Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Fontenot, J. D., Gavin, M. A., & Rudensky, A. Y. (2003) · Nature Immunology · doi:10.1038/ni904 · Cited by 7,745

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

Chen, W., Jin, W., Hardegen, N. J., Lei, K.-J., Li, L., Marinos, N. J., McGrady, G., & Wahl, S. M. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030152 · Cited by 4,678

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M., Ferguson, P., Whitesell, L., Kelly, T., Saulsbury, F., Chance, P., & Ochs, H. (2001) · Nature Genetics · doi:10.1038/83713 · Cited by 3,576

N aturally A rising CD4+R egulatory T C ells for I mmunologic S elf -T olerance and N egative C ontrol of I mmune R esponses

Sakaguchi, S. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141122 · Cited by 3,315

An essential role for Scurfin in CD4+CD25+ T regulatory cells

Khattri, R., Cox, T., Yasayko, S.-A., & Ramsdell, F. (2003) · Nature Immunology · doi:10.1038/ni909 · Cited by 2,860

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A., Paeper, B. W., Clark, L. B., Yasayko, S.-A., Wilkinson, J. E., Galas, D. J., Ziegler, S. F., & Ramsdell, F. (2001) · Nature Genetics · doi:10.1038/83784 · Cited by 2,628

Smad transcription factorsPreprint

Massagué, J., Seoane, J., & Wotton, D. (2005) · Genes & Development · doi:10.1101/gad.1350705 · Cited by 2,519

Regulatory T cells, tumour immunity and immunotherapy

Zou, W. (2006) · Nature reviews. Immunology · doi:10.1038/nri1806 · Cited by 2,135

Leptina: um modulador central das respostas imunes.

Moraes‐Vieira, P. M. (2011) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2011.tde-09022012-141522

Untersuchung der molekularen Mechanismen der T-Zell Modulation bei der Therapie mit gering dosiertem Cyclosporin A in Patienten mit atopischer Dermatitis

Brandt, C. (2011) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-10055

Regulation of calcium signaling and cellular localization of NFAT in CD8+ anergic T cells.

Srinivasan, M. (2008) · University Libraries (University of Maryland)

Regulation und funktionelle Rolle des murinen Transkriptionsfaktors Foxp3 in T-Zellen

Freyer, J. (2008) · edoc Publication server (Humboldt University of Berlin) · doi:10.18452/15841

Application of Regulatory T Cells in Transplantation Field

Kim, Y.-H., Kim, H. J., Kim, J.-S., & Park, C. (2012) · Korean Journal of Transplantation · doi:10.4285/jkstn.2012.26.2.74

The Roles of Immune Regulatory Factors FoxP3, PD-1, and CTLA-4 in Chronic Viral Infection

Cho, H. (2013) · The Korean Journal of Microbiology · doi:10.7845/kjm.2013.3049

In vitro generation of human FOXP3+ regulatory T cells

Abdulrasool, G. A. E. S. (2014) · UPT. Syiah Kuala University Library (Syiah Kuala University)

Role of Smad and non-Smad Signals in the Development of Th17 and Regulatory T Cells

Zheng, S. G., Lu, L., Wang, J., Zhang, F., Brand, D. D., Horwitz, D. A., Wang, X., & Shi, W. (2010) · Clinical Immunology · doi:10.1016/j.clim.2010.03.209

Signals Controlling Regulatory T Cell Differentiation and Homeostasis

Zou, T. (2012) · ScholarlyCommons (University of Pennsylvania)

Untersuchung der Expression und Translokation von Transkriptionsfaktoren bei der Aktivierung von T-Helfer- und regulatorischen T-Zellen

Bendfeldt, H. (2010) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-16736

Effector and Regulatory CD4 T Cells During Mycobacterium tuberculosis Infection

Green, A. M. (2010) · D-Scholarship@Pitt (University of Pittsburgh)

Transcriptional control of CD4+ T lymphocytes

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Regulatory T Cell Development from the Top Down: the Role of T Cell Receptor-Generated Second Messengers in Thymic Regulatory T Cell Development

Kambayashi, T., & Schmidt, A. M. (2014)

Natural occurring regulatory T cells: role of transcription factor FOXP3 and new approaches improving Treg-cell based therapy

Fanelli, G. (2013) · IRIS Research product catalog (Sapienza University of Rome)

Novel aspects of TGFβ in human CD4 + T cell biology

Bonn, R. F.-W.-U. (2008)

The role of regulatory T and B cells in host responses to Chlamydia genital tract infection

Moore-Connors, J. (2016) · DalSpace (Dalhousie University)

FOXP3 and CTLA-4 : how isoforms regulate immunological tolerance

Liu, S. (2015) · Figshare

SA-4-1BBL as a modulator of T effector to T regulatory cell conversion.

Madireddi, S. (2010) · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville) · doi:10.18297/etd/880

Participação de celulas T regulatorias (CD4+CD25+) na imunossupressão observada em pacientes com paracoccidioidomicose

Ferreira, M. C. (2009) · doi:10.47749/t/unicamp.2009.440430

Pathway To Drive Th17 Differentiation Induction of the Nuclear Orphan Receptor Calcium Signaling via Orai1 Is Essential for

Gwack, Y., Ribalet, B., Jew, M., Damoiseaux, R. D., Jung, M. E., Kim, K., & Srikanth, S. (2014)

Trigona Honey, a Natural Bee Product Promotes mRNA Foxp3 Expression in Healthy in Mice Balb/c Strain

Usman, A. N., Hatta, M., Natsir, R., Rahardjo, S. P., Widaningsih, Y., Syam, Y., Ainurrafiq, Lestari, H., & Bahar, H. (2016) · International Journal of Sciences: Basic and Applied Research

Thymic involution perturbs negative selection and leads to chronic inflammation

Coder, B. (2015) · Digital Commons @ UNT Health Science Center

Post-translational regulation of FOXP3

Coffer, P. J., Prakken, A. B. J., & van Loosdregt, J. (2006)

The involvement of IRAK-1 in the regulation of NFATc2 in T cells

Zhang, L. (2008) · VTechWorks (Virginia Tech)

Reproductive Benefits Conferred by Genetically Foreign Cells that Persist in Mothers and Offspring

Kinder, J. M. (2016) · OhioLink ETD Center (Ohio Library and Information Network)

The Importance of Controlling the TGF-β Signaling Pathway in the Gastric Cancer MicroenvironmentPreprint

Kinoshita, J., Fushida, S., & Ohta, T. (2017) · Preprints.org · doi:10.20944/preprints201707.0035.v1

Cytokines From Mesenchymal Stem Cells Induce Immunosuppressive Cells

Kyurkchiev, D. S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804214-4.00014-2

FOXP3+ Treg Cells and Systems Biology Approaches to Studying Their Function

Luo, X., Tsun, A., Yang, J. C., Chen, Z., Gao, Y., Li, K., Piccioni, M., & Li, B. (2015) · Translational bioinformatics · doi:10.1007/978-94-017-9753-5_6

Rôle des facteurs de transcription Eos et Helios dans la biologie des cellules T régulatrices

Polak, K. (2015) · theses.fr (ABES) · doi:10.70675/a05cabbezdb21z40e5zb964zce0e8c751cf4

Characterization of the immunoregulatory roles of IFN-β in T cells and dendritic cells

Pennell, L. M. (2017) · TSpace (University of Toronto)

Etude de la régulation lymphocytaire T dans deux modèles de transplantation rénale et pulmonaire

Durand, M. (2018) · theses.fr (ABES) · doi:10.70675/9bab08c2z2a10z4e8bz870fz72da9d29a92d

Peripheral immune cell abnormalities associated with cystic fibrosis

Mulcahy, E. M. (2017) · UTAS Research Repository · doi:10.25959/23210792

TGF-BETA1/SMAD3 SUPPRESS ANTI-TUMOR IMMUNITY BY ENHANCING PD-1 EXPRESSION ON ANTIGEN-SPECIFIC CD8+ T CELLS IN CANCER

Park, B. V. (2015)

Molecular mechanisms of differential activation of naive T cells by weak and strong antigen-presenting cells

Etemire, E. (2013)

Ρυθμιστικά Τ-κύτταρα και επαγόμενη από απόπτωση φλεγμονή

Αργέντου, Ν. (2014) · doi:10.12681/eadd/40837

Análise do papel da subunidade c-Rel durante a geração in vitro de células T regulatórias induzidas a partir de células T naive de sangue de cordão umbilical

Leão, V. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2019.tde-03062019-155201

Transcriptional control of tissue-resident memory T cell generation

Cvetkovski, F. (2019) · doi:10.7916/d8-n16c-b343

Influence des interactions avec le Soi sur le devenir des cellules T CD4 naïves en phase effectrice

Guichard, V. (2019) · theses.fr (ABES) · doi:10.70675/06681aaazd652z46c7zb83ez63059bc91f52

Nuclear NFATc1/Smad3 complexes in Smad4-deficient pancreatic cancer

Hasselluhn, M. C. (2019) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-7778

Molecular Regulation of SATB1 in Regulatory T-cells

Thabet, Y. (2013) · bonndoc (University of Bonn)

Development of thymic regulatory T cells during human immunodeficiency virus (HIV) infection

Swaminathan, S. (2019) · Archipel (Université du Québec à Montréal)

Pten Signaling in Regulatory T Cells and Inflammatory Disease

Shrestha, S. (2016) · doi:10.21007/etd.cghs.2016.0400

Regulatory T Cells: Promises and Challenges

Alhaddad, J. B., Melhem, G., Allos, H., & Azzi, J. R. (2020) · Current Transplantation Reports · doi:10.1007/s40472-020-00292-0

IL-33 regulates age-dependency of long-term immune dysfunction induced by sepsisPreprint

Colón, D. F., Wanderley, C. W. S., Turato, W. M., Borges, V. F., Franchin, M., Castanheira, F. V. S., Nascimento, D., Prado, D. D. S., de Lima, M. H. F., Volpon, L. C., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.15.476447

Correction: SMAD3 rs17228212 Gene Polymorphism Is Associated with Reduced Risk to Cerebrovascular Accidents and Subclinical Atherosclerosis in Anti-CCP Negative Spanish Rheumatoid Arthritis Patients

García-BermÃodez, M., pez-Mejías, R. L., Genre, F., Castañeda, S., González-Juanatey, C., Llorca, J., Corrales, A., Miranda-Filloy, J. A., Rueda‐Gotor, J., Gómez‐Vaquero, C., et al. (2013) · PLoS ONE · doi:10.1371/annotation/3fc037c1-2585-4d2b-a781-e04ab7b3bfeb

Immune System

Feske, S. (2011) · Springer eBooks · doi:10.1007/978-3-7091-0962-5_19

Faculty Opinions recommendation of Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance.

Saas, P., & Perruche, S. (2013) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717996342.793474769

Importância da proteína quinase ativada por AMP (AMPK) na regulação da sinalização do TGF-β e diferenciação das células T reguladoras

Hernandez, C. A. S. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2021.tde-11042022-103824

Analysis of Lymphocytes with T regulatory Phenotype in Kidney Allografts of Saint-Petersburg

Kara, T. (2018) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-6654

TGFβ

Akdiş, C. A., & Wanke, K. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-374279-7.10016-5

Faculty Opinions recommendation of The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.

Mapara, M. Y., & Lu, C. (2010) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.5667958.5640057

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Transcriptomic Profiling and Regulatory Network Reconstruction Uncovers Central Genes in HTLV Infection Progression

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Mechanisms and Regulation of Transforming Growth Factor Superfamily Mediated Gene Expression.

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Self-tolerance in collagen induced arthritis

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Identification of Novel Signaling Pathways in T Cells Mediated by Protein Kinase C, Carma1, MALT1 and Bcl10

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Regulation of Type II Responses in Lung Fibrosis and Systemic Autoimmunity: A Dissertation

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Additional file 1 of The construction, expression, and enhanced anti-tumor activity of YM101: a bispecific antibody simultaneously targeting TGF-β and PD-L1

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Additional file 1 of Regulatory role of PI16 in autoimmune arthritis and intestinal inflammation: implications for Treg cell differentiation and function

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In-depth characterization of early stages of human induced regulatory T cell differentiation by mass cytometry

Kattelus, R. (2022) · UTUPub (University of Turku)

The role of high-density lipoproteins in the activation of T lymphocytes and regulation of immune response

das Neves, M. F. (2022) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)

The influence of stromal fibroblast on antigen-presenting cell \nfunction and alteration of their biology

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Investigation of immune quiescence: assessing the role of regulatory T cells and their link with IRF-1 in HIV-exposed sero-negative individuals

Abdullahi, A. (2016) · Mspace (University of Manitoba)

Small Extracellular Vesicles from Porous Templated Scaffold Resident Cells Modulate CD4+ T Cell Subsets that Promote a Pro-Healing Host Response

Hady, T. (2022) · ResearchWorks at the University of Washington (University of Washington)

SAICAR Drives T Regulatory Cell Differentiation and FOXP3 Maintenance to Promote Immunotherapy Resistance

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Single-cell transcriptomics reveals targeted modulation of inflammatory repertoire by SOCE blockers

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The role of glucocorticoid hormone in the differentiation of regulatory T cells

Ramóna, P. (2023) · Pesci Egyetemi Archivum (University of Pécs)

Therapeutic effects of TGT-β induced regulatory T cells on the established autoimmune and inflammatory diseases

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TRPM4, a non selective cation-permeable channel regulates Foxp3+ regulatory T cells suppressive function and survival trough modulating calcium influx

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Modulations nutritionnelles de la réponse à l'infection pulmonaire à P. aeruginosa dans différents fonds génétiques murins

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Modulation des voies de présentation antigénique et induction de lymphocytes T régulateurs pour la thérapie génique

Carpentier, M. (2013) · theses.fr (ABES) · doi:10.70675/fa69ca30zf46az45f1z9638z003bd41555e4

CD103 : du gène à la protéine : Etude de la régulation et de la signalisation de l’intégrine αE(CD103)β7 exprimée par les lymphocytes T CD8+ intratumoraux

Mokrani, M. (2013) · theses.fr (ABES) · doi:10.70675/7d6d8c31z6306z4acez8ff0z9918ea96a350

Lymphocytes T et vieillissement : lymphopénie ou redistribution ?

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Impact des inhibiteurs de la voie mTOR sur la réponse immunitaire T anti-tumorale

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Immunothérapie par faibles doses d'IL-2 : potentiel therapeutique dans le diabète de type 1

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Induction de tolérance en transplantation hépatique par l'utilisation d'un traitement retardé a la rapamycine

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What turns on Foxp3?

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Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut

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Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I

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TGF-β–Mediated Foxp3 Gene Expression Is Cooperatively Regulated by Stat5, Creb, and AP-1 through CNS2

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