The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Replication validity of genetic association studies
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Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
(1990) · Choice Reviews Online · doi:10.5860/choice.27-3338 · Cited by 35,305
Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease
(1959) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/22.4.719 · Cited by 14,689
Publication bias in clinical research
Easterbrook, P. J., Gopalan, R., Berlin, J. A., & Matthews, D. R. (1991) · The Lancet · doi:10.1016/0140-6736(91)90201-y · Cited by 3,109 · cited 1×
“others genotype 5,836 (20) 24 ICVD APOE (ε2/ε3/ε4) – allele ε4 vs.”
Quantitative Synthesis in Systematic Reviews
Lau, J., Ioannidis, J. P. A., & Schmid, C. H. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-127-9-199711010-00008 · Cited by 2,517 · cited 1×
“In 14 of 36 cases (39%), there was statistically significant heterogeneit”
BackgroundSelf-citationIoannidis, J. P. A. (1998) · JAMA · doi:10.1001/jama.279.4.281 · Cited by 632
Self-citationLarge Trials vs Meta-analysis of Smaller Trials: How Do Their Results Compare?
Cappelleri, J. C. (1996) · JAMA · doi:10.1001/jama.1996.03540160054033 · Cited by 336
Understanding research synthesis (meta-analysis).
Mosteller, F., & Colditz, G. A. (1996) · Annual Review of Public Health · doi:10.1146/annurev.pu.17.050196.000245 · Cited by 228
Research works printed but not linked: 15
- McCarthy, J.J. & Hilfiker, R. The use of single-nucleotide polymorphism maps in pharmacogenomics. Nature Biotechnol. 18, 505–508 (2000). · DOI · Paper page
- Khoury, M.J. & Little, J. Human genome epidemiology reviews: the beginning of something HuGE. Am. J. Epidemiol. 151, 2–3 (2000). · DOI
- Lau, J., Ioannidis, J.P.A. & Schmid, C.H. Summing up evidence: one answer is not always enough. Lancet 351, 123–127 (1998). · DOI · Paper page
- Hedges, L.V. & Olkin, I. Statistical Methods for Meta-analysis (Academic, Orlando, 1985).
- Cooper, H. & Hedges, L.V. (eds.) The Handbook of Research Synthesis (Russell Sage Foundation, New York, 1994).
- Ioannidis, J.P., Contopoulos-Ioannidis, D.G. & Lau, J. Recursive cumulative meta-analysis: a diagnostic for the evolution of total randomized evidence for group and individual patient data. J. Clin. Epidemiol. 52, 281–291 (1999). · DOI
- Ioannidis, J.P. & Lau, J. Evolution of treatment effects over time: empirical insight from recursive cumulative meta-analyses. Proc. Natl Acad. Sci. USA 98, 831–836 (2001). · DOI
- Gershon, E.S. & Cloninger, C.R. (eds) Genetic Approaches to Mental Disorders (American Psychiatric Press, Washington, DC, 1994).
- Vieland, V.J., Wang, K. & Huang, J. Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: comparative evaluation of model-based linkage methods for affected sib pair data. Hum. Hered. 51, 199–208 (2001). · DOI
- Greenberg, D.A. Summary of analyses of problem 2 simulated data for GAW11. Genet. Epidemiol. 17 (Suppl. 1), S429–447 (1999). · DOI
- Wang, K., Vieland, V. & Huang, J. A Bayesian approach to replication of linkage findings. Genet. Epidemiol. 17, S749–754 (1999). · DOI
- Gu, C. Province, M. & Rao, D.C. Meta-analysis of genetic linkage to quantitative trait loci with study-specific covariates: a mixed-effects model. Genet. Epidemiol. 17 (Suppl. 1), S599–604 (1999). · DOI
- Oxman, A.D. & Guyatt, G.H. A consumer's guide to subgroup analyses. Ann. Intern. Med. 116, 78–84 (1992). · DOI · Paper page
- Ioannidis, J.P. & Lau, J. Uncontrolled pearls, controlled evidence, meta-analysis, and the individual patient. J. Clin. Epidemiol. 51, 709–711 (1998). · DOI
- Yudkin, P.L. & Stratton, I.M. How to deal with regression to the mean in intervention studies. Lancet 347, 241–243 (1996). · DOI
Cited by
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
“For example, systematic reviews are now conducted to investigate cost-effectiveness [31], diagnostic [32] or prognostic questions [33], genetic associations [34], and policy making [35].”
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575
Metadata
- Authors
- Ioannidis, J. P. A., Ntzani, E. E., Trikalinos, T. A., & Contopoulos-Ioannidis, D. G.
- Venue
- Nature Genetics
- Published
- 2001-10-15
- Volume
- 29
- Issue
- 3
- Pages
- 306-309
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W1690786713
- Cited by
- 1,832
- References
- 8
- FWCI
- 44.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.