A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

Cited by (999)

Items 201–300 of 999

  1. Identification of Driver and Passenger DNA Methylation in Cancer by Epigenomic Analysis
    Satish K. Kalari, Gerd P. Pfeifer · 2010 · Advances in genetics
  2. Abnormal DNA Methylation of CD133 in Colorectal and Glioblastoma Tumors
    Joo Mi Yi, Hsing-Chen Tsai, Sabine C. Glöckner, Steven Hsesheng Lin, Joyce Ellen Ohm, Hariharan Easwaran, Charles David James, J Costello, Gregory Joseph Riggins, Charles G. Eberhart et al. · 2008 · Cancer Research
  3. Minireview: Epigenetic Alterations in Human Prostate Cancers
    William G. Nelson, Angelo Michael De Marzo, Srinivasan Yegnasubramanian · 2009 · Endocrinology
  4. Analysis of Promoter CpG Island Hypermethylation in Cancer: Location, Location, Location!
    Iris J.H. van Vlodrop, Hanneke E.C. Niessen, Sarah Derks, Marcella M.L.L. Baldewijns, Wim Van Criekinge, James Gordon Herman, Manon van Engeland · 2011 · Clinical Cancer Research
  5. Editing the Epigenome: Reshaping the Genomic Landscape
    Liad Holtzman, Charles A. Gersbach · 2018 · Annual Review of Genomics and Human Genetics
  6. Methylation across the central dogma in health and diseases: new therapeutic strategies
    Ruochen Liu, Erhu Zhao, Huijuan Yu, Chaoyu Yuan, Muhammad Nadeem Abbas, Hongjuan Cui · 2023 · Signal Transduction and Targeted Therapy
  7. Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic protein pathway
    Liudmila L. Kodach, Rutger J. Jacobs, Philip W. Voorneveld, Manon E. Wildenberg, Henricus W Verspaget, Tom van Wezel, Hans M. Morreau, Daniël W. Hommes, Maikel Petrus Peppelenbosch, Gijs R. VAN DEN BRINK et al. · 2011 · Gut
  8. Epigenetic Repression of p16INK4A by Latent Epstein-Barr Virus Requires the Interaction of EBNA3A and EBNA3C with CtBP
    Lenka Skalska, Robert E. White, Melanie Franz, Michaela Ruhmann, Martin J. Allday · 2010 · PLoS Pathogens
  9. Epigenetic changes in healthy human skeletal muscle following exercise– a systematic review
    Macsue Jacques, Danielle Hiam, Jeffrey Mark Craig, Romain Barrès, Nir Eynon, Sarah Amandine Caroline Voisin · 2019 · Epigenetics
  10. Epithelial Progeny of Estrogen-Exposed Breast Progenitor Cells Display a Cancer-like Methylome
    Alfred S.L. Cheng, Aedín C. Culhane, Michael W.Y. Chan, Chinnambally R. Venkataramu, Mathias Ehrich, Aejaz Nasir, Benjamin A.T. Rodriguez, Joseph Liu, Pearlly S. Yan, John F Quackenbush et al. · 2008 · Cancer Research
  11. Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2
    Daisy P. Tsang, Alfred S.L. Cheng · 2010 · Journal of Gastroenterology and Hepatology
  12. DNA methylation aberrancies as a guide for surveillance and treatment of human cancers
    Gangning Liang, Daniel J. Weisenberger · 2017 · Epigenetics
  13. Decoding the function of bivalent chromatin in development and cancer
    Dhirendra Kumar, Senthilkumar Cinghu, Andrew Oldfield, Pengyi Yang, Raja Jothi · 2021 · Genome Research
  14. Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming
    Xiao Zhang, F D Cruz, Mary Beth Terry, Fabrizio Remotti, Igor Matushansky · 2012 · Oncogene
  15. Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains
    Trowbridge, Jennifer J., Sinha, Amit U., Zhu, Nan, Li, Mingjie, Armstrong, Scott A., Orkin, Stuart H. · 2012 · Genes & Development
  16. CpG Island Hypermethylation in Human Astrocytomas
    Xiwei Wu, Tibor A. Rauch, Xueyan Zhong, William P. Bennett, Farida Latif, Dietmar Krex, Gerd P. Pfeifer · 2010 · Cancer Research
  17. Detection of Long Non-Coding RNA in Archival Tissue: Correlation with Polycomb Protein Expression in Primary and Metastatic Breast Carcinoma
    Karen M. Chisholm, Yue Wan, Rui Li, Kelli D. Montgomery, Howard Y. Chang, Robert B. West · 2012 · PLoS ONE
  18. LSH Cooperates with DNA Methyltransferases To Repress Transcription
    Kevin Myant, Irina Stancheva · 2007 · Molecular and Cellular Biology
  19. CpG island methylator phenotype (CIMP) in cancer: Causes and implications
    Jens M. Teodoridis, Catriona Hardie, Robert Eldon Brown · 2008 · Cancer Letters
  20. The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands
    Hideyuki Takeshima, Satoshi Yamashita, Taichi Shimazu, Tohru Niwa, Toshikazu Ushijima · 2009 · Genome Research
  21. A Comprehensive Microarray-Based DNA Methylation Study of 367 Hematological Neoplasms
    Martin-Subero, Jose I., Ammerpohl, Ole, Bibikova, Marina, Wickham-Garcia, Eliza, Agirre, Xabier, Alvarez, Sara, Brüggemann, Monika, Bug, Stefanie, Calasanz, Maria J., Deckert, Martina et al. · 2009 · PLoS ONE
  22. Mutator pathways unleashed by epigenetic silencing in human cancer
    Filipe V. Jacinto, Manel Esteller · 2007 · Mutagenesis
  23. Genomic insights into cancer-associated aberrant CpG island hypermethylation
    Duncan Sproul, Richard R. Meehan · 2013 · Briefings in Functional Genomics
  24. Defining a Chromatin Pattern that Characterizes DNA-Hypermethylated Genes in Colon Cancer Cells
    Kelly M. McGarvey, Leander Van Neste, Leslie Cope, Joyce Ellen Ohm, James Gordon Herman, Wim Van Criekinge, Kornel E. Schuebel, Stephen B. Baylin · 2008 · Cancer Research
  25. Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma
    Matthias Lechner, Tim R. Fenton, James West, Gareth A. Wilson, Andrew Feber, Stephen R Henderson, Christina Thirlwell, Harpreet K. Dibra, Amrita Jay, Lee M Butcher et al. · 2013 · Genome Medicine
  26. Genome-wide age-related DNA methylation changes in blood and other tissues relate to histone modification, expression and cancer
    Zongli Xu, Jack A. Taylor · 2013 · Carcinogenesis
  27. Combination therapy with epigenetic-targeted and chemotherapeutic drugs delivered by nanoparticles to enhance the chemotherapy response and overcome resistance by breast cancer stem cells
    Shi-Yong Li, Rong Sun, Hongxia Wang, Song Shen, Yang Liu, Xiao‐Jiao Du, Yanhua Zhu, Wang Jun · 2014 · Journal of Controlled Release
  28. Homeobox oncogene activation by pan-cancer DNA hypermethylation
    Jianzhong Su, Yung‐Hsin Huang, Xiaodong Cui, Xinyu Wang, Xiaotian Zhang, Yong Lei, Jianfeng Xu, Xueqiu Lin, Kaifu Chen, Jie Lv et al. · 2018 · Genome biology
  29. Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer
    Stephan H. Bernhart, Helene Kretzmer, Lesca Miriam Holdt, Frank Jühling, Ole Ammerpohl, Anke Katharina Bergmann, Bernd H. Northoff, Gero Doose, Reiner Siebert, Peter Florian Stadler et al. · 2016 · Scientific Reports
  30. miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer
    Lukáš Vrba, José L. Muñoz-Rodríguez, Martha R. Stampfer, Bernard W. Futscher · 2013 · PLoS ONE
  31. Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling
    Anne‐Marie Martinez, Bernd Schuettengruber, Samy Sakr, Ana Janic, Cayetano González, Giacomo Cavalli · 2009 · Nature Genetics
  32. The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae
    Takeshi Nakajima, Satoshi Yamashita, Takao Maekita, Tohru Niwa, Kazuyuki Nakazawa, Toshikazu Ushijima · 2008 · International Journal of Cancer
  33. A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations
    Vijay Kumar Tiwari, Leslie Cope, Kelly M. McGarvey, Joyce Ellen Ohm, Stephen B. Baylin · 2008 · Genome Research
  34. Targeting EZH2 and PRC2 dependence as novel anticancer therapy
    Bowen Xu, Kyle D. Konze, Jian Jun Jin, Gang Greg Wang · 2015 · Experimental Hematology
  35. Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas
    Wentao Gao, Yutaka Kondo, Lanlan Shen, Yasuhiro Shimizu, Tsuyoshi Sano, Kenji Yamao, Atsushi Natsume, Yasuhiro Gotô, Motokazu Ito, Hideki Murakami et al. · 2008 · Carcinogenesis
  36. Coordinate Regulation of DNA Methylation and H3K27me3 in Mouse Embryonic Stem Cells
    James A. Hagarman, Michael P. Motley, Katla Kristjánsdóttir, Paul D. Soloway · 2013 · PLoS ONE
  37. Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung
    Julien D. F. Licchesi, William H. Westra, Craig M. Hooker, Emi Ota Machida, Stephen B. Baylin, James Gordon Herman · 2008 · Carcinogenesis
  38. DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk
    Xie, Wenbing, Kagiampakis, Ioannis, Pan, Lixia, Zhang, Yang W., Murphy, Lauren, Tao, Yong, Kong, Xiangqian, Kang, Byunghak, Xia, Limin, Carvalho, Filipe L.F. et al. · 2018 · Cancer Cell
  39. Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells
    Jairo Rodríguez, Mar Muñoz, Laura Vives, Costakis G. Frangou, Mark T. Groudine, Miguel Angel Peinado · 2008 · Proceedings of the National Academy of Sciences
  40. CD133: to be or not to be, is this the real question?
    Elena Irollo, Giuseppe Pirozzi · 2013 · Europe PMC (PubMed Central)
  41. DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes
    Eriko G. Clements, Helai P. Mohammad, Benjamin R. Leadem, Hariharan Easwaran, Yi Cai, Leander Van Neste, Stephen B. Baylin · 2012 · Nucleic Acids Research
  42. DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers
    Ching-Yu Yen, Hurng‐Wern Huang, Chih‐Wen Shu, Ming‐Feng Hou, Shyng‐Shiou F. Yuan, Hui-Ru Wang, Yung-Ting Chang, Ammad Ahmad Farooqı, Jen‐Yang Tang, Hsueh‐Wei Chang · 2016 · Cancer Letters
  43. Genome‐wide DNA methylation profiles in precancerous conditions and cancers
    Yae Kanai · 2009 · Cancer Science
  44. DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns
    Ksenia Skvortsova, Etienne Masle‐Farquhar, Phuc‐Loi Luu, Jenny Z. Song, Wenjia Qu, Elena Zotenko, Cathryn M. Gould, Qian Du, Timothy J. Peters, Yolanda Colino‐Sanguino et al. · 2019 · Cancer Cell
  45. DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse
    Wanding Zhou, Toshinori Hinoue, Bret Barnes, Owen D. Mitchell, Waleed Iqbal, Sol Moe Lee, Kelly K. Foy, Kwang‐Ho Lee, Ethan Jacob Moyer, Alexandra VanderArk et al. · 2022 · Cell Genomics
  46. Promoter DNA Hypermethylation and Gene Repression in Undifferentiated Arabidopsis Cells
    María Berdasco, Rubén Alcázar, Maria Victoria García‐Ortiz, Esteban Ballestar, Agustín F. Fernández, Teresa Roldán‐Arjona, Antonio F. Tiburcio, Teresa Altabella, Nicolas Buisine, Hadi Quesneville et al. · 2008 · PLoS ONE
  47. Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions
    Andrew Erich Teschendorff, Martin Widschwendter · 2012 · Bioinformatics
  48. Induction of cells with cancer stem cell properties from nontumorigenic human mammary epithelial cells by defined reprogramming factors
    Mayuko Nishi, Yasuyuki Sakai, Hideo Akutsu, Yoji Nagashima, Gary Quinn, Shinji Masui, Hirokazu Kimura, Kilian Perrem, Akihiro Umezawa, Naoki Yamamoto et al. · 2013 · Oncogene
  49. A histone demethylase is necessary for regeneration in zebrafish
    Scott Stewart, Zhi-Yang Tsun, Juan Carlos Izpisúa Belmonte · 2009 · Proceedings of the National Academy of Sciences
  50. Epigenetic Drift, Epigenetic Clocks and Cancer Risk
    Shijie Zheng, Martin Widschwendter, Andrew Erich Teschendorff · 2016 · Epigenomics
  51. DNA methylation patterns in lung carcinomas
    Gerd P. Pfeifer, Tibor A. Rauch · 2009 · Seminars in Cancer Biology
  52. Epigenetics and cancer
    Rajnee Kanwal, Sanjay Gupta · 2010 · Journal of Applied Physiology
  53. Aberrant DNA methylation in contrast with mutations
    Toshikazu Ushijima, Kiyoshi Asada · 2009 · Cancer Science
  54. Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis
    Susan J. Clark · 2007 · Human Molecular Genetics
  55. The role of 5-hydroxymethylcytosine in human cancer
    Gerd P. Pfeifer, Wenying Xiong, Maria A. Hahn, Seung‐Gi Jin · 2014 · Cell and Tissue Research
  56. Polycomb-mediated silencing in neuroendocrine prostate cancer
    Pier‐Luc Clermont, Dong Lin, Francesco Crea, Rebecca Chung‐Fern Wu, Hui Xue, Yuwei Wang, Kelsie L. Thu, Wan L. Lam, Colin C. Collins, Yuzhuo Z. Wang et al. · 2015 · Clinical Epigenetics
  57. The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer
    Joanna J. Zhuang, Allison Jones, Shih‐Han Lee, Esther Ng, Heidi Fiegl, Michal Zikán, David Cibula, Alexandra Sargent, Helga Birgitte Salvesen, Ian J. Jacobs et al. · 2012 · PLoS Genetics
  58. Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment
    Olivia Alder, Fabrice Lavial, Anne Helness, Emily Brookes, Sandra Pinho, Anil Chandrashekran, Philippe Arnaúd, Ana Pombo, Laura P. O’Neill, Véronique Azuara · 2010 · Development
  59. DNMT1 and DNMT3B Modulate Distinct Polycomb-Mediated Histone Modifications in Colon Cancer
    Bilian Jin, Bing Yao, Jian‐Liang Li, C. Robert Fields, Amber L. Delmas, Chen Liu, Keith D. Robertson · 2009 · Cancer Research
  60. A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation
    Patrick T. Griffin, Chad E. Niederhuth, Robert J. Schmitz · 2016 · G3 Genes Genomes Genetics
  61. DNA Methylation and Complete Transcriptional Silencing of Cancer Genes Persist after Depletion of EZH2
    Kelly M. McGarvey, Eriko Greene, Jill A. Fahrner, Thomas Jenuwein, Stephen B. Baylin · 2007 · Cancer Research
  62. BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A
    Julian Puppe, Rinske Drost, Xiaoling Liu, Simon Andreas Joosse, Bastiaan Evers, Paulien Cornelissen‐Steijger, Petra M. Nederlof, Qiang Yu, Jos Jonkers, Maarten van Lohuizen et al. · 2009 · Breast Cancer Research
  63. BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV
    Kostas Paschos, Gillian A. Parker, Ekularn Watanatanasup, Robert E. White, Martin J. Allday · 2012 · Nucleic Acids Research
  64. DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer
    Varun Sasidharan Nair, Salman M. Toor, Rowaida Ziad Taha, Hibah Shaath, Eyad Elkord · 2018 · Clinical Epigenetics
  65. EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data
    Andrew Erich Teschendorff, Tianyu Zhu, Charles E. Breeze, Stephan Beck · 2020 · Genome biology
  66. Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
    Antonio Herrera-Merchan, Lorena Arranz, Jose Manuel Ligos, Antonio de Molina-Iracheta, Orlando Domı́nguez, Susana González · 2012 · Nature Communications · Retracted
  67. Epigenetic Priming in Cancer Initiation
    Carolina Vicente‐Dueñas, Julia Hauer, César Cobaleda, Arndt Borkhardt, Isidro Sánchez-Garcı́a · 2018 · Trends in cancer
  68. The role of DNA methylation in directing the functional organization of the cancer epigenome
    Fides D. Lay, Yaping Liu, Theresa Kathleen Kelly, Heather N. Witt, Peggy Farnham, Peter A. Jones, Benjamin P. Berman · 2015 · Genome Research
  69. Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma
    Kimberly J. Briggs, Ian M. Corcoran-Schwartz, Wei Zhang, Thomas Harcke, Wendy L. Devereux, Stephen B. Baylin, Charles G. Eberhart, D. Neil Watkins · 2008 · Genes & Development
  70. Concepts of epigenetics in prostate cancer development
    Christopher S. Cooper, Christopher S. Foster · 2008 · British Journal of Cancer
  71. The dynamic epigenetic program in male germ cells: Its role in spermatogenesis, testis cancer, and its response to the environment
    Maren Godmann, Romain Lambrot, Sarah Kimmins · 2009 · Microscopy Research and Technique
  72. Genome-Wide DNA Methylation as an Epigenetic Consequence of Epstein-Barr Virus Infection of Immortalized Keratinocytes
    Christine E. Birdwell, Krista J. Queen, Phillip C. S. R. Kilgore, Phoebe A. Rollyson, Marjan Trutschl, Urška Cvek, Rona S. Scott · 2014 · Journal of Virology
  73. Altered Histone Modifications in Gliomas
    Young Zoon Kim · 2014 · Brain Tumor Research and Treatment
  74. Retraction Note: Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
    Antonio Herrera-Merchan, Lorena Arranz, Jose Manuel Ligos, Antonio de Molina-Iracheta, Orlando Domı́nguez, Susana González · 2017 · Nature Communications · Retracted
  75. Epigenetic regulation of hepatocellular carcinoma in non-alcoholic fatty liver disease
    Yuan Tian, Vincent Wai‐Sun Wong, Henry Lik‐Yuen Chan, Alfred S.L. Cheng · 2013 · Seminars in Cancer Biology
  76. Genome-wide Analysis of CpG Island Methylation in Bladder Cancer Identified TBX2, TBX3, GATA2, and ZIC4 as pTa-Specific Prognostic Markers
    Raju Kandimalla, Angela A.G. van Tilborg, Lucie C. Kompier, Dominique J. P. M. Stumpel, Ronald W. Stam, Chris H. Bangma, Ellen C. Zwarthoff · 2012 · European Urology
  77. EZH2: Not EZHY (Easy) to Deal
    Gauri Deb, Anup Kumar Singh, Sanjay Gupta · 2014 · Molecular Cancer Research
  78. Implications of DNA Methylation in Parkinson’s Disease
    Ernesto G. Miranda-Morales, Karin Meier, Ada Agustina Sandoval-Carrillo, Jose Manuel Salas-Pacheco, Paola Vázquez-Cárdenas, Óscar Arias-Carrión · 2017 · Frontiers in Molecular Neuroscience
  79. The context and potential of epigenetics in oncology
    Juanita Suzanne Lopez, Michelle Percharde, Helen M. Coley, A Webb, Tim Crook · 2009 · British Journal of Cancer
  80. Global Promoter Methylation Analysis Reveals Novel Candidate Tumor Suppressor Genes in Natural Killer Cell Lymphoma
    Can Küçük, Xiaozhou Hu, Bei Jiang, David L. Klinkebiel, Huimin Geng, Qiang Gong, Alyssa C. Bouska, Javeed Iqbal, Philippe Gaulard, Timothy W. McKeithan et al. · 2015 · Clinical Cancer Research
  81. HOXA11 DNA methylation—A novel prognostic biomarker in ovarian cancer
    Heidi Fiegl, Gudrun H. Windbichler, Elisabeth Mueller‐Holzner, Georg Goebel, Matthias Lechner, Ian J. Jacobs, Martin Widschwendter · 2008 · International Journal of Cancer
  82. The role of aberrant DNA methylation in cancer initiation and clinical impacts
    Franziska Geissler, Ksenija Nesic, Olga Kondrashova, Alexander Dobrovic, Elizabeth M. Swisher, Clare L. Scott, Matthew J. Wakefield · 2024 · Therapeutic Advances in Medical Oncology
  83. Chronic Inflammation Induces a Novel Epigenetic Program That Is Conserved in Intestinal Adenomas and in Colorectal Cancer
    Monther Abu-Remaileh, Sebastian Bender, Günter Raddatz, Ihab Ansari, Daphne Cohen, Julian Gutekunst, Tanja Musch, Heinz Linhart, Achim Breiling, Eli Pikarsky et al. · 2015 · Cancer Research
  84. TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition
    Aurélie Morin, Judith Goncalves, Sophie Moog, Luis Jaime Castro‐Vega, Sylvie Job, Alexandre Buffet, Marie‐Joséphine Fontenille, Justine Woszczyk, Anne‐Paule Gimenez‐Roqueplo, Éric Letouzé et al. · 2020 · Cell Reports
  85. Histone Modifications in Cancer Biology and Prognosis
    Siavash K. Kurdistani · 2010 · Springer eBooks
  86. Stem Cell Chromatin Patterns: An Instructive Mechanism for DNA Hypermethylation?
    Joyce Ellen Ohm, Stephen B. Baylin · 2007 · Cell Cycle
  87. Linking DNA Methyltransferases to Epigenetic Marks and Nucleosome Structure Genome-wide in Human Tumor Cells
    Bilian Jin, Jason Ernst, Rochelle L. Tiedemann, Hongyan Xu, Suhas Sureshchandra, M Kellis, Stephen Dalton, Chen Liu, Jeong-Hyeon Choi, Keith D. Robertson · 2012 · Cell Reports
  88. Sirt1 Regulates DNA Methylation and Differentiation Potential of Embryonic Stem Cells by Antagonizing Dnmt3l
    Jinbeom Heo, Jisun Lim, Seungun Lee, Jaeho Jeong, Hyun-Sook Kang, Yong Hwan Kim, Jeong Wook Kang, Hwan Yeul Yu, Eui Man Jeong, Kyunggon Kim et al. · 2017 · Cell Reports
  89. Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands
    Daniel N. Weinberg, Phillip Rosenbaum, Xiao Chen, Douglas Barrows, Cynthia Horth, Matthew R. Marunde, Irina K Popova, Zachary B Gillespie, Michael‐Christopher Keogh, Chao Lü et al. · 2021 · Nature Genetics
  90. Breast cancer epigenetics: normal human mammary epithelial cells as a model system
    Rebecca A. Hinshelwood, Susan J. Clark · 2008 · Journal of Molecular Medicine
  91. An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells
    Karolina Holm, Johan Staaf, Martin Lauss, Mattias Aine, David Lindgren, Pär‐Ola Bendahl, Johan Vallon‐Christersson, Rosa Bjork Barkardottir, Mattias Höglund, Åke Borg et al. · 2016 · Breast Cancer Research
  92. The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome
    Martí Duran‐Ferrer, Guillem Clot, Ferran Nadeu, Renée Beekman, Tycho Baumann, Jessica Nordlund, Yanara Marincevic-Zuniga, Gudmar Lönnerholm, Alfredo Rivas‐Delgado, Silvia Martín et al. · 2020 · Nature Cancer
  93. Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas
    Xin Hu, Marcos R. Estecio, Runzhe Chen, Alexandre Reuben, Linghua Wang, Junya Fujimoto, Jian Carrot‐Zhang, Nicholas McGranahan, Lisha Ying, Junya Fukuoka et al. · 2021 · Nature Communications
  94. Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma
    Ole Ammerpohl, Johann Pratschke, Clemens Schafmayer, Andrea Haake, Wladimir Faber, Oliver von Kampen, Mario Brosch, Bence Sipos, Witigo V Schönfels, Katharina Balschun et al. · 2011 · International Journal of Cancer
  95. Poised chromatin in the mammalian germ line
    Bluma J. Lesch, David C. Page · 2014 · Development
  96. Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer
    Li Zhang, Lisheng Deng, Fengju Chen, Yuan Yao, Bulan Wu, Liping Wei, Qianxing Mo, Yongcheng Song · 2014 · Oncotarget
  97. Targeted Methylation of Two Tumor Suppressor Genes Is Sufficient to Transform Mesenchymal Stem Cells into Cancer Stem/Initiating Cells
    I-Wen Teng, Pei‐Chi Hou, Kuan‐Der Lee, Pei‐Yi Chu, Kun‐Tu Yeh, Victor X. Jin, Min‐Jen Tseng, Shaw‐Jenq Tsai, Yu‐Sun Chang, Chi‐Sheng Wu et al. · 2011 · Cancer Research
  98. DNMT3A R882 mutants interact with polycomb proteins to block haematopoietic stem and leukaemic cell differentiation
    Junji Koya, Keisuke Kataoka, Tomohiko Sato, Masashige Bando, Yuki Kato, Takako Tsuruta-Kishino, Hiroshi Kobayashi, Kensuke Narukawa, Hiroyuki Miyoshi, Katsuhiko Shirahige et al. · 2016 · Nature Communications
  99. Distinct chromatin signatures of DNA hypomethylation in aging and cancer
    Raúl F. Pérez, Juan Ramón Tejedor, Gustavo F. Bayón, Agustín F. Fernández, Mario F. Fraga · 2018 · Aging Cell
  100. Genomic Deregulation of the E2F/Rb Pathway Leads to Activation of the Oncogene EZH2 in Small Cell Lung Cancer
    Bradley P. Coe, Kelsie L. Thu, Sarit Aviel‐Ronen, Emily A. Vucic, Adi F. Gazdar, Stephen C. Lam, Ming‐Sound Tsao, Wan L. Lam · 2013 · PLoS ONE