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The fragile X mental retardation protein is associated with ribosomes

Khandjian, Edouard W., Corbin, François, Woerly, Stephane, Rousseau, François·1996·Nature Genetics

DOI 10.1038/ng0196-91

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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
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Authors: Khandjian, E. W., Corbin, F., Woerly, S., & Rousseau, F.
Affiliations: Hôpital Saint-François d'Assise (CA)
ORCID: Corbin, François
Rousseau, François
Venue: Nature Genetics
Publisher: Springer Science and Business Media LLC
Published: 1996-01
Volume: 12
Issue: 1
Pages: 91-93
ISSN: 1061-4036 (ISSN-L)
1546-1718
DOI: 10.1038/ng0196-91
OpenAlex: W2026456570
Cited by: 251
References: 30
Citations by year: 2026: 3 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 4 · 2021: 3 · 2020: 10 · 2019: 7 · 2018: 4 · 2017: 6 · 2016: 8 · 2015: 6 · 2014: 12 · 2013: 8 · 2012: 5
FWCI: 9.81
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Genetics (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
Keywords: FMRP, fragile X syndrome, ribosome association, 60S ribosomal subunit, CGG repeat expansion, FMR1 gene silencing, RNA-binding proteins, translation machinery, neurons, polysomes
MeSH terms: Animals, Cell Compartmentation, Fragile X Syndrome, HeLa Cells, Humans, Nerve Tissue Proteins, Protein Binding, Ribosomes, Protein Biosynthesis, 3T3 Cells, RNA-Binding Proteins, Fluorescent Antibody Technique, Indirect, Mice, Fragile X Messenger Ribonucleoprotein 1, Fragile X Mental Retardation Protein

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