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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Neill, Daniel R., Wong, See Heng, Bellosi, Agustin, Flynn, Robin J., Daly, Maria, Langford, Theresa K. A., Bucks, Christine, Kane, Colleen M., Fallon, Padraic G., Pannell, Richard, Jolin, Helen E., McKenzie, Andrew N. J.·2010·Nature
DOI 10.1038/nature08900PMC PMC2862165
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Research works printed but not linked: 24

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  7. Urban, J. F. J. et al. IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis . Immunity 8, 255–264 (1998) · DOI
  8. Min, B. et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J. Exp. Med. 200, 507–517 (2004) · DOI
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  12. Yoshimoto, T. et al. Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. Nature Immunol. 10, 706–712 (2009) · DOI
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  14. Walter, D. M. et al. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J. Immunol. 167, 4668–4675 (2001) · DOI
  15. Voehringer, D., Reese, T. A., Huang, X., Shinkai, K. & Locksley, R. M. Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J. Exp. Med. 203, 1435–1446 (2006) · DOI
  16. Arinobu, Y. et al. Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. Proc. Natl Acad. Sci. USA 102, 18105–18110 (2005) · DOI · Paper page
  17. Haig, D. M. et al. Effects of stem cell factor (kit-ligand) and interleukin-3 on the growth and serine proteinase expression of rat bone-marrow-derived or serosal mast cells. Blood 83, 72–83 (1994) · DOI
  18. McKenzie, G. J., Fallon, P. G., Emson, C. L., Grencis, R. K. & McKenzie, A. N. Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J. Exp. Med. 189, 1565–1572 (1999) · DOI
  19. Fallon, P. G. et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J. Exp. Med. 203, 1105–1116 (2006) · DOI
  20. Shinkai, Y. et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855–867 (1992) · DOI · Paper page
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Metadata

Authors
Neill, D. R., Wong, S. H., Bellosi, A., Flynn, R. J., Daly, M., Langford, T. K. A., Bucks, C., Kane, C. M., Fallon, P. G., Pannell, R., Jolin, H. E., & McKenzie, A. N. J.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2010-04
Volume
464
Issue
7293
Pages
1367-1370
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/nature08900
PMC
PMC2862165
Cited by
1,938
References
0
Language
en
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CoChat. (2026). Citation check: Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. https://app.cochat.ai/papers/10.1038/nature08900
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Neill, D. R., Wong, S. H., Bellosi, A., Flynn, R. J., Daly, M., Langford, T. K. A., Bucks, C., Kane, C. M., Fallon, P. G., Pannell, R., Jolin, H. E., & McKenzie, A. N. J. (2010). Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature. https://doi.org/10.1038/nature08900