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Genetic analysis of basophil function in vivo
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“When mast cell- or basophil-bound IgE antibodies recognize antigens that are at least bivalent, rapid aggregation of the FcεRI initiates complex intra-cellular signaling pathways. This ultimately results in the release, by such activated effector cells, of a wide variety of mediators with diverse biological effects [5, 6, 8–11].”
From Mast cells and IgE in defense against lethality of venoms: Possible “benefit” of allergy (2020) · cites this paper as [9]
In the citing paper
“FcεRI are expressed on mast cells, that reside in most vascularized tissues in mammals and other vertebrates, and on basophilic granulocytes (“basophils”), that ordinarily circulate in very low numbers in the blood but which can be recruited to sites of inflammation [3, 5–10].”
From Mast cells and IgE in defense against lethality of venoms: Possible “benefit” of allergy (2020) · cites this paper as [9]
In the citing paper
“Basophils activated via FcεRI aggregation can release a panel of mediators partially overlapping with those of mast cells, but, as compared to mast cells, they contain much lower amounts of proteases and appear to produce fewer cytokines and chemokines [8–10].”
From Mast cells and IgE in defense against lethality of venoms: Possible “benefit” of allergy (2020) · cites this paper as [9]
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Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
Cyster, J. G. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115628 · Cited by 856
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Self-citationMast cells and IgE in defense against venoms: Possible “good side” of allergy?
Galli, S. J., Starkl, P., Marichal, T., & Tsai, M. (2016) · Allergology International · doi:10.1016/j.alit.2015.09.002 · Cited by 73
Metadata
- Authors
- Sullivan, B. M., Liang, H.-E., Bando, J. K., Wu, D., Cheng, L. E., McKerrow, J. K., Allen, C. D. C., & Locksley, R. M.
- Venue
- Nature Immunology
- Published
- 2011-05-08
- Volume
- 12
- Issue
- 6
- Pages
- 527-535
- ISSN
- 1529-2908
- 1529-2916
- PMC
- PMC3271435
- Cited by
- 235
- References
- 1
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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