Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

Németh, Krisztián, Leelahavanichkul, Asada, Yuen, Peter S T, Mayer, Balázs, Parmelee, Alissa, Doi, Kent, Robey, Pamela G, Leelahavanichkul, Kantima +6 more·2009·Nature Medicine

DOI 10.1038/nm.1905

Cited by (1,003)

Items 701–800 of 1,003

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Lucia Zanotti, Roberta Angioni, Bianca Calì, Cristiana Soldani, Cristina Ploia, Federica Moalli, Madhusudhana Gargesha, Giovanna D’Amico, Stephen J. Elliman, Gabriella Tedeschi et al. · 2016 · Leukemia
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Jingman Li, Yuchen Pan, Jingjing Yang, Jiali Wang, Qi Jiang, Huan Dou, Yayi Hou · 2022 · Frontiers in Immunology
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Concise Review: The Bystander Effect: Mesenchymal Stem Cell-Mediated Lung Repair
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Hongshan Zhang, Jian-Pei Fang, Haobin Su, Min Yang, Wenyu Lai, Yougang Mai, Yanyun Wu · 2012 · Pediatric Transplantation
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Katsuyuki Takeda, Tracy L. Webb, Fangkun Ning, Yoshiki Shiraishi, Daniel P. Regan, Lyndah Chow, Mia J. Smith, Shigeru Ashino, Amanda Guth, Sophie Hopkins et al. · 2018 · The Journal of Immunology
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Lee, Chien-Hsun, Yeh, Tzu-Hao, Lai, Hsiao-Ching, Wu, Shih-Yi, Su, Ih-Jen, Takada, Kenzo, Chang, Yao · 2011 · Journal of Virology
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