The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Receptor-Mediated Pathway for Cholesterol Homeostasis
Brown, M. S., & Goldstein, J. L. (1986) · Science · doi:10.1126/science.3513311 · Cited by 5,703
Submucosal glands are the predominant site of CFTR expression in the human bronchus
Engelhardt, J. F., Yankaskas, J. R., Ernst, S. A., Yang, Y., Marino, C. R., Boucher, R. C., Cohn, J. A., & Wilson, J. M. (1992) · Nature Genetics · doi:10.1038/ng1192-240 · Cited by 653
Self-citationIncreased Expression of DNA Cointroduced with Nuclear Protein in Adult Rat Liver
Kaneda, Y., Iwai, K., & Uchida, T. (1989) · Science · doi:10.1126/science.2911748 · Cited by 454
Adenovirus–mediated in vivo gene transfer and expression in normal rat liver
Jaffe, H. A., Danel, C., Longenecker, G., Metzger, M., Setoguchi, Y., Rosenfeld, M. A., Gant, T. W., Thorgeirsson, S. S., Stratford-Perricaudet, L. D., Perricaudet, M., et al. (1992) · Nature Genetics · doi:10.1038/ng0892-372 · Cited by 449
Bilheimer, D. W., Goldstein, J. L., Grundy, S. M., Starzl, T. E., & Brown, M. S. (1984) · New England Journal of Medicine · doi:10.1056/nejm198412273112603 · Cited by 442
HEART-LIVER TRANSPLANTATION IN A PATIENT WITH FAMILIAL HYPERCHOLESTEROLAEMIA
Starzl, T. E., Bahnson, H. T., Hardesty, R. L., Iwatsuki, S., Gartner, J. C., Bilheimer, D. W., Shaw, B. W., Griffith, B. P., Zitelli, B. J., Malatack, J. J., et al. (1984) · The Lancet · doi:10.1016/s0140-6736(84)91876-2 · Cited by 375
Long-Term Improvement of Hypercholesterolemia After Ex Vivo Gene Therapy in LDLR-Deficient Rabbits
Chowdhury, J. R., Grossman, M., Gupta, S., Chowdhury, N. R., Baker, J. R., & Wilson, J. M. (1991) · Science · doi:10.1126/science.1722351 · Cited by 366
Self-citationCommon low-density lipoprotein receptor mutations in the French Canadian population.
Leitersdorf, E., Tobin, E. J., Davignon, J., & Hobbs, H. H. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114531 · Cited by 302
Wu, C. H., Wilson, J. M., & Wu, G. Y. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71447-6 · Cited by 287
Self-citationKay, M. A., Baley, P., Rothenberg, S., Leland, F., Fleming, L., Ponder, K. P., Liu, T., Finegold, M., Darlington, G., & Pokorny, W. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.1.89 · Cited by 245
Cited by
Overturf, K., Al-Dhalimy, M., Tanguay, R., Brantly, M., Ou, C.-N., Finegold, M., & Grompe, M. (1996) · Nature Genetics · doi:10.1038/ng0396-266 · Cited by 549
Transplantation of cells in matrices for tissue regeneration
Marler, J. J., Upton, J., Langer, R., & Vacanti, J. P. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(98)00025-8 · Cited by 377
Hepatocyte Transplantation for the Treatment of Human Disease
Strom, S., Chowdhury, J., & Fox, I. (1999) · Seminars in Liver Disease · doi:10.1055/s-2007-1007096 · Cited by 366
Gene therapy for lipoprotein lipase deficiency
Gaudet, D., Méthot, J., & Kastelein, J. (2012) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283555a7e · Cited by 178
Longo, C. R., Patel, V. I., Shrikhande, G. V., Scali, S. T., Csizmadia, E., Daniel, S., Sun, D. W., Grey, S. T., Arvelo, M. B., & Ferran, C. (2005) · Hepatology · doi:10.1002/hep.20741 · Cited by 60
Metadata
- Authors
- Grossman, M., Raper, S. E., Kozarsky, K., Stein, E. A., Engelhardt, J. F., Muller, D., Lupien, P. J., & Wilson, J. M.
- Venue
- Nature Genetics
- Published
- 1994-04
- Volume
- 6
- Issue
- 4
- Pages
- 335-341
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2166797660
- Cited by
- 559
- References
- 12
- FWCI
- 36.55
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. https://app.cochat.ai/papers/10.1038/ng0494-335
- The paper
- Grossman, M., Raper, S. E., Kozarsky, K., Stein, E. A., Engelhardt, J. F., Muller, D., Lupien, P. J., & Wilson, J. M. (1994). Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. Nature Genetics. https://doi.org/10.1038/ng0494-335
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
