Srebp-controlled glucose metabolism is essential for NK cell functional responses

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Horton, J. D., Goldstein, J. L., & Brown, M. S. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15593 · Cited by 4,794

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Horton, J. D., Goldstein, J. L., & Brown, M. S. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215593 · Cited by 4,092

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Cheng, S.-C., Quintin, J., Cramer, R. A., Shepardson, K. M., Saeed, S., Kumar, V., Giamarellos-Bourboulis, E. J., Martens, J. H. A., Rao, N. A., Aghajanirefah, A., et al. (2014) · Science · doi:10.1126/science.1250684 · Cited by 2,224

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

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Human natural killer cells

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Fueling Immunity: Insights into Metabolism and Lymphocyte Function

Pearce, E. L., Poffenberger, M. C., Chang, C.-H., & Jones, R. G. (2013) · Science · doi:10.1126/science.1242454 · Cited by 1,363

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Huang, S. C., Everts, B., Ivanova, Y., O’Sullivan, D., Nascimento, M., Smith, A. M., Beatty, W. L., Love-Gregory, L. D., Lam, W. Y., O’Neill, C. M., et al. (2014) · Nature Immunology · doi:10.1038/ni.2956 · Cited by 1,256

Targeting natural killer cells in cancer immunotherapy

Guillerey, C., Huntington, N. D., & Smyth, M. J. (2016) · Nature Immunology · doi:10.1038/ni.3518 · Cited by 1,081

Global burden of cancer attributable to high body-mass index in 2012: a population-based study

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De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

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Fatty acids are crucial to fuel NK cells upon acute retrovirus infection

Schimmer, S., Mittermüller, D., Werner, T., Görs, P. E., Meckelmann, S. W., Finlay, D. K., Dittmer, U., & Littwitz-Salomon, E. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1296355 · Cited by 20

Metabolic heterogeneity in tumor microenvironment – A novel landmark for immunotherapy

Chen, C., Han, P., & Qing, Y. (2024) · Autoimmunity Reviews · doi:10.1016/j.autrev.2024.103579 · Cited by 17

Targeting glutamine metabolism crosstalk with tumor immune response

Dong, C., Zhao, Y., Han, Y., Li, M., & Wang, G. (2025) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2024.189257 · Cited by 21

TGFβ drives mitochondrial dysfunction in peripheral blood NK cells during metastatic breast cancerPreprint

Slattery, K., Zaiatz-Bittencourt, V., Woods, E., Brennan, K., Marks, S. J., Chew, S. M., Conroy, M. R., Goggin, C., Kennedy, J., Finlay, D. K., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/648501 · Cited by 17

Metabolic reprogramming of NK cells drives anti-tumor immunity

Yang, P., Wang, W., Liu, Q., Mu, S., Zha, Y., Yan, W., Yuan, B., & Yang, J. (2025) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2025.104859 · Cited by 20

Choline in immunity: a key regulator of immune cell activation and function

Maia, C., Fung, C. W., & Sánchez‐López, E. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1617077 · Cited by 18

Immune and metabolic checkpoints blockade: Dual wielding against tumors

Kazemi, M. H., Najafi, A., Karami, J., Ghazizadeh, F., Yousefi, H., Falak, R., & Safari, E. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107461 · Cited by 16

NK cells vs. obesity: A tale of dysfunction & redemption

Barra, C. D., O'Shea, D. B., & Hogan, A. E. (2023) · Clinical Immunology · doi:10.1016/j.clim.2023.109744 · Cited by 17

Lactate Metabolic Reprogramming Mediated by CircRNA–LDHA Complex Facilitates Innate Immune Evasion of Liver Cancer

Shen, H., Liu, B., He, J., Zhao, W., Li, W., Ma, L., Hou, L., Wáng, Y., Jin, C., Chang, Y., et al. (2025) · Advanced Science · doi:10.1002/advs.202509989 · Cited by 16

Metabolic heterogeneity and immunocompetence of infiltrating immune cells in the breast cancer microenvironment (Review)

Chen, H., Sun, Y., Yang, Z., Yin, S., Li, Y., Tang, M., Zhu, J.-P., & Zhang, F. (2021) · Oncology Reports · doi:10.3892/or.2021.7946 · Cited by 15

Immunometabolic Signature during Respiratory Viral Infection: A Potential Target for Host-Directed Therapies

dos Reis, L. M., Berçot, M. R., Castelucci, B. G., Martins, A. J. E., Castro, G., & Moraes‐Vieira, P. M. (2023) · Viruses · doi:10.3390/v15020525 · Cited by 17

SREBP2 restricts osteoclast differentiation and activity by regulating IRF7 and limits inflammatory bone erosion

Kim, H., Choi, I. A., Umemoto, A., Bae, S., Kaneko, K., Mizuno, M., Γιαννοπούλου, Ε., Pannellini, T., Deng, L., & Park‐Min, K. (2024) · Bone Research · doi:10.1038/s41413-024-00354-4 · Cited by 15

Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance

Goh, W., Scheer, S., Jackson, J. T., Hediyeh-zadeh, S., Delconte, R. B., Schuster, I. S., Andoniou, C. E., Rautela, J., Degli‐Esposti, M. A., Davis, M. J., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108285 · Cited by 15

Metabolic interventions: A new insight into the cancer immunotherapy

Yu, T., Dong, T., Eyvani, H., Fang, Y., Wang, X., Zhang, X., & Lu, X. (2020) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108659 · Cited by 16

Natural Killer Cells Integrate Signals Received from Tumour Interactions and IL2 to Induce Robust and Prolonged Anti-Tumour and Metabolic Responses.

Kedia-Mehta, N., Choi, C., McCrudden, A., Littwitz-Salomon, E., Fox, P. G., Gardiner, C. M., & Finlay, D. K. (2019) · PubMed · doi:10.20900/immunometab20190014 · Cited by 15

Unraveling the complexities of diet induced obesity and glucolipid dysfunction in metabolic syndrome

Dutta, B., Tripathy, A., Archana, P. R., & Kamath, S. U. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01837-y · Cited by 19

Harnessing the Power of CAR-NK Cells for Solid Tumors: Challenges, Innovations, and Future Frontiers in Immunotherapy

An, M., Yan, J., Liu, B., & Liu, Q. (2026) · 癌症：英文版 · doi:10.34133/cancomm.0023 · Cited by 17

NK cell immunometabolism as target for liver cancer therapy

Wang, J., Liu, X., Jin, T., Cao, Y., Tian, Y., & Xu, F. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109193 · Cited by 14

Advanced nanomaterials for enhanced immunotherapy via metabolic regulation

Li, X., Ding, B., Zheng, P., Ma, P., & Lin, J. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215540 · Cited by 14

Natural killer cells at the forefront of cancer immunotherapy with immune potency, genetic engineering, and nanotechnology

Pan, W., Tao, T., Qiu, Y., Zhu, X. M., & Zhou, X. (2023) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2023.104231 · Cited by 16

Powering immunity: mitochondrial dynamics in natural killer cells

Verhezen, T., Wouters, A., Smits, E., & Waele, J. D. (2025) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2025.04.004 · Cited by 13

ACLY-matizing Macrophages to Histone Modification during Immunometabolic Reprogramming

Williams, N. C., & O'Neill, L. A. J. (2020) · Trends in Immunology · doi:10.1016/j.it.2019.12.009 · Cited by 14

Expression of Nutrient Transporters on NK Cells During Murine Cytomegalovirus Infection Is MyD88-Dependent

Khan, A. U. H., Almutairi, S. M., Ali, A. K., Salcedo, R., Stewart, C. A., Wang, L., & Lee, S.-H. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.654225 · Cited by 14

Srebf1c preserves hematopoietic stem cell function and survival as a switch of mitochondrial metabolism

Lu, Y., Zhang, Z., Wang, S., Qi, Y., Chen, F., Xu, Y., Shen, M., Chen, M., Chen, N., Yang, L., et al. (2022) · Stem Cell Reports · doi:10.1016/j.stemcr.2022.01.011 · Cited by 15

Cutting edge: Metabolic immune reprogramming, reactive oxygen species, and cancer

Aria, H., Ghaedrahmati, F., & Ganjalıkhani-Hakemi, M. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30303 · Cited by 14

Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease

Ham, J., Yang, W., & Kim, H. Y. (2025) · Immune Network · doi:10.4110/in.2025.25.e3 · Cited by 13

Anti‐Tumor Strategies Targeting Nutritional Deprivation: Challenges and Opportunities

Shi, J., Han, W., Wang, J., & Kong, X. (2025) · Advanced Materials · doi:10.1002/adma.202415550 · Cited by 14

Chronic HBV infection impairs the glucose metabolism and effector function of NK cells via HBsAg/IL-15/mTOR axis

Yu, Y., Wang, Z., Yang, A., Wang, Y., Bao, C., Li, Z., Han, Q., Zhao, H., & Zhang, J. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-08069-y · Cited by 12

Metabolic regulation of NK cell antiviral functions during cytomegalovirus infection

Cimpean, M., & Cooper, M. A. (2023) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiad018 · Cited by 12

Insights into the malfunctioning of the mitochondrial citrate carrier: Implications for cell pathology

Zara, V., Assalve, G., & Ferramosca, A. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166758 · Cited by 12

Tuning cellular metabolism for cancer virotherapy

Xiong, D., Wang, Q., Wang, W., & Sun, Z. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216924 · Cited by 12

Inhibition of ATP-citrate lyase by bempedoic acid protects against abdominal aortic aneurysm formation in mice

Puertas-Umbert, L., Alonso, J., Blanco-Casoliva, L., Almendra‐Pegueros, R., Camacho, M., Rodríguez‐Sinovas, A., Galán, M., Roglans, N., Laguna, J. C., Martínez‐González, J., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.117876 · Cited by 12

Innate Cytokine Induced Early Release of IFNγ and CC Chemokines from Hypoxic Human NK Cells Is Independent of Glucose

Velásquez, S. Y., Himmelhan, B. S., Kassner, N., Coulibaly, A., Schulte, J., Brohm, K., & Lindner, H. A. (2020) · Cells · doi:10.3390/cells9030734 · Cited by 12

Decreased glycolysis induced dysfunction of NK cells in Henoch-Schonlein purpura patients

Chai, W., Wang, X., Wang, W., Wang, H., Mou, W., & Gui, J. (2020) · BMC Immunology · doi:10.1186/s12865-020-00382-9 · Cited by 12

Oxidative stress in pituitary neuroendocrine tumors: Affecting the tumor microenvironment and becoming a new target for pituitary neuroendocrine tumor therapy

Zhou, Y., Zhang, A., Fang, C., Yuan, L., Shao, A., Xu, Y., & Zhou, D. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14315 · Cited by 12

Metabolic programming of organ‐specific natural killer cell responses

Delconte, R. B., & Sun, J. C.-Y. (2024) · Immunological Reviews · doi:10.1111/imr.13333 · Cited by 12

Overview of Strategies to Improve Therapy against Tumors Using Natural Killer Cell

Yang, C.-P., Li, Y., Yang, Y.-Z., & Chen, Z. (2020) · Journal of Immunological Research · doi:10.1155/2020/8459496 · Cited by 13

Oxidative phosphorylation at the crossroads of cancer: Metabolic orchestration, stromal collusion, and emerging therapeutic horizons

Chen, K., Wang, W., Shu, H.-Y., Lyu, J., Cui, W., & Fang, H. (2025) · Interdisciplinary medicine · doi:10.1002/inmd.70054 · Cited by 11

Unraveling the mystery of citrate transporters in Alzheimer’s disease: An updated review

Mukherjee, A. G., Mishra, S., Gopalakrishnan, A. V., Kannampuzha, S., Murali, R., Wanjari, U. R., Stany, B. K., Vellingiri, B., Madhyastha, H., Deepankumar, K., et al. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102726 · Cited by 11

Polyamines in pancreatic cancer: reshaping the immunosuppressive tumor microenvironment

Jiang, S., Ren, B., Ding, C., Du, C., Cao, Z., Yang, G., Huang, H., & Zhang, T. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.218016 · Cited by 12

Natural Killer Cell‐Mediated Antitumor Immunity: Molecular Mechanisms and Clinical Applications

Luo, N., Chen, C., Zhou, W., Hao, J., He, S., Liu, Y., Ku, Y., Huang, L., Zhang, C., Shu, Y., et al. (2025) · MedComm · doi:10.1002/mco2.70387 · Cited by 12

Immuno-onco-metabolism and Therapeutic Resistance

Mir, M. A., Aisha, S., Nisar, S., Qayoom, H., & Mehraj, U. (2022) · Springer eBooks · doi:10.1007/978-981-16-6226-3_3 · Cited by 11

Alpha‐ketoglutaric acid based polymeric particles for cutaneous wound healing

Jaggarapu, M. M. C. S., Ghosh, D., Johnston, T. M., Yaron, J. R., Mangal, J. L., Inamdar, S., Gosangi, M., Rege, K., & Acharya, A. P. (2023) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37539 · Cited by 11

Enhanced Proinflammatory Cytokine Production and Immunometabolic Impairment of NK Cells Exposed to Mycobacterium tuberculosis and Cigarette Smoke

Rao, Y., Gai, X., Le, Y., Xiong, J., Liu, Y., Zhang, X., Wang, J., Cao, W., & Sun, Y. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.799276 · Cited by 11

Lactic acid: a narrative review of a promoter of the liver cancer microenvironment

Chen, J., He, G., Cai, D., Giovannetti, E., Inamura, K., Liu, S., & Ma, W. (2024) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo-24-368 · Cited by 10

Fatty acid metabolism: A new target for nasopharyngeal carcinoma therapy

Li, J., Ping, P., Li, Y., & Xu, X. (2024) · Chinese Journal of Cancer Research · doi:10.21147/j.issn.1000-9604.2024.06.05 · Cited by 10

Unique metabolism and protein expression signature in human decidual NK cells

Wang, P., Liang, T., Zhan, H., Zhu, M., Wu, M., Qian, L., Zhou, Y. Y., & Ni, F. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1136652 · Cited by 9

No time to die: Epigenetic regulation of natural killer cell survival

Hermans, L., & O’Sullivan, T. E. (2024) · Immunological Reviews · doi:10.1111/imr.13314 · Cited by 9

Optimizing glutamine concentration enhances ex vivo expansion of natural killer cells through improved redox status

Ying, D., Zhang, G., Huang, H., Tan, W., & Cai, H. (2024) · Biotechnology Progress · doi:10.1002/btpr.3464 · Cited by 9

CPT2 inhibition enhances selective autophagy and proliferation in colorectal cancer via GPAT4-dependent glycerophospholipid biosynthesis

Li, K., Wang, H., Li, C., Xiao, M., Luo, Y., Shen, S., Li, G., Fu, Y., Chen, W., Shao, R., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-08877-0 · Cited by 9

Host-related Determinants of Response to Immunotherapy in Non-small Cell Lung Cancer: The Interplay of Body Composition, Metabolism, Sex and Immune Regulation

Santo, V., Brunetti, L., Pecci, F., Peroni, M., Barnini, G., Paoloni, F., Buti, S., Tiseo, M., Ricciuti, B., Pinato, D. J., et al. (2025) · Current Oncology Reports · doi:10.1007/s11912-025-01718-7 · Cited by 10

Unraveling the link between cholesterol and immune system in cancer: From biological mechanistic insights to clinical evidence. A narrative review

Pecci, F., Cognigni, V., Giudice, G. C., Paoloni, F., Cantini, L., Saini, K. S., Abushukair, H. M., Naqash, A. R., Cortellini, A., Mazzaschi, G., et al. (2025) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2025.104654 · Cited by 9

Inhibitors of the NMDA-Nitric Oxide Signaling Pathway Protect Against Neuronal Atrophy and Synapse Loss Provoked by l-alpha Aminoadipic Acid-treated Astrocytes

David, J., O'Toole, E., O'Reilly, K., Thuery, G., Aßmann, N., Finlay, D. K., & Harkin, A. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.09.023 · Cited by 9

Chemokine (C-X-C motif) ligand 1 maintains the immune surveillance function of natural killer cells via the PDK2/mTOR signaling pathway

Zeng, X., Dong, X., Ma, Y., & Yao, J. (2022) · Cell Biology and Toxicology · doi:10.1007/s10565-022-09708-2 · Cited by 9

Aspartate availability drives differential engagement of the malate-aspartate shuttle

Brunner, J. S., Bridgeman, A. E., Jackson, B. T., Chakraborty, S., Fagoaga-Eugui, M., Paras, K. I., Xie, A., Arnold, P. K., Losner, J., & Finley, L. W. S. (2026) · Molecular Cell · doi:10.1016/j.molcel.2026.02.004 · Cited by 8

Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle

Xie, A., Brunner, J. S., Chakraborty, S., Montero, A. M., Bridgeman, A. E., Paras, K. I., Cui, R., Fagoaga-Eugui, M., Komza, M., Arnold, P. K., et al. (2026) · Cell · doi:10.1016/j.cell.2026.01.028 · Cited by 12

Recent advancements in nanomedicine based lipid metabolism for tumour immunotherapy

Zhao, Y., Zhang, X., An, M., Zhang, J., & Liu, Y. (2023) · Journal of drug targeting · doi:10.1080/1061186x.2023.2283829 · Cited by 8

Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level

Corkish, C., de Aguiar, C. F., & Finlay, D. K. (2024) · Nature Communications · doi:10.1038/s41467-024-54516-3 · Cited by 8

Deciphering metabolic crosstalk in context: lessons from inflammatory diseases

Verheijen, F. W., Minh, T. T. N., Chang, J., Broere, F., Zaal, E. A., & Berkers, C. R. (2024) · Molecular Oncology · doi:10.1002/1878-0261.13588 · Cited by 8

Phenotypes, mechanisms, and therapeutic strategies of natural killer cell immunosenescence

Guo, Z., Wu, F., Chen, Y., Xu, J. M., & Chen, Z. (2025) · Immunity & Ageing · doi:10.1186/s12979-025-00534-8 · Cited by 9

Vitamin combination promotes ex vivo expansion of NK-92 cells by reprogramming glucose metabolism

Fu, Y., Chen, Y., Xie, Z., Huang, H., Tan, W., & Cai, H. (2022) · Bioresources and Bioprocessing · doi:10.1186/s40643-022-00578-4 · Cited by 7

Research Hotspots and Trends in Global Cancer immunometabolism:A Bibliometric Analysis from 2000 to 2023

Chen, S., Liu, J., He, G. Q., Tang, N., & Zeng, Y. (2024) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s495330 · Cited by 7

Metabolic Rewiring in the Tumor Microenvironment to Support Immunotherapy: A Focus on Neutrophils, Polymorphonuclear Myeloid-Derived Suppressor Cells and Natural Killer Cells

Barbaro, A. D. L., Palano, M. T., Cucchiara, M., Gallazzi, M., Mortara, L., & Bruno, A. (2021) · Vaccines · doi:10.3390/vaccines9101178 · Cited by 7

Identification of nafamostat mesylate as a selective stimulator of NK cell IFN-γ production via metabolism-related compound library screening

Yang, Q., Zhang, S., Wu, S., Yao, B., Wang, L., Li, Y., Peng, H., Huang, M., Bi, Q., Xiong, P., et al. (2022) · Immunologic Research · doi:10.1007/s12026-022-09266-z · Cited by 7

NK Cell Metabolism and the Potential Offered for Cancer Immunotherapy

Gardiner, C. M. (2019) · Immunometabolism · doi:10.20900/immunometab20190005 · Cited by 7

Autofluorescence lifetime imaging classifies human lymphocyte activation and subtypePreprint

Schmitz, R. L., Tweed, K. E., Rehani, P. R., Samimi, K., Riendeau, J. M., Jones, I., Maly, E. M., Guzman, E. C., Forsberg, M. H., Shahi, A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.23.525260 · Cited by 7

Molecular Targets for Cannabinoids in Natural Killer Cells: Do They Modulate the Antitumor Activity?

Olivas-Aguirre, M., Gutiérrez-Iñiguez, C., Pottosin, I. I., & Dobrovinskaya, O. R. (2024) · Receptors · doi:10.3390/receptors3020007 · Cited by 6

The role of immune cells glycolysis in neuroinflammation secondary to intracerebral hemorrhage

Luo, B., Liu, S., Zheng, L., Zhang, B., Shang, Y., Shang, T., Zheng, J., Kuang, B., & Zou, W. (2025) · Clinical Immunology · doi:10.1016/j.clim.2025.110543 · Cited by 7

Effects of Rapid Weight Loss on the Immune System in Combat Sports Athletes: A Systematic Review

Lee, H. S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27010508 · Cited by 6

Tubular insulin-induced gene 1 deficiency promotes NAD+ consumption and exacerbates kidney fibrosis

Li, S., Qin, J., Zhao, Y., Wang, J., Huang, S., & Yu, X. (2024) · EMBO Molecular Medicine · doi:10.1038/s44321-024-00081-7 · Cited by 6

In-depth analysis of the interplay between oncogenic mutations and NK cell-mediated cancer surveillance in solid tumors

Pesini, C., Artal, L., Bernal, J. P., Sánchez‐Martínez, D., Pardo, J., & Ramírez-Labrada, A. (2024) · OncoImmunology · doi:10.1080/2162402x.2024.2379062 · Cited by 6

SHORT-TERM INFLAMMATORY BIOMARKER PROFILES ARE ASSOCIATED WITH DEFICIENT MITOCHONDRIAL BIOENERGETICS IN LYMPHOCYTES OF SEPTIC SHOCK PATIENTS—A PROSPECTIVE COHORT STUDY

Nedel, W. L., Strogulski, N. R., Rodolphi, M. S., Kopczynski, A., Montes, T. H. M., & Portela, L. V. (2022) · Shock · doi:10.1097/shk.0000000000002055 · Cited by 6

Local and systemic features of ILC immunometabolism

Surace, L., & Santo, J. P. D. (2022) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000722 · Cited by 6

Leptin, NK cells, and the weight of immunity: Insights into obesity

de Andrade, A. G., Vanderley, S. E. R., Marques, L. C. D. S., Almeida, F. S., Silva, L. H. A. C., & Keesen, T. S. L. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113992 · Cited by 7

ACLY promotes NK cell effector function by regulating glycolysis and histone acetylation

Sohn, H., Kolicheski, A., Poursine‐Laurent, J., Tran, J., Wang, Y., Gan, K., Tobin, J. M., Saucier, N., Fehniger, T. A., Payton, J. E., et al. (2025) · The Journal of Immunology · doi:10.1093/jimmun/vkaf209 · Cited by 6

Natural killer cells in kidney immune surveillance, injury and fibrosis

Horowitz, A., & Heeger, P. S. (2025) · Nature Reviews Nephrology · doi:10.1038/s41581-025-01029-x · Cited by 6

Metabolic requirements of CD160 expressing memory‐like NK cells in Gram‐negative bacterial infection

Preechanukul, A., Saiprom, N., Rochaikun, K., Moonmueangsan, B., Phunpang, R., Ottiwet, O., Kongphrai, Y., Wapee, S., Janon, R., Dunachie, S. J., et al. (2024) · Clinical & Translational Immunology · doi:10.1002/cti2.1513 · Cited by 5

Non-Specific Elevated Serum Free Fatty Acids in Lung Cancer Patients: Nutritional or Pathological?

Shao, Y., Wang, S., Xu, X., Sun, C., Cai, F., Guo, Q., Wu, M., Yang, M., & Wu, X. (2024) · Nutrients · doi:10.3390/nu16172884 · Cited by 5

Pharmacological therapy targeting the immune response in atherosclerosis

Wu, Y., Xu, Y., & Xu, L. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112974 · Cited by 5

Transcriptome Analysis Reveals That SREBP Modulates a Large Repertoire of Genes Involved in Key Cellular Functions in Penaeus vannamei, although the Majority of the Dysregulated Genes Are Unannotated

Zheng, X., Huang, Z., Liu, Z., Zheng, Z., Zhang, Y., & Aweya, J. J. (2022) · Genes · doi:10.3390/genes13112057 · Cited by 6

Dietary lipid overload creates a suppressive environment that impedes the antiviral functions of NK cells

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Mitochondria orchestrated immune microenvironment and response in health and disease-clinically relevant outlook and recommendations

Yang, K., Bi, J., Cao, Y., He, D., Fu, S., & Guo, W. (2026) · Journal of Advanced Research · doi:10.1016/j.jare.2026.03.048 · Cited by 4

Natural killer cell exhaustion in ovarian cancer: from molecular suppression to therapeutic revival

Ning, J., & Yao, L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1709075 · Cited by 4

Natural killer and CAR-NK cell therapies in urological cancers: Progress, mechanistic lessons from CAR-T, and future directions

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Acquired resistance of cancer therapies: Mechanisms and perspectives

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Cholesterol metabolism in immune cells: From mechanisms to therapeutic opportunities

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Advancing CAR-NK cell therapy in solid tumors: Current landscape and future directions

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Stem Cell Therapy and Innate Lymphoid Cells

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Natural killer loops: pyruvate in, lactate out

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Glucose Metabolism Reprogramming of Immune Cells in the Microenvironment of Pancreatic and Hepatobiliary Cancers

Zhao, Y., Zhu, W., Dong, S., Zhang, H., & Zhou, W. (2025) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.16873 · Cited by 5

Make killers sweeter: targeting metabolic checkpoints of NK cells

Wei, H., & Fu, B. (2020) · Nature Immunology · doi:10.1038/s41590-020-0738-x · Cited by 4

Chitosan-Based Sustained Expression of Sterol Regulatory Element-Binding Protein 1a Stimulates Hepatic Glucose Oxidation and Growth in Sparus aurata

Rashidpour, A., Wu, Y., Almajano, M. P., Fàbregas, A., & Metón, I. (2023) · Marine Drugs · doi:10.3390/md21110562 · Cited by 4

Crosstalk between the tumor microenvironment and tumor cells through exosomes: Roles in tumor metabolism and progression

Shi, Y., Du, J., Pan, W., Zhang, H., & Ba, Y. (2023) · journal of nutritional oncology · doi:10.1097/jn9.0000000000000008 · Cited by 5

Instruction of Immunometabolism by Adipose Tissue: Implications for Cancer Progression

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Unlocking the power of innate lymphoid cell plasticity in the tumor microenvironment: A revolutionary pathway for cancer immunotherapy

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Glycolytic diversity drives immune complexity in cancer

Wu, C.-Y., Huang, C.-X., Yuan, W., & Kuang, D. (2025) · Trends in Immunology · doi:10.1016/j.it.2025.11.002 · Cited by 4

Glucose metabolic reprogramming as a driver of immunosuppression in the tumour microenvironment

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Tumor–immune metabolic tug-of-war: from immune escape to targeting metabolic rewiring in cancer therapy

Foglia, B., Nurcis, J., Signorini, M., & Cannito, S. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1823145 · Cited by 3

Identification of SGMS2 as a molecule involved in natural killer cell recruitment and its in‐deep analysis in the liver cancer microenvironment: Evidence from large populations cohort

Tang, W., Meng, F., Li, M., Li, Y., Xiong, W., Zhang, D., & Yang, B. (2023) · The Journal of Gene Medicine · doi:10.1002/jgm.3609 · Cited by 3

The metabolic drivers of IFN-γ release: glycolysis and acetyl CoA ride in the front seat

Henderson, J., & O’Reilly, S. (2025) · The Journal of Immunology · doi:10.1093/jimmun/vkaf045 · Cited by 4

Sterol Regulatory Element Binding Proteins; Central Metabolic Regulators of Natural Killer Cells

O'brien, K. (2020) · Arrow@dit (Dublin Institute of Technology)

Amino acid-dependant mTORC1 and cMyc signaling is essential for Natural Killer cell metabolic and functional responses

Loftus, R. M. (2017) · Trinity's Access to Research Output (TARA) (Trinity College Dublin)

Cytokine-driven role of Srebps in killer cell metabolism

Guillerey, C., & Smyth, M. J. (2017) · Nature Immunology · doi:10.1038/ni.3855

De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells

O’Brien, K., Aßmann, N., O’Connor, É., Keane, C., Walls, J. F., Choi, C., Oefner, P. J., Gardiner, C. M., Dettmer, K., & Finlay, D. K. (2020) · European Journal of Immunology · doi:10.1002/eji.202048784 · Cited by 33

De novo polyamine synthesis supports metabolic and functional responses in activated murine Natural Killer cells

O’Brien, K., Aßmann, N., O'Connor, E., Keane, C., Walls, J., Choi, C., Oefner, P. J., Gardiner, C. M., Dettmer, K., & Finlay, D. K. (2020) · University of Regensburg Publication Server (University of Regensburg)