Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

Németh, Krisztián, Leelahavanichkul, Asada, Yuen, Peter S T, Mayer, Balázs, Parmelee, Alissa, Doi, Kent, Robey, Pamela G, Leelahavanichkul, Kantima +6 more·2009·Nature Medicine

DOI 10.1038/nm.1905

Cited by (1,003)

Items 101–200 of 1,003

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Xiaohong Wang, Haitao Gu, Dongze Qin, Liwang Yang, Wei Chieh Huang, Kobina Essandoh, Yigang Wang, Charles C. Caldwell, Tianqing Peng, Basilia Zingarelli et al. · 2015 · Scientific Reports
Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes
Anna D. Krasnodembskaya, Gianluca Samarani, Yuanlin Song, Hanjing Zhuo, Xiao Su, Jae Wook Lee, Naveen Gupta, Mario Petrini, Michael A. Matthay · 2012 · American Journal of Physiology-Lung Cellular and Molecular Physiology
MSC-secreted TGF-β regulates lipopolysaccharide-stimulated macrophage M2-like polarization via the Akt/FoxO1 pathway
Feng Liu, Haibo Qiu, Ming Xue, Shi Zhang, Xiwen Zhang, Jingyuan Xu, Jianxiao Chen, Yi Yang, Jianfeng Xie · 2019 · Stem Cell Research & Therapy
Mesenchymal stem cells enhance survival and bacterial clearance in murineEscherichia colipneumonia
Naveen Gupta, Anna D. Krasnodembskaya, Maria G. Kapetanaki, Majd Mouded, Xinping Tan, Vladimir B. Serikov, Michael A. Matthay · 2012 · Thorax
Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis
Neil H Riordan, Thomas E. Ichim, Wei‐Ping Min, Hao Wang, Fabio Solano, Fabian Lara, Miguel A. Alfaro, Jorge Paz Rodríguez, Robert J. Harman, Amit N. Patel et al. · 2009 · Journal of Translational Medicine
Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action
Lavinia Ionescu, Roisin Byrne, Tim van Haaften, Arul Vadivel, Rajesh S. Alphonse, G Rey-Parra, Gaia Weissmann, Adam Hall, Farah Eaton, Bernard Thébaud · 2012 · American Journal of Physiology-Lung Cellular and Molecular Physiology
Mesenchymal stem cell therapy for the treatment of inflammatory diseases: Challenges, opportunities, and future perspectives
Shobha Regmi, Shiva Pathak, Jong Oh Kim, Chul Soon Yong, Jee‐Heon Jeong · 2019 · European Journal of Cell Biology
Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases
Farida Djouad, Carine Bouffi, Soufiane Ghannam, Danièle Noël, Christian Jørgensen · 2009 · Nature Reviews Rheumatology
Dental mesenchymal stem cells
Paul Thomas Sharpe · 2016 · Development
Stem Cells and Cell Therapies in Lung Biology and Lung Diseases
Daniel J. Weiss, Jay K. Kolls, Luis A. Ortiz, Angela Panoskaltsis‐Mortari, Darwin J. Prockop · 2008 · Proceedings of the American Thoracic Society
Therapeutic Applications of Mesenchymal Stromal Cells: Paracrine Effects and Potential Improvements
Joyce Doorn, Guido Moll, Katarina Le Blanc, Clemens van Blitterswijk, Jan de Boer · 2011 · Tissue Engineering Part B Reviews
Concise Review: Mesenchymal Stem Cells and Translational Medicine: Emerging Issues
Guangwen Ren, Xiaodong Chen, Fengping Dong, Wenzhao Li, Xiaohui Ren, Yi Zhang, Yufang Shi · 2011 · Stem Cells Translational Medicine
Mesenchymal Stromal Cells: Facilitators of Successful Transplantation?
Karen English, Anna French, Kathryn J. Wood · 2010 · Cell stem cell
Mesenchymal stem cells: Immunomodulatory capability and clinical potential in immune diseases
Qinjun Zhao, Hongying Ren, Zhongchao Han · 2015 · Journal of Cellular Immunotherapy
The Immunomodulatory Functions of Mesenchymal Stromal/Stem Cells Mediated via Paracrine Activity
Zhou, Yueyuan, Yamamoto, Yusuke, Xiao, Zhongdang, Ochiya, Takahiro · 2019 · Journal of Clinical Medicine
Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives
Carl Randall Harrell, Bojana Simović Marković, Crissy Fellabaum, Aleksandar Arsenijević, Vladislav Volarević · 2018 · Biomedicine & Pharmacotherapy
Comparing the Immunomodulatory Properties of Bone Marrow, Adipose Tissue, and Birth-Associated Tissue Mesenchymal Stromal Cells
Philipp Mattar, Karen Bieback · 2015 · Frontiers in Immunology
Cytokine Modulation of TLR Expression and Activation in Mesenchymal Stromal Cells Leads to a Proinflammatory Phenotype
Raphaëlle Romieu, Moïra François, Marie‐Noëlle Boivin, Manaf Bouchentouf, David Spaner, Jacques Galipeau · 2009 · The Journal of Immunology
Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α
Diarmaid D. Houlihan, Yo Mabuchi, Satoru Morikawa, Kunimichi Niibe, Daisuke Araki, Sadafumi Suzuki, Hideyuki Okano, Yumi Matsuzaki · 2012 · Nature Protocols
Antimicrobial Activity of Mesenchymal Stem Cells: Current Status and New Perspectives of Antimicrobial Peptide-Based Therapies
Francisca Alcayaga‐Miranda, Jimena Cuenca, Maroun Khoury · 2017 · Frontiers in Immunology
Macrophage Related Chronic Inflammation in Non-Healing Wounds
Meirong Li, Qian Hou, Lingzhi Zhong, Yali Zhao, Xiaobing Fu · 2021 · Frontiers in Immunology
Immunological Aspects of Allogeneic Mesenchymal Stem Cell Therapies
Matthew Dallas Griffin, Thomas Ritter, Bernard P. Mahon · 2010 · Human Gene Therapy
Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat
Gerard F. Curley, Mairéad Hayes, Bilal Ansari, Georgina Shaw, Aideen E. Ryan, Frank Barry, Timothy O’Brien, Daniel P. O’Toole, John Gerard Laffey · 2011 · Thorax
The Role of the Immune Cells in Fracture Healing
Baht, Gurpreet S., Vi, Linda, Alman, Benjamin A. · 2018 · Current Osteoporosis Reports
Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis
James McCauley Walter, Lorraine B. Ware, Michael A. Matthay · 2014 · The Lancet Respiratory Medicine
Mesenchymal stem cell therapy for attenuation of scar formation during wound healing
Wesley M. Jackson, Leon J. Nesti, Rocky S. Tuan · 2012 · Stem Cell Research & Therapy
Trophic Effects of Mesenchymal Stem Cells in Tissue Regeneration
Yao Fu, Lisanne Karbaat, Ling Wu, Jeroen Leijten, Sanne K. Both, Marcel Karperien · 2017 · Tissue Engineering Part B Reviews
Mesenchymal Stem Cell-Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation
Luz-Crawford, Patricia, Djouad, Farida, Toupet, Karine, Bony, Claire, Franquesa, Marcella, Hoogduijn, Martin J., Jorgensen, Christian, Noël, Danièle · 2016 · Stem Cells
Mesenchymal stromal cell apoptosis is required for their therapeutic function
Pang, Swee Heng Milon, D’Rozario, Joshua, Mendonca, Senora, Bhuvan, Tejasvini, Payne, Natalie L., Zheng, Di, Hisana, Assifa, Wallis, Georgia, Barugahare, Adele, Powell, David et al. · 2021 · Nature Communications
Concise Review: Clinical Translation of Wound Healing Therapies Based on Mesenchymal Stem Cells
Wesley M. Jackson, Leon J. Nesti, Rocky S. Tuan · 2011 · Stem Cells Translational Medicine
Macrophage Subpopulations Are Essential for Infarct Repair With and Without Stem Cell Therapy
Tamar Ben-Mordechai, Radka Holbová, Natalie Landa‐Rouben, Tamar Harel-Adar, Micha S. Feinberg, Ihab Abd Elrahman, Galia Blum, Fred H. Epstein, Zmira Silman, Smadar Cohen et al. · 2013 · Journal of the American College of Cardiology
Mesenchymal stromal cells: Putative microenvironmental modulators become cell therapy
Mauro Krampera, Katarina Le Blanc · 2021 · Cell stem cell
Mesenchymal stromal cells and the innate immune response
Katarina Le Blanc, Lindsay C. Davies · 2015 · Immunology Letters
Allogeneic Human Mesenchymal Stem Cells Restore Epithelial Protein Permeability in Cultured Human Alveolar Type II Cells by Secretion of Angiopoietin-1*
Fang, Xiaohui, Neyrinck, Arne P., Matthay, Michael A., Lee, Jae W. · 2010 · Journal of Biological Chemistry
Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications
Wei-Zhan Zhuang, Yi-Heng Lin, Long‐Jyun Su, Meng-Shiue Wu, Han-Yin Jeng, Huan‐Cheng Chang, Yen‐Hua Huang, Thai‐Yen Ling · 2021 · Journal of Biomedical Science
Mesenchymal stem cells for clinical application
Luc Sensebé, Mauro Krampera, Hubert Schrezenmeier, Philippe Bourin, Rosaria Giordano · 2009 · Vox Sanguinis
Clinical results and second‐look arthroscopic findings after treatment with adipose‐derived stem cells for knee osteoarthritis
Yong Gon Koh, Yunjin Choi, Sae-Kwang Kwon, Yong‐Sang Kim, Jee‐Eun Yeo · 2013 · Knee Surgery Sports Traumatology Arthroscopy
Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6
Gavin W. Roddy, Joo Youn Oh, Ryang Hwa Lee, Thomas J. Bartosh, Joni Ylöstalo, Katie Coble, Robert H. Rosa, Darwin J. Prockop · 2011 · Stem Cells
Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction
Ni Su, Peng-Lai Gao, Kai Wang, Jin-Yang Wang, Yi Zhong, Ying Luo · 2017 · Biomaterials
Anti‐donor immune responses elicited by allogeneic mesenchymal stem cells: what have we learned so far?
Matthew Dallas Griffin, Aideen E. Ryan, Senthilkumar Alagesan, Paul Lohan, Oliver Treacy, Thomas Ritter · 2012 · Immunology and Cell Biology
Long term culture of mesenchymal stem cells in hypoxia promotes a genetic program maintaining their undifferentiated and multipotent status
Leticia Basciano, Christophe Némos, B. Foliguet, N. de Isla, Marcelo De Carvalho Bittencourt, Nguyen Tran, Ali H. Dalloul · 2011 · BMC Cell Biology
Mesenchymal Stem Cells: A Friend or Foe in Immune-Mediated Diseases
Marina Gazdic, Vladislav Volarević, Nebojša Arsenijević, Miodrag Stojković · 2015 · Stem Cell Reviews and Reports
Cartilage tissue engineering: From biomaterials and stem cells to osteoarthritis treatments
Claire S. Vinatier, Jérôme Guicheux · 2016 · Annals of Physical and Rehabilitation Medicine
Effects of Mesenchymal Stem Cell‐Derived Paracrine Signals and Their Delivery Strategies
Calvin K.W. Chang, Jerry Yan, Zhi‐Cheng Yao, Chi Zhang, Xiaowei Li, Hai‐Quan Mao · 2021 · Advanced Healthcare Materials
MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus
Shiyu Liu, Dawei Liu, Chider Chen, Kazunori Hamamura, Alireza Moshaverinia, Ruili Yang, Yao Liu, Yan J. Jin, Songtao Shi · 2015 · Cell Metabolism
PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A–SIK–CRTC3 Pathway
Kirsty F. MacKenzie, Kristopher Clark, Shaista Naqvi, Victoria A. McGuire, Gesa Nöehren, Yosua Adi Kristariyanto, Mirjam van den Bosch, Manikhandan Mudaliar, Pierre C. McCarthy, Michael J. Pattison et al. · 2012 · The Journal of Immunology
Immunoregulatory hydrogel decorated with Tannic acid/Ferric ion accelerates diabetic wound healing via regulating Macrophage polarization
Na Xu, Yuanping Gao, Zheng Li, Yu Chen, Menglong Liu, Jiezhi Jia, Rui Zeng, Gaoxing Luo, Jiangfeng Li, Yunlong Yu · 2023 · Chemical Engineering Journal
Monocytes Induce STAT3 Activation in Human Mesenchymal Stem Cells to Promote Osteoblast Formation
Vicky Nicolaidou, Mei Mei Wong, Andia N. Redpath, Adel Ersek, Dilair F. Baban, Lynn M. Williams, Andrew Paul Cope, Nicole J. Horwood · 2012 · PLoS ONE
Mesenchymal Stromal Cells and Cutaneous Wound Healing: A Comprehensive Review of the Background, Role, and Therapeutic Potential
Michael Sung-Min Hu, Mimi Rosealie Borrelli, Hermann Peter Lorenz, Michael Thornton Longaker, Derrick C. Wan · 2018 · Stem Cells International
An Update on the Progress of Isolation, Culture, Storage, and Clinical Application of Human Bone Marrow Mesenchymal Stem/Stromal Cells
Dinh‐Toi Chu, Thuy T. P. Nguyen, Nguyen Le Bao Tien, Tran Dang Khoa, Vo Van Thanh, Thuy Luu Quang, Dang Tien Truong, Van-Huy Pham, Võ Trương Như Ngọc, Thien Chu-Dinh et al. · 2020 · International Journal of Molecular Sciences
Macrophage Polarization and Bone Formation: A review
Nicole J. Horwood · 2015 · Clinical Reviews in Allergy & Immunology
Mesenchymal stem cell inhibition of T‐helper 17 cell‐ differentiation is triggered by cell–cell contact and mediated by prostaglandin E2 via the EP4 receptor
Michelle M. Duffy, Jana Pindjáková, Shirley A. Hanley, Cathal McCarthy, Gudrun A. Weidhofer, Eva Marie Sweeney, Karen English, Georgina Shaw, Mary J. Murphy, Frank Barry et al. · 2011 · European Journal of Immunology
Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy
Pierre Rocheteau, Laurent Châtre, David Briand, Miryam Mebarki, Grégory Jouvion, Jean Bardon, Clément Crochemore, P. Serrani, Pier Paolo Lecci, Mathilde Latil et al. · 2015 · Nature Communications
Mechanisms of Key Innate Immune Cells in Early- and Late-Onset Preeclampsia
Ingrid Aneman, Dillan Pienaar, Sonja R. Suvakov, Tatjana P. Simic, Vesna D. Garovic, Lana McClements · 2020 · Frontiers in Immunology
Human Pericytes for Ischemic Heart Repair
Chien-Wen Chen, Masaho Okada, Jonathan D. Proto, Xueqin Gao, Naosumi Sekiya, Sarah Beckman, Mirko Corselli, Mihaela Crisan, Arman Saparov, Kimimasa Tobita et al. · 2012 · Stem Cells
Concise review: two negative feedback loops place mesenchymal stem/stromal cells at the center of early regulators of inflammation
Prockop, Darwin J. · 2013 · Stem Cells
On the origin of myeloid-derived suppressor cells
Camilla Rydberg Millrud, Caroline Bergenfelz, Karin Leandersson · 2016 · Oncotarget
Immunomodulatory Mechanisms of Mesenchymal Stem Cells and Their Potential Clinical Applications
Yutong Huang, Qiang Wu, Paul Kwong Hang Tam · 2022 · International Journal of Molecular Sciences
Pre-treatment with IL-1β enhances the efficacy of MSC transplantation in DSS-induced colitis
Hongye Fan, Guangfeng Zhao, Liu Liu, Fei Liu, Wei Gong, Xianqin Liu, Liu Yang, Jianjun Wang, Yayi Hou · 2012 · Cellular and Molecular Immunology
Toll-Like Receptor-3-Activated Human Mesenchymal Stromal Cells Significantly Prolong the Survival and Function of Neutrophils
Marco Antonio Cassatella, Federico Mosna, Alessandra Micheletti, Veronica Lisi, Nicola Tamassia, Caterina Cont, Federica Calzetti, Martin Pelletier, Giovanni Pizzolo, Mauro Krampera · 2011 · Stem Cells
Mesenchymal stem cells secrete factors that inhibit inflammatory processes in short-term osteoarthritic synovium and cartilage explant culture.
G. V. van Buul, E. Villafuertes, P. K. Bos, J. Waarsing, N. Kops, R. Narcisi, H. Weinans, J. Verhaar, M. R. Bernsen, G. V. van Osch · 2012 · Osteoarthritis and Cartilage
Pro‐inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX‐2‐prostaglandin E2 pathway
Laura Y. Lu, Florence Loi, Karthik Nathan, Tzu‐Hua Lin, Jukka Pajarinen, Emmanuel Gibon, Akira Nabeshima, Luis A. Córdova, Eemeli Jämsen, Zhenyu Yao et al. · 2017 · Journal of Orthopaedic Research®
Immunomodulatory Properties of Mesenchymal Stromal Cells and Their Therapeutic Consequences for Immune-Mediated Disorders
Senming Zhao, Rebekka Wehner, Martin Bornhäuser, Ralf Waßmuth, Michael Philipp Bachmann, Marc Schmitz · 2009 · Stem Cells and Development
Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion
Gang Chen, Chul‐Kyu Park, Rou‐Gang Xie, Ru‐Rong Ji · 2015 · Journal of Clinical Investigation
Stem Cell Therapy in Heart Diseases – Cell Types, Mechanisms and Improvement Strategies
Paula Müller, Heiko Lemcke, Robert David · 2018 · Cellular Physiology and Biochemistry
Prostaglandin E2 hydrogel improves cutaneous wound healing via M2 macrophages polarization
Shuaiqiang Zhang, Yuanyuan Liu, Xin Zhang, Dashuai Zhu, Xin Qi, Xiaocang Cao, Yihu Fang, Yongzhe Che, Zhongchao Han, Zuo‐Xiang He et al. · 2018 · Theranostics
Mesenchymal Stem Cell-Mediated Effects of Tumor Support or Suppression
Ki‐Jong Rhee, Jong Eun Lee, Young Woo Eom · 2015 · International Journal of Molecular Sciences
Damage-associated molecular patterns in trauma
Borna Relja, Walter Gottlieb Land · 2019 · European Journal of Trauma and Emergency Surgery
Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model
G. Desando, C. Cavallo, F. Sartoni, L. Martini, A. Parrilli, F. Veronesi, M. Fini, R. Giardino, A. Facchini, B. Grigolo · 2013 · Arthritis Research & Therapy
Adipose-derived mesenchymal stromal cells induce immunomodulatory macrophages which protect from experimental colitis and sepsis
Per O. Anderson, Luciana Souza‐Moreira, Maria H. Morell, Marta Caro, Francisco O’Valle, Elena González‐Rey, Mario Delgado · 2012 · Gut
Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severe E. coli pneumonia
Jeong-Hyun Park, Seonguk Kim, Hyungsun Lim, Airan Liu, Shuling Hu, Jae Hoon Lee, Hanjing Zhuo, Hao Qi, Michael A. Matthay, Jae Woo Lee · 2018 · Thorax
Immunomodulatory properties of mesenchymal stromal cells: an update
Müller, Luise, Tunger, Antje, Wobus, Manja, von Bonin, Malte, Towers, Russell, Bornhäuser, Martin, Dazzi, Francesco, Wehner, Rebekka, Schmitz, Marc · 2021 · Frontiers in Cell and Developmental Biology
Mesenchymal stem cell secretome for regenerative medicine: Where do we stand?
Trigo, Catarina M., Rodrigues, Joana S., Camões, Sérgio P., Solá, Susana, Miranda, Joana P. · 2025 · Journal of Advanced Research
IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties
Liming Du, Liangyu Lin, Qing Li, Keli Liu, Yin Huang, Xuefeng Wang, Kai Cao, Xiaodong Chen, Wei Cao, Fengying Li et al. · 2019 · Cell Metabolism
The immunomodulatory function of mesenchymal stem cells: mode of action and pathways
Antonio Uccelli, Nicole Kerlero de Rosbo · 2015 · Annals of the New York Academy of Sciences
Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases
Monsel, Antoine, Zhu, Ying-gang, Gudapati, Varun, Lim, Hyungsun, Lee, Jae W. · 2016 · Expert Opinion on Biological Therapy
Mesenchymal Stem Cell Microvesicles Attenuate Acute Lung Injury in Mice Partly Mediated by Ang-1 mRNA
Xiao-Dan Tang, Lin Shi, Antoine Monsel, Xiangyang Li, Huili Zhu, Yinggang Zhu, Jieming Qu · 2017 · Stem Cells
Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration
Jiaying Liu, Bin Chen, Jun Bao, Yangheng Zhang, Lang Lei, Fuhua Yan · 2019 · Stem Cell Research & Therapy
Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo
Michael C. W. Chan, Denise I. T. Kuok, Connie Y. H. Leung, Kenrie P. Y. Hui, Sophie A. Valkenburg, Eric H. Y. Lau, John Malcolm Nicholls, Xiaohui Fang, Yi Guan, Jae Woo Lee et al. · 2016 · Proceedings of the National Academy of Sciences
Mesenchymal stem cell‐derived factors: Immuno‐modulatory effects and therapeutic potential
Vladislav Volarević, Marina Gazdic, Bojana Simović Marković, Nemanja U. Jovicic, Valentin Djonov, Nebojša Arsenijević · 2017 · BioFactors
A scaffold laden with mesenchymal stem cell-derived exosomes for promoting endometrium regeneration and fertility restoration through macrophage immunomodulation.
L. Xin, Xiao-Na Lin, Feng Zhou, Chao Li, Xiufen Wang, Hua-Ying Yu, Yibin Pan, Haiyi Fei, Lie Ma, Song-Ying Zhang · 2020 · Acta Biomaterialia
Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway
Luz-Crawford, Patricia, Noël, Danièle, Fernandez, Ximena, Khoury, Maroun, Figueroa, Fernando, Carrión, Flavio, Jorgensen, Christian, Djouad, Farida · 2012 · PLoS ONE
Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat
James Devaney, Shahd Horie, Claire H. Masterson, Stephen J. Elliman, Frank Barry, Timothy O’Brien, Gerard F. Curley, Daniel P. O’Toole, John Gerard Laffey · 2015 · Thorax
The multifaceted role of mesenchymal stem cells in cancer
Michael Timaner, Kelvin K. Tsai, Yuval Shaked · 2019 · Seminars in Cancer Biology
Mesenchymal stem cell-based therapy of inflammatory lung diseases: current understanding and future perspectives
Harrell, C. Randall, Sadikot, Ruxana, Pascual, Jose, Fellabaum, Crissy, Jankovic, Marina Gazdic, Jovicic, Nemanja, Djonov, Valentin, Arsenijevic, Nebojsa, Volarevic, Vladislav · 2019 · Stem Cells International
Mesenchymal Stem Cells (MSC) Derived from Induced Pluripotent Stem Cells (iPSC) Equivalent to Adipose-Derived MSC in Promoting Intestinal Healing and Microbiome Normalization in Mouse Inflammatory Bowel Disease Model
Sirikul Soontararak, Lyndah Chow, Valerie Johnson, Jonathan W. Coy, William H. Wheat, Daniel P. Regan, STEVEN W. DOW · 2018 · Stem Cells Translational Medicine
Modulation of Adult Mesenchymal Stem Cells Activity by Toll-Like Receptors: Implications on Therapeutic Potential
Olga DelaRosa, Eleuterio Lombardo · 2010 · Mediators of Inflammation
Mesenchymal Stromal Cells Improve Survival During Sepsis in the Absence of Heme Oxygenase-1: The Importance of Neutrophils
Sean R. R. Hall, Konstantin Tsoyi, Bonna Ith, Robert F. Padera, James Arthur Lederer, Zhihong Wang, Xiaoli Liu, Mark A. Perrella · 2012 · Stem Cells
Cell Senescence Abrogates the Therapeutic Potential of Human Mesenchymal Stem Cells in the Lethal Endotoxemia Model
Juan Carlos Sepúlveda, María Tomé, María Eugenia Fernández‐Santos, Mario Delgado, Judith Campisi, António Bernad, Manuel A. Gonzalez · 2014 · Stem Cells
Aging Mesenchymal Stem Cells Fail to Protect Because of Impaired Migration and Antiinflammatory Response
Martha L. Bustos, Luai Huleihel, Maria G. Kapetanaki, Christian Lacks Lino Cardenas, Lyle Mroz, Bryon M. Ellis, Bryan J. McVerry, Thomas J. Richards, Naftali Kaminski, Nayra Cerdenes et al. · 2014 · American Journal of Respiratory and Critical Care Medicine
Extracellular Vesicle-Educated Macrophages Promote Early Achilles Tendon Healing
Connie S. Chamberlain, Anna E. B. Clements, John A. Kink, Ugeun Choi, Geoffrey S. Baer, Matthew Aaron Halanski, Peiman Hematti, Ray Vanderby · 2019 · Stem Cells
Paracrine Factors of Multipotent Stromal Cells Ameliorate Lung Injury in an Elastase-induced Emphysema Model
Ahmed M. Katsha, Shinya Ohkouchi, Hong Xin, Masahiko Kanehira, Ruowen Sun, Toshihiro Nukiwa, Yasuo Saijo · 2010 · Molecular Therapy
Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway
Binggang Xiang, Guoying Zhang, Ling Guo, Xiang‐An Li, Andrew J. Morris, Alan Daugherty, Sidney W. Whiteheart, Susan S. Smyth, Zhenyu Li · 2013 · Nature Communications
Mitochondria in mesenchymal stem cell biology and cell therapy: From cellular differentiation to mitochondrial transfer
Yi‐Chao Hsu, Yuting Wu, Ting-Hsien Yu, Yau‐Huei Wei · 2016 · Seminars in Cell and Developmental Biology
Mesenchymal Stem Cell‐Based Therapy for Kidney Disease: A Review of Clinical Evidence
Anna Julie Peired, Alessandro Sisti, Paola Romagnani · 2016 · Stem Cells International
Mechanisms of Endothelial Regeneration and Vascular Repair and Their Application to Regenerative Medicine
Colin E. Evans, M. Luisa Iruela‐Arispe, You‐Yang Zhao · 2020 · American Journal Of Pathology
TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo
Ryang Hwa Lee, Ji Min Yu, Andrea M. Foskett, Grant Peltier, John C. Reneau, Nikolay Bazhanov, Joo Youn Oh, Darwin J. Prockop · 2014 · Proceedings of the National Academy of Sciences
TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury
Manish Mittal, Chinnaswamy Tiruppathì, Saroj Nepal, You‐Yang Zhao, Dagmara Grzych, Dheeraj Soni, Darwin J. Prockop, Asrar B. Malik · 2016 · Proceedings of the National Academy of Sciences
Toll-Like Receptors as Modulators of Mesenchymal Stem Cells
Olga DelaRosa, Wilfried Dalemans, Eleuterio Lombardo · 2012 · Frontiers in Immunology
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence
Saul, Dominik, Khosla, Sundeep · 2022 · Endocrine Reviews