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Galectin-3 Regulates γ-Herpesvirus Specific CD8 T Cell Immunity

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Tolerogenic Dendritic Cells in the Control of Autoimmune Neuroinflammation: An Emerging Role of Protein-Glycan Interactions

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Increased Sensitivity of CD4+ T-Effector Cells to CD4+CD25+ Treg Suppression Compensates for Reduced Treg Number in Asymptomatic HIV-1 Infection

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Genetic assessment of the importance of galectin-3 in cancer initiation, progression, and dissemination in mice

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Lack of galectin-3 increases Jagged1/Notch activation in bone marrow-derived dendritic cells and promotes dysregulation of T helper cell polarization

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An Integrated Computational Analysis of the Structure, Dynamics, and Ligand Binding Interactions of the Human Galectin Network

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Analysis of differential expression of glycosyltransferases in healing corneas by glycogene microarrays

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Endogenous Galectin-1 in T Lymphocytes Regulates Anti-prostate Cancer Immunity

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Toll-Like Receptor 4 Promotes Th17 Lymphocyte Infiltration Via CCL25/CCR9 in Pathogenesis of Experimental Autoimmune Encephalomyelitis

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Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand

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Glycoimmunology: ignore at your peril!

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Altered Glycosylation Contributes to Placental Dysfunction Upon Early Disruption of the NK Cell-DC Dynamics

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Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis

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Combining inhibition of galectin-3 with and before a therapeutic vaccination is critical for the prostate-tumor-free outcome

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Sweet Immune Checkpoint Targets to Enhance T Cell Therapy

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Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma

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CD45-Mediated Fodrin Cleavage during Galectin-1 T Cell Death Promotes Phagocytic Clearance of Dying Cells

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DC expressing transgene Foxp3 are regulatory APC

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Dysregulated Immunity in Pulmonary Hypertension: From Companion to Composer

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Manipulating Cell Surface Glycoproteins by Targeting N-Glycan–Galectin Interactions

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Integration of lectin–glycan recognition systems and immune cell networks in CNS inflammation

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Tumor Immune Escape Mechanisms that Operate During Metastasis

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Genome‐wide gene expression profiling reveals unsuspected molecular alterations in pemphigus foliaceus

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Concerted mass spectrometry-based glycomic approach for precision mapping of sulfo sialylated N-glycans on human peripheral blood mononuclear cells and lymphocytes

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Elevated Galectin-10 Expression of IL-22-Producing T Cells in Patients with Atopic Dermatitis

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The sweet and the bitter sides of galectin-1 in immunity: its role in immune cell functions, apoptosis, and immunotherapies for cancer with a focus on T cells

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Galectin‐1 is essential for the induction of MOG35–55‐based intravenous tolerance in experimental autoimmune encephalomyelitis

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BRAF inhibition curtails IFN‐gamma‐inducible PD‐L1 expression and upregulates the immunoregulatory protein galectin‐1 in melanoma cells

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Resident and elicited murine macrophages differ in expression of their glycomes and glycan-binding proteins

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Tissue-specific control of galectin-1-driven circuits during inflammatory responses

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Medawar’s PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation

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Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: Mechanisms and biomedical applications

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Galatrox is a C-type lectin in Bothrops atrox snake venom that selectively binds LacNAc-terminated glycans and can induce acute inflammation

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Arene–Anion Based Arginine‐Binding Motif on a Galactose Scaffold: Structure–Activity Relationships of Interactions with Arginine‐Rich Galectins

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Galectin-1 and immunotherapy for brain cancer

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Critical Role of the Solvent Environment in Galectin-1 Binding to the Disaccharide Lactose

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Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature

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Galectin-1 is a local but not systemic immunomodulatory factor in mesenchymal stromal cells

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Galectin-1 reduced the effect of LPS on the IL-6 production in decidual cells by inhibiting LPS on the stimulation of IκBζ

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Comprehensive characterization of early-programmed tumor microenvironment by tumor-associated macrophages reveals galectin-1 as an immune modulatory target in breast cancer

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Inflammation Controls Sensitivity of Human and Mouse Intestinal Epithelial Cells to Galectin-1

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Galectin-1 is associated with poor prognosis in patients with cutaneous head and neck cancer with perineural spread

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Fine-Tuning Antitumor Responses Through the Control of Galectin–Glycan Interactions: An Overview

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Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle

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Possible novel biomarkers of organ involvement in systemic lupus erythematosus

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Serum galectin-1 in patients with multiple myeloma: associations with survival, angiogenesis, and biomarkers of macrophage activation

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Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB)

Blois, S. M., Verlohren, S., Wu, G., Clark, G. F., Dell, A., Haslam, S. M., & Barrientos, G. (2020) · Seminars in Immunopathology · doi:10.1007/s00281-020-00801-4 · Cited by 22

Validation of galectin-1 as potential diagnostic biomarker of early rheumatoid arthritis

Triguero‐Martínez, A., de la Fuente, H., Montes, N. G., Ortiz, A. M., Roy‐Vallejo, E., Castañeda, S., González‐Álvaro, I., & Lamana, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-74185-8 · Cited by 22

Unraveling How Tumor-Derived Galectins Contribute to Anti-Cancer Immunity Failure

Laderach, D. J., & Compagno, D. (2021) · Cancers · doi:10.3390/cancers13184529 · Cited by 22

Mesenchymal Stem Cells Attenuate Sepsis-associated Acute Kidney Injury by Changing the Balance of Th17 cells/Tregs via Gal-9/Tim-3

Luo, C., Luo, F., Man, X., Liu, X., Zhao, L., Che, L., Zhang, W., Guo, J., Cai, S., Wang, D., et al. (2022) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x17666220511151343 · Cited by 22

Chemoenzymatic Measurement of LacNAc in Single-Cell Multiomics Reveals It as a Cell-Surface Indicator of Glycolytic Activity of CD8+ T Cells

Yu, W., Zhao, X., Jalloh, A. S., Li, Y., Zhao, Y., Dinner, B., Yang, Y., Ouyang, S., Tian, T., Zhao, Z., et al. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c02602 · Cited by 21

Galectokines: The Promiscuous Relationship between Galectins and Cytokines

Sanjurjo, L., Broekhuizen, E. C., Koenen, R. R., & Thijssen, V. L. (2022) · Biomolecules · doi:10.3390/biom12091286 · Cited by 21

Redox state influence on human galectin-1 function

Yu, X., Scott, S. A., Pritchard, R., Houston, T. A., Ralph, S. J., & Blanchard, H. (2015) · Biochimie · doi:10.1016/j.biochi.2015.06.013 · Cited by 21

Targeting of T/Tn Antigens with a Plant Lectin to Kill Human Leukemia Cells by Photochemotherapy

Poiroux, G., Pitié, M., Culerrier, R. M., Lafont, É., Ségui, B., Damme, E. J. M. V., Peumans, W. J., Bernadou, J., Levade, T., Rougé, P., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023315 · Cited by 21

Galectin-1 Markedly Reduces the Incidence of Resorptions in Mice Missing Immunophilin FKBP52

Hirota, Y., Burnum-Johnson, K., Acar, N., Rabinovich, G. A., Daikoku, T., & Dey, S. K. (2012) · Endocrinology · doi:10.1210/en.2012-1035 · Cited by 21

Galectins as therapeutic targets for hematological malignancies: a hopeful sweetness.

Peña, C., Mirandola, L., Figueroa, J. A., Hosiriluck, N., Suvorava, N., Trotter, K., Reidy, A., Rakhshanda, R., Payne, D., Jenkins, M., et al. (2014) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2305-5839.2014.09.14 · Cited by 21

Immunological tolerance induced by galectin-1 in rat allogeneic renal transplantation

Xu, G., Tu, W., & Xu, C. (2010) · International Immunopharmacology · doi:10.1016/j.intimp.2010.03.001 · Cited by 21

Activation of human naïve Th cells increases surface expression of GD3 and induces neoexpression of GD2 that colocalize with TCR clusters

Villanueva-Cabello, T. M., Mollicone, R., Muñoz, M. E. C., López-Guerrero, D. V., & Martínez-Duncker, I. (2015) · Glycobiology · doi:10.1093/glycob/cwv062 · Cited by 21

Belief and contextual acceptance

Cresto, E. (2009) · Synthese · doi:10.1007/s11229-009-9637-2 · Cited by 20

Glycosylation of solute carriers: mechanisms and functional consequences

Borbye‐Lorenzen, N., Carlsson, M. C., & Pedersen, S. F. (2015) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-015-1730-4 · Cited by 21

Graves’ Disease Is Associated with a Defective Expression of the Immune Regulatory Molecule Galectin-9 in Antigen-Presenting Dendritic Cells

Leskelä, S., Serrano, A. M., de la Fuente, H., Rodríguez‐Muñoz, A., Ramos-Levi, A. M., Sampedro-Nuñez, M. A., Sánchez‐Madrid, F., González‐Amaro, R., & Marazuela, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123938 · Cited by 20

The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine

Muglia, C. I., Mercer, N., Toscano, M. A., Schattner, M. A., Pozner, R., Cerliani, J. P., Gobbi, R. P., Rabinovich, G. A., & Docena, G. H. (2011) · Cell Death and Disease · doi:10.1038/cddis.2011.44 · Cited by 20

CD43 – One molecule, many tales to recount

Pedraza‐Alva, G., & Rosenstein, Y. (2007) · Signal Transduction · doi:10.1002/sita.200700140 · Cited by 20

Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro

Dickhout, A., Tullemans, B. M. E., Heemskerk, J. W. M., Thijssen, V. L., Kuijpers, M. J. E., & Koenen, R. R. (2021) · PLoS ONE · doi:10.1371/journal.pone.0244736 · Cited by 20

Linking the Structure and Thermal Stability of β-Galactoside-Binding Protein Galectin-1 to Ligand Binding and Dimerization Equilibria

Lella, S. D., Marti, M. A., Croci, D. O., Guardia, C. M. A., Ricci, J. C. D., Rabinovich, G. A., Caramelo, J. J., & Estrin, D. A. (2010) · Biochemistry · doi:10.1021/bi100356g · Cited by 19

Neuroinflammation induced by amyloid β25–35 modifies mucin-type O -glycosylation in the rat's hippocampus

Ramos-Martínez, I. E., Loustalot, P. M., Lozano, L., Issad, T., Limón, I. D., Díaz, A., Pérez‐Torres, A., Guevara, J., & Zenteno, E. (2017) · Neuropeptides · doi:10.1016/j.npep.2017.11.008 · Cited by 19

Galectin-1 Expression in CD8+ T Lymphocytes Controls Inflammation in Contact Hypersensitivity

Castillo‐González, R., Cibrián, D., Fernández‐Gallego, N., Ramírez‐Huesca, M., Sáiz, M. L., Navarro, M. N., Fresno, M., de la Fuente, H., & Sánchez‐Madrid, F. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.10.020 · Cited by 19

Hyposialylation Must Be Considered to Develop Future Therapies in Autoimmune Diseases

Bordron, A., Morel, M., Bagacean, C., Dueymes, M., Pochard, P., Harduin‐Lepers, A., Jamin, C., & Pers, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073402 · Cited by 19

Galectin-3 expression in response to LPS, immunomodulatory drugs and exogenously added galectin-3 in monocyte-like THP-1 cells

Dabelić, S., Novak, R., Goreta, S. Š., & Dumić, J. (2012) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-012-9540-x · Cited by 19

A chimeric, multivalent assembly of galectin-1 and galectin-3 with enhanced extracellular activity

Fettis, M. M., Farhadi, S. A., & Hudalla, G. A. (2019) · Biomaterials Science · doi:10.1039/c8bm01631c · Cited by 19

ABO blood groups and galectins: Implications in transfusion medicine and innate immunity

Arthur, C. M., Hollenhorst, M. A., Wu, S., Jajosky, R. P., Nakahara, H., Jan, H.-M., Zheng, L., Covington, M. L., Rakoff-Nahoum, S., Yeung, M. Y., et al. (2024) · Seminars in Immunology · doi:10.1016/j.smim.2024.101892 · Cited by 18

In Brief

(2007) · Nature reviews. Immunology · doi:10.1038/nri2149

Galectin‐1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function

Motrán, C. C., Molinder, K. M., Liu, S. D., Poirier, F., & Miceli, M. C. (2008) · European Journal of Immunology · doi:10.1002/eji.200838295 · Cited by 108

Galectin-1 Binds Different CD43 Glycoforms to Cluster CD43 and Regulate T Cell Death

Hernandez, J. D., Nguyen, J. T., He, J., Wang, W., Ardman, B. M., Green, J. M., Fukuda, M., & Baum, L. G. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.8.5328 · Cited by 128

Regulated glycosylation controls the fate and function of regulatory T cells

Santiago, M.-H., Tomas, D.-M., Diego, C. R., Juan, C., Karina, M., Marta, T., & Gabriel, R. (2015) · Frontiers in Immunology · doi:10.3389/conf.fimmu.2015.05.00204

Dimeric galectin-1 alters the plasticity and commitment of Th1 and Th17 cells by promoting IL-10 expression. (152.20)

Cedeno‐Laurent, F., Opperman, M. J., Barthel, S. R., & Dimitroff, C. J. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.186.supp.152.20 · Cited by 1