038/ng0893-335 · Cited by 781
Histology. A Text and Atlas.
Ross, M. (1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-81-2-286_5 · Cited by 758
FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding
Ashley, C. T., Wilkinson, K. D., Reines, D., & Warren, S. T. (1993) · Science · doi:10.1126/science.7692601 · Cited by 752
Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.
Lerner, E. A., Lerner, M. R., Janeway, C. A., & STEITZ, J. A. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.5.2737 · Cited by 718
DNA methylation represses FMR-1 transcription in fragile X syndrome
Sutcliffe, J. S., Nelson, D. L., Zhang, F., Pieretti, M., Caskey, C. T., Saxe, D., & Warren, S. T. (1992) · Human Molecular Genetics · doi:10.1093/hmg/1.6.397 · Cited by 680

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Goodwin, G.H. & Dahlberg, A.E. Electrophoresis of nucleoproteins. In Gel electrophoresis of nucleic acids: a practical approach, (eds Rickwood, D. & Hames, B.D.) 199–225 (IRL Press, Oxford, 1982).
Schwartz, J.H. Synthesis and trafficking of neuronal proteins. In Principles of neuronal science, (eds Kandel, E.R., Schwartz, J.H. & Jessell, T.M.) (Appleton Lange,Norwalk,1992).

Sorted by citations

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Tamanini, F. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.10.1487 · Cited by 63
Mutational analysis of the FMR1 gene in 118 mentally retarded males suspected of fragile X syndrome: absence of prevalent mutations
Grønskov, K., Hallberg, A., & Brøndum‐Nielsen, K. (1998) · Human Genetics · doi:10.1007/s004390050718 · Cited by 58
The translational regulator FMRP controls lipid and glucose metabolism in mice and humans
Leboucher, A., Pisani, D. F., Martinez-Gili, L., Chilloux, J., Bermudez-Martin, P., Van Dijck, A., Ganief, T., Macek, B., Becker, J. A. J., Le Merrer, J., et al. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.01.002 · Cited by 56
Muscle Specific Fragile X Related Protein 1 Isoforms are Sequestered in the Nucleus of Undifferentiated Myoblast
Dubé, M., Huot, M., & Khandjian, É. W. (2000) · BMC Genetics · doi:10.1186/1471-2156-1-4 · Cited by 56
Translational Control at the Synapse
Wang, H., & Tiedge, H. (2004) · The Neuroscientist · doi:10.1177/1073858404265866 · Cited by 55
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Bonaccorso, C. M., Spatuzza, M., Di Marco, B., Gloria, A., Barrancotto, G., Cupo, A., Musumeci, S. A., D'Antoni, S., Bardoni, B., & Catania, M. V. (2015) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2015.02.004 · Cited by 52
Insights into brain development from neurogenetic syndromes: evidence from fragile X syndrome, Williams syndrome, Turner syndrome and velocardiofacial syndrome
Walter, E., Mazaika, P. K., & Reiss, A. L. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.04.033 · Cited by 55
UVC-Induced Stress Granules in Mammalian Cells
Moutaoufik, M. T., Fatimy, R. E., Nassour, H., Gareau, C., Lang, J., Tanguay, R. M., Mazrouï, R., & Khandjian, É. W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112742 · Cited by 53
Screening for Fragile X Syndrome: Information Needs for Health Planners
Murray, J., Cuckle, H., Taylor, G., & Hewison, J. (1997) · Journal of Medical Screening · doi:10.1177/096914139700400204 · Cited by 48
Translation regulation of mRNAs by the fragile X family of proteins through the microRNA pathway
Cheever, A., & Ceman, S. (2009) · RNA Biology · doi:10.4161/rna.6.2.8196 · Cited by 49
An assessment of screening strategies for fragile X syndrome in the UK
Pembrey, M. E., Barnicoat, A. J., Carmichael, B., Bobrow, M., & TURNER, G. M. (2001) · Health Technology Assessment · doi:10.3310/hta5070 · Cited by 48
The effect of FMR1 CGG repeat interruptions on mutation frequency as measured by sperm typing.
Kunst, C. B., Leeflang, E. P., Iber, J. C., Arnheim, N., & Warren, S. T. (1997) · Journal of Medical Genetics · doi:10.1136/jmg.34.8.627 · Cited by 48
Come FLY with us: toward understanding fragile X syndrome
Zarnescu, D. C., Shan, G., Warren, S. T., & Jin, P. (2005) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2005.00136.x · Cited by 47
Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer
Majumder, M., Johnson, R. H., & Palanisamy, V. (2020) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2020.1810621 · Cited by 50
Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships
Tucker, B., Richards, R. I., & Lardelli, M. T. (2004) · Development Genes and Evolution · doi:10.1007/s00427-004-0438-9 · Cited by 45
The Fragile X Protein and Genome Function
Dockendorff, T. C., & Labrador, M. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1122-9 · Cited by 41
Fragile X syndrome, the Fragile X related proteins, and animal models
Hoogeveen, A. T., Willemsen, R., & Oostra, B. A. (2002) · Microscopy Research and Technique · doi:10.1002/jemt.10064 · Cited by 36
Cognitive and behavioral correlates of caudate subregion shape variation in fragile X syndrome
Peng, D. X., Kelley, R. G., Quintin, E., Raman, M. M., Thompson, P. M., & Reiss, A. L. (2013) · Human Brain Mapping · doi:10.1002/hbm.22376 · Cited by 35
Triplet repeat disorders: discussion of molecular mechanisms
Timchenko, L., & Caskey, C. T. (1999) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050383 · Cited by 35
FMRP Interacts with C/D Box snoRNA in the Nucleus and Regulates Ribosomal RNA Methylation
D’Souza, M. N., Gowda, N. K. C., Tiwari, V., Babu, R. O., Anand, P., Dastidar, S. G., Singh, R., James, O. G., Selvaraj, B. T., Pal, R., et al. (2018) · iScience · doi:10.1016/j.isci.2018.11.007 · Cited by 34
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Sofola-Adesakin, O., Sundram, V., Ng, F., Kleyner, Y., Morales, J., Botas, J., Jackson, F. R., & Nelson, D. L. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2786-08.2008 · Cited by 34
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Bhogal, B., & Jongens, T. A. (2010) · Disease Models & Mechanisms · doi:10.1242/dmm.002006 · Cited by 36
Fragile X syndrome. Molecular and clinical insights and treatment issues.
Hagerman, R. J. (1997) · Europe PMC (PubMed Central) · Cited by 33
Transport kinetics of FMRP containing the I304N mutation of severe fragile X syndrome in neurites of living rat PC12 cells
Schrier, M., Severijnen, L., Reis, S. A., Rife, M. F., VANTPADJE, S., VANCAPPELLEN, G., Oostra, B. A., & Willemsen, R. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.05.039 · Cited by 34
From Learning to Memory: What Flies Can Tell Us about Intellectual Disability Treatment
Androschuk, A., Al-Jabri, B. A., & Bolduc, F. V. (2015) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00085 · Cited by 33
Quantitative Phosphoproteomics of MurineFmr1-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms
Matić, K., Eninger, T., Bardoni, B., Davidovic, L., & Maček, B. (2014) · Journal of Proteome Research · doi:10.1021/pr5006372 · Cited by 33
Molecular Insights into Mental Retardation: Multiple Functions for the Fragile X Mental Retardation Protein?
Zalfa, F., & Bagni, C. (2004) · Current Issues in Molecular Biology · doi:10.21775/cimb.006.073 · Cited by 33
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Rousseau, F., Labelle, Y., Bussières, J., & Lindsay, C. (2011) · Europe PMC (PubMed Central) · Cited by 30
Self-citation
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Heulens, I. (2010) · Frontiers in bioscience · doi:10.2741/3785 · Cited by 32
Nuclease sensitivity of permeabilized cells confirms altered chromatin formation at the fragile X locus
Eberhart, D. E., & Warren, S. T. (1996) · Somatic Cell and Molecular Genetics · doi:10.1007/bf02369435 · Cited by 31
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He, Q., & Ge, W. (2017) · Scientific Reports · doi:10.1038/s41598-017-01175-8 · Cited by 30
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Kurosaki, T., Mitsutomi, S., Hewko, A., Akimitsu, N., & Maquat, L. E. (2022) · Molecular Cell · doi:10.1016/j.molcel.2022.10.018 · Cited by 36
Tandem repeats in human disorders: mechanisms and evolution
Siwach, P. (2008) · Frontiers in bioscience · doi:10.2741/3017 · Cited by 29
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Till, S. M., Li, H.-L., Miniaci, M. C., Kandel, E. R., & Choi, Y. (2010) · Learning & Memory · doi:10.1101/lm.1958811 · Cited by 30
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[Expansion of trinucleotide repeats].
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Tan, Y., Sgobio, C., Arzberger, T., Machleid, F., Tang, Q., Findeis, E., Tost, J., Chakroun, T., Gao, P., Höllerhage, M., et al. (2019) · Acta Neuropathologica · doi:10.1007/s00401-019-02099-5 · Cited by 24
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Salat, U., Bardoni, B., Wöhrle, D., & Steinbach, P. (2000) · Journal of Medical Genetics · doi:10.1136/jmg.37.11.842 · Cited by 24
K Homology Domains of the Mouse Polycystic Kidney Disease-Related Protein, Bicaudal-C (Bicc1), Mediate RNA Binding in vitro
Bouvrette, D. J., Price, S. J., & Bryda, E. C. (2008) · Nephron Experimental Nephrology · doi:10.1159/000112913 · Cited by 23
Platelets as a surrogate disease model of neurodevelopmental disorders: Insights from Fragile X Syndrome
Pellerin, D., Lortie, A., & Corbin, F. (2017) · Platelets · doi:10.1080/09537104.2017.1317733 · Cited by 25
Self-citation
Fragile X syndrome and Friedreich’s ataxia: two different paradigms for repeat induced transcript insufficiency
Grabczyk, E., Kumari, D., & Usdin, K. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00572-x · Cited by 22
Animal Model for Fragile X Syndrome
Oostra, B. A., & Hoogeveen, A. T. (1997) · Annals of Medicine · doi:10.3109/07853899709007483 · Cited by 21
The Fragile X Syndrome and Other Fragile Site Disorders
Kooy, R. F., Oostra, B. A., & Willems, P. J. (1998) · Results and problems in cell differentiation · doi:10.1007/978-3-540-69680-3_1 · Cited by 22
The fragile X syndrome
Hoogeveen, A. T., & Oostra, B. A. (1997) · Journal of Inherited Metabolic Disease · doi:10.1023/a:1005392319533 · Cited by 23
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Cook, D., Nuro, E., & Murai, K. K. (2013) · Developmental Neurobiology · doi:10.1002/dneu.22096 · Cited by 22
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Guduric‐Fuchs, J., Möhrlen, F., Frohme, M., & Uri Frank, A. (2004) · Gene · doi:10.1016/j.gene.2004.10.007 · Cited by 19
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Hardiman, R. L., & Bratt, A. M. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.09.030 · Cited by 17
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Gülay, S. P., Bista, S., Varshney, A., Kırmızıaltın, S., Sanbonmatsu, K. Y., & Dinman, J. D. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx112 · Cited by 17
FMRP ribonucleoprotein complexes and RNA homeostasis
Suardi, G. A. M., & Haddad, L. A. (2020) · Advances in genetics · doi:10.1016/bs.adgen.2020.01.001 · Cited by 18
Identification of FMRP‐associated mRNAs using yeast three‐hybrid system
Zou, K., Liu, J., Zhu, N., Lin, J., Liang, Q., Brown, W. T., Shen, Y., & Zhong, N. A. (2007) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30678 · Cited by 17
Fragile X mental retardation protein in plasticity and disease
Todd, P. K., & Malter, J. S. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10453 · Cited by 17
Expansion of Trinucleotide Repeats
Siyanova, E. Y., & Mirkin, S. M. (2001) · Molecular Biology · doi:10.1023/a:1010431232481 · Cited by 17
FMRP binding to a ranked subset of long genes is revealed by coupled CLIP and TRAP in specific neuronal cell typesPreprint
Driesche, S. J. V., Sawicka, K., Zhang, C., Hung, K. Y. S., Park, C. Y., Fak, J. J., Yang, C., Darnell, R. B., & Darnell, J. C. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/762500 · Cited by 17
A non-canonical start codon in the Drosophila fragile X gene yields two functional isoforms
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Dynamic mutations in human genes: A review of trinucleotide repeat diseases
Longshore, J. W., & Tarleton, J. C. (1996) · Journal of Genetics · doi:10.1007/bf02931762 · Cited by 16
10 years' experience in fragile X testing among mentally retarded individuals in Greece: a molecular and epidemiological approach.
Sofocleous, C., Kitsiou, S., Fryssira, H., Kolialexi, A., Καλαϊτζιδάκη, Μ., Roma, E. S., Tsangaris, G. T., Chistofidou, C., Metaxotou, C., Kanavakis, E., et al. (2008) · PubMed · Cited by 14
Molecular Basis of Genetic Neuropsychiatric Disorders
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Self-citation
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Breast cancer genetics: Family history, heterogeneity, molecular genetic diagnosis, and genetic counseling
Lynch, H. T., & Lynch, J. F. (1996) · Current Problems in Cancer · doi:10.1016/s0147-0272(96)80010-9 · Cited by 10
Functions of the fragile X protein
Oostra, B. A. (2002) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(02)02271-2 · Cited by 9
FMR1 mutant marmosets show fragile X syndrome phenotypes
Harbers, M., Wei, Z., Nakao, H., Abe, Y., Goto, M., Tamano, M., Sakai, Y., Shimizu, K., Nakao, K., Sugaya, Y., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116208 · Cited by 9
Epitranscriptome marks detection and localization of RNA modifying proteins in mammalian ovarian follicles
Dubuc, K., Marchais, M., Gilbert, I., Bastien, A., Nenonene, E. K., Khandjian, E. W., Viger, R. S., Delbès, G., & Robert, C. (2023) · Journal of Ovarian Research · doi:10.1186/s13048-023-01172-8 · Cited by 7
Self-citation
Genetic Counseling for Fragile X Syndrome: Recommendations of the National Society of Genetic Counselors
McIntosh, N. M., Gane, L. W., McConkie‐Rosell, A., & Bennett, R. L. (2000) · Journal of Genetic Counseling · doi:10.1023/a:1009454112907 · Cited by 7
The role of brain-derived neurotrophic factor in neural circuit development and function
Autry, A. E., & Bambah-Mukku, D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-823672-7.00020-x · Cited by 6
Molecular medicine of fragile X syndrome: based on known molecular mechanisms
Luo, S.-Y., Wu, L., & Duan, R. (2015) · World Journal of Pediatrics · doi:10.1007/s12519-015-0052-0 · Cited by 8
Shared Cell Biological Functions May Underlie Pleiotropy of Molecular Interactions in the Germ Lines and Nervous Systems of Animals
Kulkarni, A., Lopez, D. H., & Extavour, C. G. M. (2020) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2020.00215 · Cited by 8
Molecular dynamics of FMRP and other RNA-binding proteins in MEG-01 differentiation: the role of mRNP complexes in non-neuronal development
McCoy, M., Poliquin-Duchesneau, D., & Corbin, F. (2016) · Biochemistry and Cell Biology · doi:10.1139/bcb-2015-0131 · Cited by 7
Self-citation
A Distinct FMRP Polysomal Population at an Advanced Stage of Mammalian Erythropoiesis
Beaulieu, M.-A. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3313 · Cited by 6
FMRP: a new chapter with chromatin
He, Q., & Ge, W. (2014) · Protein & Cell · doi:10.1007/s13238-014-0105-5 · Cited by 5
Genetics of Childhood Disorders: XI. Fragile X Syndrome
D, S. E. M., & Reiss, A. L. (2000) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200002000-00029 · Cited by 5
Focusing on mRNA Granules and Stalled Polysomes Amidst Diverse Mechanisms Underlying mRNA Transport, mRNA Storage, and Local Translation
Anadolu, M. N., & Sossin, W. S. (2020) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190686307.013.20 · Cited by 4
AGG interspersion analysis of the FMR1 CGG repeats in mental retardation of unspecific cause
Poon, P. M. K., Chen, Q. L., Zhong, N., Lam, S. T. S., Lai, K. Y. C., Wong, C. K., & Pang, C. (2005) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2005.11.005 · Cited by 4
Manipulating the Fragile X Mental Retardation Proteins in the Frog
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Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation
Eggan, K. C., & Jaenisch, R. (2003) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2003.09.012 · Cited by 3
Predicted interaction of human Ribosomal Protein S15 with Fragile X Mental Retardation Protein
Sim, E. U., Ma, X.-R., Li, S., Lee, C. W., & Narayanan, K. (2016) · Journal of Applied Biology & Biotechnology · doi:10.7324/jabb.2016.40206 · Cited by 3
The Fragile X Syndrome
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Fragile X-Linked Mental Retardation
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Authors: Khandjian, E. W., Corbin, F., Woerly, S., & Rousseau, F.
Affiliations: Hôpital Saint-François d'Assise (CA)
ORCID: Corbin, François
Rousseau, François
Venue: Nature Genetics
Publisher: Springer Science and Business Media LLC
Published: 1996-01
Volume: 12
Issue: 1
Pages: 91-93
ISSN: 1061-4036 (ISSN-L)
1546-1718
DOI: 10.1038/ng0196-91
OpenAlex: W2026456570
Cited by: 251
References: 30
Citations by year: 2026: 3 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 4 · 2021: 3 · 2020: 10 · 2019: 7 · 2018: 4 · 2017: 6 · 2016: 8 · 2015: 6 · 2014: 12 · 2013: 8 · 2012: 5
FWCI: 9.81
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Genetics (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
Keywords: FMRP, fragile X syndrome, ribosome association, 60S ribosomal subunit, CGG repeat expansion, FMR1 gene silencing, RNA-binding proteins, translation machinery, neurons, polysomes
MeSH terms: Animals, Cell Compartmentation, Fragile X Syndrome, HeLa Cells, Humans, Nerve Tissue Proteins, Protein Binding, Ribosomes, Protein Biosynthesis, 3T3 Cells, RNA-Binding Proteins, Fluorescent Antibody Technique, Indirect, Mice, Fragile X Messenger Ribonucleoprotein 1, Fragile X Mental Retardation Protein

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