Characterizing DNA methylation alterations from The Cancer Genome Atlas

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

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Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

Huertas-Martínez, J., Rello‐Varona, S., Herrero‐Martín, D., Barrau, I., García-Monclús, S., Sáinz‐Jaspeado, M., Lagares‐Tena, L., Núñez‐Álvarez, Y., Mateo‐Lozano, S., Mora, J., et al. (2014) · Oncotarget · doi:10.18632/oncotarget.2403 · Cited by 23 · see citing works

Clinical applications and perspectives of circulating tumor DNA in gastric cancer

Li, J. M., Zhang, D., Zhu, J., & Dong, L. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03209-4 · Cited by 24 · see citing works

DNA methylation differentially regulates cytokine secretion in gingival epithelia in response to bacterial challenges

Drury, J. L., & Chung, W. O. (2014) · Pathogens and Disease · doi:10.1093/femspd/ftu005 · Cited by 23 · see citing works

Impact of DNA methylation programming on normal and pre-leukemic hematopoiesis

Langstein, J., Milsom, M. D., & Lipka, D. B. (2017) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2017.09.008 · Cited by 23 · see citing works

Epigenetic heterogeneity affects the risk of relapse in children with t(8;21)RUNX1-RUNX1T1-rearranged AML

Zampini, M., Tregnago, C., Bisio, V., Simula, L., Borella, G., Manara, E., Zanon, C., Zonta, F., Serafin, V., Accordi, B., et al. (2018) · Leukemia · doi:10.1038/s41375-017-0003-y · Cited by 23 · see citing works

SOX14 hypermethylation as a tumour biomarker in cervical cancer

Zhao, J. T., Cao, H., Zhang, W., Yongjuan, F., Shi, S., & Wang, R. (2021) · BMC Cancer · doi:10.1186/s12885-021-08406-2 · Cited by 22 · see citing works

Detection of methylated BCAT1 and IKZF1 after curative‐intent treatment as a prognostic indicator for colorectal cancer recurrence

Pedersen, S. K., Symonds, E. L., Roy, A. C., Cornthwaite, K. J., LaPointe, L. C., & Young, G. P. (2022) · Cancer Medicine · doi:10.1002/cam4.5008 · Cited by 21 · see citing works

Layered genetic control of DNA methylation and gene expression: a locus of multiple sclerosis in healthy individuals

Shin, J., Bourdon, C., Bernard, M., Wilson, M. D., Reischl, E., Waldenberger, M., Ruggeri, B., Schumann, G., Desrivières, S., Leemans, A., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv294 · Cited by 20 · see citing works

Pancreatic cancer heterogeneity and response to Mek inhibition

Pedersen, K., Bilal, F., Morales, C. B., Salcedo, M., Macarulla, T. M., Massó-Vallés, D., Mohan, V., Vivancos, A. P., Carreras, M.-J., Serres, X., et al. (2017) · Oncogene · doi:10.1038/onc.2017.174 · Cited by 22 · see citing works

Multiomics analysis reveals CT83 is the most specific gene for triple negative breast cancer and its hypomethylation is oncogenic in breast cancer

Chen, C., Gao, D., Huo, J., Qu, R., Guo, Y., Hu, X., & Luo, L. (2021) · Scientific Reports · doi:10.1038/s41598-021-91290-4 · Cited by 22 · see citing works

DNA methylation-based classification and identification of bladder cancer prognosis-associated subgroups

Tian, Z., Meng, L., Long, X., Diao, T., Hu, M., Wang, M., Liu, M., & Wang, J. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01345-1 · Cited by 21 · see citing works

Identification of four differentially methylated genes as prognostic signatures for stage I lung adenocarcinoma

Luo, W., Wang, Z., & Zhang, X. (2018) · Cancer Cell International · doi:10.1186/s12935-018-0547-6 · Cited by 21 · see citing works

Pan-Cancer Analysis Reveals Presence of Pronounced DNA Methylation Drift In Cpg Island Methylator Phenotype Clusters

Karpiński, P., Pesz, K. A., & Sasiadek, M. M. (2017) · Epigenomics · doi:10.2217/epi-2017-0070 · Cited by 20 · see citing works

Detection of recurrent colorectal cancer with high specificity using a reporting threshold for circulating tumor DNA methylated in BCAT1 and IKZF1

Pedersen, S. K., Musher, B., LaPointe, L. C., Tuck, M. K., Symonds, E. L., Loayza, N., & Young, G. P. (2022) · Cancer · doi:10.1002/cncr.34159 · Cited by 19 · see citing works

Screening and identification of biomarkers associated with the diagnosis and prognosis of lung adenocarcinoma

Wang, Y., Zhang, L., Chen, Y., Li, M., Min-wen, H., & Li, S. (2020) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.23450 · Cited by 19 · see citing works

Aberrant methylation patterns in colorectal cancer: a meta-analysis

Durso, D. F., Bacalini, M. G., do Valle, Í. F., Pirazzini, C., Bonafè, M., Castellani, G., Faria, A. M. C., Franceschi, C., Garagnani, P., & Nardini, C. (2017) · Oncotarget · doi:10.18632/oncotarget.14590 · Cited by 19 · see citing works

Evaluation of a plasma cell-free DNA methylation test for colorectal cancer diagnosis: a multicenter clinical study

Wang, Z., He, Z., Lin, R., Feng, Z., Li, X., Sui, X., Gu, L., Xia, T., Zhou, D., Zhao, B., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03662-y · Cited by 19 · see citing works

Comprehensive Bioinformatic Investigation of TP53 Dysregulation in Diverse Cancer Landscapes

Khan, R., Puszyński, K., & Kozłowska, E. (2024) · Genes · doi:10.3390/genes15050577 · Cited by 18 · see citing works

Clinical Genomics: Challenges and Opportunities

Vijay, P., McIntyre, A. B. R., Mason, C. E., Greenfield, J. P., & Li, S. (2016) · Critical Reviews in Eukaryotic Gene Expression · doi:10.1615/critreveukaryotgeneexpr.2016015724 · Cited by 18 · see citing works

Validation of a Circulating Tumor-Derived DNA Blood Test for Detection of Methylated BCAT1 and IKZF1 DNA

Murray, D. H., Baker, R. T., Gaur, S., Young, G. P., & Pedersen, S. K. (2017) · The Journal of Applied Laboratory Medicine · doi:10.1373/jalm.2017.023135 · Cited by 19 · see citing works

Analysis of methylation microarray for tissue specific detection

Muangsub, T., Samsuwan, J., Tongyoo, P., Kitkumthorn, N., & Mutirangura, A. (2014) · Gene · doi:10.1016/j.gene.2014.09.060 · Cited by 17 · see citing works

Compartmentation of Metabolites in Regulating Epigenomes of Cancer

Zhao, Z., Wang, L., & Di, L. (2016) · Molecular Medicine · doi:10.2119/molmed.2016.00051 · Cited by 17 · see citing works

Great expectations – Epigenetics and the meandering path from bench to bedside

Häfner, S. J., & Lund, A. (2016) · Biomedical Journal · doi:10.1016/j.bj.2016.01.008 · Cited by 17 · see citing works

Decoding the complexity: mechanistic insights into comorbidities in idiopathic pulmonary fibrosis

Selman, M., Buendia-Roldan, I., & Pardo, A. (2025) · European Respiratory Journal · doi:10.1183/13993003.02418-2024 · Cited by 16 · see citing works

MethyCancer: the database of human DNA methylation and cancer

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MethHC: a database of DNA methylation and gene expression in human cancer

Huang, W.-Y., Hsu, S., Huang, H., Sun, Y.-M., Chou, C., Weng, S.-L., & Huang, H. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1151 · Cited by 296 · see citing works

A Review of the Methods for Detecting and Characterizing DNA Methylation as a Cancer Biomark

El-Booz, S. A., Radad, M. A., El-Fishawy, N. A., & Attiya, G. (2019) · Menoufia Journal of Electronic Engineering Research · doi:10.21608/mjeer.2019.69025

Aberrant DNA methylation in cancer: potential clinical interventions

Strathdee, G. R., & Brown, R. E. (2002) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399402004222 · Cited by 101 · see citing works

Cytosine methylation profiling of cancer cell lines

Ehrich, M., Turner, J., Gibbs, P., Lipton, L. R., Giovanneti, M., Cantor, C. R., & van den Boom, D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712251105 · Cited by 133 · see citing works