The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

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Items 101–200 of 916

  1. Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.
    Jared S. Burlison, Qiao-Ming Long, Y. Fujitani, C. Wright, M. Magnuson · 2008 · Developmental Biology
  2. Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia
    Kyoung Eun Lee, Michelle Spata, Lauren J. Bayne, Elizabeth L. Buza, Amy C. Durham, David Allman, Robert H. Vonderheide, Marie Celeste Simon · 2015 · Cancer Discovery
  3. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors
    Katherine LaRoque Jameson, Pawel Karol Mazur, Ashley M. Zehnder, Jiajing Zhang, Brian J. Zarnegar, Julien Sage, Paul A. Khavari · 2013 · Nature Medicine
  4. Human pluripotent stem cells: an emerging model in developmental biology
    Zeng‐Rong Zhu, Danwei Huangfu · 2013 · Development
  5. pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.
    M. Gannon, Elizabeth T. Ables, Laura A. Crawford, D. Lowe, M. F. Offield, M. Magnuson, C. Wright · 2008 · Developmental Biology
  6. Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma
    Shigekazu Murakami, David Shahbazian, Rishi Surana, W Zhang, H Chen, Garrett T. Graham, Shannon M. White, Louis M. Weiner, Chunling Yi · 2016 · Oncogene
  7. Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis.
    H. Algül, M. Treiber, M. Lesina, H. Nakhai, D. Saur, F. Geisler, A. Pfeifer, Stephan A Paxian, R. Schmid · 2007 · Journal of Clinical Investigation
  8. Fgf10 regulates hepatopancreatic ductal system patterning and differentiation
    P. Duc Si Dong, Chantilly Munson, William Norton, Cécile Crosnier, Xiufang Pan, Zhiyuan Gong, Carl J. Neumann, Didier Y. R. Stainier · 2007 · Nature Genetics
  9. Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
    Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S. et al. · 2018 · Nature Cell Biology
  10. The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
    von Figura, Guido, Fukuda, Akihisa, Roy, Nilotpal, Liku, Muluye E., Morris IV, John P., Kim, Grace E., Russ, Holger A., Firpo, Matthew A., Mulvihill, Sean J., Dawson, David W. et al. · 2014 · Nature Cell Biology
  11. Pancreas-Specific Cre Driver Lines and Considerations for Their Prudent Use
    Mark A. Magnuson, Anna B. Osipovich · 2013 · Cell Metabolism
  12. The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade.
    P. Jacquemin, F. Lemaigre, G. Rousseau · 2003 · Developmental Biology
  13. Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis
    Cassandra Burdziak, Direna Alonso‐Curbelo, Thomas Walle, José Santos Reyes, Francisco M. Barriga, Doron Haviv, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen et al. · 2023 · Science
  14. Genetic inducible fate mapping in mouse: Establishing genetic lineages and defining genetic neuroanatomy in the nervous system
    Alexandra L. Joyner, Mark Zervas · 2006 · Developmental Dynamics
  15. Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons
    Masaki Ueno, Yuka Nakamura, Jie Li, Zirong Gu, Jesse K. Niehaus, Mari Maezawa, Steven A. Crone, Martyn Goulding, Mark L. Baccei, Yutaka Yoshida · 2018 · Cell Reports
  16. Cellular Plasticity within the Pancreas— Lessons Learned from Development
    Sapna Puri, Matthias Hebrok · 2010 · Developmental Cell
  17. Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
    Y. Fujitani, Shuko Fujitani, Daniel F. Boyer, M. Gannon, Y. Kawaguchi, Michael Ray, M. Shiota, R. Stein, M. Magnuson, C. Wright · 2006 · Genes & Development
  18. Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic β cell
    Andreia Sofia Bernardo, Colin W. Hay, Kevin Docherty · 2008 · Molecular and Cellular Endocrinology
  19. KRAS-related proteins in pancreatic cancer
    Karen M. Mann, Haoqiang Ying, Joseph M. Juan, Nancy A. Jenkins, Neal G. Copeland · 2016 · Pharmacology & Therapeutics
  20. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer
    Mello, Stephano S., Valente, Liz J., Raj, Nitin, Seoane, Jose A., Flowers, Brittany M., McClendon, Jacob, Bieging-Rolett, Kathryn T., Lee, Jonghyeob, Ivanochko, Danton, Kozak, Margaret M. et al. · 2017 · Cancer Cell
  21. Metastatic pancreatic cancer is dependent on oncogenic Kras in mice
    Collins, Meredith A., Brisset, Jean-Christophe, Zhang, Yaqing, Bednar, Filip, Pierre, Josette, Heist, Kevin A., Galbán, Craig J., Galbán, Stefanie, di Magliano, Marina Pasca · 2012 · PLoS ONE
  22. STAT3 Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer
    Nagaraj S. Nagathihalli, Jason A. Castellanos, Chan-Juan Shi, Yugandhar Beesetty, Michelle L. Reyzer, R. Caprioli, X. Chen, A. Walsh, M. Skala, H. Moses et al. · 2015 · Gastroenterology
  23. Pancreatic neurogenin 3-expressing cells are unipotent islet precursors
    Renaud Desgraz, Pedro Luis Herrera · 2009 · Development
  24. Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation.
    T. Miyatsuka, H. Kaneto, T. Shiraiwa, T. Matsuoka, Kaoru Yamamoto, K. Kato, Yumiko Nakamura, S. Akira, K. Takeda, Y. Kajimoto et al. · 2006 · Genes & Development
  25. METTL13 methylation of eEF1A increases translational output to promote tumorigenesis
    Shuo Liu, Simone Hausmann, Scott M. Carlson, M. E. Fuentes, J. Francis, R. Pillai, Shane M. Lofgren, Laura Hulea, Kristofferson V. Tandoc, Jiu-Wei Lu et al. · 2019 · Cell
  26. Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex.
    Toshihiko Masui, Qiao-Ming Long, Thomas M. Beres, M. Magnuson, Raymond J MacDonald · 2007 · Genes & Development
  27. Mouse models of pancreatic cancer
    Marta Herreros‐Villanueva · 2012 · World Journal of Gastroenterology
  28. Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression
    Marta Pascual, Ibane Abasolo, Ana Mingorance, Albert Martı́nez, José Antonio del Rı́o, Christopher V.E. Wright, Francisco X. Real, Eduardo Soriano · 2007 · Proceedings of the National Academy of Sciences
  29. Genetically Engineered Mouse Models of Pancreatic Cancer
    Christoph Benedikt Westphalen, Kenneth P. Olive · 2012 · The Cancer Journal
  30. The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma
    Krah, Nathan M, De La O, Jean-Paul, Swift, Galvin H, Hoang, Chinh Q, Willet, Spencer G, Chen Pan, Fong, Cash, Gabriela M, Bronner, Mary P, Wright, Christopher VE, MacDonald, Raymond J et al. · 2015 · eLife
  31. Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas.
    M. Maestro, S. Boj, R. Luco, C. Pierreux, J. Cabedo, J. Servitja, M. German, G. Rousseau, F. Lemaigre, J. Ferrer · 2003 · Human Molecular Genetics
  32. Notch Signaling Is Required for Exocrine Regeneration After Acute Pancreatitis
    Siveke, Jens T., Lubeseder–Martellato, Clara, Lee, Marcel, Mazur, Pawel K., Nakhai, Hassan, Radtke, Freddy, Schmid, Roland M. · 2008 · Gastroenterology
  33. Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN.
    J. Siveke, H. Einwächter, B. Sipos, C. Lubeseder-Martellato, G. Klöppel, R. Schmid · 2007 · Cancer Cell
  34. Plasticity and Dedifferentiation within the Pancreas: Development, Homeostasis, and Disease
    Sapna Puri, Alexandra E. Folias, Matthias Hebrok · 2014 · Cell stem cell
  35. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis
    Shouhong Xuan, Matthew J. Borok, Kimberly J. Decker, Michele A. Battle, Stephen A. Duncan, Michael A. Hale, Raymond J. MacDonald, Lori Sussel · 2012 · Journal of Clinical Investigation
  36. GATA4 and GATA6 control mouse pancreas organogenesis.
    M. Carrasco, Irene Delgado, B. Soria, F. Martín, A. Rojas · 2012 · Journal of Clinical Investigation
  37. Directed Differentiation of Human Embryonic Stem Cells into the Pancreatic Endocrine Lineage
    Blaine Wesley Phillips, Hannes Hentze, William L. Rust, Qi-Ping Chen, Hiram Chipperfield, Ee-Kim Tan, Suman Abraham, Akila Sadasivam, Poh Loong Soong, Siew Tein Wang et al. · 2007 · Stem Cells and Development
  38. Neurovascular crosstalk between interneurons and capillaries is required for vision.
    Y. Usui, P. Westenskow, T. Kurihara, E. Aguilar, S. Sakimoto, Liliana P. Paris, Carli M. Wittgrove, Daniel Feitelberg, M. Friedlander, Stacey K. Moreno et al. · 2015 · Journal of Clinical Investigation
  39. Stabilization of β-catenin induces pancreas tumor formation
    P. Heiser, D. Cano, Limor Landsman, Grace E. Kim, J. Kench, D. Klimstra, M. Taketo, A. Biankin, M. Hebrok · 2008 · Gastroenterology
  40. Myc instructs and maintains pancreatic adenocarcinoma phenotype
    Nicole M. Sodir, R. Kortlever, V. Barthet, Tania Campos, L. Pellegrinet, Steven Kupczak, Panayiotis Anastasiou, L. Swigart, L. Soucek, M. Arends et al. · 2019 · bioRxiv
  41. Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas
    Sui Wang, Jingbo Yan, Daniel A. Anderson, Yanwen Xu, Maneesh C. Kanal, Zheng Cao, Christopher V.E. Wright, Guoqiang Gu · 2009 · Developmental Biology
  42. On the diabetic menu: Zebrafish as a model for pancreas development and function
    Mary D. Kinkel, Victoria Prince · 2009 · BioEssays
  43. Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man
    Sarah Elizabeth Flanagan, Elisa De Franco, Hana Lango Allen, Michele Zerah, Majedah M. Abdul-Rasoul, Julie Edge, Helen S. Stewart, Elham Alamiri, Khalid Hussain, Sam Wallis et al. · 2014 · Cell Metabolism
  44. Cellular and molecular mechanisms coordinating pancreas development
    Aimée Bastidas-Ponce, Katharina Scheibner, Heiko Lickert, Mostafa Bakhti · 2017 · Development
  45. Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.
    A. Fukuda, Y. Kawaguchi, K. Furuyama, S. Kodama, Masashi Horiguchi, T. Kuhara, M. Koizumi, Daniel F. Boyer, K. Fujimoto, R. Doi et al. · 2006 · Journal of Clinical Investigation
  46. Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells.
    S. Micallef, M. E. Janes, K. Knezevic, R. Davis, A. Elefanty, E. Stanley · 2005 · Diabetes
  47. PDX-1 and MafA Play a Crucial Role in Pancreatic β-Cell Differentiation and Maintenance of Mature β-Cell Function
    Hideaki Kaneto, Takeshi Miyatsuka, Dan Kawamori, Kaoru Yamamoto, Ken Kato, Toshihiko Shiraiwa, Naoto Katakami, Yoshimitsu Yamasaki, Munehide Matsuhisa, Taka‐aki Matsuoka · 2008 · Endocrine Journal
  48. Nestin expression in pancreatic exocrine cell lineages
    Alexandra Delacour, Virginie Népote, Andreas Trumpp, Pedro Luis Herrera · 2003 · Mechanisms of Development
  49. Ascl1 genetics reveals insights into cerebellum local circuit assembly
    Anamaria Sudarov, Rowena K. Turnbull, Euiseok J. Kim, Mélanie Lebel-Potter, F. Guillemot, A. Joyner · 2011 · Journal of Neuroscience
  50. An endothelial–mesenchymal relay pathway regulates early phases of pancreas development
    Patrick Jacquemin, Hideyuki Yoshitomi, Yasushige Kashima, Guy G. Rousseau, Frédéric P. Lemaigre, Kenneth S. Zaret · 2006 · Developmental Biology
  51. Wharton’s Jelly Mesenchymal Stem Cells as Candidates for Beta Cells Regeneration: Extending the Differentiative and Immunomodulatory Benefits of Adult Mesenchymal Stem Cells for the Treatment of Type 1 Diabetes
    R. Anzalone, M. Lo Iacono, Tiziana Loria, A. di Stefano, P. Giannuzzi, F. Farina, G. Larocca · 2011 · Stem Cell Reviews and Reports
  52. Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.
    John W. Lin, A. Biankin, Marko E. Horb, B. Ghosh, Nijaguna Prasad, N. Yee, M. Pack, S. Leach · 2004 · Developmental Biology
  53. Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation
    von Figura, Guido, Morris, John P, Wright, Christopher V E, Hebrok, Matthias · 2014 · Gut
  54. Specifying pancreatic endocrine cell fates
    Patrick Collombat, Jacob Hecksher‐Sørensen, Palle Serup, Ahmed Mansouri · 2006 · Mechanisms of Development
  55. A Dosage-Dependent Requirement for Sox9 in Pancreatic Endocrine Cell Formation
    Philip A. Seymour, K. Freude, Claire L. Dubois, H. Shih, N. Patel, M. Sander · 2008 · Developmental Biology
  56. A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma
    Nikki K. Lytle, Lesley Paige Ferguson, Nirakar Rajbhandari, Kathryn L. Gilroy, Raymond G. Fox, Anagha J. Deshpande, Christian M. Schürch, Michael Hamilton, Neil Robertson, Wei Lin et al. · 2019 · Cell
  57. In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes
    Wei-Da Li, Mio Nakanishi, A. Zumsteg, Matthew A. Shear, C. Wright, D. Melton, Qiao Zhou · 2014 · eLife
  58. Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb
    T. Kuwabara, Mohamedi N. Kagalwala, Yasuko Onuma, Yuzuru Ito, M. Warashina, Kazuyuki Terashima, Tsukasa Sanosaka, K. Nakashima, F. Gage, M. Asashima · 2011 · EMBO Molecular Medicine
  59. Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: an in vitro model to study islet differentiation.
    Brenda W. Kahan, L. M. Jacobson, D. Hullett, Jaime M Ochoada, T. Oberley, Katharine M. Lang, J. Odorico · 2003 · Diabetes
  60. An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants
    Zafra, Maria Paz, Parsons, Marie J., Kim, Jangkyung, Alonso-Curbelo, Direna, Goswami, Sukanya, Schatoff, Emma M., Han, Teng, Katti, Alyna, Fernandez, Maria Teresa Calvo, Wilkinson, John E. et al. · 2020 · Cancer Discovery
  61. The molecular and morphogenetic basis of pancreas organogenesis
    Hjalte List Larsen, Anne Grapin‐Botton · 2017 · Seminars in Cell and Developmental Biology
  62. A nonclassical bHLH–Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling
    Kei Hori, Justyna Cholewa-Waclaw, Yuji Nakada, Stacey M. Glasgow, Toshihiko Masui, Robert Michael Henke, Hendrik Wildner, Benedetta Martarelli, Thomas M. Beres, Jonathan A. Epstein et al. · 2008 · Genes & Development
  63. EZH2 couples pancreatic regeneration to neoplastic progression.
    Jon Mallen-St Clair, Rengin G. Soydaner-Azeloglu, K. Lee, Laura J. Taylor, A. Livanos, Y. Pylayeva-Gupta, G. Miller, R. Margueron, D. Reinberg, D. Bar-Sagi · 2012 · Genes & Development
  64. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma
    Raymond G. Fox, Nikki K. Lytle, Dawn V. Jaquish, Frederick D. Park, Takahiro Ito, Jeevisha Bajaj, Claire S. Koechlein, Bryan Zimdahl, Masato Yano, Janel L. Kopp et al. · 2016 · Nature
  65. Oncogenic KRas Suppresses Inflammation-Associated Senescence of Pancreatic Ductal Cells
    Kyoung Eun Lee, Dafna Bar‐Sagi · 2010 · Cancer Cell
  66. FGF2 Specifies hESC‐Derived Definitive Endoderm into Foregut/Midgut Cell Lineages in a Concentration‐Dependent Manner
    Jacqueline Ameri, A. Ståhlberg, J. Pedersen, J. Johansson, M. Johannesson, I. Artner, H. Semb · 2009 · Stem Cells
  67. Cdx2 regulates patterning of the intestinal epithelium
    Stephanie J. Grainger, Joanne G.A. Savory, David Lohnes · 2010 · Developmental Biology
  68. MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice
    Collins, Meredith A., Yan, Wei, Sebolt–Leopold, Judith S., Pasca di Magliano, Marina · 2014 · Gastroenterology
  69. Climbing Fiber Input Shapes Reciprocity of Purkinje Cell Firing
    Aleksandra Badura, Martijn Schonewille, Kai Voges, Elisa Galliano, Nicolas Renier, Zhenyu Gao, Laurens Witter, Freek E. Hoebeek, Alain Chédotal, Chris I. De Zeeuw · 2013 · Neuron
  70. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer
    Genovese, Giannicola, Carugo, Alessandro, Tepper, James, Robinson, Frederick Scott, Li, Liren, Svelto, Maria, Nezi, Luigi, Corti, Denise, Minelli, Rosalba, Pettazzoni, Piergiorgio et al. · 2017 · Nature
  71. Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas
    Isidoro Cobo, Paola Martinelli, Marta Flández, Latifa Bakiri, Mingfeng Zhang, Enrique Carrillo de Santa Pau, Jinping Jia, Victor Javier Sanchez-Arevalo Lobo, Diego Megı́as, Irene Felipe‐Abrio et al. · 2018 · Nature
  72. Aire-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for Aire in Thymic Epithelial Differentiation1
    G. Gillard, James L. Dooley, M. Erickson, L. Peltonen, A. Farr · 2007 · Journal of Immunology
  73. Exocrine pancreas development in zebrafish.
    N. Yee, K. Lorent, M. Pack · 2005 · Developmental Biology
  74. Kras as a key oncogene and therapeutic target in pancreatic cancer
    Meredith A. Collins, Marina Pasca di Magliano · 2014 · Frontiers in Physiology
  75. Pancreatic stem cells
    L. Murtaugh, D. Kopinke · 2008
  76. Dissecting the Role of Glucocorticoids on Pancreas Development
    Emilie Gesina, François Tronche, Pedro Luis Herrera, Bélinda Duchêne, Willemène Tales, Paul Czernichow, Bernadette Bréant · 2004 · Diabetes
  77. Identification and Manipulation of Biliary Metaplasia in Pancreatic Tumors
    Kathleen E. DelGiorno, Jason C. Hall, Kenneth K. Takeuchi, Fong C. Pan, C. Halbrook, M. Washington, K. Olive, J. Spence, B. Sipos, C. Wright et al. · 2013 · Gastroenterology
  78. Sox9 and programming of liver and pancreatic progenitors
    Yoshiya Kawaguchi · 2013 · Journal of Clinical Investigation
  79. Gata6 is an important regulator of mouse pancreas development.
    K. Decker, D. Goldman, Catherine L Grasch, L. Sussel · 2006 · Developmental Biology
  80. Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2+ Human Pancreatic Progenitors.
    Jacqueline Ameri, R. Borup, Christy Prawiro, Cyrille Ramond, Karen A. Schachter, R. Scharfmann, H. Semb · 2017 · Cell Reports
  81. Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1
    Tomoyuki Fujiyama, M. Yamada, Mami Terao, T. Terashima, Hiroyuki Hioki, Y. Inoue, Takayoshi Inoue, Norihisa Masuyama, K. Obata, Y. Yanagawa et al. · 2009 · Development
  82. FGF4 and Retinoic Acid Direct Differentiation of hESCs into PDX1-Expressing Foregut Endoderm in a Time- and Concentration-Dependent Manner
    Martina Johannesson, Anders Ståhlberg, Jacqueline Ameri, Fredrik Wolfhagen Sand, Karin Norrman, Henrik Semb · 2009 · PLoS ONE
  83. Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System
    Shinichi Yachida, Yasushi Totoki, Michaël Noë, Yoichiro Nakatani, Masafumi Horie, Kenta Kawasaki, Hiromi Nakamura, Mihoko Saito-Adachi, Masami Suzuki, Erina Takai et al. · 2021 · Cancer Discovery
  84. The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis
    M. Rajurkar, Wilfredo E. DeJesus-Monge, David R. Driscoll, Victoria A. Appleman, He Huang, Jennifer L. Cotton, D. Klimstra, L. Zhu, K. Simin, Lan Xu et al. · 2012 · Proceedings of the National Academy of Sciences of the United States of America
  85. MUC1 Enhances Tumor Progression and Contributes Toward Immunosuppression in a Mouse Model of Spontaneous Pancreatic Adenocarcinoma
    Teresa L. Tinder, Durai B. Subramani, Gargi Dan Basu, Judy Martina Bradley, Jorge L. Schettini, Million Arefayene, Todd C. Skaar, Pinku Mukherjee · 2008 · The Journal of Immunology
  86. Pancreatic Development and Disease
    David A. Cano, Matthias Hebrok, Martin Zenker · 2007 · Gastroenterology
  87. Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas.
    F. Esni, D. Stoffers, T. Takeuchi, S. Leach · 2004 · Mechanisms of Development
  88. BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis
    Laia Richart, Enrique Carrillo de Santa Pau, Ana Rio‐Machín, Mónica P. de Andrés, Juan C. Cigudosa, Victor Javier Sanchez-Arevalo Lobo, Francisco X. Real · 2016 · Nature Communications
  89. A Sox9/Fgf feed-forward loop maintains pancreatic organ identity
    Philip Allan Seymour, Hung-Ping Shih, Nisha A. Patel, Kristine Freude, Ruiyu Xie, Christopher J. Lim, Maike Sander · 2012 · Development
  90. Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells
    Toshihiko Masui, Galvin H. Swift, Tye G. Deering, Cheng-Cheng Shen, Ward S. Coats, Qiao-Ming Long, H. Elsässer, M. Magnuson, Raymond J MacDonald · 2010 · Gastroenterology
  91. The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer
    Brian C. Lewis, David S. Klimstra, HAROLD E. VARMUS · 2003 · Genes & Development
  92. Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue.
    Solomon Afelik, Yong-Long Chen, T. Pieler · 2006 · Genes & Development
  93. Conserved genetic signatures parcellate cardinal spinal neuron classes into local and projection subsets
    Osseward, Peter J., Amin, Neal D., Moore, Jeffrey D., Temple, Benjamin A., Barriga, Bianca K., Bachmann, Lukas C., Beltran, Fernando, Gullo, Miriam, Clark, Robert C., Driscoll, Shawn P. et al. · 2021 · Science
  94. Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates.
    Elisabetta Zecchin, A. Mavropoulos, N. Devos, A. Filippi, N. Tiso, Dirk Meyer, B. Peers, M. Bortolussi, F. Argenton · 2004 · Developmental Biology
  95. Transcription factors direct the development and function of pancreatic β cells
    S. Chakrabarti, R. Mirmira · 2003 · Trends in Endocrinology and Metabolism
  96. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    P. Hermann, P. Sancho, M. Cañamero, P. Martinelli, Francesc Madriles, P. Michl, T. Gress, R. de Pascual, L. Gandía, C. Guerra et al. · 2014 · Gastroenterology
  97. Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice
    Ainhoa Iglesias–Ara, Matilde Murga, Usua Laresgoiti, Anouchka Skoudy, Irantzu Bernales, Asier Fullaondo, Bernardino Moreno, Josep Lloreta, Seth J. Field, Francisco X. Real et al. · 2004 · Journal of Clinical Investigation
  98. Role of transcription factors in the transdifferentiation of pancreatic islet cells
    Talitha van der Meulen, Mark O. Huising · 2015 · Journal of Molecular Endocrinology
  99. Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulation
    Jing Liu, Spencer G. Willet, E. Bankaitis, Yanwen Xu, Chris Wright, Guo-Qiang Gu · 2013 · Genesis
  100. In vitro transdifferentiation of hepatoma cells into functional pancreatic cells.
    Wan-Chun Li, Marko E. Horb, D. Tosh, J. Slack · 2005 · Mechanisms of Development